Clinical Trials on DNA

Total 23034 results

Asan Medical Center

Unknown

Compare Continuing Lamivudine Plus Adefovir or Adefovir Versus Switching to Entecavir Plus Adefovir in Patients With LAM-resistant Chronic Hepatitis B

Hepatitis B, Chronic

Korea, Republic of
Bristol-Myers Squibb

Completed

Dose Ranging Study of Pegylated Interferon Lambda in Patients With Hepatitis B and Positive for the Hepatitis B e Antigen (LIRA-B)

Hepatitis B Virus

Australia, France, Germany, Korea, Republic of, Taiwan, United States, Canada, Italy, Netherlands, Singapore, Hong Kong
Bristol-Myers Squibb

Completed

Persistence, Adherence and Clinical Effectiveness of Entecavir in Chronic Hepatitis B Patients

Hepatitis B, Chronic

Germany
Third Affiliated Hospital, Sun Yat-Sen University

Unknown

Entecavir Combined Short-term Intravenous Hepatitis B Immune Globulin (HBIG) to Prevent Hepatitis B Recurrence After Liver Transplantation

Liver Transplantation | Hepatitis B

China
Asian-Pacific Alliance of Liver Disease, Beijing
Beijing Ditan Hospital; National Health and Family Planning Commission, P.R... and other collaborators

Unknown

Emtricitabine for Naive Child Chinese Chronic Hepatitis B Patients

Hepatitis B, Chronic
Novartis Pharmaceuticals

Completed

A Single-arm Study Evaluating the Efficacy and Safety of Telbivudine With or Without add-on Tenofovir in Adults With HBeAg-positive Chronic Hepatitis B (CHB)

Hepatitis B, Chronic

Argentina, Brazil, Germany, Thailand
National University Hospital, Singapore

Unknown

Antigen-specific Immune Response to Hepatitis B Virus in Utero

Hepatitis B

Singapore
Bristol-Myers Squibb

Completed

Entecavir Plus Tenofovir Combination Therapy Versus Entecavir Monotherapy in Naive Subjects With Chronic Hepatitis B

Hepatitis B, Chronic

Australia, France, India, Italy, United States, Canada, Poland, Russian Federation, Argentina, South Africa, Brazil, Turkey, Mexico
Gangnam Severance Hospital
Roche Pharma AG

Unknown

HBsAg Related Response Guided Therapy (S-RGT)

Hepatitis B, Chronic

Korea, Republic of
Bausch Health Americas, Inc.

Completed

Dose-Ranging Study of Pradefovir in Patients With Compensated Hepatitis B

Hepatitis B, Chronic
Hanyang University
Roche Pharma AG

Unknown

Efficacy Study of Sequential Therapy of Peginterferon Alfa-2a Following Entecavir in Patient With Chronic Hepatitis B. (POTENT)

Hepatitis B, Chronic

Korea, Republic of
Pharmasset

Terminated

Efficacy and Safety of Clevudine Compared With Adefovir in Patients With Chronic Hepatitis Due to Hepatitis B Virus (QUASH2)

Hepatitis B | Chronic Hepatitis

United States, Canada, China, Argentina, Taiwan, Spain, Puerto Rico, Australia, Greece, Thailand, United Kingdom
Sun Yat-sen University

Unknown

Early Response to Interferon Combined Short-Term Nucleoside Analogue Therapy in HBeAg(+) Chronic Hepatitis B

Hepatitis B, Chronic

China
Stealth BioTherapeutics Inc.

Active, not recruiting

Study to Evaluate Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease From Nuclear DNA Mutations (nPMD) (NuPower)

Mitochondrial Diseases | Mitochondrial Myopathies | Mitochondrial Complex I Deficiency | Mitochondrial Pathology | Mitochondrial DNA Depletion | Mitochondrial DNA Mutation | Mitochondrial DNA Deletion | Mitochondrial Metabolism Defect

Spain, United States, Italy, Netherlands, Australia, Germany, Hungary, New Zealand, Norway, United Kingdom
Fondazione IRCCS Policlinico San Matteo di Pavia

Not yet recruiting

Risk of Reactivation of Occult Hepatitis B in Cancer Patients During Immunotherapy.

Occult Hepatitis B Infection in Cancer Patients

Italy
Shanghai Zhimeng Biopharma, Inc.
Tigermed Consulting Co., Ltd

Recruiting

A Study to Evaluate the Efficacy and Safety of ZM-H1505R in Combination With ETV Compared With ETV Monotherapy in Patients With CHB

Hepatitis B, Chronic

China
Third Affiliated Hospital, Sun Yat-Sen University

Recruiting

Nucleoside (Acid) Analogues Treatment in Patients With Normal ALT and Positive HBVDNA. (ALTHBV)

Hepatitis B Virus

China
The University of Hong Kong

Recruiting

Detecting Occult HBV Infection in Liver Donors Positive for Antibody to Hepatitis B Core Antigen (Anti-HBc) (OBI)

Liver Transplant; Complications | Occult Hepatitis B

Hong Kong
University Health Network, Toronto

Recruiting

Tenofovir Alafenamide With Fine Needle Aspiration Biopsy in Chronic Hepatitis B:

Hepatitis B, Chronic

Canada
Ottawa Hospital Research Institute

Recruiting

Ribavirin to Enhance Hepatitis B Virus Nucleotide Analog Antiviral Activity

Hepatitis B, Chronic

Canada
Janssen Pharmaceutica N.V., Belgium

Withdrawn

A Study in Chronic Hepatitis B e-Antigen Negative Participants After Discontinuation of Nucleos(t)Ide Analog (NA) Treatment (SALMONS)

Hepatitis B, Chronic

Germany, France, Italy, Spain, Denmark, Portugal, Greece
Hoffmann-La Roche

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of RO7049389 in Healthy Volunteers and Chronic Hepatitis B Virus (HBV) Infected Participants

Hepatitis B, Chronic

Australia, New Zealand, Singapore, Thailand, Taiwan, China, Bulgaria, Hong Kong
Alexion
Achillion, a wholly owned subsidiary of Alexion

Completed

Safety and Antiviral Activity Study of ACH-126,443 (Beta-L-Fd4C) in Treatment-naive Adults With Chronic Hepatitis B Virus Infection

Hepatitis B, Chronic

Bulgaria, Former Yugoslavia
F-star Therapeutics, Inc.
PRA Health Sciences

Terminated

Evaluating the Safety and Efficacy of Inarigivir in Non-cirrhotic Treatment Naive Subjects Infected With Hepatitis B Virus

Hepatitis B | Hepatitis B, Chronic | HBV

Hong Kong
Arrowhead Pharmaceuticals
ICON Clinical Research

Terminated

A Multicenter Study to Determine the Depth and Duration of Hepatitis B Surface Antigen (HBsAg) Reduction After Single or Multiple Doses of ARC-520, in Combination With Entecavir in Patients With Chronic Hepatitis B Virus (HBV) Infection

Hepatitis B, Chronic

Hong Kong
Dynavax Technologies Corporation

Completed

A Study to Assess DV-601 in Subjects With Chronic Hepatitis B

Hepatitis B, Chronic

Poland
Third Affiliated Hospital, Sun Yat-Sen University

Completed

The Safety of Anti-viral Therapy in Preventing HBV MTCT in Pregnant Women After Discontinuation

Hepatitis B, Chronic
Bristol-Myers Squibb

Completed

A Study of Entecavir in Pediatric Patients With Chronic Hepatitis B Virus (HBV)-Infection

Hepatitis B, Chronic

United States, Korea, Republic of, Taiwan, United Kingdom, Brazil, Argentina, Belgium, Canada
Enyo Pharma
PRA Health Sciences

Completed

EYP001a Food Effect Study in Subjects With Chronic Hepatitis B Virus (HBV) Infection

Hepatitis B, Chronic

Netherlands
Alios Biopharma Inc.

Withdrawn

A Study Evaluating AL-3778 in Combination With Peginterferon Alpha-2a in Chronic Hepatitis B Subjects

Hepatitis B, Chronic
Novartis

Completed

Prospective Exploratory Study to Evaluate the Safety and Efficacy of Telbivudine in the Fifth Year of Treatment in Chinese Patients With Compensated Chronic Hepatitis B

Hepatitis B, Chronic

China
Hoffmann-La Roche

Completed

A Study Evaluating IL28B Polymorphism in Patients With HBeAg-Negative Chronic Hepatitis B Treated With Pegasys (Peginterferon Alfa-2a) in Study ML18253

Hepatitis B, Chronic

Italy
Hoffmann-La Roche

Completed

A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Combination With Adefovir or Entecavir in Patients With HBeAg-Positive Chronic Hepatitis B

Hepatitis B, Chronic

Taiwan
Merck Sharp & Dohme LLC

Completed

PegIntron Treatment of Chronic Hepatitis B e Antigen-Positive Patients (P05170/MK-4031-327)

Hepatitis B, Chronic
Hoffmann-La Roche

Withdrawn

A Study of 48 Versus 96 Weeks of Peginterferon Alfa-2a [Pegasys] Treatment, With or Without Entecavir, in Patients With Chronic Hepatitis B.

