Clinical Trials on Degeneration; Bone in Netherlands

Total 798 results

Ipsen

Completed

Efficacy and Safety Study of Varying Doses of Lanreotide Autogel in Patients With Acromegaly

Acromegaly

United States, Germany, Hong Kong, Czechia, France, Hungary, Netherlands, United Kingdom
Nationwide Children's Hospital
Children's Hospital Colorado

Recruiting

MEKTOVI® for the Treatment of Pediatric Adamantinomatous Craniopharyngioma

Adamantinous Craniopharyngioma | Recurrent Adamantinomatous Craniopharyngioma

United States, United Kingdom, Australia, Canada, Germany, Netherlands
International AIDS Vaccine Initiative
GlaxoSmithKline; George Washington University; Amsterdam UMC, location VUmc; Rockefeller...

Active, not recruiting

A Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant HIV-1 Envelope Protein BG505 SOSIP.GT1.1 gp140 Vaccine, Adjuvanted in Healthy, HIV-uninfected Adults

HIV Infections

United States, Netherlands
European Organisation for Research and Treatment...
Medical Research Council

Completed

Combination Chemotherapy and Surgery With or Without G-CSF in Treating Patients With Osteosarcoma

Sarcoma

France, Saudi Arabia, Denmark, Belgium, Netherlands, Portugal, Slovenia, United Kingdom
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Etanercept for the Treatment of Refractory Heel Enthesitis in Spondylarthropathy

Spondylarthropathies, Enthesitis

France, Germany, Netherlands
Hoffmann-La Roche

Completed

A Study of RO5428029 in Healthy Volunteers and Patients With Chronic Hepatitis C

Hepatitis C, Chronic, Healthy Volunteer

Poland, France, Netherlands
Ipsen

Completed

Validation Study of the SAGIT® Instrument in Acromegaly (SAGIT)

Acromegaly

United States, United Kingdom, Italy, Netherlands, France, Belgium, Brazil, Denmark, Germany, Spain
Santhera Pharmaceuticals

Completed

A Study of Efficacy, Safety and Tolerability of Idebenone in the Treatment of Friedreich's Ataxia (FRDA) Patients (MICONOS)

Friedreich's Ataxia

Netherlands, Austria, United Kingdom, Belgium, France, Germany
Centocor, Inc.
Schering-Plough

Completed

A Study of the Safety and Efficacy of Golimumab in Subjects With Active Ankylosing Spondylitis

Spondylitis, Ankylosing

United States, Germany, Finland, Taiwan, Korea, Republic of, Canada, Belgium, Netherlands, France
Incyte Corporation
Novartis

Completed

Study of the JAK Inhibitor Ruxolitinib Administered Orally to Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera-Myelofibrosis (PPV-MF) or Post-Essential Thrombocythemia-Myelofibrosis (PET-MF)

Myelofibrosis

France, United Kingdom, China, United States, Netherlands, Germany, Italy, Austria
Ipsen

Completed

Study to Determine the Maximum Tolerated Dose, Safety and Tolerability of a Single Dose of Lanreotide Prolonged Release Formulation (PRF) in Subjects With Acromegaly

Acromegaly

France, Germany, Spain, Belgium, Russian Federation, United Kingdom, Italy, Lithuania, Czechia, Romania, Poland, Netherlands
Ataxia Study Group

Recruiting

The EUROSCA Natural History Study (EUROSCA-NHS)

Spinocerebellar Ataxia

Austria, Belgium, France, Germany, Hungary, Italy, Netherlands, Poland, Spain, United Kingdom
Alector Inc.

Active, not recruiting

A Phase 2 Study to Evaluate Safety of Long-term AL001 Dosing in Frontotemporal Dementia (FTD) Patients (INFRONT-2)

Frontotemporal Dementia

Canada, United States, Germany, United Kingdom, Italy, Netherlands
Ipsen

Completed

Study to Assess the Efficacy of an Extended Injection Interval Schedule of Lanreotide Autogel in Acromegalic Subjects (LEAD)

Acromegaly

France, Brazil, Denmark, Finland, Greece, Korea, Republic of, Latvia, Netherlands, Norway, Poland, Romania, Russian Federation, Serbia, Sweden
Amgen

Completed

A Study of Apremilast Use and Effectiveness in Patients With Psoriatic Arthritis in The Netherlands (REWARD)

Arthritis, Psoriatic

Netherlands
Pfizer

Completed

Study Comparing Etanercept (ETN) Against a Placebo for Etanercept on a Background Nonsteroidal Anti Inflammatory Drug (NSAIDs) in the Treatment of Early Spondyloarthritis (SpA) Patients Who do Not Have X-ray Structural Changes (EMBARK)

Spondylitis, Ankylosing

Belgium, Korea, Republic of, Spain, France, Taiwan, Germany, Argentina, Czech Republic, United Kingdom, Hungary, Russian Federation, Colombia, Finland, Netherlands
Ultragenyx Pharmaceutical Inc

Active, not recruiting

Setrusumab vs Bisphosphonates in Pediatric Subjects With Osteogenesis Imperfecta (Cosmic)

Osteogenesis Imperfecta

United States, Italy, Brazil, France, Canada, Germany, Netherlands, Poland
Novartis Pharmaceuticals

Completed

Zoledronic Acid in the Prevention of Cancer Treatment Related Bone Loss in Postmenopausal Women Receiving Letrozole for Breast Cancer.

Breast Cancer | Bone Loss

Egypt, Taiwan, Hong Kong, Thailand, Argentina, Germany, United Kingdom, Colombia, Belgium, Spain, Philippines, Italy, Brazil, China, Finland, Chile, Guatemala, Netherlands, New Zealand, Switzerland, Portugal, Venezuela, Australia, Czech... and more
Novartis Pharmaceuticals

Completed

Study of Pasireotide Long Acting Release (LAR) Injection in Patients With Acromegaly and Patients With Carcinoid Disease

Acromegaly | Carcinoid Tumor

Germany, Belgium, Canada, Netherlands, United States, Norway
Adhera Health, Inc.
Maastricht University Medical Center; Hospital Universitario Reina Sofia de... and other collaborators

Completed

CARINAE for Stress Relief in Perioperative Care (CARINAE)

Kidney Cancer | Scoliosis | Prostate Cancer | Bladder Cancer | Knee Replacement | Orthognathic Surgery | Coronary Artery Bypass Surgery | Hip Replacement | Psychological Stress | Cardiopulmonary Bypass Surgery | Cardiac Valve Replacement

Netherlands, Spain, Italy
European Organisation for Research and Treatment...

Completed

Infliximab in Treating Patients With Myelodysplastic Syndrome

Myelodysplastic Syndromes

France, Belgium, Netherlands, Czech Republic, Italy, Germany
Vericel Corporation

Completed

Superiority of MACI® Versus Microfracture Treatment in Patients With Symptomatic Articular Cartilage Defects in the Knee (SUMMIT)

Articular Cartilage Defect

Netherlands, Norway, France, Czechia, Sweden, Poland, United Kingdom
GlaxoSmithKline

Terminated

A Phase IIa Study Of Men And Post-Menopausal Women With A Fractured Distal Radius

Fracture Healing

Russian Federation, Argentina, Hong Kong, Netherlands, Spain, Taiwan, Korea, Republic of, Australia, United Kingdom, Czech Republic, South Africa, Romania, Sweden
Alfasigma S.p.A.

Terminated

Eurartesim® in Patients With Imported Uncomplicated Plasmodium Vivax Malaria

Malaria, Vivax

Switzerland, France, Germany, Israel, Italy, Netherlands, Spain
AbbVie

Completed

Real World Evidence of the Effectiveness of Paritaprevir/r - Ombitasvir, ± Dasabuvir, ± Ribavirin and Patient Support Program in Patients With Chronic Hepatitis C (3DUTCH)

Chronic Hepatitis C

Netherlands
Novartis Pharmaceuticals

Completed

Extension in AS: Sustainability of Benefits, Safety and Tolerability (MEASURE 1 ext)

Spondylitis, Ankylosing

Belgium, Germany, Netherlands, France, United States, Bulgaria, Italy, Mexico, Russian Federation, Peru, United Kingdom, Turkey, Canada, Taiwan
Eli Lilly and Company

Completed

A Study of Ixekizumab (LY2439821) in TNF Inhibitor Experienced Participants With Radiographic Axial Spondyloarthritis (COAST-W)

