Clinical Trials on DNA

Total 23023 results

Hanyang University
Roche Pharma AG

Unknown

Efficacy Study of Sequential Therapy of Peginterferon Alfa-2a Following Entecavir in Patient With Chronic Hepatitis B. (POTENT)

Hepatitis B, Chronic

Korea, Republic of
Pharmasset

Terminated

Efficacy and Safety of Clevudine Compared With Adefovir in Patients With Chronic Hepatitis Due to Hepatitis B Virus (QUASH2)

Hepatitis B | Chronic Hepatitis

United States, Canada, China, Argentina, Taiwan, Spain, Puerto Rico, Australia, Greece, Thailand, United Kingdom
Sun Yat-sen University

Unknown

Early Response to Interferon Combined Short-Term Nucleoside Analogue Therapy in HBeAg(+) Chronic Hepatitis B

Hepatitis B, Chronic

China
Stealth BioTherapeutics Inc.

Active, not recruiting

Study to Evaluate Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease From Nuclear DNA Mutations (nPMD) (NuPower)

Mitochondrial Diseases | Mitochondrial Myopathies | Mitochondrial Complex I Deficiency | Mitochondrial Pathology | Mitochondrial DNA Depletion | Mitochondrial DNA Mutation | Mitochondrial DNA Deletion | Mitochondrial Metabolism Defect

Spain, United States, Italy, Netherlands, Australia, Germany, Hungary, New Zealand, Norway, United Kingdom
bioLytical Laboratories
St Vincent's Hospital Melbourne

Not yet recruiting

A Study to Evaluate Diagnostic Sensitivity and Specificity of iStatis HBsAg Test at the Point-Of-Care Sites

Hepatitis B | Hepatitis B Infection

Australia
bioLytical Laboratories

Recruiting

Diagnostic Sensitivity and Specificity of iStatis HBsAg Test at the Point-Of-Care Site Settings

Hepatitis B | Hepatitis B Infection

South Africa
Centre Hospitalier de Cayenne
University Hospital, Montpellier; Direction Générale de l'Offre de Soins; Hospital...

Recruiting

Molecular Epidemiology of Hepatitis B in Cayenne General Hospital, French Guiana

Hepatitis B, Chronic | Adults

French Guiana
Third Affiliated Hospital, Sun Yat-Sen University

Recruiting

The Clinical Cure Project of Chronic Hepatitis B in China

Hepatitis B, Chronic

China
Centre Hospitalier Universitaire de la Réunion

Not yet recruiting

Epidemiology of Hepatitis B, C and Delta in Reunion Island (HEPEPID)

Hepatitis B | Hepatitis C | Hepatitis D
Sunshine Lake Pharma Co., Ltd.

Completed

Evaluation Freethiadine Tolerance in Healthy Subjects and Patients With Chronic Hepatitis B, Pharmacokinetics Characteristics and Antiviral Activity of Ⅰ Phase of Study

Hepatitis B, Chronic

China
University of Maryland, Baltimore
Baltimore Veterans Affairs Medical Center

Completed

Heplisav-B Revaccination for Hepatitis B Vaccine Nonresponders (HBR2)

HIV Infections | Hepatitis B | Vaccine Response Impaired

United States
Enyo Pharma

Completed

A Study of the Oral Farnesoid X Receptor Modulator EYP001a to Assess Its Safety and Anti-viral Effect in Chronic Hepatitis B Patients in Combination With Pegylated Interferon alpha2a Alone and With Entecavir

Hepatitis B, Chronic

Hong Kong, Korea, Republic of, Taiwan
Daewoong Pharmaceutical Co. LTD.
C&R Research, Inc.

Completed

Evaluate the Efficacy and Safety to Tenofovir Disoproxil in Chronic Hepatitis B Patients (HBV)

Hepatitis B, Chronic

Korea, Republic of
National Institute of Allergy and Infectious Diseases...

Completed

A Comparison of Adefovir and Tenofovir for the Treatment of Lamivudine-Resistant Hepatitis B Virus in People With HIV

HIV Infections | Hepatitis B

United States
F-star Therapeutics, Inc.
CSI Medical Research Pte Ltd

Terminated

Evaluating the Effects of Inarigivir on Immune Response and Viral Markers in Chronic Hepatitis B Patients

Hepatitis B | Hepatitis B, Chronic | HBV

Singapore
The University of Hong Kong

Completed

Risk of Hepatitis B Reactivation in Patients With Prior HBV Exposure Undergoing Rituximab-containing Chemotherapy: A Prospective Study

Exposure to Hepatitis B Virus

Hong Kong
Replicor Inc.

Completed

Combination Treatment With REP 2139-Ca and Pegasys in Patients With Chronic Hepatitis B

Hepatitis B, Chronic
Hologic, Inc.

Completed

Collection of Samples for the Clinical Evaluation of the Aptima HBV (Hepatitis B Virus) Quant (Quantification) Assay (HBVQuant)

Hepatitis B, Chronic

United States, Canada, Germany, Hungary, Turkey, Australia, Bulgaria, Italy, New Zealand, Romania
GlaxoSmithKline

Completed

An Open Label, Multi Centre Phase IV Study of Adefovir Dipivoxil in Korean Patients With Chronic Hepatitis B (CHB)

Hepatitis B, Chronic
Hoffmann-La Roche

Completed

A Study of Treatment With RO6864018 in Virologically Suppressed Participants With Chronic Hepatitis B Virus (HBV) Infection

Hepatitis B, Chronic

Korea, Republic of, Taiwan, Hong Kong, Malaysia, Singapore, New Zealand
Tongji Hospital
Fujian Cosunter Pharmaceutical Co. Ltd; Beijing Kawin Technology Share-Holding...

Completed

Combination Therapy With Interferon Plus Interleukin 2 and Hepatitis B Vaccine in Chronic Hepatitis B Patients

Hepatitis B, Chronic

China
Johann Wolfgang Goethe University Hospital

Unknown

Hepatitis B Patients Under Oral Nucleos(t)Ide Treatment With Intermittent Assessment of Kidney Function (BONIKA)

Hepatitis B, Chronic

Germany
Third Affiliated Hospital, Sun Yat-Sen University
Guangdong Provincial People's Hospital; Guangzhou 8th People's Hospital

Completed

A Two-year Study of Telbivudine in HBeAg Negative Hepatitis (STEN)

Hepatitis B, Chronic

China
Hoffmann-La Roche

Completed

An Observational Study of Pegasys (Peginterferon Alfa-2a) in Chinese Patients With HBeAg Negative Chronic Hepatitis B

Hepatitis B, Chronic

China
Hoffmann-La Roche

Terminated

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7020322 Following Oral Administration in Healthy Participants and Chronic Hepatitis B Patients

Hepatitis B, Chronic

Hong Kong, Taiwan, New Zealand
Hoffmann-La Roche

Completed

A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With Chronic Hepatitis B.

Hepatitis B, Chronic

Russian Federation
Hoffmann-La Roche

Completed

SOFIA-LTT Study: A Study of Intermittent Long Term Treatment With PEGASYS (Peginterferon Alfa-2a (40KD)) in Patients With HBeAg Negative Chronic Hepatitis B (CHB).

Hepatitis B, Chronic

Bulgaria
Hoffmann-La Roche

Completed

A Study to Collect Blood Biomarker Samples From Participants With Chronic Hepatitis B (CHB) Who Received Treatment With Pegasys (Peginterferon Alfa-2a) ± Nucleoside/Nucleotide Analogue

Hepatitis B, Chronic

Thailand, China, Italy, United Kingdom, Korea, Republic of, Taiwan, Austria, Bulgaria, Germany, New Zealand, France, Poland, Portugal, Romania, Greece
Novartis Pharmaceuticals

Completed

Prospective Exploratory Study to Describe Hepatitis B Virus (HBV) Kinetics During Treatment With Telbivudine (EBEREST)

Hepatitis B, Chronic

Spain
Hoffmann-La Roche

Completed

A Study of Pegasys (Peginterferon Alfa-2a) Added to Nucleos(t)Ide Analogue Treatment in Participants With HBeAg-Negative Chronic Hepatitis B Genotype D Showing Stable Hepatitis B Virus (HBV) Deoxyribonucleic Acid (DNA) Suppression

Hepatitis B, Chronic

Italy
Hoffmann-La Roche

Completed

A Study of Peginterferon Alfa-2a in Participants With Chronic Hepatitis B Virus (HBV) in an Expanded Access Program

Hepatitis B, Chronic

New Zealand
Hoffmann-La Roche

Terminated

Effect of RO6871765 and RO7011785 on Immune Response With the Stimulation of Peripheral Blood Mononuclear Cells (PBMCs) in Chinese Healthy Volunteers and Chronic Hepatitis B Patients

Hepatitis B, Chronic

China
Hoffmann-La Roche

Completed

A Follow-Up Study of Patients With HBeAg Positive Chronic Hepatitis B Treated With Pegasys (Peginterferon Alfa-2a) in Study ML22265

Hepatitis B, Chronic

China
Hoffmann-La Roche
Major Science and Technology Special Project of China Eleventh Five-year

Completed

A Study of Peginterferon Alfa-2a [PEGASYS] in Patients With Chronic Hepatitis B Who Are HBeAg Positive

Hepatitis B, Chronic

China
Hoffmann-La Roche

Completed

Analysis of HBV-Specific Immune Response in Patients With HBeAg Negative Chronic Hepatitis B Treated With Pegasys (Peginterferon Alfa-2a (40KD)) - Immunology Sub-Study of ML18253

Hepatitis B, Chronic

Italy
Hoffmann-La Roche

Completed

A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) Plus Entecavir in Treatment-Naive Patients With HBeAg-Positive Chronic Hepatitis B.

