Clinical Trials on Degenerative Disc Disease(DDD) in Ireland

Total 62 results

SpinalMotion

Terminated

Kineflex|C Artificial Disc System to Treat Cervical Degenerative Disc Disease (DDD)

Degenerative Disc Disease (DDD)

United States
Baxter Healthcare Corporation
Apatech, Inc.

Completed

Performance of Inductigraft in Spinal Fusion (APOLLO)

Spinal Stenosis of Lumbar Region | Degenerative Disk Disease

Ireland, Germany, Spain, United Kingdom, Hungary
Synergy Spine Solutions
MCRA

Recruiting

Real World Data Collection on the Synergy Disc

Cervical Degenerative Disc Disease

Ireland
Spineology, Inc

Completed

Spineology Clinical Outcomes Trial: An IDE Investigation (SCOUT)

Lumbar Degenerative Disc Disease

United States
SpinalMotion

Terminated

Kineflex Artificial Disc System to Treat Degenerative Disc Disease (DDD)

Degenerative Disc Disease

United States
NuVasive

Enrolling by invitation

Advanced Materials Science in XLIF Study (AMS in XLIF)

Degenerative Disc Disease | Spondylolisthesis

United States
Providence Medical Technology, Inc.

Active, not recruiting

Study of Posterior Cervical Stabilization System (PCSS) as Part of Circumferential Fusion to Treat Multilevel DDD (FUSE)

Degenerative Disc Disease

United States
Spinal Restoration, Inc.

Terminated

Treatment of Symptomatic Lumbar Internal Disc Disruption (IDD) With the Biostat® System

Back Pain | Degenerative Disc Disease | Chronic Low Back Pain | Internal Disc Disruption

United States
Mesoblast, Ltd.
Quintiles, Inc.

Completed

Placebo-controlled Study to Evaluate Rexlemestrocel-L Alone or Combined With Hyaluronic Acid in Participants With Chronic Low Back Pain (MSB-DR003)

Degenerative Disc Disease

United States, Australia
VisionCare, Inc.

Terminated

Study of WA-NG (NG-IMT) Telescope Prosthesis in Patients With End-stage Age-related Macular Degeneration

Age Related Macular Degeneration

Ireland, Spain
Seikagaku Corporation

Completed

A Study of SI-6603 in Patients With Lumbar Disc Herniation

Lumbar Disc Disease | Intervertebral Disc Disease

United States
Bayer

Completed

Study to Assess the Effectiveness of Existing Anti vascUlar Endothelial Growth Factor (Anti VEGF) in Patients With Wet Age-related Macular Degeneration (wAMD) (AURA) (AURA)

Ophthalmology, Macular Degeneration

Japan, France, Germany, Australia, Italy, United Kingdom, Venezuela, Ireland, Netherlands, Canada
Novartis

Completed

Safety and Tolerability of an Intravenous Infusion of ACZ885 in Patients With Wet Age-Related Macular Degeneration

Wet Age-Related Macular Degeneration

United Kingdom, Switzerland
VisionCare, Inc.

Recruiting

Post-market Clinical Investigation of the SING IMT System, Model NG SI IMT 3X in Patients With End-stage Age-related Macular Degeneration

Age-Related Macular Degeneration | AMD

Italy, Ireland, Spain, Germany, United Kingdom
Bayer

Completed

Assessment of Proactive Treatments in Patients With Wet Age-related Macular Degeneration (wAMD) Which Have Never Undergone Treatment of This Particular Disease (XTEND)

Wet Age-related Macular Degeneration

Canada, Spain, Sweden, Belgium, Argentina, Italy, Korea, Republic of, United Kingdom, China, Denmark, France, Norway, Colombia, Australia, Ireland, Switzerland, Thailand
Zimmer Biomet

Active, not recruiting

A Multicentre Observational Study to Evaluate Clinical Outcomes of the G7 Acetabular System

Rheumatoid Arthritis | Noninflammatory Degenerative Joint Disease

Netherlands, France, Spain, United States, Germany, Ireland
Seikagaku Corporation

Completed

SI-6603 (Condoliase) Study for Lumbar Disc Herniation (Discovery 6603 Study)

Lumbar Disc Herniation

United States
Novartis Pharmaceuticals

Completed

A Non-interventional Study to Assess the Influence of Automated Optical Coherence Tomography Image Enrichment With Segmentation Information on Disease Activity Assessment in Patients Treated With Licensed Anti- VEGF Injections (RAZORBILL)

Neovascular Age-Related Macular Degeneration

Spain, Italy, Germany, Canada, Ireland
Association for Innovation and Biomedical Research...
European Vision Institute Clinical Research Network

