Clinical Trials on Cytomegalovirus Infections, Heart Transplantation in Canada

Total 188 results

Hoffmann-La Roche

Completed

A Study on the Pharmacokinetics and Safety of Valcyte (Valganciclovir) in Pediatric Heart Transplant Recipients Less Than 4 Months of Age

Cytomegalovirus Infections, Heart Transplantation

Spain, United States, Canada
Astellas Pharma Global Development, Inc.
Vical

Completed

A Study to Evaluate the Efficacy and Safety of a Vaccine, ASP0113, in Cytomegalovirus (CMV)-Seronegative Kidney Transplant Recipients Receiving an Organ From a CMV-Seropositive Donor

Kidney Transplantation Cytomegalovirus (CMV) Negative Recipients

United States, Australia, Canada, France, Germany, Spain
University of Alberta

Completed

Quantiferon - Cytomegalovirus (CMV) and the Prediction of CMV Infection In High Risk Solid Organ Transplant Recipients

Cytomegalovirus Infection

Canada
University of Alberta

Completed

Cytomegalovirus (CMV) MicroRNA Expression in Vivo and Immune Evasion Correlates

Transplant

Canada
University Health Network, Toronto
Canadian National Transplant Research Program

Completed

Cell-Mediated Immunity Based Primary Prophylaxis for CMV Infection in Organ Transplant Recipients (QFT-CMV)

Cytomegalovirus Viraemia

Spain, Canada
University Health Network, Toronto
The Physicians' Services Incorporated Foundation

Completed

Cell Mediated Immunity and the Prediction of CMV Infection In Solid Organ Transplant Recipients

Transplant

Canada
VBI Vaccines Inc.
Clinical Trial Data Services, LLC

Completed

Study to Evaluate Safety, Tolerability, and Immunogenicity of Candidate Human Cytomegalovirus Vaccine in Healthy Adults

Cytomegalovirus Infections

Canada
ModernaTX, Inc.

Active, not recruiting

A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus (CMV) Vaccine in Healthy Participants 16 to 40 Years of Age

Cytomegalovirus Infection

United States, Australia, Canada, France, Belgium, Germany, Israel, Italy, United Kingdom, Spain, Estonia, Finland, Japan
The Hospital for Sick Children

Completed

Pharmacogenetic Trial of Tacrolimus After Pediatric Transplantation

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Canada
National Institute of Allergy and Infectious Diseases...
Rho Federal Systems Division, Inc.; Clinical Trials in Organ Transplantation

Completed

PREDICT Cytomegalovirus (CMV) (PREDICT CMV)

Lung Transplant

United States, Canada
Hoffmann-La Roche

Completed

A Study of the Safety and Tolerance of Long-Term Therapy With Intravenous Cytovene (Ganciclovir Sodium) for Cytomegalovirus Retinitis in Persons With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States, Canada
Takeda

Completed

A Study on Cytomegalovirus (CMV) Infection Outcomes Among Hematopoietic Stem Cell Transplant (HSCT) Participants in Europe and Canada

Cytomegalovirus (CMV)

Belgium, Israel, Canada, Serbia, Austria, Greece, Poland
Takeda

Completed

A Study on Cytomegalovirus (CMV) Infection Outcomes Among Solid Organ Transplant (SOT) Participants in Europe and Canada

Cytomegalovirus (CMV)

Belgium, Israel, Austria, Canada, Greece, Italy, Netherlands, Poland, Sweden
University of Alberta

Recruiting

Breakthrough CMV Lung Transplant -Multicentre

Cytomegalovirus Infections

Canada
Merck Sharp & Dohme LLC

Completed

V160 2-Dose and 3-Dose Regimens in Healthy Cytomegalovirus (CMV) Seronegative Females (V160-002)

Cytomegalovirus (CMV) Infections

United States, Australia, Canada, Finland, Israel, Russian Federation, Spain
Astellas Pharma Global Development, Inc.

Completed

A Study to Evaluate a Therapeutic Vaccine, ASP0113, in Cytomegalovirus (CMV)-Seropositive Recipients Undergoing Allogeneic, Hematopoietic Cell Transplant (HCT) (HELIOS)

Cytomegalovirus (CMV)-Positive Recipients | Allogeneic, Hematopoietic Cell Transplant (HCT)

Japan, Korea, Republic of, United States, Canada, Australia, Belgium, France, Germany, Spain, Sweden, Taiwan
University of British Columbia
Vancouver Coastal Health Research Institute

Completed

Prevention of Healthcare Associated Infections in Bone Marrow Transplant Patients

Transplantation Infection

Canada
Shire
Takeda Development Center Americas, Inc.

Completed

A Study of Maribavir Compared to Valganciclovir to Treat Cytomegalovirus Infections in People Who Have Received Stem Cell Transplants

Cytomegalovirus (CMV)

United States, China, Spain, Belgium, Australia, Germany, Italy, Canada, France, Croatia, Singapore, United Kingdom, New Zealand, Korea, Republic of, Russian Federation, Poland, Austria, Greece, Switzerland, Czechia, Hungary, Israel, Turk...
Hoffmann-La Roche

Completed

A Randomized Controlled Study of the Efficacy and Safety of Maintenance Treatment With Oral Ganciclovir for Newly Diagnosed Cytomegalovirus Retinitis in People With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States, Canada
Shire

Completed

Efficacy and Safety Study of Maribavir Treatment Compared to Investigator-assigned Treatment in Transplant Recipients With Cytomegalovirus (CMV) Infections That Are Refractory or Resistant to Treatment With Ganciclovir, Valganciclovir, Foscarnet, or Cidofovir

Cytomegalovirus (CMV)

United States, Italy, France, Spain, Australia, Germany, Canada, United Kingdom, Belgium, Croatia, Austria, Denmark, Singapore, Switzerland
Hoffmann-La Roche

Completed

A Comparison of Valganciclovir and Ganciclovir in the Treatment of Cytomegalovirus (CMV) of the Eyes

HIV Infections | Cytomegalovirus Retinitis

United States, Canada
Hoffmann-La Roche

Completed

A Randomized Study Comparing the Safety and Efficacy of Two Regimens of Oral Ganciclovir to Intravenous Ganciclovir Maintenance Therapy for Cytomegalovirus Retinitis in People With AIDS Who Have Received Prior Ganciclovir Therapy

HIV Infections | Cytomegalovirus Retinitis

United States, Canada
The Hospital for Sick Children

Completed

The Safety of Oka Varicella in Children Prior to Solid Organ Transplantation

Organ Transplantation | Immunosuppression

Canada
University of British Columbia

Completed

Prevalence of Cytomegalovirus Infection in Patients With Quiescent Ulcerative Colitis (PROVE-UC)

Ulcerative Colitis | Cytomegalovirus Infections

Canada
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Enteric-coated Mycophenolate Sodium (EC-MPS) in Comparison to Mycophenolate Mofetil (MMF) in de Nove Heart Patients

Heart Transplantation

United States, Australia, Argentina, Canada
Grupo de Estudio de Infecciones en Transplantados
Merck Sharp & Dohme LLC

Unknown

Prophylaxis With Caspofungin in High-Risk Liver Transplantation

Liver Transplantation | Fungal Infection

Spain
Ramesh Prasad
Hoffmann-La Roche

Terminated

Mycophenolate Mofetil for Reducing Cardiovascular Risk in Renal Transplant Recipients (MMCR)

Cardiovascular Diseases | Kidney Transplantation

Canada
Nova Scotia Health Authority

Recruiting

Advanced Cardiac Imaging in Cardiac Allograft Vasculopathy

Heart Transplantation

Canada
University Health Network, Toronto

Completed

Cell Mediated Immunity for Secondary Prophylaxis in CMV SOT Patients (Q-CMV)

Cytomegalovirus Viraemia

Canada
Roche Global Development

Completed

A Study of Two Forms of Ganciclovir in the Treatment of Cytomegalovirus (CMV) of the Eyes in Patients With AIDS

HIV Infections | Cytomegalovirus Retinitis

United States, Canada
Hoffmann-La Roche

Completed

A Study of Valcyte (Valganciclovir) Syrup Formulation in Pediatric Solid Organ Transplant Recipients

Cytomegalovirus Infections

Spain, France, Germany, Mexico, United States, Australia, Canada
Astellas Pharma Europe Ltd.

Completed

Study to Ascertain if Prolonged Release Tacrolimus (FK506E - MR4) is Safe and Effective When Used in the Long Term and in Combination With Other Immunosuppressive Drugs in Patients Who Have Received a Transplant

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Spain, Australia, France, Germany, Canada, Italy, United Kingdom, Belgium, South Africa, Switzerland, Sweden, United States, Austria, Brazil, Czechia, Denmark, Finland, Hungary, Ireland, Mexico, Netherlands, New Zealand, Poland
National Institute of Allergy and Infectious Diseases...
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Alloantibodies in Pediatric Heart Transplantation

Pediatric Heart Transplantation | Pediatric Heart Transplant Recipients

United States, Canada
University Health Network, Toronto

Completed

Planned Semi-Elective Lung Tx Study

Lung Transplantation

Austria, Canada, Spain
Centre hospitalier de l'Université de Montréal...

Recruiting

Timing of Glaucoma Drainage Device With Boston Keratoprosthesis (GDD-KPro)

Glaucoma | Corneal Transplantation

Canada
University Health Network, Toronto
Apple Inc.

Recruiting

Apple-CPET Ted Rogers Understanding Exacerbations of Heart Failure (TRUE-HF)

Heart Failure | Heart Transplantation | Heart Failure, Diastolic | Heart Failure, Systolic | Heart Failure，Congestive

Canada
Hoffmann-La Roche

Completed

VICTOR Study - A Study of Valcyte (Valganciclovir po) Compared to Ganciclovir iv in Patients With Cytomegalovirus (CMV) Disease Who Are Solid Organ Transplant Recipients

Cytomegalovirus Infections

Spain, Australia, Ireland, India, Italy, Canada, Belgium, Switzerland, Estonia, Austria, United Kingdom, Brazil, Mexico, Norway, Latvia, Turkey, Croatia, Serbia, Poland, New Zealand, Venezuela
Novartis Pharmaceuticals

Completed

A Study of Safety, Tolerability & Efficacy of Certican in de Novo Heart Transplant (Tx) Patients

Heart Transplantation

Spain, United States, Austria, Italy, Canada, Germany, Australia, Brazil
Hoffmann-La Roche

Completed

A Study to Evaluate the Efficacy and Safety of Zenapax in Combination With CellCept, Cyclosporine, and Corticosteroids in Patients Undergoing Cardiac Transplantation

Heart Transplantation

United States, Canada, Germany, Sweden
National Institute of Allergy and Infectious Diseases...
Clinical Trials in Organ Transplantation in Children

Completed

Impact of Allo- and Autoantibodies on Chronic Cardiac Allograft Function

Pediatric Heart Transplantation | Pediatric Heart Transplant Recipients

United States, Canada
Hoffmann-La Roche

Completed

IMPACT Study: A Study of Valcyte (Valganciclovir) for Prevention of Cytomegalovirus Disease (CMV) in Kidney Allograft Recipients (IMPACT)

Cytomegalovirus Infections

United States, Belgium, United Kingdom, Canada, France, Spain, Brazil, Australia, Germany, Italy, Romania, New Zealand, Poland
Shire

Completed

Prophylactic Use of Maribavir for the Prevention of Cytomegalovirus (CMV) Disease in Stem Cell Transplant Recipients

Cytomegalovirus Infections

United States, Canada, United Kingdom, Germany, France, Belgium, Italy, Spain, Sweden
University Health Network, Toronto

Completed

Comparison of Quantiferon-TB Gold Assay With Tuberculin Skin Testing in Patients With Chronic Liver Disease

Liver Transplantation | Tuberculosis | Chronic Liver Disease

Canada
AlloVir

Terminated

Study of Posoleucel (ALVR105,Viralym-M) for Multi-Virus Prevention in Patients Post-Allogeneic Hematopoietic Cell Transplant (Prevent)

BK Virus Infection | Epstein-Barr Virus Infections | Cytomegalovirus Infections | Adenovirus Infection | JC Virus Infection | Human Herpes Virus-6 Infection

Korea, Republic of, United States, Spain, France, Turkey, Australia, United Kingdom, Italy, Canada, Belgium
University Health Network, Toronto

Completed

Improving the Humoral Response to Influenza Vaccine in Lung Transplant Recipients by an Intradermal Strategy

Lung Transplantation | Influenza Vaccines

Canada
University of Alberta

Not yet recruiting

Exercise MRI to Evaluate Cardiorespiratory Fitness in Children With Heart Disease

Heart Transplantation | Pediatric ALL | Congenital Heart Disease

Canada
Astellas Pharma Inc
Astellas Pharma Canada, Inc.

Completed

Canadian Cardiology de Novo Study: A Comparison Between Tacrolimus- and Cyclosporine- Based Immunoprophylactic Regimens

Heart Diseases | Heart Transplantation

Canada, United States
American Gastroenterological Association
University of Pennsylvania; University of California, San Diego; University of... and other collaborators

Recruiting

Fecal Microbiota Transplant National Registry (FMT)

Clostridium Difficile Infection | Gut Microbiome | Fecal Microbiota Transplantation

United States, Canada
University Health Network, Toronto

Unknown

FGL2/Fibroleukin and Hepatitis C Virus Recurrence Post Liver Transplantation

Liver Transplantation | Hepatitis C

Canada
Jordan Feld
University Health Network, Toronto

Recruiting

Transplantation Using Hepatitis C Positive Donors, A Safety Trial

Hepatitis C | Kidney Transplant Infection | Heart Transplant Infection | Lung Transplant Infection | Kidney Pancreas Infection

Canada

Clinical Trials on Cytomegalovirus Infections, Heart Transplantation in Canada

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