Clinical Trials on Colorectal Carcinoma (CRC) Patients in United States

Total 838 results

National Cancer Institute (NCI)

Recruiting

Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Stage IV Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Metastatic Microsatellite Stable Colorectal Carcinoma | Advanced Microsatellite Stable Colorectal Carcinoma | Hematopoietic and Lymphatic System...

United States
University of Southern California
National Cancer Institute (NCI)

Recruiting

Detection of MSI in Circulating Tumor DNA of Colorectal Carcinoma Patients

Microsatellite Instability | Colorectal Cancer Stage IV

United States
University of California, San Francisco
Bristol-Myers Squibb; Pfizer

Terminated

Encorafenib, Binimetinib, and Nivolumab in Treating Microsatellite Stable BRAF V600E Metastatic Colorectal Cancer

Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Metastatic Colorectal Adenocarcinoma | Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage IIIC Colon Cancer | Stage IV Colon Cancer | Stage IV Rectal... and other conditions

United States
Dartmouth-Hitchcock Medical Center

Terminated

Effect of Sorafenib or Regorafenib on P63 Expression and Keratinocyte Differentiation in Human Skin

Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Carcinoma

United States
Emory University
Ipsen; Taiho Oncology, Inc.

Recruiting

TAS102 in Combination With NAL-IRI in Advanced GI Cancers

Gastric Adenocarcinoma | Unresectable Pancreatic Carcinoma | Metastatic Pancreatic Adenocarcinoma | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Colorectal Adenocarcinoma | Stage IV Gastric Cancer | Stage IV Colorectal Cancer | Stage IVA Colorectal Cancer | Stage IVB Colorectal Cancer | Stage... and other conditions

United States
Biogen

Terminated

Safety and Activity of 90Y-Labeled IDEC-159 in Subjects With Metastatic Colorectal Adenocarcinoma

Colorectal Cancer | Metastases

United States
National Cancer Institute (NCI)

Withdrawn

Prospective Randomized Trial Evaluating Mandatory Second Look Surgery With HIPEC and CRS vs. Standard of Care in Subjects at High Risk of Developing Colorectal Peritoneal Metastases

Peritoneal Carcinomatosis | Colorectal Carcinoma

United States
Gilead Sciences

Completed

Safety Study of hMN14 to Treat Either Colorectal or Breast Cancer

Breast Cancer | Breast Neoplasms | Colorectal Neoplasms | Colorectal Cancer | Rectal Cancer | Colon Cancer | Colorectal Carcinoma

United States
Gradalis, Inc.

Terminated

Randomized Phase II Adjuvant Chemotherapy ± FANG™ in Colorectal Carcinoma With Liver Metastases (FANG-CLM)

Colon Cancer

United States
Biogen

Completed

Interferon-Beta Gene Transfer (Ad.hIFN-β) as Treatment for Refractory Colorectal Carcinoma With Liver Metastases

Colorectal Carcinoma | Metastases

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Self-Management Survivorship Care in Stage I-III Non-small Cell Lung Cancer or Colorectal Cancer

Lung Non-Small Cell Carcinoma | Stage III Lung Cancer AJCC v8 | Stage II Lung Cancer AJCC v8 | Stage IIA Lung Cancer AJCC v8 | Stage IIB Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Stage IIIA Colorectal Cancer AJCC v8 | Stage... and other conditions

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI); Oregon Health and Science University

Completed

EXERCISING TOGETHER for Couples Coping With Cancer

Malignant Solid Neoplasm | Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Breast Carcinoma | Colorectal Carcinoma | Prostate Carcinoma | Stage I Prostate Cancer AJCC v8 | Stage II Prostate Cancer AJCC v8 | Stage III Prostate... and other conditions

United States
M.D. Anderson Cancer Center

Completed

Psychological, Psychophysical and Epigenetic Determinants of Chronic Pain After Cytoreductive - Hyperthermic Intraoperative Chemotherapy

Malignant Solid Neoplasm | Gastric Carcinoma | Malignant Peritoneal Neoplasm | Colorectal Carcinoma | Carcinomatosis | Appendix Carcinoma

United States
Memorial Sloan Kettering Cancer Center
Bayer; State University of New York - Downstate Medical Center; Queens Cancer...