Active, not recruiting

A Collaborative Resource of Heidelberg Multimodal Imaging of Intermediate and Early Atrophic AMD Cases to Study Prediction of Disease Progression (INTERCEPT-AMD)

Atrophy | Age Related Macular Degeneration | Prediction | Intermediate AMD

Portugal, France, Germany, Ireland, Italy, Netherlands, Spain, Switzerland, United Kingdom
Queen's University, Belfast
University of Sussex

Unknown

Visual Performance Measures in a Virtual Reality Environment for Assessing Clinical Trial Outcomes in Those With Severely Reduced Vision

Retinitis Pigmentosa | Low Vision | Albinism | Stargardt Disease 1 | Stargardt Disease 3 | Stargardt Disease 4

United Kingdom
QLT Inc.

Completed

Oral QLT091001 in Retinitis Pigmentosa (RP) Subjects With an Autosomal Dominant Mutation in Retinal Pigment Epithelial 65 Protein (RPE65)

Retinitis Pigmentosa (RP)

Canada, Ireland
Renovis

Unknown

Study of REN-1654 in Patients With Sciatica Pain

Sciatica | Radiculopathy | Herniated Disc

United States
Genaera Corporation

Terminated

A Study of MSI-1256F (Squalamine Lactate) To Treat "Wet" Age-Related Macular Degeneration

Macular Degeneration

United States
Conor Fearon
Queen's University

Recruiting

Unstructured Eye Tracking as a Diagnostic and Prognostic Biomarker in Parkinsonian Disorders

Multiple System Atrophy | Corticobasal Degeneration | Progressive Supranuclear Palsy | Parkinson's Disease and Parkinsonism

Ireland
DePuy International

Active, not recruiting

Survivorship of Attune Primary Total Knee Prosthesis

Noninflammatory Degenerative Joint Disease

United States, Hong Kong, Malaysia, United Kingdom, Australia, Austria, Belgium, Canada, Germany, New Zealand, Singapore, Switzerland, Korea, Republic of
Jaeb Center for Health Research
Juvenile Diabetes Research Foundation; National Eye Institute (NEI); National...

Recruiting

Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD (AO)

Neovascular Age-related Macular Degeneration

United States
University of Dublin, Trinity College
Motor Neurone Disease Association, UK; Irish Research Council, IE; Thierry Latran... and other collaborators

Recruiting

EEG and TMS-based Biomarkers of ALS, MS and FTD

Multiple Sclerosis | Amyotrophic Lateral Sclerosis | Frontotemporal Dementia

Ireland
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Two Treatment Regimens of 0.5 mg Ranibizumab Intravitreal Injections Guided by Functional and/or Anatomical Criteria, in Patients With Neovascular Age-related Macular Degeneration (OCTAVE)

Neovascular Age-related Macular Degeneration

Germany, Turkey, Austria, Canada, Czechia, United Kingdom, Hungary, Italy, Lithuania, Guatemala, France, Ireland, Argentina, Portugal, Spain, Sweden, Greece, Switzerland, Slovakia, Finland, Netherlands, Colombia, Mexico, Panama
NeoVista

Unknown

A Study of Strontium90 Beta Radiation With Lucentis to Treat Age-Related Macular Degeneration (CABERNET)

Macular Degeneration

United Kingdom, United States, Israel, Austria, Germany, Ireland, Peru, Spain, Switzerland
Pfizer

Completed

Ocular Safety Of Patients Receiving Macugen For Neovascular Age Related Macular Degeneration

Macular Degeneration

Greece, Italy, Slovakia, Spain, Sweden, Czech Republic, Germany, Belgium, France, Cyprus, Denmark, Ireland, Poland
Jaeb Center for Health Research
Juvenile Diabetes Research Foundation; National Eye Institute (NEI); National...

Recruiting

Evaluation of Tonabersat for DME (AN)

Diabetic Macular Edema

United States
Otsuka Pharmaceutical Development & Commercialization...

Terminated

Study to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD)

Major Depressive Disorder (MDD)

United States, Spain, Hungary, South Africa, Croatia, France, Poland, India, Canada, Sweden, Malaysia
Otsuka Pharmaceutical Development & Commercialization...
Otsuka Pharmaceutical Co., Ltd.

Completed

Brexpiprazole as Adjunctive Therapy With Major Depressive Disorder and an Inadequate Response to Previous Adjunctive Therapy

Major Depressive Disorder (MDD)

United States
Oyster Point Pharma, Inc.

