Clinical Trials on DOCK8 Deficiency in Spain

Total 459 results

Abivax S.A.

Completed

A Safety, Pharmacokinetics, and Pharmacodynamics Study of ABX464 in HIV-1 Seronegative and Seropositive Adults

HIV Infections | Health Volunteers

Spain
Parc de Salut Mar
Universitat Pompeu Fabra

Completed

Zinc Supplementation Impact in Acute COVID-19 Clinical Outcomes (MARZINC)

Zinc Deficiency | Sars-CoV-2 Infection

Spain
Judit Pich Martínez

Completed

Safety and Immunogenicity of a Vaccine Dendritic Cell-based Pulsed With Autologous Heat-inactivated in HIV-1 Infected Patients

HIV Infection

Spain
Juan A. Arnaiz

Completed

Study to Evaluate the Activity and Tolerability of Lopinavir/Ritonavir and Lamivudine Bitherapy in HIV Patients With Viral Suppression (OLE)

HIV Infection

Spain
Pharvaris Netherlands B.V.

Recruiting

Extension Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema (RAPIDe-2)

Hereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | Hereditary Angioedema Types I and II | Hereditary Angioedema Attack | Hereditary Angioedema With C1 Esterase Inhibitor Deficiency | Hereditary Angioedema - Type 1 | Hereditary Angioedema - Type 2 | C1 Esterase Inhibitor... and other conditions

United States, Bulgaria, Czechia, Hungary, Spain, France, Germany, Poland, Canada, Israel
Anna Cruceta

Recruiting

Bictegravir/FTC/TAF for the Treatment of Primary HIV Infection (BIC-PHI)

HIV Primary Infection

Spain
Hospitales Universitarios Virgen del Rocío

Active, not recruiting

Humoral and Cellular Immunity Against SARS-COV-2 Vaccine in HIV-infected Patients Immunosuppressed

HIV Infection | SARS-CoV-2 RNA Vaccines

Spain
Germans Trias i Pujol Hospital
Fundación FLS de Lucha Contra el Sida, las Enfermedades Infecciosas y la... and other collaborators

Completed

Study to Evaluate the Influence of Nevirapine to Atazanavir in Steady State Equilibrium in HIV Patients

HIV Infections

Spain
IrsiCaixa

Completed

Treatment With Immunological Checkpoint Inhibitors of HIV-infected Subjects With Cancer (PembroHIV)

HIV Infection | Cancer

Spain
Instituto de Investigación Hospital Universitario...
Universidad Autonoma de Madrid; Fundación para el Fomento de la Investigación... and other collaborators

Completed

Safety Infusion of NatuRal KillEr celLs or MEmory T Cells as Adoptive Therapy in COVID-19 pnEumonia or Lymphopenia (RELEASE)

Corona Virus Infection

Spain
David Garcia Cinca
Fundacion Clinic per a la Recerca Biomédica

Unknown

Simplification Study of HIV-1 Infected Patients With Virological Suppression Under the Combination of Lamivudine (150 mg BID) Plus Raltegravir (400 mg BID) Switching to Lamivudine (300 mg QD) Plus Raltegravir (1200 mg QD) : Roll-over Study of the RALAM (RALAM-RollOver)

HIV Infections | HIV Seropositivity | HIV-1-infection

Spain
David Garcia Cinca
Fundacion Clinic per a la Recerca Biomédica

Unknown

Study With Dual Therapy Including Lamivudine (300 mg QD) Plus Raltegravir (1200 mg QD) in Virologically Suppressed HIV-1 Infected Patients Experiencing Inconvenience, Toxicity, Negative Impact on Co-morbidities or Risk of Drug-drug Interactions With Their Current Regimen (RALAM-II)

HIV Infections | HIV Seropositivity | HIV-1-infection

Spain
Asociacion para el Estudio de las Enfermedades...
Merck Sharp & Dohme LLC

Completed

Bitherapy With the Combination of Raltegravir and Darunavir (BIRDi) (BIRDi)

HIV/AIDS | Comorbidities

Spain
Eva Bonfill

Recruiting

Safety, Tolerance and Antiretroviral Activity of Dasatinib: a Pilot Clinical Trial in Patients With Recent HIV-1 Infection (DASAHIVCURE)

Recent HIV-1 Infection

Spain
AMAG Pharmaceuticals, Inc.

Completed

A Trial Comparing Ferumoxytol With Iron Sucrose for the Treatment of Iron Deficiency Anemia

Iron Deficiency Anemia

Germany, Poland, United Kingdom, Australia, France, Hungary, Italy, Korea, Republic of, Latvia, Lithuania, Romania, South Africa, Spain, Ukraine
Francisco Javier Martínez Noguera

Completed

Effect of 8-week Intake of 2S-hesperidin on Performance, Body Composition and Biochemicals Markers in Amateur Cyclists (HESPERFORMAN)

Inflammatory Response | Oxygen Deficiency | Oxidative Stress | Acid-Base Imbalance | Metabolic Disturbance | Muscle Loss | Power | Electrolyte Disturbance | Change, Body Weight | Changes Fatty

Spain
Hospital Clinic of Barcelona

Completed

Safety and Immunological Response of a Boosting Dose of MVA-B in Healthy Volunteers After 4 Years of Receiving MVA-B

HIV Infections

Spain
UCB BIOSCIENCES, Inc.
Zogenix, Inc.

Active, not recruiting

An Open-Label Study of Continuation Treatment With Combination Pyrimidine Nucleosides in Patients With TK2 Deficiency (Continuation)

Thymidine Kinase 2 Deficiency

United States, Israel, Spain
IrsiCaixa
José Moltó Marhuenda, PhD, MD; Beatriz Mothe Pujadas PhD,MD; Susana Benet Garrabé... and other collaborators

Completed

A Phase I, Randomized, Double-Blind, Placebo-Controlled Safety, Tolerability and Immunogenicity Study of Candidate HIV-1 Vaccines ChAdOx1.HTI and MVA.HTI With Recombinant HIV-1 Envelope Protein ConM SOSIP.v7 gp140 Vaccine, Adjuvanted With MPLA Liposomes in ART-Suppressed HIV-1 Positive Individuals

HIV Infection

Spain
Hospital Clinic of Barcelona

Completed

A Study to Evaluate the Safety of the HIV-1 Vaccine MVA-B in Chronic HIV-1 Infected Patients Successfully Treated With HAART (2009-016578-34)

HIV Infection

Spain
Ines Perez

Terminated

Analysis of Changes in Adipose Tissue of Patients With Lipoatrophy HIV Infection Treated With Nucleoside Thymidine, After Switching to Monotherapy With Lopinavir / Ritonavir (BIOKAL)

HIV Infections

Spain
Hospitales Universitarios Virgen del Rocío

Completed

Plasma and Intracellular Concentrations of Raltegravir and Etravirine Administered Once Daily (RAET)

HIV Infections | HIV-1 Infection

Spain
Fundación Pública Andaluza para la Investigación...
Merck Sharp & Dohme LLC

Unknown

Neuropsyquiatric Evolution After Introduction of Raltegravir QD in Substitution of Dolutegravir: NEAR QD Study (NEARQD)

HIV Infections

Spain
Juan A. Arnaiz
Germans Trias i Pujol Hospital; Fundació Institut de Recerca de l'Hospital... and other collaborators

Unknown

Effects of 2 Initial Standard Antiretroviral Combinations Therapies on Lipid Metabolism (LIPOTAR-07)

HIV Infections

Spain
Origin Biosciences

Completed

Study of ORGN001 (Formerly ALXN1101) in Neonates, Infants and Children With Molybdenum Cofactor Deficiency (MOCD) Type A

Molybdenum Cofactor Deficiency, Type A

United States, Spain, Israel, Norway, Turkey, United Kingdom
University of Alicante

Completed

Prevention of Energy Deficit Syndrome in Female Athletes. Molecular Mechanisms Associated With Malnutrition.

Sports Physical Therapy | Antioxidative Stress | Nutritional Disorder | Female Athlete Triad | Mediterranean Diet | Energy Deficit Syndrome | Red Fruits

Spain
Octapharma

Recruiting

Efficacy of Atenativ in Patients With Congenital Antithrombin Deficiency Undergoing Surgery or Delivery

Congenital Antithrombin Deficiency

Spain, Italy, United States, Serbia, France, Hungary, Austria, Germany, United Kingdom, Israel
Hospital Clinic of Barcelona

Completed

Atazanavir or Lopinavir in HIV Post-exposure Prophylaxis

HIV Infections

Spain
Hospital Clinic of Barcelona

Terminated

Immune Reconstitution in naïve HIV Patients With CD4 <100 Cells/mL When Treated With Lopinavir or Efavirenz.

HIV Infection

Spain
Instituto de Investigación Sanitaria de la Fundación...

Completed

The Benefits of Immediate Treatment Initiation Without Immunovirological Data Compared to Conventional BIC / FTC / TAF Treatment in Naive Patients With Type 1 HIV (Human Immunodeficiency Virus) Infection

HIV-1-infection

Spain
David Garcia Cinca
Fundacion Clinic per a la Recerca Biomédica

Unknown

Simplification From Tenofovir Plus Lamivudine or Emtricitabine Plus Ritonavir-Boosted-Protease Inhibitor to Ritonavir-Boosted-Atazanavir Plus Lamivudine in Virologically-Suppressed-HIVInfected Adults With Osteopenia (Osteosimply014)

Human Immunodeficiency Virus

Spain
Hospital Clinic of Barcelona
Fundacion Clinic per a la Recerca Biomédica

Completed

High Definition White-Light Colonoscopy vs. Chromoendoscopy for Surveillance of Lynch Syndrome. (EndoLynch)

Lynch Syndrome

Spain
Fundacion para la Investigacion Biomedica del Hospital...

Completed

Bryostatin-1 Effect on HIV-1 Latency and Reservoir in HIV-1 Infected Patients Receiving Antiretroviral Treatment (BRYOLAT)

HIV Infection

Spain
Juan A. Arnaiz

Completed

A Phase I Study of Modified Vaccinia Virus Ankara (MVA-B) in Healthy Volunteers at Low Risk of HIV Infection (RisVac02)

HIV Infections

Spain
Agios Pharmaceuticals, Inc.

Terminated

Pyruvate Kinase (PK) Deficiency Global Longitudinal Registry: Patient-Reported Outcomes (PRO) (PKD)

Anemia | Anemia, Hemolytic | Pyruvate Kinase Deficiency | Pyruvate Kinase Deficiency Anemia

United States, United Kingdom, Italy, Spain, Netherlands
Fundacion SEIMC-GESIDA
Janssen-Cilag, S.A.

Completed

A Clinical Trial to Evaluate the Reversibility of Abacavir/Lamivudine/Dolutegravir CNS-Related Neurotoxicity After Switching to Tenofovir/Alafenamide/Emtricitabine/Darunavir/Cobicistat (TAF/FTC/DRV/c) (DETOX)

HIV Infections

Spain
Faes Farma, S.A.

Completed

Efficacy and Safety of Calcifediol vs Placebo in Subjects With Vitamin D Deficiency (WORFEROL)

Vitamin D Deficiency | Vitamin D Insufficiency

Spain, France, Bulgaria, Czechia, Italy, Serbia, Slovakia
Fundacion SEIMC-GESIDA

Completed

A Phase IV, Open-label, Randomised, Pilot Clinical Trial Designed to Evaluate the Potential Neurotoxicity of Dolutegravir/Lamivudine/Abacavir in Neurosymptomatic HIV Patients and Its Reversibility After Switching to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide. DREAM Study (DREAM)

HIV Infections

Spain
Germans Trias i Pujol Hospital

Completed

Efficacy And Security Of Annual And Biennial Zoledronic Acid For Osteoporosis Treatment In An HIV-Infected Patients' Cohort

HIV Infections

Spain
Applied Biology, Inc.
Hospital Universitario Ramon y Cajal

Withdrawn

In-vitro Diagnostic Test to Predict COVID-19 Mortality and Disease Severity

COVID-19 | SARS-CoV 2 | COVID | Androgenetic Alopecia | Androgen Deficiency | Androgen Receptor Abnormal

Spain
AB Biotek

Completed

Efficacy and Tolerability of ABBC1 in Volunteers Receiving the Influenza or Covid-19 Vaccine

Immunologic Deficiency Syndromes | Covid19 | Vaccine Reaction | Influenza | Immunity | Cytokine Storm

Spain
Hospital Clinic of Barcelona

Completed

Strategies of Interruption/Reinitiation of Antiretroviral Therapy in HIV-Infected Patients With Lipodystrophy

HIV-Associated Lipodystrophy Syndrome

Spain
Fundacion IMIM

Completed

ADHEPTA Study: Adherence Questionnaire in Hepatitis C (ADHEPTA)

HIV Infection | Hepatitis C, Chronic

Spain
Hospital Costa del Sol

Recruiting

Effectiveness of a Multifactorial Intervention in Frailty Individuals With HIV Infection: HIDRA360 (HIDRA360)

HIV Infections | Frailty Syndrome

Spain
Casen Recordati S.L.

Completed

Cross-sectional, Non-randomized Observational Study to Assess the Frequency of Reduced Sodium Intake in the Primary Care Setting - LAXAP (LAXAP)

Dietary Deficiency | Sodium

Spain
Hospitales Universitarios Virgen del Rocío
Bristol-Myers Squibb

Completed

Pharmacokinetic Interactions Between Telaprevir and Un-boosted Atazanavir

HIV Infection | Hepatitis C, Chronic

Spain
Ultragenyx Pharmaceutical Inc

Active, not recruiting

Long Term Follow Up to Evaluate DTX301 in Adults With Late-Onset OTC Deficiency (CAPtivate)

Ornithine Transcarbamylase (OTC) Deficiency

Canada, United States, France, Spain, United Kingdom
Hospital Clinic of Barcelona
European Society of Gastrointestinal Endoscopy

Recruiting

Evaluation of ArTificial Intelligence System (Gi-Genius) for adenoMa dEtection in Lynch Syndrome. (Timely)

Lynch Syndrome

Spain
Hospital Universitari Son Dureta
Fondo de Investigacion Sanitaria; Hospital Son Llatzer

Unknown

Conjugate And Polysaccharide Vaccines Compared With Polysaccharide Vaccine In Hiv-Infected Adults

HIV Infections | HIV | Pneumococcal Vaccines

Spain
University of Modena and Reggio Emilia

Completed

Aging With HIV at Younger vs Older Age: a Diverse Population With Distinct Comorbidity Profiles (Aging_in_HIV)

HIV Infection | Aging

Australia, Italy, Spain

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