Clinical Trials on Corneal Epithelial Disorders

Total 164897 results

Arbor Center for Eye Care

Terminated

Safety and Efficacy of Corneal Crosslinking Using the PXL-Platinum 330 for Eyes With Corneal Ectatic Conditions

Keratoconus | Cornea Ectasia

United States
Peter Wiedemann
Institut für Angewandte Trainingswissenschaft

Unknown

The Postoperative Head Position as a Predictor of the Surgical Outcome After DMEK

Pseudophakic Bullous Keratopathy | Fuchs Endothelial Corneal Dystrophy | Chemical Burn of Cornea | Posterior Polymorphous Corneal Dystrophy

Germany
Zhaoke (Guangzhou) Ophthalmology Pharmaceutical...

Completed

A Phase II Clinical Trial to Evaluate the Efficacy and Safety of ZKY001 Eye Drops (TPRK)

Corneal Epithelium Defect

China
TBF Genie Tissulaire

Withdrawn

Use of a Biological Lens of Amniotic Membrane (LV-Visio-AMTRIX) in the Treatment of Trophic Ulcers

Corneal Ulcer | Persistent Corneal Epithelial Defect
Lentechs, LLC

Completed

Corneal Oxygen Uptake With Apioc Contact Lenses

Contact Lens-Induced Corneal Disorder of Both Eyes (Diagnosis)

United States
Benha University

Not yet recruiting

Topical Insulin Versus Autologous Serum After Corneal Surgeries

Corneal Epithelial Wound

Egypt
University of Erlangen-Nürnberg Medical School

Unknown

Ripasudil 0.4% Eye Drops in Fuchs Endothelial Corneal Dystrophy

Fuchs' Endothelial Dystrophy | Fuchs Dystrophy | Corneal Endothelial Dystrophy | Corneal Endothelial Cell Loss | Cornea Guttata

Germany
University of Milan

Completed

Evaluation of the Efficacy of OMK2 in Recovering Corneal Neural Damage in Patients With Diabetes

Cornea

Italy
Eyegate Pharmaceuticals, Inc.

Completed

Safety and Effectiveness of OBG vs.a Bandage Contact Lens for Large Corneal Epithelial Defects in Patients Post-PRK.

Corneal Epithelial Wound

United States
Tissue Tech Inc.

Completed

Optimizing the Ocular Surface Prior to Cataract Surgery

Corneal Dystrophy, Epithelial Basement Membrane

United States
Royan Institute

Completed

Utilization of Amniotic Membrane Extract Eye Drop (AMEED) on Human Corneal Healing

Cornea Injury
The Cleveland Clinic

Recruiting

Corneal Elastography and Patient Specific Modeling

Refractive Errors | Keratoconus | Cornea; Ectasia

United States
National Taiwan University Hospital

Completed

Corneal Epithelial Wound Healing Difference Between Human Autoserum and Cord Blood Serum

Corneal Epithelial Wound Healing

Taiwan
Donnenfeld, Eric, M.D.

Completed

Effect of Topical Fluoroquinolones on Epithelial Wound Healing After PRK

Corneal Epithelial Wound Healing
Oregon Health and Science University
National Eye Institute (NEI)

Recruiting

Scleral Lens Fitting Using Wide-Field OCT

Keratoconus | Irregular; Contour of Cornea

United States
Centre Hospitalier Universitaire de Saint Etienne

Completed

Immunosuppression During Penetrating Keratoplasty, Using a Subconjunctival Implant Releasing Dexamethasone : Tolerance and Safety Pilot Study (IDEXACOR)

Keratoconus | Fuchs' Endothelial Dystrophy | Congenital Hereditary Stromal Dystrophy of the Cornea

France
Pacific Clear Vision Institute

Recruiting

Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Collagen Cross-Linking in Eyes With Corneal Thinning Conditions

Keratoconus, Unstable | Bacterial Keratitis | Ectasia of Cornea

United States
Centro Hospitalar de Vila Nova de Gaia/Espinho,...

