Clinical Trials on Corneal Dystrophies, Hereditary in Switzerland

Total 80 results

Daniela Nosch

Completed

Investigation in Corneal Sensation and Contact Lens Wear

Cornea | Sense Loss; Cornea

Switzerland
Okuvision GmbH
CONET GmbH - Clinical Operations Network

Completed

Retrospective NIS to Evaluate the Patient Benefit of TES

Retinitis Pigmentosa

Germany, Switzerland
Haag-Streit AG
University Hospital Inselspital, Berne

Completed

Study of Clinical Performance of Corneal Topography Measurement Using an Optical Biometer

Corneal Topography

Switzerland
Second Sight Medical Products
National Eye Institute (NEI)

Completed

Argus® II Retinal Stimulation System Feasibility Protocol

Retinitis Pigmentosa

United States, United Kingdom, France, Mexico, Switzerland
Jaeb Center for Health Research
Usher 1F Collaborative; Marjorie C. Adams Foundation

Active, not recruiting

Rate of Progression of PCDH15-Related Retinal Degeneration in Usher Syndrome 1F (RUSH1F)

Retinal Degeneration | Retinitis Pigmentosa | Eye Diseases, Hereditary

Switzerland, United States, Germany, Netherlands, Canada, France, Israel
Massachusetts General Hospital
Massachusetts Eye and Ear Infirmary

Completed

A Study to Test the Potential of Brillouin Microscopy for Biomechanical Properties Measurements in Human Cornea

Keratoconus | Pellucid Marginal Corneal Degeneration | Keratectasia

United States, Switzerland
University Hospital Inselspital, Berne

Active, not recruiting

Development of a Keratoconus Detection Algorithm by Deep Learning Analysis and Its Validation on Eyestar Images (DKDA)

Eye Diseases | Cataract | Keratoconus | Corneal Ectasia

Switzerland
Luzerner Kantonsspital

Completed

Corneal Uptake of Riboflavin Eye Drops

Keratoconus

Switzerland
Haag-Streit AG

Completed

Clinical Study - ES 900 - 2020-2

Cataract | Keratoconus

Switzerland
Janssen Research & Development, LLC
Janssen Research & Development, LLC

Active, not recruiting

Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene

X-Linked Retinitis Pigmentosa

Belgium, Canada, United States, Israel, United Kingdom, Spain, Denmark, France, Italy, Netherlands, Switzerland
Janssen Research & Development, LLC
Janssen Research & Development, LLC

Active, not recruiting

Follow-up Gene Therapy Trial for the Treatment of X-linked Retinitis Pigmentosa Associated With Variants in the RPGR Gene

X-Linked Retinitis Pigmentosa

United States, Canada, Israel, United Kingdom, Spain, Denmark, France, Belgium, Italy, Netherlands, Switzerland
Daniela Nosch

Completed

Investigation in Corneal Sensation

Cornea; Sense Loss

Switzerland
Daniela Nosch

Completed

Influence of Silicone Hydrogel Contact Lens Neophyte Wear on Corneal Sensitivity (CSCL)

Cornea

Switzerland
Daniela Nosch

Completed

Influence of Silicone Hydrogel Extended Contact Lens Wear on Corneal Sensitivity

Cornea

Switzerland
University Hospital Inselspital, Berne

Completed

The Ocular Microbiome in Patients With Dry Eye Disease

Dry Eye Disease

Switzerland
University Hospital, Geneva

Completed

Swiss PACK-CXL Multicenter Trial for the Treatment of Infectious Keratitis

Keratitis; Infectious Disease (Manifestation)

Switzerland
Insel Gruppe AG, University Hospital Bern
Stiftung OPOS; Fondation Bertarelli

Recruiting

Ocular Microbiome and Immune System in Dry Eyes

Dry Eye Disease

Switzerland
QLT Inc.

Completed

Natural History Study in Inherited Retinal Disease Subjects Caused by Mutations in RPE65 or LRAT

Leber Congenital Amaurosis (LCA) | Retinitis Pigmentosa (RP)

United States, Canada, Denmark, Germany, Netherlands, Switzerland, United Kingdom
University of Applied Sciences and Arts Northwestern...

Completed

Clinical Study to Evaluate the Efficacy of Ectoin® Containing Eye Spray for Treatment of Dry Eye Disease

Dry Eye

Switzerland
University of Applied Sciences and Arts Northwestern...

