Clinical Trials on Congenital Cataract in South Africa

Total 409 results

Medtronic Endovascular

Completed

IN.PACT™ AV Access IDE Study

Fistula | Arteriovenous Fistula | Arteriovenous Fistula Stenosis | Arteriovenous Fistula Occlusion

New Zealand, United States, Japan
National Heart, Lung, and Blood Institute (NHLBI)
National Institutes of Health (NIH)

Completed

Pediatric Hydroxyurea Phase III Clinical Trial (BABY HUG) Follow-up Observational Study II Protocol (BABY HUG)

Sickle Cell Anemia

United States
AstraZeneca

Completed

A Study to Assess the Effect of Ticagrelor in Reducing the Number of Days With Pain in Patients With Sickle Cell Disease (Hestia2)

Sickle Cell Disease

United States, Italy, France, United Kingdom, Turkey, Egypt, Lebanon, Kenya
Zynerba Pharmaceuticals, Inc.

Recruiting

Clinical Study of Cannabidiol in Children, Adolescents, and Young Adults With Fragile X Syndrome (RECONNECT)

Fragile X Syndrome

United States, Australia, United Kingdom, Ireland
Sanford Health
National Ataxia Foundation; Beyond Batten Disease Foundation; Pitt Hopkins Research... and other collaborators

Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (CoRDS)

Mitochondrial Diseases | Retinitis Pigmentosa | Myasthenia Gravis | Eosinophilic Gastroenteritis | Multiple System Atrophy | Leiomyosarcoma | Leukodystrophy | Anal Fistula | Spinocerebellar Ataxia Type 3 | Friedreich Ataxia | Kennedy Disease | Lyme Disease | Hemophagocytic Lymphohistiocytosis | Spinocerebellar Ataxia... and other conditions

United States, Australia
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Hydroxyurea to Prevent Organ Damage in Children With Sickle Cell Anemia

Hematologic Diseases | Anemia, Sickle Cell

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Long-Term Effects of Hydroxyurea in Children With Sickle Cell Anemia (The BABY HUG Follow-up Study)

Anemia, Sickle Cell

United States
ReCode Therapeutics

Recruiting

Study Evaluating the Safety and Tolerability of RCT1100 in Healthy and PCD Subjects

Primary Ciliary Dyskinesia

United Kingdom, United States, Australia, New Zealand
Scioderm, Inc.
Amicus Therapeutics

Completed

ESSENCE Study: Efficacy and Safety of SD-101 Cream in Participants With Epidermolysis Bullosa

Epidermolysis Bullosa

Italy, Spain, Serbia, United States, Australia, Netherlands, Austria, Germany, Israel, Lithuania, France, United Kingdom, Poland
Vifor (International) Inc.
Fortrea

Completed

Study to Assess Efficacy and Safety of VIT-2763 (Vamifeport) in Subjects With Sickle Cell Disease (ViSionSerenity)

Sickle Cell Disease

United States, France, Greece, Lebanon, United Kingdom
bluebird bio

Enrolling by invitation

Long-term Follow-up of Subjects With Sickle Cell Disease Treated With Ex Vivo Gene Therapy

Sickle Cell Disease

United States, France
W.L.Gore & Associates

Recruiting

GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study (REDUCE PAS)

Stroke | PFO - Patent Foramen Ovale

United States
bluebird bio

Active, not recruiting

Long-term Follow-up of Subjects With Transfusion-Dependent β-Thalassemia (TDT) Treated With Ex Vivo Gene Therapy

Transfusion-dependent Beta-Thalassemia

United States, France, United Kingdom, Australia, Thailand, Italy, Germany, Greece
University of Alabama at Birmingham
Medtronic; The Children's Tumor Foundation

Terminated

A Study of INFUSE Bone Graft (BMP-2) in the Treatment of Tibial Pseudarthrosis in Neurofibromatosis Type 1 (NF1) (NF107-BMP2)

NF1 | Congenital Pseudarthrosis of Tibia

United States, Australia
Amryt Research Limited

Completed

Phase III Efficacy and Safety Study of Oleogel-S10 in Epidermolysis Bullosa (EASE)

Epidermolysis Bullosa

United States, Spain, Israel, Australia, France, Denmark, Switzerland, Italy, Hong Kong, Argentina, Austria, Brazil, Chile, Colombia, Czechia, Georgia, Germany, Greece, Hungary, Ireland, Romania, Russian Federation, Serbia, Singapore, U... and more
ApoPharma

Terminated

Long-term Safety and Efficacy of Ferriprox® in Iron Overloaded Patients With Sickle Cell Disease or Other Anemias

Iron Overload | Sickle Cell Disease | Other Anemias

United States, United Kingdom, Egypt, Canada, Saudi Arabia
Sequenom, Inc.
PRA Health Sciences

Completed

Noninvasive Screening for Fetal Aneuploidy: A New Maternal Plasma Marker

Pregnancy | Down Syndrome | Aneuploidy | Edwards Syndrome

United States, France
Spruce Biosciences

Active, not recruiting

A Ph2b to Evaluate Tildacerfont in the Reduction of Glucocorticoid Steroid Doses in Adult CAH

Congenital Adrenal Hyperplasia

United States, Australia, Brazil, Estonia, Germany, Korea, Republic of, Latvia, Lithuania, Poland, Romania, Spain, Sweden, Turkey, Canada, Italy, United Kingdom
Zynerba Pharmaceuticals, Inc.

