Clinical Trials on Corneal Transplantation

Total 3998 results

Arbor Center for Eye Care

Terminated

Safety and Efficacy of Corneal Crosslinking Using the PXL-Platinum 330 for Eyes With Corneal Ectatic Conditions

Keratoconus | Cornea Ectasia

United States
University of Erlangen-Nürnberg Medical School

Unknown

Ripasudil 0.4% Eye Drops in Fuchs Endothelial Corneal Dystrophy

Fuchs' Endothelial Dystrophy | Fuchs Dystrophy | Corneal Endothelial Dystrophy | Corneal Endothelial Cell Loss | Cornea Guttata

Germany
University of Milan

Completed

Evaluation of the Efficacy of OMK2 in Recovering Corneal Neural Damage in Patients With Diabetes

Cornea

Italy
Royan Institute

Completed

Utilization of Amniotic Membrane Extract Eye Drop (AMEED) on Human Corneal Healing

Cornea Injury
Centre hospitalier de l'Université de Montréal...

Recruiting

Inflammatory Mediators of Glaucoma After Corneal Transplantation (AH-Tears) (AH-Tears)

Inflammation | Glaucoma | Corneal Transplantation

Canada
The Cleveland Clinic

Recruiting

Corneal Elastography and Patient Specific Modeling

Refractive Errors | Keratoconus | Cornea; Ectasia

United States
Oregon Health and Science University
National Eye Institute (NEI)

Recruiting

Scleral Lens Fitting Using Wide-Field OCT

Keratoconus | Irregular; Contour of Cornea

United States
Centre Hospitalier Universitaire de Saint Etienne

Completed

Immunosuppression During Penetrating Keratoplasty, Using a Subconjunctival Implant Releasing Dexamethasone : Tolerance and Safety Pilot Study (IDEXACOR)

Keratoconus | Fuchs' Endothelial Dystrophy | Congenital Hereditary Stromal Dystrophy of the Cornea

France
Pacific Clear Vision Institute

Recruiting

Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Collagen Cross-Linking in Eyes With Corneal Thinning Conditions

Keratoconus, Unstable | Bacterial Keratitis | Ectasia of Cornea

United States
Centre hospitalier de l'Université de Montréal...

Recruiting

Endoscopic Assisted Anterior Hyaloid Peeling in Boston Type 1 Keratoprosthesis (KPro-HP-Endo) (KPro-HP-Endo)

Postoperative Complications | Endoscopy | Vitrectomy | Corneal Transplantation | Glaucoma and Ocular Hypertension

Canada
Occyo GmbH
University Clinic for Ophthalmology and Optometry- Salzburg

Completed

CDL Validation Study

Limbal Stem-cell Deficiency | Cornea Disease | Eyes Dry Chronic | Chronic Conjunctivitis of Both Eyes | Eye Lesion | Eye Disease; Cataract | Eyes Dry Feeling of | Cornea Inflamed | Cornea; Injury, Abrasion | Cornea Infection

Austria
Boston Children's Hospital

Recruiting

fMRI and IVCM Cornea Microscopy of CXL in Keratoconus

Pain, Postoperative | Surgical Wound | Pain, Acute | Keratoconus | Pain, Chronic | Surgical Injury | Cornea | Cornea Injury

United States
Santen Inc.
Vistakon Pharmaceuticals

Terminated

Ocular Penetration of 1.5% Levofloxacin and 0.5% Moxifloxacin During Corneal Transplant Surgery

Corneal Transplantation

United States
Astellas Pharma Europe Ltd.

Active, not recruiting

Study to Compare the Pharmacokinetics of Tacrolimus in Stable Pediatric Allograft Recipients Converted From Prograf® to Advagraf®

Liver Transplantation | Kidney Transplantation | Heart Transplantation | Lung Transplantation | Intestine Transplantation

Belgium, Czechia, France, Germany, Italy, Poland, United Kingdom
Astellas Pharma Inc
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate FK778 in Kidney Transplant Patients

Kidney Transplantation | Renal Transplantation | Transplantation, Kidney | Grafting, Kidney | Transplantation, Renal

Belgium, Germany, Spain, Sweden, Italy, Switzerland, United Kingdom, Austria, France, Poland, Czech Republic, Netherlands
Keratoplasty Alliance International

Recruiting

Developing a Nationwide Registry to Track Longitudinal Clinical Outcomes of Corneal Surgery and Disease

Corneal Disease | Corneal Transplant Failure | Endothelial Corneal Dystrophy | Corneal Transplant Rejection

United States
Oregon Health and Science University
National Eye Institute (NEI); National Institutes of Health (NIH)

Completed

Corneal Opacities in Children (OCT)

Corneal Opacities

United States
Astellas Pharma Europe Ltd.

Completed

A Study to Compare How the Body Absorbs and Processes Two Different Formulations of the Anti-rejection Medication Tacrolimus (Advagraf® or Prograf®) in Children Receiving an Organ Transplant, and How Safe and Effective They Are Over a Longer Period of Time

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Czechia, France, Italy, Poland, United Kingdom
The Hospital for Sick Children

Completed

Pharmacogenetic Trial of Tacrolimus After Pediatric Transplantation

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Canada
Astellas Pharma Europe Ltd.

Terminated

A Paediatric, Open, Follow up Study With Modigraf Examining Safety and Efficacy in de Novo Allograft Recipients (PROGRESSION)

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Belgium, France, Germany, Poland, Spain, United Kingdom
Astellas Pharma Europe Ltd.

Completed

Study to Ascertain if Prolonged Release Tacrolimus (FK506E - MR4) is Safe and Effective When Used in the Long Term and in Combination With Other Immunosuppressive Drugs in Patients Who Have Received a Transplant

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Spain, Australia, France, Germany, Canada, Italy, United Kingdom, Belgium, South Africa, Switzerland, Sweden, United States, Austria, Brazil, Czechia, Denmark, Finland, Hungary, Ireland, Mexico, Netherlands, New Zealand, Poland
Astellas Pharma Europe Ltd.

Completed

A Study to Determine Pharmacokinetics of Children Receiving Modigraf (Tacrolimus Granules) Following Solid Organ Transplantation (OPTION)

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Belgium, France, Germany, Poland, Spain, United Kingdom
Umeå University
Glaukos Corporation

Active, not recruiting

Epi-on PiXL for the Treatment of Progressive Keratoconus.

Eye Diseases | Keratoconus | Corneal Crosslinking | Corneal Densitometry | Scheimpflug Photography | Corneal Disorder

Sweden
Umeå University
Glaukos Corporation

Completed

Photorefractive Intrastromal Crosslinking (PiXL) for the Treatment of Progressive Keratoconus

Eye Diseases | Keratoconus | Corneal Disease | Corneal Crosslinking | Corneal Biomechanics | Corneal Densitometry | Scheimpflug Photography

Sweden
University of California, Irvine

Withdrawn

SINGLE PATIENT EXPANDED ACCESS OF A PROSPECTIVE, MULTICENTER CLINICAL TRIAL DESIGNED TO EVALUATE THE SAFETY AND PROBABLE BENEFIT OF THE KERAKLEAR NON-PENETRATING KERATOPROSTHESIS IN SUBJECTS WITH CORNEAL OPACITY WITH POOR PROGNOSIS FOR CORNEAL TRANSPLANT

CORNEAL OPACITY WITH POOR PROGNOSIS FOR CORNEAL TRANSPLANT

United States
Astellas Pharma Inc

Completed

Study to Compare the Pharmacokinetics of Tacrolimus in Adult Transplant Recipients Treated With Advagraf® or Prograf®

Heart Transplantation | Lung Transplantation | Pancreas (Including SPK) Transplantation

France, United Kingdom, Taiwan, Belgium, Italy, Austria
Emory University

Completed

Quality of Life in Pediatric Transplant Recipients

Liver Transplantation | Kidney Transplantation | Heart Transplantation | Lung Transplantation | Heart-Lung Transplantation

United States
Cornea and Laser Eye Institute

Active, not recruiting

Wavefront Guided Scleral Lenses for Keratoconus and Irregular Astigmatism (WFG Sclerals)

Keratoconus | Corneal Ectasia | Irregular Astigmatism | Aberration, Corneal Wavefront | Wavefront Aberration, Corneal | Pellucid Marginal Corneal Degeneration | Keratoglobus

United States
Andrasko, Gary, OD, LLC
Alcon Research

Unknown

Evaluation of Corneal Staining With Various Contact Lens/Solution Combinations

Corneal Staining | Corneal Epithelial Disruption

United States
Klinikum Chemnitz gGmbH
Technische Universität Dresden

Completed

Safety Study of a Sutureless Amniotic Membran Transplantation to Treat Ocular Surface Disorders (Expanded Access) (AmnioClip)

