Clinical Trials on Cutaneous Squamous Cell Carcinoma of the Head and Neck

Total 6440 results

Tempus AI
AstraZeneca

Recruiting

A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)

Head and Neck Squamous Cell Carcinoma

United States
Second Affiliated Hospital, School of Medicine,...

Recruiting

Real-world Analysis on the Efficacy and Safety of Neoadjuvant Therapy for Head and Neck Squamous Cell Carcinoma （neoHNSCC）

Head and Neck Squamous Cell Carcinoma

China
Ascendis Pharma Oncology Division A/S

Recruiting

TransCon (TC) TLR7/8 Agonist, TC IL-2 β/γ, Pembrolizumab Prior to Surgery for Advanced Head and Neck Squamous Cell Carcinoma (BelieveIT-201)

Head and Neck Neoplasms

United States, Spain, Georgia, Hungary, Germany, Italy, Taiwan
Fifth Affiliated Hospital, Sun Yat-Sen University

Recruiting

The Efficacy and Safety of De-escalated Postoperative Radiotherapy in Locally Advanced HNSCC With pCR/MPR

Head and Neck Squamous Cell Carcinoma

China
M.D. Anderson Cancer Center

Recruiting

3-5 FrAction Stereotactic Body Radiation Therapy for Palliation of Head and Neck Squamous Cell Carcinoma: the FAST Phase II Randomized Trial

Head and Neck Squamous Cell Carcinoma

United States
Assiut University

Not yet recruiting

Effect of Accelerated RTH in Squamous Cell Carcinoma in Head and Neck

Head and Neck Squamous Cell Carcinoma
Chongqing University Cancer Hospital

Recruiting

The Efficacy of Induction and Adjuvant Camrelizumab Combined With Chemoradiation for LA-HNSCC

Head and Neck Squamous Cell Carcinoma

China
Thomas Jefferson University

Recruiting

Virtual Reality 3D-Surgery Modeling to Enhance Head and Neck Cancer Surgery Quality

Head and Neck Squamous Cell Carcinoma

United States
Gruppo Oncologico del Nord-Ovest

Recruiting

Induction and Maintenance Treatment With PARP Inhibitor and Immunotherapy in HPV-negative HNSCC (PRIME)

Head and Neck Squamous Cell Carcinoma

Italy
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Adjuvant Immunotherapy After Salvage Surgery in Head and Neck Squamous Cell Carcinoma (ADJORL1)

Head and Neck Squamous Cell Carcinoma

France
M.D. Anderson Cancer Center
Dana-Farber Cancer Institute

Active, not recruiting

Paclitaxel, Carboplatin and Cetuximab (PCC) With Cetuximab, Docetaxel, Cisplatin and Fluorouracil (C-TPF) in Previously Untreated Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma

United States
Baylor College of Medicine

Completed

Phase I/II Study OF Metformin in Combination With Cisplatin and Radiation in Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma

United States
National Taiwan University Hospital
Novartis

Active, not recruiting

Ribociclib and Spartalizumab in R/M HNSCC (RISE-HN)

Head and Neck Squamous Cell Carcinoma

Taiwan
University of Illinois at Urbana-Champaign
Augusta Victoria Hospital, East Jerusalem

Completed

Feasibility of a Carbohydrate-restricted, High-fat Diet on Head and Neck Squamous Cell Carcinoma Outcomes (CRHF)

Head and Neck Squamous Cell Carcinoma

Palestinian Territory, occupied
Institut du Cancer de Montpellier - Val d'Aurelle

Active, not recruiting

Efficacy of an Oral Immunomodulatory Nutrient on Survival During Postoperative Concomitant Chemoradiotherapy in Head and Neck Cancer (SIMPA01)

Head and Neck Squamous Cell Carcinoma

France
Centre Henri Becquerel

Unknown

Detection of Circulating Tumor DNA in p16- Locally Advanced Head Neck Squamous Cell Carcinoma (PERSO-NECK)

Head and Neck Squamous Cell Carcinoma

France
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Institute of Dental and Craniofacial Research (NIDCR)

Completed

A Phase II Trial of Tadalafil in Patients With Squamous Cell Carcinoma of the Upper Aero Digestive Tract

Head and Neck Squamous Cell Carcinoma

United States
University of Michigan Rogel Cancer Center

Withdrawn

A Phase II Trial Evaluating WNT974 in Patients With Metastatic Head and Neck Squamous Cell Carcinoma

Squamous Cell Carcinoma, Head And Neck

United States
Lithuanian University of Health Sciences

Completed

Assessing Tumor Response and IMRT Treat Plan After IC Based on FDG-PET/CT for Locally Advanced HNSCC

Head and Neck Squamous Cell Carcinoma

Lithuania
Sinocelltech Ltd.