Completed

Clinical Study Of caNNabidiol in childrEn and adolesCenTs With Fragile X (CONNECT-FX) (CONNECT-FX)

Fragile X Syndrome

United States, New Zealand, Australia
Seoul National University Hospital
Asan Medical Center; Johannes Gutenberg University Mainz; Gyeongsang National... and other collaborators

Active, not recruiting

CoHOrt of Cerebral CavernOus maLformATion: multicEnter Prospective Observational Study (CHOCOOATE)

Intracerebral Hemorrhage | Cerebral Cavernous Malformation

Korea, Republic of
Celgene
Acceleron Pharma Inc. (a wholly owned subsidiary of Merck Sharp and Dohme...

Completed

An Efficacy and Safety Study of Luspatercept (ACE-536) Versus Placebo in Adults Who Require Regular Red Blood Cell Transfusions Due to Beta (β) Thalassemia (BELIEVE)

Beta-Thalassemia | Erythrocyte Transfusion

United States, Israel, Australia, Turkey, Taiwan, Malaysia, United Kingdom, Canada, Thailand, France, Lebanon, Italy, Bulgaria, Greece, Tunisia
rEVO Biologics

Completed

Assess Incidence of Deep Vein Thrombosis(DVT)Following Administration of Recombinant Human Antithrombin (rhAT) to Hereditary Antithrombin(AT) Deficient Patients in High Risk Situations. (rhAT)

Antithrombin Deficiency, Congenital

France, United Kingdom, Germany, United States, Sweden, Italy
QOL Medical, LLC

Recruiting

7-Day Trial of Sucraid for Alleviating CSID Symptoms in Subjects With Low, Moderate, and Normal Sucrase Levels

Congenital Sucrase-Isomaltase Deficiency | CSID | Sucrase Isomaltase Deficiency

United States
Novo Nordisk A/S

Available

Compassionate Use of Concizumab if You Have Haemophilia

Congenital Haemophilia

United States, Bulgaria, Sweden
Sequenom, Inc.

Recruiting

Specimen Collection From Pregnant Women at Increased Risk for Fetal Aneuploidy

Down Syndrome | Fetal Aneuploidy

United States, Canada
Novo Nordisk A/S

Completed

Efficacy and Safety of NNC-0156-0000-0009 During Surgical Procedures in Subjects With Haemophilia B (paradigm™ 3)

Congenital Bleeding Disorder | Haemophilia B

United States, Netherlands, Austria, Spain, Germany, Macedonia, The Former Yugoslav Republic of, Taiwan, United Kingdom, Italy, Malaysia, Thailand, France, Greece, Turkey, Japan, South Africa, Romania
Zimmer Biomet

Active, not recruiting

Persona Ti-Nidium Post-Market Clinical Follow-up (TKA)

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Patellofemoral Osteoarthritis | Traumatic Arthritis | Varus Deformity | Valgus Deformity | Knee Pain Chronic | Polyarthritis | Flexion Deformity of the Knee

United States
VentureMed Group Inc.

Completed

FLEX Arteriovenous Access Registry

Peripheral Artery Disease | Arteriovenous Fistula Stenosis | Arteriovenous Graft Stenosis

United States
Editas Medicine, Inc.

Recruiting

A Study Evaluating the Safety and Efficacy of EDIT-301 in Participants With Severe Sickle Cell Disease (RUBY)

Sickle Cell Disease | Hemoglobinopathies

United States, Canada
Yale University
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Exercise in Genetic Cardiovascular Conditions (LIVE-HCM/LQT)

Hypertrophic Cardiomyopathy | Long QT Syndrome

United States, United Kingdom, Canada, Australia, New Zealand
C. R. Bard

Completed

Study Comparing Lutonix AV Drug Coated Balloon vs Standard Balloon for Treatment of Dysfunctional AV Fistulae

Arteriovenous Fistula

United States
Mark Gladwin

Completed

A Multi-Center Study of Riociguat in Patients With Sickle Cell Diseases

Sickle Cell Disease

United States
Spruce Biosciences

Active, not recruiting

A Ph2b to Evaluate Clinical Efficacy and Safety of Tildacerfont in Adult CAH

Congenital Adrenal Hyperplasia

United States, Australia, Brazil, Canada, Denmark, Estonia, Germany, Ireland, Italy, Korea, Republic of, Latvia, Lithuania, Netherlands, Poland, Romania, Spain, Sweden, Switzerland, Turkey, United Kingdom
Medical College of Wisconsin
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Evaluating the Safety and Effectiveness of Bone Marrow Transplants in Children With Sickle Cell Disease (BMT CTN 0601) (SCURT)

