Clinical Trials on Critical Lower Limb Ischaemia

Total 873 results

National University of Ireland, Galway, Ireland
University Hospital of Limerick

Completed

Autologous Stem Cells for the Treatment of No Option Critical Limb Ischemia

Critical Limb Ischemia

Ireland
Hull University Teaching Hospitals NHS Trust

Completed

Exercise In Critical Limb Ischaemia Patients Having Surgery Proof of Concept (EXERCISE)

Critical Limb Ischemia

United Kingdom
Leonardo Clavijo
Amgen

Unknown

Effect of Evolocumab in Patients With Critical Limb Ischemia (Evol-CLI) (Evol-CLI)

Critical Limb Ischemia

United States
AnGes USA, Inc.

Completed

A Long Term Follow-up Study of AMG0001 in Subjects With Critical Limb Ischemia

Critical Limb Ischemia

United States
Libella Gene Therapeutics

Unknown

Evaluation of Safety and Tolerability of Libella Gene Therapy for Critical Limb Ischemia: AAV- hTERT

Critical Limb Ischemia

Colombia
University of Southern California

Completed

Aspirin and Clopidogrel Reactivity in Patients With Critical Limb Ischemia (CLI)

Critical Limb Ischemia

United States
University of Southern California

Completed

Switch to Ticagrelor in Critical Limb Ischemia Anti-platelet Study (STT-CLIPS)

Critical Limb Ischemia

United States
Baylor Research Institute

Completed

Laser Atherectomy Versus Angioplasty for the Treatment of Critical Limb Ischemia

Critical Limb Ischemia

United States
University of Florence
Tuscany Region

Completed

Monocentric Trial: Stem Cell Emergency Life Threatening Limbs Arteriopathy (SCELTA) (SCELTA)

Critical Limb Ischemia

Italy
Hospital Universitario Getafe

Completed

Revascularization in Nonagenarian Patients With Critical Lower Limb Ischaemia (NONA-CLI)

Critical Limb Ischemia
Stempeutics Research Pvt Ltd

Completed

Mesenchymal Stem Cells in Critical Limb Ischemia

Critical Limb Ischemia

India
Leonardo Bolognese, MD

Completed

Drug Eluting Balloon in peripherAl inTErvention For Below The Knee Angioplasty Evaluation (DEBATE-BTK)

Critical Limb Ischemia

Italy
HyperMed
Carl T. Hayden VA Medical Center

Unknown

Validation of OxyVu for Assessing Level of Amputation With Comparison to Other Modalities (LOA)

Critical Limb Ischemia

United States
Medical University of Vienna

Unknown

Viennese Registry on Patients With Chronic Critical Limb Ischemia

Chronic (> 2 Weeks) Critical Ischemia With Skin Defect in Lower Limbs

Austria
Biotyx Medical (Shenzhen) Co., Ltd.

Recruiting

IBS Titan vs. PTA in Patients With Infrapopliteal Arterial Stenosis or Occlusive Disease (GENIUS)

Critical Limb Ischemia (CLI)

China
Andalusian Initiative for Advanced Therapies -...
Iniciativa Andaluza en Terapias Avanzadas

Terminated

Clinical Trial I/II Opened, Randomized and Controlled for the Study of the Use of Stem Cells Therapy in Insulinized Diabetic Patients Type 2 With Critical Ischemia in Lower Limbs (CLI): Study of the Needs of Insulin

Critical Limb Ischemia (CLI)

Spain
Pluristem Ltd.

Unknown

Efficacy, Tolerability and Safety of Intramuscular Injections of PLX PAD for the Treatment of Subjects With Critical Limb Ischemia (CLI) With Minor Tissue Loss Who Are Unsuitable for Revascularization

Critical Limb Ischemia (CLI)

Germany, United Kingdom, Hungary, United States, Bulgaria, Czechia, Israel, North Macedonia, Poland
Temple University

Unknown

External Compression Therapy for Secondary Prevention of Lower-Limb Loss and Cardiovascular Mortality (ArtAssist)

Critical Limb Ischemia

United States
SurModics, Inc.

Completed

Safety and Feasibility of Surmodics SUNDANCE™ Drug Coated Balloon (SWING)

Peripheral Arterial Disease | Critical Lower Limb Ischemia

New Zealand, Australia, Austria, Germany, Latvia
University Hospital, Angers

Not yet recruiting

NOrmoBaric Oxygen Therapy Use In Critical Limb ISchemia (NOBILIS)

Critical Ischemia Limb

France
Abbott Medical Devices

Active, not recruiting

LIFE-BTK PK Sub-study

Critical Limb Ischemia (CLI)

Taiwan, United States, Australia
Pluristem Ltd.

Available

Expanded Access Treatment of Subjects With Critical Limb Ischemia (CLI) With Minor Tissue Loss Who Are Unsuitable for Revascularization

Critical Limb Ischemia (CLI)

United States
WideTrial, Inc.

Available

Expanded Access for Treatment Use of PLX-PAD in Critical Limb Ischemia (CLI)

Critical Limb Ischemia (CLI)
Cesca Therapeutics, Inc.

Unknown

Critical Limb Ischemia Rapid Delivery by SurgWerks-CLI Kit and VXP System (CLIRST III)

Critical Limb Ischemia (CLI)
Abbott Medical Devices

Active, not recruiting

LIFE-BTK Randomized Controlled Trial (LIFE-BTK)

Critical Limb Ischemia (CLI)

United States, Hong Kong, Australia, New Zealand, Singapore, Taiwan
Andalusian Initiative for Advanced Therapies -...
Iniciativa Andaluza en Terapias Avanzadas

Completed

Application of Cell Regeneration Therapy With Mesenchymal Stem Cells From Adipose Tissue in Critical Chronic Ischemic Syndrome of Lower Limbs (CLI) in Nondiabetic Patients.