Completed

Evaluation of an Updated Version of the Program "BlinkBlink" for Alleviation of Dry Eye Symptoms Induced by Computer Work

Dry Eye Syndromes | Computer Vision Syndrome

Switzerland
Johns Hopkins University
Mayo Clinic; Medical University of Graz; Radboud University Medical Center; University... and other collaborators

Recruiting

Oral N-acetylcysteine for Retinitis Pigmentosa (NAC Attack)

Retinitis Pigmentosa

United States, Austria, Mexico, Netherlands, United Kingdom, Germany, Canada, Switzerland
Jaeb Center for Health Research
Foundation Fighting Blindness

Recruiting

Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants (Uni-Rare)

Retinitis Pigmentosa | Inherited Retinal Degeneration

United States, United Kingdom, France, Finland, Israel, Netherlands, Switzerland, Australia, Canada, Brazil, Mexico
Dr. Romain Lazor
Boehringer Ingelheim

Recruiting

Efficacy of Nintedanib for Treatment of Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT) Patients (EPISTOP)

Telangiectasia, Hereditary Hemorrhagic

Switzerland
University Children's Hospital, Zurich

Unknown

Cardiac Involvement in Patients With Duchenne/Becker Muscular Dystrophy

Duchenne / Becker Muscular Dystrophy

Switzerland
University Hospital, Basel, Switzerland

Completed

L-citrulline and Metformin in Duchenne's Muscular Dystrophy

Duchenne's Muscular Dystrophy (DMD)

Switzerland
University Hospital, Basel, Switzerland

Completed

L-citrulline and Metformin in Becker's Muscular Dystrophy

Becker's Muscular Dystrophy (BMD)

Switzerland
Interregionale Blutspende SRK

Enrolling by invitation

Quality and Biologic Characteristics of Red Blood Concentrates Obtained From Individuals With Elevated Ferritin.

Hereditary Hemochromatosis | Hyperferritinemia

Switzerland
Swiss Federal Institute of Technology
Instituto de Investigação em Imunologia

Completed

Inhibiting Dietary Iron Absorption in Subjects With Hereditary Hemochromatosis by a Natural Polyphenol Supplement

Iron Metabolism Disorders | Iron Overload | Polyphenols

Portugal, Switzerland
Institute of Molecular and Clinical Ophthalmology...

Recruiting

Function and Imaging Assessments for G1961E-associated Stargardt Disease (FIRSTORBIT)

Stargardt Disease | Stargardt Disease 1 | Fundus Flavimaculatus | Macular Degeneration, Stargardt | Macular Dystrophy With Flecks, Type 1

Switzerland
University Hospital, Basel, Switzerland

Recruiting

Leflunomide Treatment for MEN1 Patients - the LUMEN1 Trial (LUMEN1)

MEN1 Gene Mutation

Switzerland
University Hospital, Basel, Switzerland
Institute of Molecular and Clinical Ophthalmology Basel

Recruiting

EyeConic: Qualification for Cone-Optogenetics

Retinal Dystrophies

United States, Switzerland, China, Germany, Hungary, Italy, United Kingdom
Prof. Beck Popovic Maja

Terminated

A Prospective International Multicenter Clinical Trial for Eyes With Relapsed Retinoblastoma (EuRbG2018)

Eye Cancer, Retinoblastoma

Switzerland
Swiss Federal Institute of Technology

Completed

Evaluation of a Textile Scapula Orthosis (ScapOrthosis)

Muscle Weakness | Muscular Dystrophies | Muscular Dystrophy | Muscular Dystrophy, Facioscapulohumeral | Scapular Dyskinesis | Muscular Weakness

Germany, Switzerland
University Hospital Inselspital, Berne

Completed

Nutritional Assessment in Mitochondrial Cytopathy (NAMITO)

Mitochondrial Diseases | Mitochondrial Myopathies | Mitochondrial Cytopathies

Switzerland
Shire
Takeda Development Center Americas, Inc.