Sickle Cell Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cord Blood Transplantation for Sickle Cell Anemia and Thalassemia

Hematologic Diseases | Anemia, Sickle Cell | Beta-Thalassemia | Hematopoietic Stem Cell Transplantation

United States, Canada
Novo Nordisk A/S

Completed

Efficacy and Safety of NNC 0078-0000-0007 in Patients With Congenital Haemophilia and Inhibitors (adept™2)

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

Taiwan, United Kingdom, Thailand, Serbia, Croatia, Italy, Poland, Romania, Hungary, Malaysia, United States, Austria, Brazil, Greece, Japan, Puerto Rico, Russian Federation, South Africa, Turkey
Novo Nordisk A/S

Completed

Efficacy of NovoSeven® in Bleeding Prophylaxis in Hemophilia

Congenital Bleeding Disorder | Haemophilia A With Inhibitors | Haemophilia B With Inhibitors

France, United States, Spain, Brazil, Philippines, South Africa, Poland, Turkey, Romania, Bulgaria, Russian Federation, Argentina
Novo Nordisk A/S

Completed

Safety and Efficacy of NNC-0156-0000-0009 in Haemophilia B Patients (paradigm™ 2)

Congenital Bleeding Disorder | Haemophilia B

United States, Netherlands, Germany, Macedonia, The Former Yugoslav Republic of, United Kingdom, Italy, Malaysia, Hungary, Thailand, France, Russian Federation, Turkey, Japan, South Africa, Canada
Emory University
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

STRIDE Biorepository

Anemia, Sickle Cell

United States
AMO Pharma Limited

Recruiting

Safety and Efficacy of Tideglusib in Congenital or Childhood Onset Myotonic Dystrophy (REACH CDM X)

Congenital Myotonic Dystrophy

United States, Canada, Australia, New Zealand
Pfizer
Pfizer

Recruiting

Oxbryta® Product Registry An Observational Study Designed to Evaluate the Effect of Oxbryta in Individuals With SCD (PROSPECT)

Sickle Cell Disease

United States
Natera, Inc.
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Terminated

Prenatal Non-invasive Aneuploidy Test Utilizing SNPs Trial (PreNATUS)

Aneuploidy | Trisomy 21 | Trisomy 18 | Trisomy 13

United States, Ireland, Canada, Italy, Korea, Republic of, Spain
UK Kidney Association

Recruiting

National Registry of Rare Kidney Diseases (RaDaR)

Vasculitis | AL Amyloidosis | Tuberous Sclerosis | Fabry Disease | Cystinuria | Focal Segmental Glomerulosclerosis | IgA Nephropathy | Bartter Syndrome | Pure Red Cell Aplasia | Membranous Nephropathy | Atypical Hemolytic Uremic Syndrome | Autosomal Dominant Polycystic Kidney Disease | Cystinosis | Nephronophthisis | BK Nephropathy and other conditions

United Kingdom
Medtronic

Recruiting

IN.PACT™ AV Access Post-Approval Study (PAS002)

Fistula | Arteriovenous Fistula | Arteriovenous Fistula Stenosis | Arteriovenous Fistula Occlusion

United States
Novo Nordisk A/S

Completed

Safety and Efficacy of NNC-0156-0000-0009 After Long-Term Exposure in Patients With Haemophilia B: An Extension to Trials NN7999-3747 and NN7999-3773 (paradigm™ 4)

Congenital Bleeding Disorder | Haemophilia B

United States, Netherlands, Austria, Spain, Germany, Macedonia, The Former Yugoslav Republic of, Taiwan, United Kingdom, Italy, Malaysia, Thailand, France, Greece, Russian Federation, Turkey, Japan, South Africa, Romania
Novartis Pharmaceuticals

Completed

A Study to Evaluate the Safety and Efficacy of Crizanlizumab in Sickle Cell Disease Related Priapism (SPARTAN)

Priapism

United States
Zynerba Pharmaceuticals, Inc.

Enrolling by invitation

Open Label Extension to Assess the Long-Term Safety and Tolerability of ZYN002 in Children and Adolescents With FXS

Fragile X Syndrome

United States, United Kingdom, New Zealand, Australia
AMO Pharma Limited

Completed

Efficacy and Safety of Tideglusib in Congenital Myotonic Dystrophy

Congenital Myotonic Dystrophy

United States, Canada, New Zealand, Australia, United Kingdom
Medical College of Wisconsin
National Heart, Lung, and Blood Institute (NHLBI); Dana-Farber Cancer Institute and other collaborators

Completed

Bone Marrow Transplantation vs Standard of Care in Patients With Severe Sickle Cell Disease (BMT CTN 1503) (STRIDE2)

Sickle Cell Disease

United States
Pfizer
Pfizer

Available

Expanded Access Protocol for Adults and Pediatric Patients With Sickle Cell Disease Who Have No Alternative Treatment Options

Sickle Cell Disease

United States, Brazil

Clinical Trials on Congenital Cataract in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Uzbekistan

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations