Clinical Trials on Colorectal Neoplasms, Malignant

Total 107163 results

Sheba Medical Center
Bristol-Myers Squibb; Checkmate Pharmaceuticals

Completed

Combined Immunotherapy and Radiosurgery for Metastatic Colorectal Cancer

Liver Metastases | Colorectal Neoplasms Malignant

Israel
M.D. Anderson Cancer Center

Active, not recruiting

Avelumab and M6620 for the Treatment of DDR Deficient Metastatic or Unresectable Solid Tumors

Refractory Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
Barbara Ann Karmanos Cancer Institute

Completed

Anti-CD3 x Anti-Erbitux® Armed Activated T Cells (Phase Ib) for Gastrointestinal (GI Cancer)

Colorectal Cancer | Pancreatic Cancer | Colon Carcinoma | Cancer of Pancreas | Pancreatic Neoplasm | Malignant Neoplasm of Large Intestine | Cancer of Colon | Malignant Tumor of Colon

United States
Sun Yat-sen University

Recruiting

Localized Treatment Versus Palliative Chemotherapy in CRC Patients With 10 or More CRLM

Colorectal Neoplasms Malignant

China
Shanghai Zhongshan Hospital

Recruiting

Tislelizumab Plus Cetuximab and Irinotecan vs Third-line Standard-of-care in Refractory mCRC

Colorectal Neoplasms Malignant

China
National Cancer Institute (NCI)

Recruiting

Study of Chemotherapy Plus Ipatasertib for People With Solid Tumors With AKT Mutations, A ComboMATCH Treatment Trial

Locally Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States, Puerto Rico
University of California, San Francisco

Completed

Integrative Palliative Care/Psycho-Oncology Telehealth Intervention in Patients With Advanced Cancer

Advanced Malignant Solid Neoplasm | Locally Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
Abramson Cancer Center at Penn Medicine
Pfizer

Terminated

TACE Plus Axitinib and Hydroxychlorquine for Liver-Dominant Metastatic Colorectal Cancer (CRC) (TACE-Ax-HCQ)

Colorectal Neoplasms Malignant

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Completed

Pre-Test Genetic Education and Remote Genetic Counseling in Communicating Tumor Profiling Results to Patients With Advanced Cancer

Advanced Malignant Neoplasm | Locally Advanced Malignant Neoplasm

United States
OHSU Knight Cancer Institute
Oregon Health and Science University; Eisai Inc.

Active, not recruiting

Eribulin and Radiation Therapy in Treating Patients With Retroperitoneal Liposarcoma That Can Be Removed by Surgery

Malignant Solid Neoplasm | Liposarcoma | Malignant Abdominal Neoplasm | Malignant Retroperitoneal Neoplasm | Malignant Scrotal Neoplasm | Malignant Spermatic Cord Neoplasm

United States
M.D. Anderson Cancer Center

Terminated

Pevonedistat and Pembrolizumab for the Treatment of dMMR/MSI-H Metastatic or Locally Advanced Unresectable Solid Tumor

Locally Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
Fundació Institut Germans Trias i Pujol
Hospital General Universitario Gregorio Marañon; Hospital Clinic of Barcelona; Hospital General Universitario Elche and other collaborators

Unknown

Endoscopic Full-Thickness Resection In Colon (EFTRICOM)

Colorectal Neoplasms | Colorectal Cancer | Colo-rectal Cancer | Colonic Cancer | Colorectal Adenocarcinoma | Colon Polyp | Colon Neoplasm, Malignant | Colonic Adenoma | Colon Lesion | Colon Neoplasm

Spain
Oslo University Hospital
University of Oslo; Helse Stavanger HF; Haukeland University Hospital; St. Olavs... and other collaborators

Recruiting

Simultaneous vs. Staged Resection of Colorectal Cancer With Synchronous Liver Metastases (SYLMET)

Colorectal Cancer | Liver Metastases | Liver Metastasis Colon Cancer | Colorectal Neoplasms Malignant

Norway
National Cancer Institute (NCI)

Recruiting

Testing the Combination of Anti-cancer Drugs Atezolizumab and Tiragolumab in People With Advanced Stage Rare Cancers, RARE3 Trial

Advanced Rare Malignant Solid Neoplasm | Rare Malignant Solid Neoplasm | Refractory Rare Malignant Solid Neoplasm

United States
Assistance Publique - Hôpitaux de Paris
Federation Francophone de Cancerologie Digestive; UNICANCER; Merck Serono S.A... and other collaborators

Unknown

Trial of Neoadjuvant Chemotherapy in Locally Advanced Colon Cancer (ECKINOXE)

Colon Cancer | Locally Advanced Malignant Neoplasm

France
Cancer Institute and Hospital, Chinese Academy...