Completed

Topical Insulin - Utility and Results in Neurotrophic Keratopathy in Stages 2 and 3

Neurotrophic Keratitis | Corneal Ulcer | Corneal Perforation | Corneal Epithelium Defect

Portugal
Augusta University
Novartis

Completed

GenTeal in Perioperative Treatment of Laser Assisted in Situ Keratomileusis LASIK Patients

Corneal Epithelium Defect

United States
Fang Duan

Unknown

0.3% Sodium Hyaluronate Eye Drop to Prevent Recurrent Corneal Epithelium Exfoliation

Corneal Epithelium Exfoliation

China
Occyo GmbH
University Clinic for Ophthalmology and Optometry- Salzburg

Completed

CDL Validation Study

Limbal Stem-cell Deficiency | Cornea Disease | Eyes Dry Chronic | Chronic Conjunctivitis of Both Eyes | Eye Lesion | Eye Disease; Cataract | Eyes Dry Feeling of | Cornea Inflamed | Cornea; Injury, Abrasion | Cornea Infection

Austria
Boston Children's Hospital

Recruiting

fMRI and IVCM Cornea Microscopy of CXL in Keratoconus

Pain, Postoperative | Surgical Wound | Pain, Acute | Keratoconus | Pain, Chronic | Surgical Injury | Cornea | Cornea Injury

United States
Glia, LLC

Completed

Prolongation of Contact Lens Comfortable Wear Duration by CLM2 Topical Gel

Contact Lens Discomfort | Contact Lens-induced Corneal Disorder | Contact Lens Acute Red Eye | Contact Lens-induced Corneal Fluorescein Staining

United States
KeraMed, Inc.
National Eye Institute (NEI); ClinReg Consulting Services, Inc.

Terminated

A Clinical Study to Evaluate the KeraKlear Keratoprosthesis in Patients With Corneal Opacity

Corneal Blindness

United States
London Vision Clinic
Arcscan, Inc.

Suspended

Repeatability and Reproducibility of the ArcScan Insight 100 VHF Digital Ultrasound

Corneal Thickness Measurement | Epithelial Thickness Measurement | Anterior Eye Segment Measurements

United Kingdom
Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical...
National Taiwan University Hospital

Completed

Influence of Cosmetic Color Tinted Contact Lenses on the Ocular Surface

Corneal Epithelial Wound | Conjunctival Infections, Irritations and Inflammations | Hypertrophy; Conjunctiva | Corneal Pannus

Taiwan
King Khaled Eye Specialist Hospital

Completed

Treatment of PED With AMT and Autologous Serum

Corneal Epithelial Defect

Saudi Arabia
CorNeat Vision Ltd.

Recruiting

Study to Evaluate the Clinical Safety and Performance of the CorNeat KPro for Treatment of Corneal Blindness

Corneal Opacity | Corneal Disease | Corneal Injuries

France, Canada, Israel, Netherlands
Centre Hospitalier Universitaire de Saint Etienne
Kali Care

Completed

Data Collection of Therapeutic Compliance in Patients Receiving Corneal Graft Using a Collection Box for Corticosteroid Eye Drops (KALICORT)

Corticosteroid | Corneal Graft Disorder (Disorder)

France
Centre Hospitalier Régional Metz-Thionville

Completed

Predictive Factors of Graft Detachment Following Dmek (PDF DMEKDETACH)

Pseudophakic Bullous Keratopathy | Fuchs' Endothelial Corneal Dystrophy | Descemet Membrane Endothelial Keratoplasty | Graft Detachment

France
ProQR Therapeutics

Withdrawn

Study With QR-504a to Evaluate Safety, Tolerability & Corneal Endothelium Molecular Biomarker(s) in Subjects With FECD3 (Fuchs Focus)

Corneal Diseases | Fuchs Endothelial Corneal Dystrophy | FECD3 | LRS | Descemet's Membrane Disorder

United Kingdom
Keratoplasty Alliance International

Recruiting

Developing a Nationwide Registry to Track Longitudinal Clinical Outcomes of Corneal Surgery and Disease

Corneal Disease | Corneal Transplant Failure | Endothelial Corneal Dystrophy | Corneal Transplant Rejection

United States
Centre Hospitalier Régional Metz-Thionville

Completed

Visual Outcomes Following Descemet Stripping Automated Endothelial Keratoplasty (VO-DSAEK)

Corneal Endothelial Disorder
CorNeat Vision Ltd.