Recruiting

SCT200 in Combination With SCT-I10A/Paclitaxel/Docetaxel in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Carcinoma

China
GlaxoSmithKline

Recruiting

A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma (JADE)

Neoplasms, Head and Neck

United States, Italy, Japan, Norway, Spain, Taiwan, Australia, United Kingdom, Belgium, Brazil, Germany, Greece, Romania, Sweden, Turkey, Canada, Korea, Republic of, China, France, Argentina, India, Poland, Israel, Portugal, Mexico, Czechia, Hunga...
Lund University Hospital

Recruiting

a Multicentre Phase III Study of Risk-based Treatment Intensification With Hyperfractionated Radiotherapy in Head and Neck Cancer Patients (ARTSCAN VI)

Head and Neck Squamous Cell Carcinoma

Sweden
Tianjin Medical University Cancer Institute and...

Recruiting

A Single-center Phase II Study to Investigate the Immune Maintenance Therapy Pattern in Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma Who Have Achieved MPR After Neoadjuvant Immunotherapy Combined With Chemotherapy

Head and Neck Cancer

China
ALX Oncology Inc.
Merck Sharp & Dohme LLC

Recruiting

Evorpacept (ALX148) in Combination With Pembrolizumab in Patients With Advanced Head and Neck Squamous Cell Carcinoma (ASPEN-03)

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma

United States, Korea, Republic of, United Kingdom, Spain, Belgium, Singapore, Canada, Netherlands, Australia
M.D. Anderson Cancer Center

Active, not recruiting

A Pilot Study of Glutamine PET Imaging of Head and Neck Squamous Cell Carcinoma

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma

United States
Case Comprehensive Cancer Center

Completed

Temporally Feathered Radiation Therapy (TFRT) for Head and Neck Squamous Cell Carcinoma

Head and Neck Cancer

United States
Massachusetts General Hospital
Merck Sharp & Dohme LLC; AperiSys, Inc

Withdrawn

AMD3100 Plus Pembrolizumab in Immune Checkpoint Blockade Refractory Head and Neck Squamous Cell Carcinoma

Head and Neck Cancer

United States
Hoffmann-La Roche

Completed

A Study of Pharmacodynamics of RO5083945 in Patients With Head and Neck Squamous Cell Carcinoma

Head and Neck Cancer

Spain, France, United Kingdom, Netherlands, Italy
Seoul National University Hospital
Clinical Research Center for Solid Tumor, Korea

Completed

Cetuximab as Induction Treatment in Head and Neck Squamous Cell Carcinoma (HNSCC)

Head and Neck Neoplasm

Korea, Republic of
All India Institute of Medical Sciences, New Delhi

Unknown

Accelerated Fractionation Radiotherapy (AFRT) Versus Concurrent Chemoradiotherapy (Crt) In Locally Advanced Head And Neck Squamous Cell Carcinoma

HEAD AND NECK CANCER

India
Cascadian Therapeutics Inc.

Completed

Study of PX-866 and Docetaxel in Solid Tumors

Non Small Cell Lung Cancer (NSCLC) | Squamous Cell Carcinoma of the Head and Neck (SCCHN)

United States, Canada
Memorial Sloan Kettering Cancer Center
Celgene Corporation; National Comprehensive Cancer Network

Completed

Weekly Nanoparticle Albumin-Bound Paclitaxel (Abraxane) + Weekly Cetuximab + Radiation Therapy (IMRT, Intensity-Modulated Radiation Therapy) in Patients With Stage III-IVB Head and Neck Squamous Cell Carcinoma (HNSCC)

HEAD & NECK Cancer

United States
The Netherlands Cancer Institute

Completed

ctDNA as a Biomarker for Treatment Response in HNSCC (PECAN)

Carcinoma, Squamous Cell of Head and Neck

Netherlands
Washington University School of Medicine
Pfizer

Completed

PD 0332991 and Cetuximab in Patients With Incurable SCCHN

Carcinoma, Squamous Cell of Head and Neck

United States
The Netherlands Cancer Institute
Merck KGaA, Darmstadt, Germany

Completed

Bioimmunoradiotherapy (Cetuximab/RT/Avelumab)

Carcinoma, Squamous Cell of Head and Neck

Netherlands
Daping Hospital and the Research Institute of Surgery...

Unknown

Concurrent Chemoradiotherapy(CRT) in Locally Advanced(LA) SCCHN vs Cetuximab With Radiotherapy (RT) After Neoadjuvant Chemotherapy

Carcinoma, Squamous Cell of Head and Neck
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Not yet recruiting

Testing the Addition of an Investigational Drug, Xevinapant, to Usual Radiation Therapy Plus Cisplatin/Carboplatin for Patients With Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma | Oropharyngeal Squamous Cell Carcinoma | Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III... and other conditions
Shyam S.D. Rao
National Cancer Institute (NCI)

Recruiting

Losartan, Pembrolizumab and Stereotactic Body Radiation Therapy for the Treatment of Patients With Locally Recurrent, Refractory or Oligometastatic Head and Neck Squamous Cell Carcinoma

Metastatic Head and Neck Squamous Cell Carcinoma | Locally Recurrent Head and Neck Squamous Cell Carcinoma | Refractory Head and Neck Squamous Cell Carcinoma

United States
CureVac
Syneos Health; Cromos Pharma LLC

Active, not recruiting

Study of Intratumoral CV8102 in cMEL, cSCC, hnSCC, and ACC

Carcinoma, Adenoid Cystic | Melanoma (Skin) | Squamous Cell Carcinoma of the Skin | Carcinoma, Squamous Cell of Head and Neck

Spain, France, Austria, Germany, Russian Federation
Inovio Pharmaceuticals
University of Pennsylvania

Completed

Study of HPV Specific Immunotherapy in Participants With HPV Associated Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Cancer

United States
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Completed

Gefitinib, Paclitaxel, and Radiation Therapy in Treating Patients With Advanced or Recurrent Squamous Cell Carcinoma of the Head and Neck

Head and Neck Cancer

United States
Grupo Español de Tratamiento de Tumores de Cabeza...
Bristol-Myers Squibb; Apices Soluciones S.L.

Active, not recruiting

Study to Assess the Efficacy and Safety of Nivolumab in Combination With Paclitaxel in Subjects With Head and Neck Cancer Unable for Cisplatin-based Chemotherapy (NIVOTAX) (NIVOTAX)

Recurrent Head and Neck Squamous Cell Carcinoma | Head and Neck Cancer Stage IV

Spain
Heidelberg University
University Hospital Heidelberg

Terminated

TPF Followed by Cetuximab and IMRT Plus Carbon Ion Boost for Locally Advanced Head and Neck Tumors (TPF-C-HIT)

Locally Advanced Squamous Cell Carcinoma of the Head and Neck (SCCHN): Oro-, Hypopharyngeal and Laryngeal Cancer

Germany
The First Affiliated Hospital of Soochow University
Biotech Pharmaceutical Co., Ltd.; Cinda Biopharmaceutical (Suzhou) Co., Ltd.

Not yet recruiting

Sintilimab and Nimotuzumab Combined With Chemotherapy for the Treatment of R/M HNSCC. (Carpp-1)

Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
RTOG Foundation, Inc.
Merck Sharp & Dohme LLC

Recruiting

SBRT +/- Pembrolizumab in Patients With Local-Regionally Recurrent or Second Primary Head and Neck Carcinoma (KEYSTROKE)

Head and Neck Squamous Cell Carcinoma (HNSCC)

Canada, United States
Washington University School of Medicine
Bristol-Myers Squibb

Active, not recruiting

Nab-Paclitaxel in Combination With Nivolumab to Treat Recurrent or Metastatic Head and Neck Squamous-Cell Carcinoma That Progressed on a PD-1 or PD-L1 Inhibitor

Metastatic Head-and-neck Squamous-cell Carcinoma

United States
West Virginia University
West Virginia Clinical and Translational Science Institute

Terminated

Pilot Study of Metformin in HNSCC to Investigate the Effects of MF, Tumor Genotype and MF-genotype Interactions, on Tumor Metabolism and Anoikis

Cancer of Head and Neck

United States
Ohio State University Comprehensive Cancer Center
National Comprehensive Cancer Network

Completed

Ph I Vorinostat in the Treatment of Advanced Staged Oropharyngeal Squamous Cell Carcinoma

Stage III Squamous Cell Carcinoma of the Oropharynx | Stage IV Squamous Cell Carcinoma of the Oropharynx

United States
Royal Marsden NHS Foundation Trust

Completed

A Phase II Study of Parotid-gland Sparing IMRT in Patients With Midline Tumour of the Head and Neck (PARSPORT-II)

Oropharyngeal Squamous Cell Cancer | Hypopharyngeal Squamous Cell Cancer

United Kingdom
Stanford University
AstraZeneca; American Society of Clinical Oncology

Completed

Cisplatin and ZD1839 + Re-Irradiation in Recurrent Squamous Cell Cancer of the Head and Neck

Head and Neck Cancer | Carcinoma, Squamous Cell

United States

Clinical Trials on Cutaneous Squamous Cell Carcinoma of the Head and Neck

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