Active, not recruiting

Regorafenib in Good Performance Status Patients With Newly Diagnosed Metastatic Colorectal Adenocarcinoma

Metastatic Colorectal Adenocarcinoma

United States
Bristol-Myers Squibb
Novartis

Active, not recruiting

An Investigational Immuno-therapy Study Of Nivolumab In Combination With Trametinib With Or Without Ipilimumab In Participants With Previously Treated Cancer of the Colon or Rectum That Has Spread (CheckMate 9N9)

Colorectal Cancer | Colorectal Neoplasm | Colorectal Tumors | Colorectal Carcinoma

Italy, United States, Canada, Spain, Argentina, Australia, Belgium, Chile, Czechia, Germany
Daiichi Sankyo, Inc.

Completed

DJ-927 as Second-Line Therapy in Treating Patients With Progressive Locally Advanced or Metastatic Colorectal Adenocarcinoma

Colorectal Cancer

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...

Terminated

Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Metastatic Colorectal Adenocarcinoma

Metastatic Colorectal Adenocarcinoma

United States, Netherlands
University of Utah

Completed

Home-based HIIT to Improve CRC Survivorship: Feasibility and Relationship With Novel Surrogate Biomarkers of CRC Recurrence

Colorectal Neoplasms | Colorectal Cancer | Rectal Cancer | Rectal Neoplasms | Colonic Neoplasms | Colonic Cancer | Colorectal Carcinoma

United States
James A. Haley Veterans Administration Hospital
Hoffmann-La Roche

Terminated

Capecitabine (Xeloda) and Radiation for Patients With Rectosigmoid Carcinoma

Colorectal Cancer

United States
Georgetown University
National Cancer Institute (NCI); Mayo Clinic; Emory University; Indiana University and other collaborators

Terminated

Durvalumab Plus CV301 With Maintenance Chemotherapy in Metastatic Colorectal or Pancreatic Adenocarcinoma

Metastatic Colorectal Cancer | Pancreatic Adenocarcinoma | Colorectal Adenocarcinoma | Metastatic Pancreatic Cancer

United States
Emory University

Completed

Legume Diet Satiety Pilot Study

Obesity | Colorectal Carcinoma

United States
Tulane University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Building Engagement Using Financial Incentives Trial - Colorectal Cancer Screening (BENEFIT-C)

COVID-19 | Colorectal Cancer | Influenza | Health Behavior | Vaccine-Preventable Diseases | Vaccine Hesitancy | Healthcare Patient Acceptance

United States
Eli Lilly and Company

Completed

A Study of Irinotecan Plus Cetuximab With or Without Enzastaurin in Participants With Colorectal Cancer

Colorectal Cancer | Colorectal Carcinoma | Colorectal Tumor

United States
Anwaar Saeed
AstraZeneca; Exelixis

Active, not recruiting

Cabozantinib Plus Durvalumab With or Without Tremelimumab in Patients With Gastroesophageal Cancer and Other Gastrointestinal Malignancies (CAMILLA)

Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Esophageal Adenocarcinoma

United States
University of Southern California
National Cancer Institute (NCI)

Withdrawn

Nutritional Preferences and Product Accessibility in Oral Nutritional Supplements in Participants With Breast, Colorectal, Upper Gastrointestinal, or Prostate Cancer

Cholangiocarcinoma | Breast Carcinoma | Gastric Carcinoma | Colorectal Carcinoma | Pancreatic Carcinoma | Prostate Carcinoma | Malignant Digestive System Neoplasm

United States
National Cancer Institute (NCI)

Active, not recruiting

Selumetinib and Cyclosporine in Treating Patients With Advanced Solid Tumors or Advanced or Metastatic Colorectal Cancer

Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Recurrent Colorectal Carcinoma | Stage IIIA Colorectal Cancer AJCC v7 | Stage IIIB Colorectal Cancer AJCC v7 | Stage IIIC Colorectal Cancer AJCC v7 | Solid Neoplasm

United States, Canada
University of California, San Francisco
National Cancer Institute (NCI)

Completed

Lay Health Worker Outreach in Increasing Colorectal Cancer Screening in Asian Americans

Colorectal Carcinoma | Healthy Subject | Health Status Unknown

United States
Symphogen A/S

Terminated

Sym004 Versus Futuximab or Modotuximab in Patients With mCRC

Carcinoma | Metastatic Colorectal Cancer | Colorectal Cancer Metastatic

United States, Spain, Germany, Italy
Navidea Biopharmaceuticals
National Cancer Institute (NCI); National Institutes of Health (NIH)

Terminated

An Evaluation of Tilmanocept by IV Injection Using SPECT/CT vs PET Imaging in Subjects With Liver Metastases.

Liver Metastases | Colorectal Carcinoma

United States
Memorial Sloan Kettering Cancer Center
Bristol-Myers Squibb

Active, not recruiting

Temozolomide, Cisplatin, and Nivolumab in People With Colorectal Cancer

Colorectal Adenocarcinoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Microwave Ablation or Wedge Resection for the Treatment of Lung, Sarcoma and Colorectal Lesions, ALLUME Study

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Lung Non-Small Cell Carcinoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage II Lung Cancer AJCC v8 | Stage IIA Lung Cancer AJCC v8 | Stage IIB Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung... and other conditions

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI); Oregon Health and Science University; Kaiser... and other collaborators

Completed

CATCH-UP Intervention in Increasing Cancer Screening and Prevention Care in Uninsured Patients at Community Health Centers

Breast Carcinoma | Cervical Carcinoma | Colorectal Carcinoma | Malignant Neoplasm | Human Papillomavirus Infection | Health Status Unknown

United States
University of Texas Southwestern Medical Center
Exelixis

Recruiting

Sequential Treatment of Cabozantinib or Cabozantinib With Nivolumab for Advanced Renal Cell Carcinoma (RCC)

Renal Cell Carcinoma | RCC

United States
Mologen AG

Completed

Efficacy Study of a Maintenance Therapy With Immunomodulator MGN1703 in Patients With Advanced Colorectal Carcinoma (IMPACT)

Advanced Colorectal Carcinoma

United Kingdom, Germany, Austria, Czech Republic, France, Russian Federation
Celldex Therapeutics

Terminated

A Dose Escalation, Safety and Activity Study of CDX-014 in Patients With Renal Cell Carcinoma and Ovarian Clear Cell Carcinoma

Kidney Neoplasms | Metastatic Renal Cell Carcinoma | Ovarian Clear Cell Carcinoma | Papillary Renal Cell Carcinoma | Renal Cell Carcinoma (RCC) | Clear-cell Renal Cell Carcinoma

United States
Fred Hutchinson Cancer Center
Affini-T Therapeutics, Inc.

Recruiting

Autologous CD8+ and CD4+ Transgenic T Cells Expressing High Affinity KRASG12V Mutation-Specific T Cell Receptors (FH-A11KRASG12V-TCR) in Treating Patients With Metastatic Pancreatic, Colorectal and Non-Small Cell Lung Cancers With KRAS G12V Mutations

Metastatic Lung Non-Small Cell Carcinoma | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Metastatic Colorectal Adenocarcinoma | Stage IV Lung Cancer AJCC v8 | Stage IV Colorectal Cancer AJCC v8

United States
Akamis Bio
Bristol-Myers Squibb; Syneos Health

Completed

Phase I Study of Enadenotucirev and PD-1 Inhibitor in Subjects With Metastatic or Advanced Epithelial Tumors (SPICE)

Colorectal Cancer | Squamous Cell Carcinoma of the Head and Neck | Epithelial Tumor

United States
Cancer Advances Inc.

