Clinical Trials on Cystic Fibrosis Related Diabetes

Total 22336 results

University Hospital, Lille

Completed

Prognostic Value of Functional Exercise Test (EFX) in Cystic Fibrosis (EFX)

Cystic Fibrosis

France
Nabriva Therapeutics AG

Completed

Study to Assess the Safety and PK of Oral and IV Xenleta in Adults With Cystic Fibrosis

Cystic Fibrosis

United States
Vertex Pharmaceuticals Incorporated

Completed

Safety and Pharmacokinetic Study of Lumacaftor/Ivacaftor in Participants 1 to Less Than 2 Years of Age With Cystic Fibrosis, Homozygous for F508del

Cystic Fibrosis

United States, Canada
University of Washington
Cystic Fibrosis Foundation

Completed

A Pharmacokinetic and Safety Study of IV Gallium Nitrate (Ganite) in Cystic Fibrosis Patients

Cystic Fibrosis

United States
University of Alabama at Birmingham
Cystic Fibrosis Foundation

Completed

Clinical Effort Against Smoke Exposure in Cystic Fibrosis (CEASE-CF)

Cystic Fibrosis

United States
Vertex Pharmaceuticals Incorporated

Completed

A Study Evaluating Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor in Subjects 6 Through 11 Years of Age With Cystic Fibrosis and F/MF Genotypes

Cystic Fibrosis

Canada, France, Germany, United Kingdom, Israel, Australia, Spain, Netherlands, Denmark, Switzerland
AlgiPharma AS
Imperial College London; Cystic Fibrosis Foundation; University Hospital of Cologne and other collaborators

Withdrawn

A Dose-finding Study of Inhaled OligoG vs Placebo in Patients With Cystic Fibrosis (SMR3372)

Cystic Fibrosis

Germany
National Jewish Health

Completed

Phase II Study of Digitoxin to Treat Cystic Fibrosis

Cystic Fibrosis

United States
Mylan Inc.

Completed

Human Factors Study to Validate the User Interface of TOBI Podhaler Using Placebo Capsules

Cystic Fibrosis

United States
Vertex Pharmaceuticals Incorporated

Terminated

A Study Evaluating the Long Term Safety and Efficacy of VX-659 Combination Therapy

Cystic Fibrosis

United States, Spain, Ireland, Australia, Israel, United Kingdom, Germany, Canada, Denmark, Poland, Switzerland
Vertex Pharmaceuticals Incorporated

Completed

A Decentralized Study to Evaluate Physical Activity and Cough Frequency Using Wearable Technology in Cystic Fibrosis

Cystic Fibrosis

United States, United Kingdom
Vertex Pharmaceuticals Incorporated

Completed

A Study of VX-445 in Healthy Subjects and Subjects With Cystic Fibrosis

Cystic Fibrosis

United States, Australia, Belgium, Netherlands
Assistance Publique - Hôpitaux de Paris
Societe Francaise de la Mucoviscidose; Effi-Stat

Completed

Real-life Follow-up of Cystic Fibrosis Patients Treated With Ivacaftor+Lumacaftor (Orkambi*) (ORKAMBI)

Cystic Fibrosis

France
Royal Brompton & Harefield NHS Foundation Trust
National Institute for Health Research, United Kingdom

Completed

Improving Outcome Measures For Adult CF ACT Trials

Cystic Fibrosis

United Kingdom
Vertex Pharmaceuticals Incorporated

Completed

Evaluation of VX 445/TEZ/IVA in Cystic Fibrosis Subjects 6 Through 11 Years of Age

Cystic Fibrosis

United States, Canada, Australia, Ireland, United Kingdom
Santhera Pharmaceuticals

Completed

Clinical Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of POL6014 in Patients With CF

Cystic Fibrosis

Germany
University Hospital, Lille

Terminated

Evaluation of Short Antibiotic Combination Courses Followed by Aerosols in Cystic Fibrosis (TOBRAMUC)

Cystic Fibrosis

France
Parion Sciences
Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate the Safety and Efficacy of VX-371 in Subjects With Cystic Fibrosis Who Are Homozygous for the F508del-CFTR Mutation

Cystic Fibrosis

United Kingdom, United States, France, Ireland
Hospices Civils de Lyon

Completed

Cystic Fibrosis Adherence Study (KINOBS)

Cystic Fibrosis

France
Parion Sciences
Vertex Pharmaceuticals Incorporated

Completed

Clearing Lungs With Epithelial Sodium Channel (ENaC) Inhibition in Cystic Fibrosis (CF) (CLEAN-CF)

Cystic Fibrosis

United States
Boston Children's Hospital

Completed

Clinical Utility of the 1-minute Sit to Stand Test as a Measure of Submaximal Exercise Tolerance in Patients With Cystic Fibrosis During Acute Pulmonary Exacerbation

Cystic Fibrosis

United States
Vertex Pharmaceuticals Incorporated

Completed

A Phase 3 Study of VX-445 Combination Therapy in Cystic Fibrosis (CF) Subjects Heterozygous for F508del and a Gating or Residual Function Mutation (F/G and F/RF Genotypes)

Cystic Fibrosis

United States, Spain, Ireland, Belgium, Netherlands, United Kingdom, Australia, France, Canada, Denmark, Germany, Italy, Israel
Steven M Rowe

Completed

G551D Observational Study- Expanded to Additional Genotypes and Extended for Long Therm Follow up (GOAL-e2) (GOAL- e2)

Cystic Fibrosis

United States
Boehringer Ingelheim

Terminated

A 4-week Study to Test Different Doses of BI 1265162 in Adolescents and Adults With Cystic Fibrosis Using the Respimat® Inhaler - BALANCE - CF™1

Cystic Fibrosis

United States, Spain, Belgium, Germany, Canada, United Kingdom, Sweden, France
Rush University Medical Center

Completed

Efficacy of TOBI Podhaler vs. Tobramycin Inhalation Solution (PETIS)

Cystic Fibrosis

United States
NovaBiotics Ltd.
Agility Clinical, Inc.; PSR Group B.V.

Completed

A Study of the Dosing, Efficacy, and Safety of Oral Cysteamine in Adult Patients With Cystic Fibrosis Exacerbations (CARE-CF1)

Cystic Fibrosis

United States, United Kingdom, Italy
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Evaluation of a Behavioural Intervention Using App Technology in CF (EAT-CF)

Cystic Fibrosis

United Kingdom
University of Colorado, Denver
Cystic Fibrosis Foundation; Colorado Clinical & Translational Sciences Institute

Completed

Improving Treatment of Nontuberculous Mycobacterial Infection in Cystic Fibrosis

Cystic Fibrosis

United States
Carmel Medical Center

Completed

Real Life Evaluation of the Multi-organ Effects of Lumacaftor/Ivacaftor on F508del Homozygous Cystic Fibrosis Patients.

Cystic Fibrosis
Novartis Pharmaceuticals

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QAU145 in Patients With Cystic Fibrosis

Cystic Fibrosis

United States
Liminal BioSciences Ltd.

Terminated

Study of Safety, Tolerability & Efficacy in Cystic Fibrosis Patients With Abnormal Glucose Tolerance

Cystic Fibrosis

Canada
University of Miami
University of Alabama at Birmingham; University of Kansas Medical Center; Children... and other collaborators

Terminated

Losartan and Inflammation in Cystic Fibrosis

Cystic Fibrosis

United States
Pharmaxis
ethica Clinical Research Inc.; Europe: KasaConsult bvba, Hoegaarden, Belgium; Argentina: Resolution Latin America; Buenos Aires, Argentina

Completed

Long Term Administration of Inhaled Mannitol in Cystic Fibrosis

Cystic Fibrosis

United States, France, Belgium, Canada, Argentina, Germany, Netherlands
MemorialCare Health System
University of California, Irvine

Completed

Impact of Telerehabilitation Training on Pediatric Cystic Fibrosis Patients: An Exploratory Study

Cystic Fibrosis

United States
Hannover Medical School
Heidelberg University; University of Giessen

Completed

ICM to Evaluate the Activation of p.Phe508del-CFTR by Lumacaftor in Combination With Ivacaftor (OrkambiFacts)

Cystic Fibrosis

Germany
Insmed Incorporated

Completed

Multidose Safety and Tolerability Study of Dose Escalation of Liposomal Amikacin for Inhalation (ARIKACE™)

Cystic Fibrosis

Poland, Ukraine, Serbia, Belgium, Hungary, Slovakia, North Macedonia
AO GENERIUM

Completed

Efficacy and Safety of Tigerase® vs. Pulmozyme® in Patients With Cystic Fibrosis

Fibrosis | Cystic Fibrosis

Russian Federation
University Hospital, Bordeaux

Unknown

Polyethylene Glycol and Intestinal Inflammation in Cystic Fibrosis (MUCOLAX)

Cystic Fibrosis
Koronis Biomedical Technologies
Johns Hopkins University

Unknown

Cystic Fibrosis Remote Monitoring System

Cystic Fibrosis
University of Alabama at Birmingham
Cystic Fibrosis Foundation

Completed

A Two-Part Multicenter Prospective Longitudinal Study of CFTR-dependent Disease Profiling in Cystic Fibrosis (PROSPECT) (PROSPECT)

Cystic Fibrosis

United States
Vertex Pharmaceuticals Incorporated

Completed

A Phase 3 Study of VX-445 Combination Therapy in Subjects With Cystic Fibrosis Heterozygous for the F508del Mutation and a Minimal Function Mutation (F/MF)

Cystic Fibrosis

United States, Belgium, Netherlands, United Kingdom, Canada, Germany, Australia, France, Italy, Czechia, Austria, Greece, Sweden
PTC Therapeutics
Cystic Fibrosis Foundation; ECFS-Clinical Trial Network (ECFS-CTN)

Completed

Study of Ataluren in Nonsense Mutation Cystic Fibrosis (ACT CF)

Cystic Fibrosis

United States, Spain, United Kingdom, Netherlands, Germany, France, Belgium, Italy, Australia, Argentina, Brazil, Bulgaria, Canada, Greece, Israel, Poland
Proteostasis Therapeutics, Inc.

Completed

Safety, Tolerability, and Pharmacokinetics of PTI-808, PTI-801, and PTI-428 Combination Therapy in Subjects With Cystic Fibrosis

Cystic Fibrosis

United Kingdom
Proteostasis Therapeutics, Inc.

Completed

Study Assessing PTI-428 Safety, Tolerability, and Pharmacokinetics in Subjects With Cystic Fibrosis on KALYDECO® as Background Therapy

Cystic Fibrosis

United Kingdom
King's College Hospital NHS Trust
King's College London

Completed

LBM & Lung Function in Adolescents With CF

Cystic Fibrosis

United Kingdom
Queen Mary University of London

Completed

Air Pollution and Children With Cystic Fibrosis

Cystic Fibrosis

United Kingdom
University Hospital, Montpellier

Completed

Educational Program Through Video Conference for Inhaled Therapies in Cystic Fibrosis Patients (Visio-Respir)

Cystic Fibrosis

France
Pontificia Universidade Católica do Rio Grande...

Completed

Interactive Video Game Responses in Cystic Fibrosis (Igamecf)

Cystic Fibrosis

Brazil
Children's Hospital of Philadelphia

Completed

Nasal Potential Difference (NPD) for the Diagnosis of Cystic Fibrosis

Cystic Fibrosis

United States
Imperial College London
University of Pennsylvania; University of Oxford; University of Edinburgh; Royal... and other collaborators

Completed

Single Dose of pGM169/GL67A in CF Patients

Cystic Fibrosis

United Kingdom

Clinical Trials on Cystic Fibrosis Related Diabetes

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