Unknown

Phase II Study of Preoperative IMRT Combined With Capecitabine and Bevacizumab in Locally Advanced Rectal Cancer

Locally Advanced Malignant Neoplasm

China
M.D. Anderson Cancer Center

Completed

Psychological, Psychophysical and Epigenetic Determinants of Chronic Pain After Cytoreductive - Hyperthermic Intraoperative Chemotherapy

Malignant Solid Neoplasm | Gastric Carcinoma | Malignant Peritoneal Neoplasm | Colorectal Carcinoma | Carcinomatosis | Appendix Carcinoma

United States
National Cancer Institute (NCI)

Not yet recruiting

Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)

Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm
National Cancer Institute (NCI)

Recruiting

Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes

Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
M.D. Anderson Cancer Center

Recruiting

Cabozantinib and Pamiparib for the Treatment of Advanced of Refractory Solid Tumors

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm

United States
National Cancer Institute (NCI)

Active, not recruiting

Pembrolizumab and Recombinant Interleukin-12 in Treating Patients With Solid Tumors

Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Ribociclib and Gemcitabine Hydrochloride in Treating Patients With Advanced or Metastatic Solid Tumors

Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
University of Southern California
National Cancer Institute (NCI)

Recruiting

FID-007 in Treating Participants With Advanced Solid Tumors

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm

United States
National Cancer Institute (NCI)

Completed

AZD1775 in Treating Patients With Advanced Refractory Solid Tumors With CCNE1 Amplification

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Videos and Questionnaires in Assessing Patient Perception of Physician's Compassion, Communication Skills, and Professionalism During Clinic Visits

Malignant Neoplasm | Metastatic Malignant Neoplasm | Advanced Malignant Neoplasm | Recurrent Malignant Neoplasm | Locally Advanced Malignant Neoplasm

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Sacral Nerve Stimulation in Treating Low Anterior Resection Syndrome or Fecal Incontinence in Patients With Locally Advanced Rectal Cancer or Other Pelvic Cancer, the RESTORE Study

Low Anterior Resection Syndrome | Malignant Uterine Neoplasm | Rectal Carcinoma | Malignant Ovarian Neoplasm | Malignant Pelvic Neoplasm | Malignant Anal Neoplasm | Malignant Bladder Neoplasm | Malignant Cervical Neoplasm | Malignant Prostate Neoplasm | Malignant Vaginal Neoplasm | Malignant Vulvar Neoplasm

United States
National Cancer Institute (NCI)

Not yet recruiting

Testing How the Body Responds to the Drug CBX-12 in Patients With Advanced Solid Cancers

Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm
National Cancer Institute (NCI)

Recruiting

Testing the Use of AMG 510 (Sotorasib) and Panitumumab as a Targeted Treatment for KRAS G12C Mutant Solid Tumor Cancers (A ComboMATCH Treatment Trial)

Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
National Cancer Institute (NCI)

Suspended

Testing the Use of Nilotinib and Paclitaxel as a Treatment for Patients With Prior Taxane Treatment, A ComboMATCH Treatment Trial

Refractory Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors

Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Recurrent Cutaneous Melanoma | Recurrent Malignant Female Reproductive System Neoplasm | Refractory Malignant Female Reproductive System Neoplasm | Recurrent Lip and Oral Cavity Carcinoma | Recurrent Malignant Endocrine... and other conditions

United States
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Total Mesorectal Excision(TME) With Lateral Lymph Node Dissection Versus TME After Neoadjuvant Chemo-radiotherapy (TELEPHOME)

Rectal Neoplasm Malignant

China
Washington University School of Medicine

Completed

Study of Saline Linked Monopolar Surface Radiofrequency (RF) Ablation of Hepatic Tumors

Malignant Liver Tumors | Liver Metastases From Colorectal Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Financial Distress in Advanced Cancer Patients

Metastatic Malignant Neoplasm | Advanced Malignant Neoplasm | Recurrent Malignant Neoplasm | Refractory Malignant Neoplasm | Locally Advanced Malignant Neoplasm

United States
OHSU Knight Cancer Institute
Oregon Health and Science University; Incyte Corporation