Hepatitis B, Chronic
Hoffmann-La Roche

Completed

A Study of Pegylated Interferon Alfa-2a and Lamivudine in Patients With HBeAg-Negative Chronic Hepatitis B Virus (HBV)

Hepatitis B, Chronic

Italy
Hoffmann-La Roche

Completed

A Retrospective Biomarker Study of Stored Samples Obtained From Patients With Chronic Hepatitis B

Hepatitis B, Chronic

Hong Kong, Taiwan, Singapore, Korea, Republic of, New Zealand, France, Thailand, Russian Federation, Australia, Italy
Hoffmann-La Roche

Completed

A Study of PEGASYS (Peginterferon Alfa-2a [40KD]) in Patients With Hepatitis B e Antigen (HBeAg)-Negative Chronic Hepatitis B Virus (HBV)

Hepatitis B, Chronic

Bulgaria
Hoffmann-La Roche

Completed

ADVANCE Study: A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) + Adefovir Dipivoxil in Patients With Hbe(-) Chronic Hepatitis B

Hepatitis B, Chronic

Turkey
Nanfang Hospital of Southern Medical University
Novartis; Major Science and Technology Special Project of China Twelfth-Five-Year...

Unknown

EFFORT Further Extension Study

Hepatitis B, Chronic

China
Kyoto University

Completed

Activation of Hepatitis B Virus (HBV) in Hepatitis B Surface Antigen (HBsAg) - Negative But Hepatitis B Core Antibody (Anti-HBc) - Positive Patients

Hepatitis B

Japan
Pusan National University Hospital
Yonsei University

Completed

Continuing Lamivudine Versus Switching to Entecavir in Patients Who Achieved Undetectable Hepatitis B Virus DNA

Hepatitis B, Chronic

Korea, Republic of
Jiangsu Hansoh Pharmaceutical Co., Ltd.
Nanjing Medical University

Unknown

Phase Ⅲ Trial for Combination Treatment of PEG-Tα1 and Adefovir for HBeAg-positive Chronic Hepatitis B (PEG-Tα1)

Hepatitis B, Chronic

China
Asian-Pacific Alliance of Liver Disease, Beijing
Beijing Ditan Hospital; National Health and Family Planning Commission, P.R... and other collaborators

Unknown

Emtricitabine for Naive Chinese Chronic Hepatitis B Patients

Hepatitis B, Chronic
Hoffmann-La Roche

Completed

A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With Hepatitis Be Antigen (HBeAg) Positive Chronic Hepatitis B (CHB).

Hepatitis B, Chronic

China, Hong Kong, Australia, Germany, Taiwan, Singapore, France, United States, Korea, Republic of, New Zealand, Thailand, Russian Federation, Brazil
National Taiwan University Hospital
National Science Council, Taiwan

Unknown

Entecavir and Pegasys Sequential Therapy Versus Pegasys for HBeAg Positive Chronic Hepatitis B

Hepatitis B, Chronic

Taiwan
Changhai Hospital

Completed

Optimization of Antiviral Therapy of Chronic HBV Infection

Hepatitis B | Adverse Effects | Australia Antigen Positive

China
Yonsei University
Pusan National University Hospital

Completed

Continuing Lamivudine vs Switching to Entecavir in Patients With Detectable HBV DNA

Hepatitis B, Chronic

Korea, Republic of
Yonsei University
Pusan National University Hospital

Completed

Continuing Lamivudine Versus Switching to Entecavir in Patients Who Achieved Undetectable HBV DNA

Hepatitis B, Chronic

Korea, Republic of
Novartis Pharmaceuticals

Completed

Effects of Telbivudine and Tenofovir Disoproxil Fumarate Treatment on the Hepatitis B Virus DNA Kinetics in CHB

Hepatitis B Virus

China

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