Hepatitis B, Chronic

Hong Kong, China
Hoffmann-La Roche

Completed

An Observational Study of Pegasys (Peginterferon Alfa-2a) in Patients With HbeAg-negative Chronic Hepatitis B (Perseas)

Hepatitis B, Chronic

Greece
Hoffmann-La Roche

Completed

A Study of Peginterferon Alfa-2a (40KD) (PEGASYS®) in Participants With Hepatitis B Envelope Antigen (HBeAg) - Positive Chronic Hepatitis B

Hepatitis B, Chronic

Estonia, Lithuania, Latvia
Tongji Hospital
Xiamen Amoytop Biotech Co., Ltd.

Unknown

A Prospective Clinical Trial in Chronic Hepatitis B Patients NAs (Nucleotides or Nucleosides) Experienced (Anchor Study)

Hepatitis B, Chronic

China
First Affiliated Hospital Xi'an Jiaotong University

Unknown

Optimal Time for Tenofovir Treatment of Anti-Hepatitis B Virus (HBV) During the Pregnancy

Hepatitis B, Chronic

China
Hoffmann-La Roche

Completed

A Study of Combination or Sequential Treatment With PEGASYS (Peginterferon Alfa-2a) and Entecavir in Patients With HBeAg Positive Chronic Hepatitis B

Hepatitis B, Chronic

China
Hoffmann-La Roche

Completed

A Study of Early Immunologic Response in Asian Patients With Chronic Hepatitis B, Treated With Pegasys (Peginterferon Alfa-2a (40KD)), Nucleoside Analogues, or Both

Hepatitis B, Chronic

Taiwan, United States, New Zealand, Singapore
Hoffmann-La Roche

Completed

A Study to Evaluate Efficacy and Safety of Peginterferon Alfa-2a (Pegasys) and Adeforvir Dipivoxil (ADV) in Participants With Lamivudine-Resistant Hepatitis B e Antigen (HBeAg)-Positive Chronic Hepatitis B

Hepatitis B, Chronic

China, Hong Kong
Biotest Pharmaceuticals Corporation

Withdrawn

Nabi-HB Administered Subcutaneously in Patients With Hepatitis B Virus Post Liver Transplantation (Nabi-HB-SC)

Hepatitis B, Chronic
Jiangsu Hansoh Pharmaceutical Co., Ltd.
Nanjing Medical University

Completed

Phase II Trial for Combination Treatment of PEG-Tα1 and Adefovir for HBeAg Positive Chronic Hepatitis B (PEG-Tα1)

Hepatitis B, Chronic

China
Asian-Pacific Alliance of Liver Disease, Beijing
Beijing Ditan Hospital; National Health and Family Planning Commission, P.R... and other collaborators

Unknown

Emtricitabine for Naive Chinese Pregnant Chronic Hepatitis B Patients

Hepatitis B, Chronic | Pregnancy
Ying-Jie Ji

Completed

Efficacy and Safety Study of Adefovir and Entecavir for Elderly With Chronic Hepatitis B

Hepatitis B, Chronic

China
Hoffmann-La Roche

Completed

A Study of Pegasys Monotherapy in Patients With Chronic Hepatitis B Who Have Participated in Previous Studies

Hepatitis B, Chronic

Taiwan, United States, New Zealand, Singapore
Bristol-Myers Squibb

Completed

Entecavir Plus Adefovir Combination Therapy Versus Entecavir Monotherapy vs Therapy With Adefovir Plus Lamivudine for Chronic Hepatitis B Infected Subjects With Lamivudine-resistant Virus (DEFINE)

Hepatitis B, Chronic

Australia, Korea, Republic of, Taiwan, Thailand, Hong Kong, United States, Poland, Greece, Canada, Singapore, Philippines, Brazil, India, Indonesia, Italy, Malaysia, Russian Federation, Turkey
Genexine, Inc.

Completed

Tolerability, Immunogenicity and Efficacy of HB-110 Administered by Electroporation in Chronic Hepatitis B Patients

Hepatitis B, Chronic

Korea, Republic of

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