Clinical Trials on Connective Tissue Diseases in United Kingdom

Total 146902 results

Imperial College London
InSightec-TxSonics

Completed

Efficacy Study of Magnetic Resonance (MR) Guided Focused Ultrasound in the Treatment of Large Fibroids

Uterine Fibroids

United Kingdom
University of Edinburgh
NHS Lothian

Completed

Novel MRI Strategies as a Non-invasive Biomarker in Women With Uterine Fibroids

Leiomyoma | Fibroid

United Kingdom
Imperial College London
InSightec

Withdrawn

Safety Trial of Magnetic Resonance (MR) Guided Focused Ultrasound Surgery (FUS) in Women With Uterine Fibroids Wishing to Pursue Pregnancy in the Future

Pregnancy | Uterine Fibroids

United Kingdom
Bayer

Terminated

Mode of Action Study of Vilaprisan and Ulipristal Acetate in Patients With Uterine Fibroids for Whom Surgery is Planned

Leiomyoma

United Kingdom
University of Stirling

Completed

Groups for Specific vs Mixed Diagnosis Patients of Chronic Conditions

Cardiovascular Diseases | Skin Diseases | Diabetes | Rheumatic Diseases | Mental Health Issue

United Kingdom
King's College Hospital NHS Trust
Hemab

Recruiting

Are Uterine Fibroids Pro-thrombotic?

Thrombosis | Leiomyoma, Uterine

United Kingdom
University Hospital Southampton NHS Foundation...
Vascular Solutions LLC

Completed

Uterine Fibroid Embolization (UFE) for Symptomatic Fibroids: Comparison of Gel-Bead to Commonly Used Embolic Agents.

Uterine Fibroid | Embolization | Symptoms

United Kingdom
Liverpool University Hospitals NHS Foundation Trust

Withdrawn

BOND Study: the Benefit Of Night Splinting in Dupuytrens' (BOND)

Dupuytren Contracture

United Kingdom
Newcastle University
Newcastle-upon-Tyne Hospitals NHS Trust; Cumbria, Northumberland Tyne and Wear...

Completed

Reducing Uncertainty Distress in Long Term Health Conditions

Rheumatic Diseases

United Kingdom
Royal Marsden NHS Foundation Trust
Merck Sharp & Dohme LLC

Active, not recruiting

Pembrolizumab and Gemcitabine Chemotherapy in Leiomyosarcoma and Undifferentiated Pleomorphic Sarcoma (GEMMK)

Sarcoma

United Kingdom
BioPoly LLC

Recruiting

BioPoly® RS Partial Resurfacing Patella Registry Study

Cartilage Disease

United Kingdom
InSightec

Withdrawn

Study to Evaluate the Safety and Effectiveness of MRgFUS Compared With Myomectomy for the Treatment of Uterine Fibroids

Bleeding | Pelvic Pain | Uterine Fibroids

United Kingdom
University College, London
University College London Hospitals

Unknown

The Role of Lipids in Immune Cell Function in SLE Patients

Lupus Erythematosus, Systemic

United Kingdom
GlaxoSmithKline

Completed

A Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of GSK2330811 in Healthy Subjects

Scleroderma, Systemic

United Kingdom
Theraclion
King's College London

Completed

Feasibility Study Assessing the Treatment of Fibroadenomata With a Circumferential Sonication Treatment With HIFU

Breast Fibroadenoma

United Kingdom
University of Oxford
Wellcome Trust; Department of Health, United Kingdom; 180 Therapeutics LP

Completed

Repurposing Anti-TNF for Treating Dupuytren's Disease (RIDD)

Dupuytren's Disease

United Kingdom, Netherlands
Endo Pharmaceuticals

Completed

An Open-label Study to Assess the Safety and Effectiveness of AA4500 in Combination With the ErecAid® Esteem® Manual Vacuum Therapy System in Treating Men With Peyronie's Disease

Peyronie's Disease

United Kingdom
University College, London
Richard Scowcroft Foundation

Terminated

Will Glucarpidase After Methotrexate Treatment for Bone Sarcoma Lead to Fewer Side Effects and Reduce Chemotherapy Delays?

Osteosarcoma | Spindle Cell Sarcoma of Bone

United Kingdom
Glasgow Caledonian University

Recruiting

Characteristics of Pain in Women With Lipoedema

Lipedema

United Kingdom
King's College London

Completed

Does Size Matter: A Single Case Experimental Design of Limiting the Depth of Penetration During Intercourse

Peyronie Disease

United Kingdom
GlaxoSmithKline

Not yet recruiting

A First Time in Human Study to Evaluate the Safety and Tolerability of GSK3996401 Following Dosing With GSK4347859 in Healthy Participants

Systemic Lupus Erythematosus

United Kingdom
Autolus Limited

Recruiting

A Study of CD19 Targeted CAR T Cell Therapy in Patients With Severe, Refractory Systemic Lupus Erythematosus (SLE) (CARLYSE)

Systemic Lupus Erythematosus

United Kingdom
UCB Biopharma S.P.R.L.
Pharmaceutical Research Associates; Richmond Pharmacology Limited; Eurofins; ACM... and other collaborators

Completed

Study to Compare Properties of Epratuzumab When Given as an Injection Under the Skin or Directly Into the Blood

Systemic Lupus Erythematosus

United Kingdom
Oxford University Hospitals NHS Trust
Surgical Intervention Trials Unit (trial oversight); NIHR Direct Delivery Team... and other collaborators

Recruiting

HIFU Ablation of Soft Tissue Sarcoma (SarcAblate)

Soft Tissue Sarcoma | Desmoid; Abdominal

United Kingdom
AstraZeneca

Completed

The Biological Activity of Cediranib (AZD2171) in Gastro-Intestinal Stromal Tumours(GIST).

