Clinical Trials on Complement Deficiency

Total 9076 results

Azienda Ospedaliero-Universitaria di Modena

Completed

Gonadal Function in Young to Middle Aged HIV-infected Men

Erectile Dysfunction | Human Immunodeficiency Virus | Hypogonadism, Male

Italy
Joanne Jeter
National Cancer Institute (NCI)

Active, not recruiting

Nivolumab in Preventing Colon Adenomas in Participants With Lynch Syndrome and a History of Partial Colectomy

Lynch Syndrome | Colon Adenoma | Colon Carcinoma | MLH1 Gene Mutation | MSH2 Gene Mutation

United States
Hasselt University
Ziekenhuis Oost-Limburg

Completed

Reaching Out to the UNdiagnosed People Infected With Blood Borne Viral Infections (RUNtoBBV)

Hepatitis B | Human Immunodeficiency Virus | Hepatitis c

Belgium
Yale University
The New York Academy of Medicine

Completed

Buprenorphine and Integrated HIV Care

HIV Infections | Human Immunodeficiency Virus | Substance-related Disorders | Drug Addiction | AIDS

United States
Spruce Biosciences

Completed

Study to Evaluate the Safety and Efficacy of SPR001 in Subjects With Classic Congenital Adrenal Hyperplasia

Congenital Adrenal Hyperplasia | CAH - Congenital Adrenal Hyperplasia | CAH - 21-Hydroxylase Deficiency

United States
Vanderbilt University Medical Center

Completed

Mental Ability Challenge Study in Adults With and Without HIV

Cognitive Impairment | Memory Impairment | HIV-1-infection | Aging, Premature | HIV-Associated Cognitive Motor Complex

United States
Tehran University of Medical Sciences
RojanPharma Pharmaceutical Company

Completed

Sofosbuvir and Daclatasvir for Treating Hepatitis C in 200 Patients Co-infected With Human Immunodeficiency Virus (HIV200)

Human Immunodeficiency Virus | Hepatitis C Virus Infection, Response to Therapy of

Iran, Islamic Republic of
Johns Hopkins University
University of North Carolina, Chapel Hill; Children's Hospital Medical Center... and other collaborators

Terminated

CPAP Improving Mortality for Pneumonia in African Children Trial (IMPACT)

Pneumonia | Malnutrition | Hypoxemia | Human Immunodeficiency Virus (HIV)

Malawi
Premier Specialists, Australia

Unknown

Using Topical Sirolimus 2% for Patients With Epidermolysis Bullous Simplex (EBS) Study

Epidermolysis Bullosa Simplex | Epidermolysis Bullosa Simplex Kobner | Weber-Cockayne Syndrome

Australia
Bristol-Myers Squibb

Withdrawn

A Phase 2b Evaluation of Daclatasvir/Sofosbuvir in Non-Cirrhotic Treatment Naive Subjects With Genotype 1, 2, 3 and 4 Chronic Hepatitis C Virus Coinfected With Human Immunodeficiency Virus (HIV-1)

Hepatitis C

France, Canada
Fundación Pública Andaluza Progreso y Salud
Gilead Sciences

Completed

Hepatic Safety of Eviplera® in HIV/Hepatitis C (HCV)-Coinfected Patients Without HCV Treatment in the "The HEPAVIR HEPATIC SAFETY Cohort." (hEPAtic)

Human Immunodeficiency Virus (HIV) Hepatitis C Virus (HCV) Coinfected Subjects

Spain
Washington University School of Medicine

Completed

Effect of Diet-induced Weight Loss on HIV-associated Metabolic Syndrome

HIV Infections | Metabolic Syndrome | HIV (Human Immunodeficiency Virus)

United States
Michael Hoelscher
University of Liverpool; National Institute for Medical Research (NIMR) - Mbeya... and other collaborators

Not yet recruiting

Increasing Neonatal HIV Test and Treat to Maximize the Long-Term Impact on Infant Health and Novel Infant Antiretroviral Treatment (LIFE2Scale)

Infant, Newborn, Diseases | Infant Death | Infant Morbidity | Vertical Human Immunodeficiency Virus Transmission | HIV Infection Pediatric

Mozambique, Tanzania
Centre Hospitalier de Saint-Denis

Recruiting

The Value of HPV Testing for Cervical Cancer Screening in Women Living With HIV (PAPILLO-VIH) (PAPILLO-VIH)

HIV Seropositivity

France
University of Massachusetts, Worcester
National Institute of Allergy and Infectious Diseases (NIAID); Aurum Institute and other collaborators

Recruiting

Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) (METHOD)

Tuberculosis | Pulmonary Tuberculosis | HIV Coinfection

South Africa
National Taiwan University Hospital
Taipei Veterans General Hospital, Taiwan

Recruiting

Hepatitis B Virus Vaccination in HIV-positive Patients and Individuals at High Risk for HIV Infection

