Clinical Trials on Congenital Hematological Disorder

Total 154691 results

Universidad de Sonora
Hospital Civil de Guadalajara; International Atomic Energy Agency; Centro de...

Recruiting

Body Composition and Nutritional Status in Pediatric Patients With Hematological Malignancies (HM)

Childhood Obesity | Childhood Cancer | Child Malnutrition

Mexico
University Health Network, Toronto

Completed

Safety Study Looking at the Use of a Natural Killer Cell Line Against Hematological Malignancies

Lymphoma | Leukemia | Myeloma | Hodgkin's Disease

Canada
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

A Study of TQB3820 in Patients With Hematological Malignancies

Hematological Malignancies

China
Tampere University Hospital
Helsinki University Central Hospital; Tampere University; University of Eastern... and other collaborators

Active, not recruiting

Tissue Microarray of Hematological Malignancies (HemaTMA)

Hematological Malignancies

Finland
University Hospital Freiburg

Completed

Assessing Immune Function in Young Patients With Cytopenia That Did Not Respond to Treatment

Myelodysplastic Syndromes | Fanconi Anemia | Dyskeratosis Congenita | Pearson Marrow-pancreas Syndrome | Shwachman-diamond Syndrome

Spain, Germany, Switzerland, Austria, Netherlands, Italy, Czech Republic, Belgium, Denmark, Ireland
Grete Andersen, MD

Completed

Relations Between Myotonia and Fitness

Congenital Myotonia

Denmark
Malaghan Institute of Medical Research

Recruiting

Continuous Temperature Monitoring for tHe Early Recognition of Febrile Neutropenia in Haematological MALignancies (THERMAL)

Lymphoma | Leukemia | Myeloma | Temperature Change, Body | Haematological Malignancy

New Zealand
University of California, San Francisco
National Cancer Institute (NCI)

Completed

Donor Stem Cell Transplant in Treating Young Patients With Myelodysplastic Syndrome, Leukemia, Bone Marrow Failure Syndrome, or Severe Immunodeficiency Disease

Myelodysplastic Syndromes | Leukemia | Congenital Amegakaryocytic Thrombocytopenia | Severe Congenital Neutropenia

United States
Children's Hospital of Philadelphia
Masimo Corporation

Recruiting

International Study of Cerebral Oxygenation and Electrical Activity During Major Neonatal Surgery

Congenital Disorders | Cerebral Desaturation | Neonatal Surgery

United States, United Kingdom, China, Australia, France, India, Brazil
GlaxoSmithKline

Completed

Bupropion & Cardio Birth Defect (Slone)

Depressive Disorder
Sohag University

Not yet recruiting

Prognostic Value of "CD200" in Hematological Malignancies. Hematological Malignancies Comprise a Group of Malignant Clonal Disorders Arising From the Hematopoietic Tissues , Including Leukemia , Multiple Myeloma , and They Have a High Morbidity and Mortality

Hematological Malignancies
Incuron

Terminated

Study of IV CBL0137 in Previously Treated Hematological Subjects

Hematological Malignancies

United States
Ankara University
The Scientific and Technological Research Council of Turkey

Completed

Mesenchymal Stem Cell Infusion in Haploidentical Hematopoietic Stem Cell Transplantation in Patients With Hematological Malignancies

Hematopoietic Stem Cell Transplantation

Turkey
Gemin X

Completed

Safety and Efficacy of Obatoclax Mesylate (GX15-070MS) for the Treatment of Hematological Malignancies

Hematological Malignancies

United States, Canada
M.D. Anderson Cancer Center
ImmunoGen, Inc.

Completed

An Open-label Phase II Study of Lorvotuzumab Mertansine

Leukemia

United States
Kai Lin Xu; Jun Nian Zheng
iCarTAB BioMed Inc.