Spondyloarthritis

Italy, Japan, United States, Puerto Rico, Spain, Mexico, Netherlands, France, Poland, Israel, Argentina, Brazil, Canada, Korea, Republic of, Germany, Finland, United Kingdom
Novartis Pharmaceuticals

Completed

A Phase Ib/II Dose-finding Study to Assess the Safety and Efficacy of LDE225 + INC424 in Patients With MF

Bone Marrow Diseases | Hematologic Diseases | Blood Coagulation Disorders | Hemorrhagic Disorders | Primary Myelofibrosis | Myeloproliferative Disorders | Polycythemia Vera | Thrombocytosis | Essential Thrombocythemia | Blood Platelet Disorders

United Kingdom, Belgium, Canada, France, Australia, Netherlands, Spain, Denmark, Ireland, Italy, Germany
Novartis Pharmaceuticals

Completed

Controlled Myelofibrosis Study With Oral Janus-associated Kinase (JAK) Inhibitor Treatment-II: The COMFORT-II Trial

Myelofibrosis

France, United Kingdom, Belgium, Germany, Netherlands, Italy, Austria, Spain, Sweden
NightstaRx Ltd, a Biogen Company

Enrolling by invitation

Long-term Safety and Efficacy Follow-up of BIIB111 for the Treatment of Choroideremia and BIIB112 for the Treatment of X-Linked Retinitis Pigmentosa (SOLSTICE)

Choroideremia | X-Linked Retinitis Pigmentosa

United States, United Kingdom, Netherlands, Germany, France, Brazil, Canada, Denmark, Finland
Alexion

Completed

A Study of Ravulizumab (ALXN1210) in Children and Adolescents With Paroxysmal Nocturnal Hemoglobinuria

Paroxysmal Nocturnal Hemoglobinuria

France, United Kingdom, Norway, Russian Federation, Netherlands, United States
Institut für Pharmakologie und Präventive Medizin
Edwards Lifesciences

Recruiting

The ReTAVI Prospective Observational Registry

Aortic Valve Stenosis | Structural Valve Degeneration | Structural Valve Deterioration

Austria, Spain, Switzerland, France, Italy, Germany, Poland, Canada, Israel, Netherlands, Portugal, United Kingdom
Intrinsic Therapeutics

Active, not recruiting

A Prospective, Randomized, Multicenter Study to Demonstrate the Superiority of the Barricaid to Discectomy for Primary Lumbar Disc Herniation

Lumbar Disc Herniation

Germany, Austria, Netherlands, Belgium, France, Switzerland
Pfizer

Completed

Pegvisomant And Sandostatin LAR Combination Study

Acromegaly

Canada, United States, Germany, Italy, United Kingdom, Norway, Australia, Spain, Brazil, Mexico, France, Netherlands
Clementia Pharmaceuticals Inc.

Terminated

An Efficacy and Safety Study of Palovarotene for the Treatment of MO (MO-Ped)

Exostoses, Multiple Hereditary

United States, Spain, Canada, Japan, Italy, Portugal, United Kingdom, Turkey, Australia, Belgium, France, Netherlands
Public Health Service of Amsterdam
ZonMw: The Netherlands Organisation for Health Research and Development; Amsterdam... and other collaborators

Recruiting

Interventions to Curb Hepatitis C Reinfections Among Men Who Have Sex With Men (ICECREAM)

Hepatitis C Virus Infection

Netherlands, France
Amgen

Terminated

A Phase 1 Study of AMG 330 in Subjects With Myeloid Malignancies

Myelodysplastic Syndrome | Relapsed/Refractory AML | Minimal Residual Disease Positive AML

United States, Canada, Germany, Netherlands
Kyowa Kirin Pharmaceutical Development Ltd

Completed

A Study to Describe the Lived Experience of XLH for Adolescents at End of Skeletal Growth

X-Linked Hypophosphatemia

France, United Kingdom, Spain, Germany, Netherlands
BioMarin Pharmaceutical

Terminated

A Clinical Assessment Study of Subjects With Mucopolysaccharidosis IVA (Morquio Syndrome)