Not yet recruiting

Axatilimab in Combination With Retifanlimab and Paclitaxel for the Treatment of Patients With Advanced or Metastatic Solid Tumors

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

Does the Use of a Genomic Tumor Board Increase the Number of Patients Who Receive Genome-Informed Treatment

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States, Puerto Rico
National Cancer Institute (NCI)

Active, not recruiting

Trametinib in Treating Patients With Advanced Cancer With or Without Hepatic Dysfunction

Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Metastatic Malignant Neoplasm in the Liver | Unresectable Solid Neoplasm

United States, Canada
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Larotrectinib for the Treatment of NTRK Amplification Positive, Locally Advanced or Metastatic Solid Tumors

Locally Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
European Association for Endoscopic Surgery

Completed

Enteral Stents for Colonic Obstruction (ESCO)

Malignant Colorectal Obstruction

Spain, Italy
National Cancer Institute (NCI)

Completed

Cancer Vaccine Targeting Brachyury Protein in Tumors

Neoplasms | Adenocarcinoma | Colon Neoplasms | Malignant Solid Tumors

United States
National Cancer Institute (NCI)

Terminated

Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Stage IV Melanoma

Recurrent Melanoma | Stage IV Melanoma | Acral Lentiginous Malignant Melanoma | Lentigo Maligna Malignant Melanoma | Nodular Malignant Melanoma | Solar Radiation-related Skin Melanoma | Superficial Spreading Malignant Melanoma

United States
M.D. Anderson Cancer Center

Terminated

SAR439459 and Cemiplimab for the Treatment of Advanced or Unresectable Solid Tumors, Strategic Alliance, TACTIC TRIAL

Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
Aalborg University Hospital

Active, not recruiting

Chemo-radiotherapy as Main Treatment Strategy for Rectal Cancer. Can we Provide a More Precise and Effective Treatment (AMPERE)

Rectal Cancer | Rectal Adenocarcinoma | Locally Advanced Malignant Neoplasm

Denmark
M.D. Anderson Cancer Center
Novartis; AstraZeneca; MedImmune LLC

Completed

Study of Durvalumab (MEDI4736) (Anti-PD-L1) and Trametinib (MEKi) in MSS Metastatic Colon Cancer

Colorectal Cancer | Colon Cancer | Malignant Neoplasms of Digestive Organs

United States
Wageningen University
Dutch Cancer Society; Wereld Kanker Onderzoek Fonds; Funding: World Cancer Research... and other collaborators

Recruiting

The COLON Study: Colorectal Cancer Cohort (COLON)

Colorectal Neoplasms Malignant

Netherlands
Intuitive Surgical

Active, not recruiting

da Vinci SP® Investigational Device Exemption Study in Colorectal Procedures

Colorectal Cancer | Benign or Malignant Rectal or Colon Tumors

United States, Korea, Republic of
Qilu Hospital of Shandong University

Not yet recruiting

Chemoradiotherapy Sequenced Radical Surgery for Colorectal Cancer With PALNM

Chemoradiotherapy | Colorectal Neoplasms Malignant | Lymph Node Excision

China
Mirati Therapeutics Inc.
Boehringer Ingelheim

Completed

Adagrasib in Combination With BI 1701963 in Patients With Cancer (KRYSTAL 14)

Metastatic Cancer | Advanced Cancer | Malignant Neoplasm of Colon | Malignant Neoplasm of Lung | Malignant Neoplastic Disease

United States
Immanuel Kant Baltic Federal University
Center of Endourology "Endocenter"

Recruiting

Factors Affecting the Results of Treatment of Patients With Colorectal Cancer

Colorectal Cancer | Rectal Cancer | Colon Cancer | Colorectal Adenocarcinoma | Rectal Adenocarcinoma | Colorectal Neoplasms Malignant

Russian Federation
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Preference of Room Setting and Waiting Time in Patients With Advanced, Locally Advanced, or Metastatic Cancer and Their Caregivers Who Are Seen in the Outpatient Supportive/Palliative Care Center

Metastatic Malignant Neoplasm | Caregiver | Advanced Malignant Neoplasm | Locally Advanced Malignant Neoplasm

United States
Ronald Levy
Bristol-Myers Squibb

Completed

SD-101 and BMS-986178 in Treating Patients With Advanced or Metastatic Solid Malignancies

Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Extracranial Solid Neoplasm

United States

Clinical Trials on Colorectal Neoplasms, Malignant

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