Corneal Ulcers | Corneal Melting

Germany
University Hospital, Strasbourg, France

Terminated

Robotic Surgery of the Ocular Surface

Keratitis | Pterygium | Corneal Perforation | Corneal Opacity Corneal Thinning

France
Novartis

Completed

Conversion Trial From Mycophenolate Mofetil (MMF) to Enteric-coated Mycophenolate Sodium (EC-MPS) in Stable Transplanted Patients Suffering From Gastrointestinal (GI) Adverse Events While on Mycophenolate Mofetil Therapy (MMF) Therapy

Liver Transplantation | Kidney Transplantation

Switzerland
University of Wisconsin, Madison

Terminated

Cytokine Kinetics Test to Assess the Presence or Absence of Tolerance in Organ Transplant

Liver Transplantation | Kidney Transplantation

United States
Nantes University Hospital

Unknown

A Study To Compare Sirolimus Versus Tacrolimus In De Novo Simultaneous Pancreas- Kidney Allograft Recipients Receiving An Induction Therapy With Antithymocyte Globulin Plus Mycophenolate Mofetil Plus Corticosteroids

Kidney Transplantation | Pancreas Transplantation

France
University Hospital, Gasthuisberg
Juvenile Diabetes Research Foundation; Fund for Scientific Research, Flanders...

Unknown

Insulin Secretory Capacity in Insulin-independent Pancreas-Kidney Recipients Compared to Controls

Kidney Transplantation | Pancreas Transplantation

Belgium
National Taiwan University Hospital

Unknown

Sirolimus Blood Concentrations on Conversion From Oral Solution to Tablets

Kidney Transplantation | Immunosuppression | Transplantation

Taiwan
Tianjin Eye Hospital

Recruiting

Artificial Intelligence for Screening of Multiple Corneal Diseases

Deep Learning, Corneal Disease, Screening

China
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Treg Cell Therapy in Liver and Kidney Transplantation - Preclinical Validation of Batches of Treg Cells Amplified in Vitro (PRE-TREG)

Liver Transplantation | Kidney Transplantation

France
Emory University

Recruiting

Immune Monitoring and Assay Development in Organ Transplant Recipients (IMP)

Organ Transplantation | Transplantation Immunology

United States
Astellas Pharma China, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of a Modigraf® Based Immunosuppression Regimen in De Novo Pediatric Allograft Liver and Kidney Transplantation Recipients

Liver Transplantation | Kidney Transplantation

China
Astellas Pharma China, Inc.

Completed

A Study of Modigraf® (Tacrolimus Granules) to Evaluate the Pharmacokinetics and Long-term Safety and Efficacy in De Novo Pediatric Allograft Liver and Kidney Transplantation Recipients

Liver Transplantation | Kidney Transplantation

China
University of Nebraska

Completed

Pre-operative Evaluation of Kidney & Pancreas Transplant Patients

Kidney Transplantation | Pancreas Transplantation

United States
Rennes University Hospital

Completed

Impact of P-gp, MRP2, ENT-1 and CNT3 on the Blood Concentration / Intra-PBMC Concentration of Tacrolimus (TRANS-TAC)

Liver Transplantation | Kidney Transplantation

France
Bristol-Myers Squibb

Completed

Pattern Of Use Of Belatacept In US Transplant Recipients

Kidney Transplantation: Transplantation, Kidney
Helsinki University Central Hospital
Tampere University Hospital

Completed

Immunogenicity of 13-valent Pneumococcal Conjugate Vaccine Compared to the Pneumococcal Polysaccharide Vaccine in Adult Kidney and Liver Transplant Patients (SOT13)

Liver Transplantation | Kidney Transplantation

Finland
National Taiwan University Hospital

Unknown

The Influence of ABCB1、CYP3A4、CYP3A5、POR Genetic Polymorphism and Other Factors on Tacrolimus Blood Concentration

Liver Transplantation | Kidney Transplantation

Taiwan
Astellas Pharma Inc

Completed

A Study to Demonstrate Safety and Efficacy of Advagraf in Patients Undergoing Kidney or Liver Transplantation in India

Liver Transplantation | Kidney Transplantation

India
University of Manchester
Manchester University NHS Foundation Trust

Unknown

CEUS in Kidney and Pancreas Transplantation

Kidney Transplantation | Pancreas Transplantation

United Kingdom
National Taiwan University Hospital
National Science Council, Taiwan

Unknown

Organ Transplantation Rehabilitation: Effect of Bedside Exercise Device and Activity Reinforcement

Liver Transplantation | Heart Transplantation

Taiwan
University of Oslo School of Pharmacy

Completed

Intracellular and Renal/Myocardial Tissue Concentrations of Cyclosporine A (CsA) and Rejection Frequency Following Transplantation

Heart Transplantation | Renal Transplantation

Norway

Clinical Trials on Corneal Transplantation

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