HIV Infections | Immunization; Infection | Viral Hepatitis B

Taiwan
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System

Parkinson's Disease | Atherosclerosis | Cardiomyopathy | Li-Fraumeni Syndrome | Cardiovascular Capacity

United States
Genzyme, a Sanofi Company

Terminated

Study of the Effects of Fabrazyme Treatment on Lactation and Infants

Fabry Disease | Alpha Galactosidase A Deficiency

United States, Austria, United Kingdom
Medical University of Graz

Active, not recruiting

Severe Immune Cytopenia Registry Www.Sic-reg.Org (sic-reg)

Primary Immunodeficiency | Immune Thrombocytopenia | Autoimmune Hemolytic Anemia | Evans Syndrome

Austria
University of Pittsburgh

Completed

Genetic and Environmental Determinants That Control Metabolism in Pulmonary Hypertension

Pulmonary Hypertension | Friedreich Ataxia | Iron-sulfur Cluster Deficiency

United States
Greenwood Genetic Center

Completed

Longitudinal Studies of the Glycoproteinoses

Galactosialidosis | Sialidosis | Fucosidosis | Aspartylglucosaminuria | Alpha Mannosidosis | Beta Mannosidosis | Mucolipidosis II | Mucolipidosis III | Schindler Disease

United States
Inozyme Pharma
IQVIA Biotech

Active, not recruiting

Evaluation of Safety, Tolerability, and Efficacy of INZ-701 in Adults With ABCC6 Deficiency Causing PXE

Pseudoxanthoma Elasticum | Generalized Arterial Calcification of Infancy | ATP-Binding Cassette Subfamily C Member 6 Deficiency

United States, United Kingdom
Medical University of South Carolina
National Institute of Mental Health (NIMH); Muhimbili University of Health...

Completed

Impact of Integrated HIV/NCD Screening on HIV Testing Uptake and Engagement in HIV Care In Kisarawe, Tanzania

Hypertension | Diabetes Mellitus, Type 2 | Human Immunodeficiency Virus

Tanzania
Stanford University

Completed

Using Topical Sirolimus 2% for Patients With Epidermolysis Bullous Simplex (EBS) Study

Epidermolysis Bullosa Simplex | Epidermolysis Bullosa Simplex Kobner | Weber-Cockayne Syndrome

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Study of WR 6026 in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in HIV-Infected Patients

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
University of Hawaii
Tobira Therapeutics, Inc.

Completed

Effect of Cenicriviroc on HIV Neurocognitive Impairment

AIDS Dementia Complex | Human Immunodeficiency Virus | HIV-1-Associated Cognitive Motor Complex

United States
Walter K. Kraft
Merck Sharp & Dohme LLC

Completed

Doravirine, Rifapentine and Isoniazid Interaction (DORIIS)

Latent Tuberculosis | Human Immunodeficiency Virus | Drug Interaction Potentiation | Rifamycins Causing Adverse Effects in Therapeutic Use

United States
Massachusetts General Hospital
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Tesamorelin Effects on Liver Fat and Histology in HIV

Nonalcoholic Steatohepatitis (NASH) | Human Immunodeficiency Virus (HIV) | Nonalcoholic Fatty Liver Disease (NAFLD)

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Epacadostat and Pembrolizumab in Treating Participants With Advanced Pancreatic Cancer

Pancreatic Ductal Adenocarcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Homologous Recombination Deficiency | Stage IIA Pancreatic Cancer AJCC v8 | Stage IIB Pancreatic Cancer AJCC v8 | ATM Gene Mutation | Deleterious BRCA1 Gene... and other conditions
Fundação de Medicina Tropical Dr. Heitor Vieira...

Unknown

RIPE vs RIPE Plus N-acetylcysteine in Patients With HIV/TB Co-infection (RIPENACTB)

HIV/AIDS | Tuberculosis, Pulmonary

Brazil
Ferring Pharmaceuticals

Terminated

Study to Assess Long-term Effectiveness of Zomacton® and Treatment Adherence in Patients With Growth Hormone Deficiency or Ullrich-Turner Syndrome (RAZANT)

Growth Disorders

Germany
University Health Network, Toronto
CIHR Canadian HIV Trials Network

Completed

Can Valacyclovir Delay the Need for Initiation of Human Immunodeficiency Virus (HIV) Treatment in HIV-infected Individuals? (VALIDATE)

HIV Infections | HIV Infection | Herpes Simplex Type II

Canada, United Kingdom, Argentina, Brazil
National Taiwan University Hospital

Completed

Generic VEL/SOF With or Without RBV for HIV/HCV Coinfected Patients

Human Immunodeficiency Virus | Hepatitis C Virus Infection, Response to Therapy of

Taiwan
Salena Killion
Michael J. Fox Foundation for Parkinson's Research

Unknown

Using Heavy Water to Study Cell Dynamics in Parkinson's Disease

HIV Infections | Parkinson's Disease

United States
Merck KGaA, Darmstadt, Germany

Completed

Long Term Follow up Study of Predictive Markers in GHD and TS Children (PREDICT LT FUP)