Completed

Evaluation of the Efficacy and Safety of OC-01 Nasal Spray on Signs and Symptoms of Dry Eye Disease

Dry Eye Disease (DED)

United States
Regeneron Pharmaceuticals
Bayer

Completed

Vascular Endothelial Growth Factor VEGF Trap-Eye:Investigation of Efficacy and Safety in Wet Age-Related Macular Degeneration(AMD) (VIEW1)

Macular Degeneration

United States, Canada
AstraZeneca
Targacept Inc.

Completed

A Study to Assess the Long- Term Safety of TC-5214 as an Adjunct Therapy in Patients With Major Depressive Disorder

Depression | Major Depressive Disorder | MDD

United States, Puerto Rico
Allergan

Completed

Efficacy and Safety of a New Artificial Tear Formulation Compared With Systane Ultra Multidose in Participants With Dry Eye Disease

Dry Eye Disease (DED)

United States
Johns Hopkins University
Juvenile Diabetes Research Foundation; Genentech, Inc.

Completed

The Ranibizumab for Edema of the mAcula in Diabetes-2 (READ-2) Study

Diabetic Macular Edema

United States
GlaxoSmithKline

Completed

Sexual Functioning Study With Antidepressants

Depressive Disorder, Major | Major Depressive Disorder (MDD)

United States
Jaeb Center for Health Research
National Eye Institute (NEI); Allergan

Completed

Intravitreal Triamcinolone Acetonide Versus Laser for Diabetic Macular Edema (IVT)

Diabetic Macular Edema

United States
GlaxoSmithKline

Completed

Depression Study In Elderly Patients

Depressive Disorder, Major | Major Depressive Disorder (MDD)

United States
Novartis

Completed

Efficacy, Safety and Tolerability of Agomelatine in the Treatment of Major Depressive Disorder

Major Depressive Disorder (MDD)

United States
Otsuka Pharmaceutical Development & Commercialization...

Terminated

Study to Evaluate the Efficacy, Safety and Tolerability of an Oral Aripiprazole/Escitalopram Combination Therapy in Participants With Major Depressive Disorder (MDD)

Major Depressive Disorder (MDD)

Finland, Germany, Korea, Republic of, United States, Taiwan, Estonia, India, Italy, Mexico
Novartis

Completed

Efficacy, Tolerability and Safety of Dexmethylphenidate HCl Extended-Release Capsules in Children With Attention-Deficit/Hyperactivity Disorder

ADHD, ADD

United States
Abbott Medical Devices

Active, not recruiting

The CONFIDENCE Registry

Severe Aortic Stenosis | Symptomatic Degenerative Aortic Stenosis

Spain, Italy, United Kingdom, Germany, Switzerland, Czechia, Australia, Belgium, Poland
Novartis Pharmaceuticals

Completed

Observe the Effectiveness and Safety of Ranibizumab in Real Life Setting (LUMINOUS)

Diabetic Macular Edema | Retinal Vein Occlusion | Wet Age Related Macular Degeneration | Wet Age Related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion

Spain, China, Colombia, Korea, Republic of, Belgium, Greece, Japan, Russian Federation, Turkey, United Kingdom, Egypt, Germany, Australia, Canada, France, Austria, Hong Kong, Hungary, Israel, Netherlands, Peru, Singapore, Slovakia, Sl... and more
GlaxoSmithKline

Completed

Lethargic Depression Study

Epilepsy | Major Depressive Disorder (MDD)

United States
Jaeb Center for Health Research
National Eye Institute (NEI)

Completed

A Phase 2 Evaluation of Anti-VEGF Therapy for Diabetic Macular Edema: Bevacizumab (Avastin) (Bevacizumab)

Diabetic Retinopathy

United States
Santhera Pharmaceuticals

Terminated

A Phase III Double-blind Study With Idebenone in Patients With Duchenne Muscular Dystrophy (DMD) Taking Glucocorticoid Steroids (SIDEROS)

Duchenne Muscular Dystrophy (DMD)

United States, Spain, Netherlands, Sweden, Germany, France, Belgium, United Kingdom, Italy, Ireland, Switzerland, Austria, Bulgaria, Hungary, Israel
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Ranibizumab in Two "Treat and Extend" Treatment Algorithms Versus Ranibizumab As Needed in Patients With Macular Edema and Visual Impairment Secondary to Diabetes Mellitus (RETAIN)

Diabetic Macular Edema

Belgium, United Kingdom, Netherlands, Ireland, Switzerland, Italy, Hungary, France, Spain, Portugal, Poland, Czech Republic, Greece

Clinical Trials on Degenerative Disc Disease(DDD) in Ireland

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