Completed

Study to Assess Safety and Tolerability of G17DT in Patients With Colorectal Adenocarcinoma. (CC1A&B)

Colorectal Cancer

United Kingdom
Cascadian Therapeutics Inc.

Completed

Phase 1 and 2 Study of PX-866 and Cetuximab

Incurable Metastatic Colorectal Carcinoma | Incurable Progressive, Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

United States, Canada
Memorial Sloan Kettering Cancer Center
Bristol-Myers Squibb

Completed

Study of Prophylactic Topical Dapsone 5% Gel Versus Moisturizer for Cetuximab-induced Papulopustular (Acneiform) Rash in Patients With mCRC or HNSCC Without Previous or Concurrent RT

Cetuximab-induced Papulopustular (Acneiform) Rash Who Have | Metastatic Colorectal Cancer or Head and Neck Squamous Cell Carcinoma

United States
University of North Carolina, Chapel Hill
Duke University; Agency for Healthcare Research and Quality (AHRQ)

Completed

Elders Preferences in Care Decisions (EPIC-D)

Colon Cancer | Decision Making | Patient-Centered Care | Early Detection of Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Personalized Peptide Vaccine in Treating Patients With Advanced Pancreatic Cancer or Colorectal Cancer

Stage IV Pancreatic Cancer AJCC v6 and v7 | Metastatic Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Metastatic Pancreatic Ductal Adenocarcinoma

United States
Boehringer Ingelheim

Recruiting

A Study to Test Different Doses of BI 764532 in Patients With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for DLL3

Patients With Small Cell Lung Carcinoma and Other Neoplasms

United States, Spain, Germany, Japan
Incyte Corporation

Completed

A Phase 1/2 Study of INCB001158 in Combination With Chemotherapy in Subjects With Solid Tumors

Ovarian Cancer | Endometrial Cancer | Solid Tumors | Biliary Tract Cancer (BTC) | Colorectal Cancer (CRC) | Gastroesophageal Cancer (GC)

United Kingdom, United States, Belgium
Daiichi Sankyo, Inc.

Terminated

CS-1008 Used With Irinotecan Versus Irinotecan Alone in Subjects With Metastatic Colorectal Carcinoma Who Failed First-line Treatment With Oxaliplatin

Metastatic Colorectal Cancer

United Kingdom
Roswell Park Cancer Institute
National Comprehensive Cancer Network

Active, not recruiting

TAS-102, Irinotecan, and Bevacizumab for the Treatment of Pre-treated Metastatic or Unresectable Colorectal Cancer, the TABAsCO Study

Metastatic Colon Adenocarcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC v8 | Stage IIIC Colon Cancer AJCC v8 | Stage IV Colon Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC... and other conditions

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Thalidomide in Treating Patients Who Have Undergone Surgery and Chemotherapy for Cancer That Has Spread Throughout the Abdomen Due to Colorectal Cancer or Appendix Cancer

Colorectal Cancer | Carcinoma of the Appendix

United States
Hoffmann-La Roche

Completed

A Phase Ib Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Cibisatamab in Combination With Atezolizumab After Pretreatment With Obinutuzumab in Participants With Previously Treated Metastatic Colorectal Adenocarcinoma

Colorectal Cancer

United States, France, Denmark, Spain
The Rogosin Institute
Vital Systems Inc.

Completed

Open-Label Phase 2 Efficacy Trial of Cancer Macrobeads in Patients With Treatment-Resistant Pancreatic/Colorectal Cancer (Macrobead)

Colorectal Cancer Metastatic | Pancreatic Adenocarcinoma Metastatic | Pancreatic Adenocarcinoma Non-resectable

United States
Genzyme, a Sanofi Company

Completed

Phase I Irinotecan, 5-Fluorouracil and Leucovorin Combination

Adenocarcinoma | Metastatic | Colorectal

United Kingdom, Belgium

Clinical Trials on Colorectal Carcinoma (CRC) Patients in United States

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