Gastrointestinal Stromal Tumors | Soft Tissue Sarcomas

United Kingdom
GlaxoSmithKline

Terminated

Study to Evaluate Fractional Collagen Synthesis Within Keloid Scars and Identify Biomarkers of Keloid Scars

Fibrosis

United Kingdom
GlaxoSmithKline

Terminated

First-time-in-Human (FTIH) Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single (in Both Fed and Fasted States) or Repeat Doses of GSK3358699

Arthritis, Rheumatoid

United Kingdom
University Hospitals Bristol and Weston NHS Foundation...
Public Health England; University of Bristol

Completed

Adjunctive Clindamycin for Cellulitis: C4C Trial. (C4C)

Cellulitis

United Kingdom
GlaxoSmithKline

Completed

Study Of 90mg Of GW274150 In Subjects Over 50 Years, Who Have Rheumatoid Arthritis (RA)

Arthritis, Rheumatoid

United Kingdom
GlaxoSmithKline

Terminated

Phase 1 Dose Escalating Study to Assess Safety, Tolerability, Food Effect and PK of CHR-5154 in Healthy Male Volunteers

Arthritis, Rheumatoid

United Kingdom
University Hospital Muenster
Medical Research Council

Unknown

Combination Chemotherapy Plus Surgery and Radiation Therapy in Treating Patients With Ewing's Sarcoma

Sarcoma

United Kingdom
NHS Greater Glasgow and Clyde
University of Michigan

Completed

Exploiting Leading Edge 7T MRI Brain Imaging to Decipher Olumiant's Mode of Analgesic Action in Rheumatoid Arthritis (SOAR)

Rheumatoid Arthritis

United Kingdom
University of Dundee

Completed

Rosuvastatin in Rheumatoid Arthritis (RORA) (RORA)

Rheumatoid Arthritis

United Kingdom
University of Oxford
UCB Pharma

Completed

Pictorial Representation of Illness and Self Measure (PRISM)

Rheumatoid Arthritis

United Kingdom
AstraZeneca

Completed

AZD5672 Bioavailability Study in Healthy Male and Female Subjects

Rheumatoid Arthritis

United Kingdom
Imperial College London
Merck Sharp & Dohme LLC

Terminated

A Study to Evaluate the RNA Signature of Rheumatoid Arthritis From Synovium and Whole Blood

Rheumatoid Arthritis

United Kingdom
University of Ulster

Completed

RADAR1- Trial of a New Blood Sample Method (Remote Arthritis Disease Activity MonitoR) (RADAR)

Rheumatoid Arthritis

United Kingdom
AstraZeneca
Quintiles, Inc.

Completed

A Study to Investigate the Potential for AZD5672 to Affect the Electrical Conduction Pathways in the Heart

Rheumatoid Arthritis

United Kingdom
University of Manchester

Completed

Light Treatment for Scleroderma Finger Ulcers (DULight)

Ulcer | Scleroderma, Systemic

United Kingdom
University of Oxford
Arthritis Research UK

Unknown

Interferon-lambda: Novel Biologics for Controlling Neutrophil-mediated Pathology in Rheumatic Diseases? (ILAND)

Arthritis | Vasculitis

United Kingdom
Sheffield Children's NHS Foundation Trust
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Psychosocial Outcomes and Transition Readiness in JIA

Juvenile Idiopathic Arthritis

United Kingdom
Institute of Child Health

Unknown

PRINTO (the Paediatric Rheumatology International Trials Organisation)

Juvenile Idiopathic Arthritis

United Kingdom
University of Oxford
UCB Pharma

Completed

Biomarker Signature and Musculoskeletal Ultrasound Profile in Rheumatoid Arthritis Patients (BMUS)

Rheumatoid Arthritis

United Kingdom
University of Ulster
Western Health and Social Care Trust

Completed

A Comparison of Two Electronic Gloves in the Measurement of Joint Movement in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

United Kingdom
Imperial College London
Medical Research Council

Completed

Ultrasonography as a Biomarker in Early Rheumatoid Arthritis

Rheumatoid Arthritis

United Kingdom
Hoffmann-La Roche

Completed

A Study of the Effects of RoActemra/Actemra (Tocilizumab) on Neutrophils in Patients With Active Rheumatoid Arthritis Who Have an Inadequate Response to Biologic and/or Non-biologic DMARDs.

Rheumatoid Arthritis

United Kingdom
GlaxoSmithKline

Completed

Subject Insights to Understand Rheumatoid Arthritis (RA)

Arthritis, Rheumatoid

United Kingdom
Western Health and Social Care Trust
University of Ulster

Withdrawn

Dataglove to Measure Joint Stiffness in Patients With Arthritis

Arthritis, Rheumatoid

United Kingdom
Birmingham Women's and Children's NHS Foundation...

Completed

Indo-cyanine Green (ICG) in Paediatric Oncology MIS

Rhabdomyosarcoma | Metastatic Osteosarcoma | Pulmonary Metastasis | Metastatic Ewing Sarcoma | Pediatric Renal Tumor | Non-Rhabdo. Soft Tissue Sarcoma

United Kingdom
University of Manchester
Dowager Countess Eleanor Peel Trust

Recruiting

Addressing Inequity in Dermatology

Dermatologic Disease

United Kingdom

Clinical Trials on Connective Tissue Diseases in United Kingdom

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