Critical Limb Ischemia

Spain
Xuanwu Hospital, Beijing

Recruiting

Excimer Laser Combined With DCB Compared With Angioplasty Alone in the Treatment of Infrapopliteal Lesions.

Critical Limb Ischemia | Infrapopliteal Lesions

China
National University of Malaysia
Cytopeutics Sdn. Bhd.

Unknown

Intramuscular Mononuclear Cells and Mesenchymal Stem Cells Transplantation to Treat Chronic Critical Limb Ischemia

Critical Limb Ischemia

Malaysia
Ospedale San Donato

Unknown

Comparison of Sirolimus vs Paclitaxel Drug Eluting Balloon for Below-the-knee Angioplasty in Critical Limb Ischemia (DebateBTKDuell)

Drug Effect | Critical Limb Ischemia

Italy
Maria Cecilia Hospital

Completed

Laboratory, Cellular and Molecular Determinants of Clinical Success in Diabetic Patients With Critical Limb Ischemia (ECAD-CLI)

Diabetes Mellitus | Diabetic Foot | Critical Limb Ischemia | Critical Lower Limb Ischemia

Italy
Southwest Regional Wound Care Center

Completed

A Retrospective Analysis of Patients With Full Thickness Wounds in Limbs With Critical Ischemia

Critical Limb Ischemia

United States
Stanford University
National Heart, Lung, and Blood Institute (NHLBI); Medtronic Endovascular

Enrolling by invitation

The Use of FlowMet-R Technology to Predict Wound Healing in CLI Patients in a Wound Care Center Setting

Critical Limb Ischemia

United States
Andalusian Initiative for Advanced Therapies -...
Iniciativa Andaluza en Terapias Avanzadas

Completed

Intra-arterial Infusion of Autologous Bone Marrow Mononuclear Cells in Non-diabetic Patients With Critical Limb Ischemia (CLI).

Critical Limb Ischemia (CLI)

Spain
Kuopio University Hospital
Turku University Hospital; Helsinki University Central Hospital; Oulu University... and other collaborators

Recruiting

Paclitaxel Eluting Stent in Long SFA Obstruction: A Prospective, Randomized Comparison With Bypass Surgery (finnptx)

Claudication | Chronic Lower Limb Ischemia | Critical Ischemia | Peripheral Athero Obstructive Disease

Finland
University of Illinois at Chicago

Completed

Proteomics and Stem Cell Therapy as a New Vascularization Strategy

Critical Limb Ischemia

United States
Yonsei University

Unknown

Comparison of Cilostazol-based Triple Antiplatelet Therapy Versus Dual Antiplatelet Therapy for Outcomes of below-the Knee Endovascular Intervention in Patients With Critical Limb Ischemia (TAP CLI Study)

Critical Limb Ischemia

Korea, Republic of
Juventas Therapeutics, Inc.

Completed

Study to Evaluate the Safety and Efficacy of JVS-100 Administered to Adults With Critical Limb Ischemia

Critical Limb Ischemia

United States, India
Southern Arizona Vascular Institute
Southern Illinois University

Unknown

UT-15C SR in the Treatment of Critical Limb Ischemia

Critical Limb Ischemia

United States
Science Valley Research Institute
Wyeth is now a wholly owned subsidiary of Pfizer

Recruiting

Efficacy and Safety of Apixaban in Reducing Restenosis and Limb Loss in PAD Patients. (AGRIPPA)

Critical Limb Ischemia

Brazil
TotipotentSC Scientific Product Pvt. Ltd.
Thermogenesis Corp.

Completed

Safety and Efficacy of Autologous Bone Marrow Mononuclear Cells in Patients With Severe Critical Limb Ischemia

Critical Limb Ischemia

India
Ochsner Health System
United Therapeutics

Completed

Safety Study of UT-15C SR (Oral Treprostinil) in Patients Undergoing a Lower Limb Endovascular Procedure

Critical Limb Ischemia

United States
University Hospital, Angers

Completed

New Oxymetry Indices in Critical Limb Ischemia (NOVICE)

Critical Limb Ischemia

France
Vericel Corporation

Completed

An Efficacy and Safety Study of Ixmyelocel-T in Patients With Critical Limb Ischemia (CLI) (REVIVE)

Critical Limb Ischemia

United States
Cook Research Incorporated

Terminated

HemaTrate™ in the Treatment of Critical Limb Ischemia

Ischemia | Critical Limb Ischemia

United Kingdom
Helixmith Co., Ltd.

Completed

Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia

Critical Limb Ischemia

United States, Korea, Republic of
Helixmith Co., Ltd.

Completed

Safety Study of Gene Therapy in Treating Lower Leg Ischemia

Critical Limb Ischemia

United States
The Cleveland Clinic

Withdrawn

Correlation Between FlowMet™ and Other Gold Standard Assessments in the Management of Critical Limb Ischemia (CLI)

Critical Limb Ischemia

United States
Richard Burt, MD

Terminated

Efficacy and Safety of Umbilical Cord Blood Injection for Critical Limb Ischemia

Critical Limb Ischemia

United States
Clinical Centre of Serbia
University of California, Los Angeles

Unknown

Distal Venous Arterialisation of Ischemic Limb

Critical Limb Ischemia

Serbia
Lancashire Care NHS Foundation Trust
St. Franziskus Hospital

Unknown

Acute Limb Ischaemia (ALI) Management With 'Indigo' Mechanical Aspiration System

Lower Limb Ischemia

United Kingdom

Clinical Trials on Critical Lower Limb Ischaemia

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