Terminated

First in Human (FIH) Study to Assess Safety and Efficacy of the CorNeat KPro for the Treatment of Corneal Blindness

Corneal Opacity | Corneal Disease | Corneal Injuries

France, United States, Canada, Netherlands, Israel
Oregon Health and Science University
National Eye Institute (NEI); National Institutes of Health (NIH)

Completed

Corneal Opacities in Children (OCT)

Corneal Opacities

United States
Klinikum Klagenfurt am Wörthersee
University of Klagenfurt

Recruiting

Influence of Pupillary Behavior During Eye Surgery on Morphological and Functional Outcome

Cataract | Corneal Disease | Vitreous Disorder

Austria
Vissum, Instituto Oftalmológico de Alicante
Instituto de Salud Carlos III; Universidad Miguel Hernandez de Elche

Completed

Autologous Adipose-Derived Adult Stem Cell Implantation for Corneal Diseases (ADASCs-CT-CD) (ADASCs-CT-CD)

Keratoconus | Treatment | Therapy | Corneal Dystrophy | Ophthalmological Disorder

Spain
Umeå University
Glaukos Corporation

Completed

Photorefractive Intrastromal Crosslinking (PiXL) for the Treatment of Progressive Keratoconus

Eye Diseases | Keratoconus | Corneal Disease | Corneal Crosslinking | Corneal Biomechanics | Corneal Densitometry | Scheimpflug Photography

Sweden
London Vision Clinic
Carl Zeiss Meditec AG

Suspended

Repeatability, Reproducibility and Comparison of Cirrus OCT, RTVue OCT, MS-39 OCT, and Insight 100 VHFDU

Corneal Thickness Measurement | Epithelial Thickness Measurement | LASIK Flap Thickness Measurement | SMILE Cap Thickness Measurement

United Kingdom
University of California, Irvine

Withdrawn

SINGLE PATIENT EXPANDED ACCESS OF A PROSPECTIVE, MULTICENTER CLINICAL TRIAL DESIGNED TO EVALUATE THE SAFETY AND PROBABLE BENEFIT OF THE KERAKLEAR NON-PENETRATING KERATOPROSTHESIS IN SUBJECTS WITH CORNEAL OPACITY WITH POOR PROGNOSIS FOR CORNEAL TRANSPLANT

CORNEAL OPACITY WITH POOR PROGNOSIS FOR CORNEAL TRANSPLANT

United States
Cornea and Laser Eye Institute

Active, not recruiting

Wavefront Guided Scleral Lenses for Keratoconus and Irregular Astigmatism (WFG Sclerals)

Keratoconus | Corneal Ectasia | Irregular Astigmatism | Aberration, Corneal Wavefront | Wavefront Aberration, Corneal | Pellucid Marginal Corneal Degeneration | Keratoglobus

United States
National Taiwan University Hospital

Completed

Topical Autologous Insulin Application for the Treatment of Corneal Epithelium Defect After Ocular Surgeries

Corneal Epithelial Defects After Ocular Surgeries

Taiwan
Klinikum Chemnitz gGmbH
Technische Universität Dresden

Completed

Safety Study of a Sutureless Amniotic Membran Transplantation to Treat Ocular Surface Disorders (Expanded Access) (AmnioClip)

Corneal Ulcers | Corneal Melting

Germany
University Hospital, Strasbourg, France

Terminated

Robotic Surgery of the Ocular Surface

Keratitis | Pterygium | Corneal Perforation | Corneal Opacity Corneal Thinning

France
Tianjin Eye Hospital

Recruiting

Artificial Intelligence for Screening of Multiple Corneal Diseases

Deep Learning, Corneal Disease, Screening

China
Lundquist Institute for Biomedical Innovation at...
University of California, Los Angeles; Thrasher Research Fund; L.V. Prasad Eye... and other collaborators

Completed

A Clinical Trial of Povidone-Iodine for the Treatment of Bacterial Corneal Ulcers

Corneal Ulcer | Bacterial Keratitis | Infected Corneal Ulcers | Childhood Blindness

United States
University of Texas Southwestern Medical Center

Completed

Early Experience With Descemet's Stripping Automated Endothelial Keratoplasty (DSAEK)

Corneal Edema Secondary to Corneal Endothelial Dystrophy

United States
UMC Utrecht
Universitaire Ziekenhuizen KU Leuven; Maastricht University Medical Center; Carl...

Completed

The ADVISE Study: Advanced Visualization In Corneal Surgery Evaluation (ADVISE)

Vision Disorders | Fuchs Dystrophy | Bullous Keratopathy | Endothelial Corneal Dystrophy

Netherlands, Belgium
Assiut University

Not yet recruiting

Platelet Rich Plasma in Corneal Surface Diseases

Dry Eye | Persistent Corneal Epithelial Defects
University of California, San Francisco
FDA Office of Orphan Products Development

Terminated

Efficacy and Safety Study of Nexagon for Persistent Corneal Epithelial Defects (NTX-PED-001)

Persistent Corneal Epithelial Defects

Clinical Trials on Corneal Epithelial Disorders

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mauritius

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Rare Diseases

Drug Interventions

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