Active, not recruiting

A Study of Lanadelumab in Persons With Hereditary Angioedema (HAE) Type I or II (ENABLE)

Hereditary Angioedema (HAE)

Germany, Switzerland, Spain, Israel, Italy, Austria, Portugal, Kuwait
University of Basel

Recruiting

Cascade Genetic Testing for Hereditary Breast/Ovarian Cancer and Lynch Syndrome in Switzerland (CASCADE)

Lynch Syndrome | Hereditary Breast and Ovarian Cancer

Switzerland
BioCryst Pharmaceuticals

Completed

Efficacy and Safety of BCX7353 to Prevent Angioedema Attacks in Subjects With Hereditary Angioedema (APeX-1)

Hereditary Angioedema (HAE)

Canada, United Kingdom, Germany, Spain, Australia, Hungary, Italy, Austria, North Macedonia, Denmark, Switzerland
BioCryst Pharmaceuticals

Completed

Study of BCX7353 as a Treatment for Attacks of Hereditary Angioedema

Hereditary Angioedema (HAE)

Austria, Denmark, France, Germany, Hungary, Israel, Italy, North Macedonia, Poland, Romania, Switzerland, United Kingdom
University of Basel
National Cancer Center, Korea; University Hospital, Geneva; Swiss National Science... and other collaborators

Recruiting

The DIALOGUE Study: Swiss-Korean Billateral Collaboration (DIALOGUE)

Breast Cancer | Ovarian Cancer | Hereditary Cancer

Switzerland
University of Bern
University Hospital Inselspital, Berne; University of Lausanne Hospitals; University... and other collaborators

Recruiting

Swiss Registry for Neuromuscular Disorders (Swiss-Reg-NMD)

Congenital Muscular Dystrophy | SMA | DMD | BMD | IMD

Switzerland
University of Zurich

Recruiting

Exophthalmometry With 3D Face Scanners (EX3D)

Graves Ophthalmopathy | Exophthalmos | Orbital Fractures | Orbital Tumor

Switzerland
Institute of Molecular and Clinical Ophthalmology...

Recruiting

Progression Rate of Pseudoxanthoma Elasticum-associated Choroidal and Retinal Degeneration (PROPXE)

Pseudoxanthoma Elasticum

Switzerland
Christian Kern

Unknown

Severe and Transient Hypoxemia During Selective Intra-arterial Chemotherapy for Retinoblastoma in Children: Evaluation of the Right-sided Heart Function.

Retinoblastoma

Switzerland
CSL Behring
Chiltern International Inc.

Completed

Patient Registry Study of Berinert® in Normal Clinical Practice

Includes: Hereditary Angioedema

United States, Denmark, Germany, Switzerland
University Hospital Inselspital, Berne

Recruiting

High Resolution Optical Coherence Tomography

Glaucoma | Macular Degeneration | Uveitis | Diabetic Retinopathy | Diabetic Macular Edema | Macular Edema | Retinal Vein Occlusion | Optic Nerve Diseases | Retinal Detachment | Macular Disease | Retinal Disease | Retinal Neovascularization | Retinal Artery Occlusion | Hypertensive Retinopathy | Retinal Edema | Retinal Dystrophy

Switzerland
Shire
Jerini AG

Completed

EASSI - Evaluation of the Safety of Self-Administration With Icatibant (EASSI)

Hereditary Angioedema

Spain, Argentina, Austria, Denmark, France, Germany, Israel, Italy, Switzerland, United Kingdom
University Hospital, Basel, Switzerland

Completed

Tamoxifen in Duchenne Muscular Dystrophy (TAMDMD)

Duchenne Muscular Dystrophy

France, Spain, Germany, Netherlands, Switzerland, United Kingdom
Novartis Pharmaceuticals

Completed

A Trial to Evaluate the Safety, Local Tolerability, Pharmacokinetics and Pharmacodynamics of LDE225 on Skin Basal Cell Carcinomas in Gorlin Syndrome Patients

Treatment for Basal Cell Carcinomas (BCCs) in Gorlin Syndrome Patients

Austria, Switzerland
Novartis Pharmaceuticals

Completed

Study to Evaluate the Efficacy and Safety of Deferasirox Film-coated Tablet Versus Phlebotomy in Patients With Hereditary Hemochromatosis (HH)

Hereditary Hemochromatosis

Belgium, France, Russian Federation, Romania, Slovakia, Spain, Switzerland
BioCryst Pharmaceuticals

Completed

A Long Term Safety Study of BCX7353 in Hereditary Angioedema (APeX-S)

Hereditary Angioedema | Prophylaxis | HAE

Austria, Denmark, France, Germany, Hungary, Israel, Italy, North Macedonia, Poland, Switzerland, United Kingdom, United States, Australia, Hong Kong, Korea, Republic of, New Zealand, Serbia, Slovakia, South Africa, Spain

Clinical Trials on Corneal Dystrophies, Hereditary in Switzerland

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Romania

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Rare Diseases

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