Growth Hormon Deficiency | Turner Syndrome in Pre-pubertal Children
Abbott

Completed

A Comparison of Two Types of Injected Nutritional Supplements in Patients With AIDS and Pneumocystis Carinii Pneumonia (PCP)

HIV Infections

United States
Danish HIV Research Group
Odense University Hospital; Aarhus University Hospital; Rigshospitalet, Denmark; Hvidovre University Hospital

Completed

Switching From Zidovudine to an NNRTI or Lopinavir/Ritonavir in Patients Treated With Zidovudine/ Lamivudine/Abacavir.

HIV | Hypercholesterolemia | Lipoatrophy | HIV Associated Lipodystrophy Syndrome.

Denmark
National Center for Research Resources (NCRR)
University of California, San Diego

Completed

Evaluation of Fanconi Syndrome and Cystinosis

Fanconi Syndrome | Cystinosis
Glaxo Wellcome

Completed

A Comparison of Atovaquone and Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia in HIV-Infected Patients Who Cannot Take TMP/SMX

HIV Infections | Pneumonia, Pneumocystis Carinii

United States
Liposome

Completed

Safety and Efficacy of Amphotericin B Lipid Complex in the Treatment of Cryptococcal Meningitis in Patients With the Acquired Immunodeficiency Syndrome

HIV Infections | Meningitis, Cryptococcal

United States
H. Lee Moffitt Cancer Center and Research Institute

Recruiting

The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics

Lynch Syndrome | Pancreatic Ductal Adenocarcinoma | Chronic Pancreatitis | Pancreatic Cyst | Ataxia Telangiectasia | FAP | Peutz-Jeghers Syndrome | PALB2 Gene Mutation | BRCA Mutation | Fatty Pancreas | Genetic Pancreatic Cancer | Genetic Pancreatitis | Familial Atypical Multiple Mole-Melanoma

United States
University of Florida
Live Like Bella Pediatric Cancer Research

Completed

Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation

Common Variable Immunodeficiency | Severe Combined Immunodeficiency | Sickle Cell Disease | Hurler Syndrome | Chronic Granulomatous Disease | Thalassemia | Wiskott-Aldrich Syndrome | Adrenoleukodystrophy | X-linked Lymphoproliferative Disease | Diamond Blackfan Anemia | Bone Marrow Failure Syndrome | Hemophagocytic... and other conditions

United States
Emory University
Georgia Center for Oncology Research & Education

Not yet recruiting

Use of ACU-D1 in HPV Associated Vulvar and Perianal Lesions in People With HIV

Human Immunodeficiency Virus | Human Papilloma Virus | Anal Intraepithelial Neoplasia | High-Grade Squamous Intraepithelial Lesions

United States
Yale University
National Institute of Mental Health (NIMH); National Institutes of Health (NIH)

Recruiting

SV2A & TSPO PET Imaging Measures to Reveal Mechanisms of HIV Neuropathogenesis During Antiretroviral Therapy (ART)

Healthy | HIV Dementia | HIV Associated Neurocognitive Disorder | HIV Encephalitis

United States
The Second Affiliated Hospital of Chongqing Medical...

Recruiting

Safety and Immune Response of COVID-19 Vaccination in Patients With HIV Infection

HIV Infections | Covid19

China
Genzyme, a Sanofi Company

Recruiting

Pompe Pregnancy Sub-Registry

Pompe Disease (Late-onset) | Glycogen Storage Disease Type II (GSD-II) | Glycogenesis 2 Acid Maltase Deficiency

Croatia, United States, Italy, Belgium, Czechia
M.D. Anderson Cancer Center

Recruiting

Registry for Women Who Are At Risk Or May Have Lynch Syndrome

Lynch Syndrome | Hereditary Nonpolyposis Colorectal Cancer

United States
Yale University
National Institute on Drug Abuse (NIDA); University of Malaya

Completed

Intervention of HIV, Drug Use and the Criminal Justice System in Malaysia (Harapan)

Acquired Immunodeficiency Syndrome | Human Immunodeficiency Virus | Opiate Addiction | Drug Dependence
Columbia University
National Institute of Mental Health (NIMH); Yale University

Active, not recruiting

Building Mobile HIV Prevention and Mental Health Support in Low-resource Settings

Depression, Anxiety | Human Immunodeficiency Virus | Risk Reduction | Alcohol Abuse | Behavior, Sex

Romania
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Cycling in Preventing Colorectal Cancer in Participants With Lynch Syndrome

High-Frequency Microsatellite Instability | Mismatch Repair Gene Mutation | Mutation-Negative Lynch Syndrome | Mutation-Positive Lynch Syndrome

United States

Clinical Trials on Complement Deficiency

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Trinidad & Tobago

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations