Clinical Trials on DDR Gene Mutation

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Lung Non-Small Cell Carcinoma | Stage IV Lung Cancer AJCC v8 | Health Care Provider | Activating ALK Gene Mutation Negative | Activating EGFR Gene Mutation Negative | Activating ROS1 Gene Mutation Negative

United States

Chronic Myelomonocytic Leukemia | Myeloproliferative Neoplasm | Acute Myeloid Leukemia With Gene Mutations | Myelodysplastic Syndrome With Gene Mutation

France

Pre-mutation on FMR1 Gene

France

Colorectal Cancer Metastatic | Brain Metastases, Adult | HER2 Gene Mutation | MSI | BRAF Gene Mutation | Ras (KRAS or NRAS) Gene Mutation

Russian Federation

Central Nervous System Neoplasms | Pediatric Cancer | Tumor, Brain | GEN1 Gene Mutation

Czechia

Non-Small Cell Lung Cancer | Non-squamous Non-small-cell Lung Cancer | Non-Squamous Non-Small Cell Neoplasm of Lung | KEAP1 Gene Mutation | NFE2L2 Gene Mutation | NRF2 Mutation

United States

Sensorineural Hearing Loss, Bilateral | Congenital Deafness | AUNB1 | DFNB1A | DFNB9 | OTOF Gene Mutation | GJB2 Gene Mutation

France

Glioma | Oligoastrocytoma | Anaplastic Astrocytoma | Oligodendroglioma | Diffuse Astrocytoma | WHO Grade III Glioma | IDH2 Gene Mutation | IDH1 Gene Mutation | 1p/19q Co-deletion

United States

Mendelian Disorders | Genetic Disorder | Novel Mutation | Hereditary Disorder | De Novo Mutation | Inherited Disease | Single-Gene Defects

United Arab Emirates

BRCA1 Mutation | BRCA2 Mutation | PALB2 Gene Mutation | Hormone Receptor Positive HER-2 Negative Breast Cancer | Advanced or Metastatic Breast Cancer

Germany

Pancreatic Ductal Adenocarcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Homologous Recombination Deficiency | Stage IIA Pancreatic Cancer AJCC v8 | Stage IIB Pancreatic Cancer AJCC v8 | ATM Gene Mutation | Deleterious BRCA1 Gene... and other conditions

Parkinson Disease | GBA Gene Mutation | Leucine-rich Repeat Kinase 2 (LRRK2) Gene Mutation

Israel

Genetic Predisposition | Gene Mutation-Related Cancer

Genetic Predisposition | Gene Mutation-Related Cancer

France, Guadeloupe, Martinique, Réunion

Acute Myeloid Leukemia | Relapsed Cancer | Refractory Cancer | IDH2 Gene Mutation

Canada

Isocitrate Dehydrogenase Gene Mutation

Spain, United States

Breast Cancer | Ovarian Cancer | BRCA1 Gene Mutation | BRCA2 Gene Mutation

Canada

CTNNB1 Gene Mutation | Hyperekplexia

France

Solid Tumor | APC Gene Mutation | AXIN1 Gene Mutation

United States

Breast Cancer | HER2 Gene Mutation

China

SMARCA4 Gene Mutation | DDX3X | 16P11.2 Deletion Syndrome | 16p11.2 Duplications | 1Q21.1 Deletion | 1Q21.1 Microduplication Syndrome (Disorder) | ACTL6B | ADNP | AHDC1 | ANK2 | ANKRD11 | ARID1B | ASH1L | BCL11A | CHAMP1 | CHD2 | CHD8 | CSNK2A1 | CTBP1 | CTNNB1 Gene Mutation | CUL3 | DNMT3A | DSCAM | DYRK1A | FOXP1 | GRIN2A | GRIN2B | HIVEP2-Related Intellectual... and other conditions

United States

Renal Failure | Solid Neoplasm | BRAF Gene Mutation | Hepatic Complication

United States, Canada

DDX41 Gene Mutation

France

Lung Cancer | Non-small Cell Lung Cancer | PD-L1 Gene Mutation | KRAS Activating Mutation

United States

Ameloblastoma | BRAF Gene Mutation

United States

Advanced or Metastatic Solid Tumors Irrespective of Gene Alterations | Advanced or Metastatic Solid Tumors With Germline PTEN Inactivating Mutations

United States, United Kingdom, Austria, France

Transitional Cell Carcinoma | Bladder Cancer | Urothelial Carcinoma | Metastatic Urothelial Carcinoma | FGFR2 Gene Mutation | FGFR3 Gene Mutation | FGFR2 Amplification | Bladder Urothelial Carcinoma | Locally Advanced Urothelial Carcinoma | Refractory Bladder Carcinoma | Refractory Bladder Urothelial Carcinoma and other conditions

United States

Stage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Recurrent Head and Neck Carcinoma | Recurrent Non-Small Cell Lung Carcinoma | Stage IV Non-Small Cell Lung Cancer | ALK Gene Mutation | EGFR Gene Mutation | Metastatic Head and Neck... and other conditions

United States

BRCA1 Gene Mutation | BRCA2 Gene Mutation | Castration-Resistant Prostate Carcinoma | Homologous Recombination Deficiency | PSA Progression | Stage IV Prostate Adenocarcinoma AJCC v7 | Castration Levels of Testosterone | ATM Gene Mutation | Prostate Carcinoma Metastatic in the Bone | PSA Level Greater...

United States

Biliary Tract Cancer | HER2 Gene Mutation

United States, Puerto Rico

HIV Infections | HIV-1-infection | PD-L1 Gene Mutation

China

ERα+ Breast Cancer | ESR1 Gene Mutation

United States

KRAS Gene Mutation | Infiltrating Urothelial Carcinoma

France

Diffuse Large B Cell Lymphoma | CD79A Gene Mutation | CD79B Gene Mutation

China

Cholangiocarcinoma | FGFR2 Gene Mutation | FGFR2 Fusion | FGFR1 Alteration | FGFR3 Alteration

United States

Obstructive Sleep Apnea Syndrome | Polycythemia Vera | Essential Thrombocythemia | CALR Gene Mutation | JAK2 Gene Mutation | MPL Gene Mutation

United States

Lung Neoplasms | EGFR Gene Mutation

Korea, Republic of

Non-Small Cell Lung Cancer | ALK Gene Mutation | EGFR Gene Mutation | BRAF V600E | Non-Small Cell Carcinoma of Lung, TNM Stage 4 | ROSE Cluster 1

United States

Biliary Tract Cancer | HER2 Gene Mutation

Germany

Melanoma | Colorectal Cancer | Solid Tumor | Non Small Cell Lung Cancer | Bladder Cancer | Thyroid Cancer, Papillary | Pilocytic Astrocytoma | Bladder Urothelial Carcinoma | Non-Small Cell Adenocarcinoma | MEK Mutation | RAS Mutation | Pancreatic Acinar Carcinoma | RAF Mutation | CRAF Gene Amplification | RAF1 Gene Amplification and other conditions

United States, Canada, Korea, Republic of, Spain, Australia, Belgium, France

Her-2 Negative Breast Cancer | HRR Gene Mutation

China

Metastatic Malignant Neoplasm | Advanced Malignant Neoplasm | Recurrent Malignant Neoplasm | Refractory Malignant Neoplasm | BRAF Gene Mutation

United States

NSCLC Stage IV | ALK Gene Mutation | ALK Sensitizing Mutation

Italy

Lung Cancer | ALK Gene Mutation | Resistance, Disease | Mutation

Denmark

Melanoma | BRAF Gene Mutation

United States

Melanoma | NRAS Gene Mutation | RAS Mutation

United States

Ovarian Cancer | BRCA1 Gene Mutation | BRCA2 Gene Mutation

Netherlands

Glioblastoma | Malignant Glioma | Recurrent Glioblastoma | Recurrent WHO Grade III Glioma | WHO Grade III Glioma | IDH2 Gene Mutation | IDH1 Gene Mutation | Low Grade Glioma | Recurrent WHO Grade II Glioma | WHO Grade II Glioma

United States

Gene Mutation | Epilepsy Idiopathic | Clinical Disease and/or Syndrome

China

Head and Neck Squamous Cell Carcinoma | Recurrent Head and Neck Carcinoma | Human Papillomavirus Infection | Recurrent Oropharyngeal Squamous Cell Carcinoma | FGFR Gene Amplification | FGFR1 Gene Amplification | FGFR2 Gene Amplification | FGFR2 Gene Mutation | FGFR3 Gene Mutation | Recurrent Nasopharynx...

United States