Unknown

CD22 Targeting CAR-T Therapy Against B Cell Hematological Malignancies

Recurrent or Refractory B Cell Malignancy

China
The Affiliated People's Hospital of Ningbo University

Recruiting

Etoposide+Cytarabine+PEG-rhG-CSF as First Line Mobilization Regimen of Hematopoietic Stem Cells in Patients With Hematological Malignancies

Lymphoma | Multiple Myeloma

China
Janssen Research & Development, LLC

Recruiting

Dose Escalation Study of Teclistamab, a Humanized BCMA*CD3 Bispecific Antibody, in Participants With Relapsed or Refractory Multiple Myeloma (MajesTEC-1)

Hematological Malignancies

United States, Netherlands, Spain, France, Sweden
Janssen Research & Development, LLC

Recruiting

Dose Escalation Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma (MonumenTAL-1)

Hematological Malignancies

United States, Netherlands, Spain, Belgium
University of Arkansas

Withdrawn

UARK 2006-28 Human Cord Blood Transplantation in Advanced Hematological Malignancies

Multiple Myeloma

United States
Lund University
Rigshospitalet, Denmark; University of Iceland; Skane University Hospital; Arba...

Enrolling by invitation

eHealth as an Aid for Facilitating and Supporting Self-management in Families With Long-term Childhood Illness (eChildHealth)

Preterm Birth | Congenital Heart Disease | Pediatric Cancer | Hirschsprung Disease | Nutrition Disorder, Child | Congenital Malformation

Denmark, Sweden
Robert Krause, MD

Completed

Prospective Clinical Evaluation of Beta-D-Glucan Assay in Blood and BAL

Invasive Fungal Infection | Hematological Malignancy | Receipt of Solid Organ Transplant

Austria
Luzerner Kantonsspital

Recruiting

Prevalence of FID and QoL in Patients With Oncological and With Haematological Malignancies

Functional Iron Deficiency

Switzerland
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Sun Yat-sen University; Shanghai Zhongshan... and other collaborators

Unknown

Peripheral Blood Stem Cell Combined With Mesenchymal Stem Cells for Treatment of Poor Graft Function

Hematological Diseases | Stem Cell Transplantation, Hematopoietic | Poor Graft Function

China
University Hospital, Montpellier

Completed

Transition From Adolescents to Adulthood for Patients With Congenital Heart Diseases

Congenital Heart Diseases

France
Shriners Hospitals for Children

Completed

Botox Injection for Lower Extremity Lengthening and Deformity Correction Surgery (BOLLD)

Lower Extremity Deformities, Congenital | Unequal Length of Limbs; Congenital

Canada, United States
Oslo University Hospital

Unknown

Outcomes in Patients and Their Closest Relatives Treated for Congenital Heart Disease With Catheter Based or Surgical Techniques (MEQC)

Congenital Heart Defects

Norway
National Taiwan University Hospital

Completed

Exercise Training in Children With Congenital Heart Defect

Congenital Heart Disease

Taiwan
The Children's Hospital of Zhejiang University...
Leman Biotech Co., Ltd

Recruiting

Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of Relapsed and/or Refractory CD19-positive B Cell Hematological Malignancies Clinical Research

Acute Lymphoblastic Leukemia | Non-hodgkin Lymphoma

China
Anhui Provincial Hospital
Leman Biotech Co., Ltd

Recruiting

Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of Relapsed and/or Refractory CD19-positive B Cell Hematological Malignancies Clinical Research

Acute Lymphoblastic Leukemia | Non-hodgkin Lymphoma

China
Merck Sharp & Dohme LLC

Active, not recruiting

A Clinical Study of Nemtabrutinib in Japanese Participants With Hematological Malignancies (MK-1026-002)

Mature B-cell Neoplasms

Japan
Leiden University Medical Center

Enrolling by invitation

Evaluating Prenatal Exome Sequencing Study (EPES)

Genetic Diseases, Inborn | Mendelian Disorders | Congenital Anomalies

Netherlands
Novo Nordisk A/S

Completed

Haemophilia Patients With Inhibitors Being Treated for Acute Joint Bleeds

Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

United States, Spain, Taiwan, Turkey, Poland, Croatia, Italy, Malaysia, Brazil, United Kingdom, Hungary, Israel, Thailand, Japan, South Africa, Canada, France, Argentina
Novo Nordisk A/S

Completed

Pharmacokinetics of Single Bolus Dose of NovoSeven® in Paediatric and Adult Patients With Haemophilia A or B in a Non- Bleeding State

Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

Spain, Italy, Greece, Germany, United Kingdom
Novo Nordisk A/S

Completed

Post-marketing Safety Surveillance of NovoSeven® in Patients With Haemophilia and Inhibitors by Means of the UK Haemophilia Database

Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

United Kingdom
Novo Nordisk A/S

Completed

Intra-subject Variability Following Administrations of Activated Recombinant Human Factor VII in Haemophilia Patients in a Non-bleeding State

Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

France, Israel, Germany
Novo Nordisk A/S

Completed

Observational Study Describing the Usual Clinical Practice Use of NovoSeven® in the Home Treatment of Joint Bleeds in Patients With Haemophilia A or B and Inhibitors

Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

Morocco, United Arab Emirates, Algeria, Oman, Saudi Arabia
Novo Nordisk A/S

Completed

Investigating Safety and Pharmacokinetics of 2 Different Single Doses of NNC128-0000-2011 in Haemophilia A or B Patients

Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

Spain, Germany, Japan
Novo Nordisk A/S

Completed

Safety and Mode of Action of a Single Dose and Multiple Doses of Long Acting Activated Recombinant Human Factor VII in Patients With Haemophilia A and B

Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

Spain
Novo Nordisk A/S

Completed

Investigating Safety and Pharmacokinetics of NNC 0128-0000-2011 Compared to NNC 0128-0000-2021 in Healthy Male Subjects

Congenital Bleeding Disorder | Haemophilia A | Haemophilia B

United Kingdom
Emory University

Completed

Bone Marrow Transplant With Abatacept for Non-Malignant Diseases

Sickle Cell Disease | Fanconi Anemia | Hurler Syndrome | Chronic Granulomatous Disease | Severe Congenital Neutropenia | Hemophagocytic Lymphohistiocytosis | Wiskott-Aldrich Syndrome | Diamond-Blackfan Anemia | Severe Aplastic Anemia | Glanzmann Thrombasthenia | Shwachman-Diamond Syndrome | Thalassemia Major | Leukocyte... and other conditions

United States
Assiut University

Unknown

/Autism Spectrum Disorder(ASD)Hearing Abnormalities Study

Autism Spectrum Disorder
St. Jude Children's Research Hospital

Recruiting

A Phase II Pediatric Study of a Graft-VS.-Host Disease (GVHD) Prophylaxis Regimen With no Calcineurin Inhibitors After Day +60 Post First Allogeneic Hematopoietic Cell Transplant for Hematological Malignancies

Hematologic Malignancy | Myeloid Malignancy

United States
Takeda

Active, not recruiting

A Study of TAK-662 for Japanese Patients With Congenital Protein C Deficiency

Congenital Protein C Deficiency

Japan
National Cardiovascular Center Harapan Kita Hospital...
Danone Institute International

Completed

The Effect of High-Calorie Formula on Nutritional and Clinical Outcomes Among Infants After Congenital Heart Surgery

Malnutrition, Child | Congenital Heart Disease in Children

Indonesia
Indiana Hemophilia &Thrombosis Center, Inc.
Genentech, Inc.

Recruiting

Hemlibra in Mild Hemophilia A

Factor VIII Deficiency, Congenital

United States
Zhejiang University
Yake Biotechnology Ltd.

Recruiting

Clinical Trial for the Safety and Efficacy of Anti-CD7 CAR-T Cell Therapy for Patients With Relapsed or Refractory CD7 Positive Hematological Malignancy

CD7+ Acute Leukemia | CD7+ Lymphoma

China
CSL Behring

Completed

Pharmacokinetic, Efficacy, and Safety Study of Recombinant Factor VIII Single Chain (rVIII-SingleChain) in Children With Severe Hemophilia A

Congenital Hemophilia A

United States, Austria, Germany, Malaysia, Netherlands, Philippines, Ukraine, Romania, Spain, Australia, France, Georgia, Italy, Lebanon, Poland, Portugal, Switzerland, Thailand, Turkey
Hospices Civils de Lyon

Unknown

Observatory of the Prescription of Erythropoietin as Treatment of Anemia Induced by Chemotherapy or Allograft Conditioning Among the Patients With a Haematological Malignancy (EPREX/LAM-ALLO)

Acute Myeloid Leukemia | Anemia

France
Novo Nordisk A/S

Completed

Safety and Efficacy of Nonacog Beta Pegol (N9-GP) in Previously Untreated Patients With Haemophilia B (paradigm™6)

Congenital Bleeding Disorder | Haemophilia B

Spain, United Kingdom, Australia, Taiwan, France, Malaysia, United States, Austria, Canada, Israel, Japan, Thailand, Algeria, Argentina

Clinical Trials on Congenital Hematological Disorder

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