Morquio A Syndrome | MPS IV A | Mucopolysaccharidosis IVA

France, United Kingdom, Taiwan, United States, Argentina, Netherlands, Canada, Brazil, Germany, Italy
Pfizer

Completed

Etanercept Withdrawal And Retreament Study In Subjects With Nr-ax SpA (RE-EMBARK)

Spondylitis, Ankylosing

United States, Sweden, Taiwan, Colombia, Hungary, Belgium, Australia, Finland, Netherlands, Spain, Czechia, Poland, France, Germany
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Etanercept and Sulphasalazine in Ankylosing Spondylitis

Ankylosing Spondylitis

France, Poland, Italy, Germany, Spain, United Kingdom, Denmark, Austria, China, Ireland, Hungary, Finland, Netherlands, Australia, Czech Republic, Qatar, Saudi Arabia, Sweden
Erasmus Medical Center
Leiden University Medical Center; Medical Center Haaglanden; Rijnstate Hospital; Maasstadziekenhu... and other collaborators

Recruiting

HIV Indicator Diseases in Hospital and Primary Care (#AwareHIV)

HIV Infections | Acquired Immunodeficiency Syndrome | Sexually Transmitted Diseases, Viral | Pneumonia | Psoriasis | Weight Loss | Thrombocytopenia | Leukopenia | Dermatitis, Seborrheic | Herpes Zoster | Lymphadenopathy | Uterine Cervical Dysplasia | Primary Health Care | Diarrhea Chronic | Candida Infection | Infectious... and other conditions

Netherlands
Foundation for Liver Research
Hoffmann-La Roche

Completed

PEG-interferon Alfa-2a add-on Study in HBeAg Negative Chronic Hepatitis B Patients (PAS)

Chronic Hepatitis B

Netherlands, Canada
The Netherlands Cancer Institute
Bayer

Completed

Registry of Treatment Outcomes of Symptomatic Metastasized Castration Resistant Prostate Cancer Treated With Radium-223 (ROTOR)

Bone Metastases | Prostate Cancer Metastatic

Netherlands
AO Clinical Investigation and Publishing Documentation
AOCMF

Active, not recruiting

Medication-related Osteonecrosis of the Jaw (MRONJ) Registry (MRONJ)

Bisphosphonate-Associated Osteonecrosis of the Jaw | Medication-related Osteonecrosis of the Jaw

Germany, Qatar, Switzerland, Finland, United States, Slovenia, Spain, Netherlands, Romania, Korea, Republic of
Eli Lilly and Company

Completed

A Study of Ixekizumab (LY2439821) in Participants With Nonradiographic Axial Spondyloarthritis (COAST-X)

Axial Spondyloarthritis

United States, Puerto Rico, Russian Federation, Mexico, Poland, Argentina, Austria, Brazil, Canada, Czechia, Finland, Germany, Japan, Korea, Republic of, Netherlands, Romania
Kyowa Kirin, Inc.
Kyowa Kirin Co., Ltd.

Completed

Study of KRN23 (Burosumab), a Recombinant Fully Human Monoclonal Antibody Against Fibroblast Growth Factor 23 (FGF23), in Pediatric Subjects With X-linked Hypophosphatemia (XLH)

X-linked Hypophosphatemia

Netherlands, United States, United Kingdom, France
Merck Sharp & Dohme LLC

Completed

Golimumab (MK-8259 / SCH900259) Treatment Withdrawal in Participants With Non-radiographic Axial Spondyloarthritis (GO-BACK) (MK-8259-038)

Spondyloarthritis

Czechia, Germany, Netherlands, Poland, Romania, Russian Federation, Spain, Turkey, Ukraine
FORUM Pharmaceuticals Inc

Unknown

Study to Assess the Safety, Tolerability, and Pharmacodynamic (PD) Effects of FRM-0334 in Subjects With Prodromal to Moderate Frontotemporal Dementia With Granulin Mutation

Granulin Mutation

Belgium, United States, France, Italy, Netherlands, United Kingdom
Kiadis Pharma

Completed

Transplant-Related Mortality in Patients Undergoing a Peripheral Blood Stem Cell Transplantation or an Umbilical Cord Blood Transplantation

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

United States, Canada, Netherlands, Germany, Belgium, United Kingdom

Clinical Trials on Degeneration; Bone in Netherlands

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