Clinical Trials on Degenerative Diseases, Nervous System

Total 191517 results

Inonu University

Not yet recruiting

VEXUS and NGAL in the Diagnosis and Prognosis of Sepsis-associated Acute Kidney Injury

Sepsis | Acute Kidney Injury
Indonesia University

Recruiting

Comparison of Plasma Neutrophil Gelatinase-Associated Lipocalin (pNGAL) Level in De-resuscitation With Furosemide Group and Control Group

Acute Kidney Injury Due to Sepsis

Indonesia
Tel-Aviv Sourasky Medical Center

Unknown

Influenza Vaccination in Patients With Scleroderma

Influenza Vaccine in Scleroderma

Israel
Francis Corazza

Completed

Evaluation of Interleukine 6 (and Other Cytokines and Inflammatory Markers) in COVID-19 Patients With a Systemic Inflammatory Response Syndrome

COVID-19

Belgium
DR. JASSIM ALGHAITH

Unknown

The Effects of Multi-modality Physiotherapy in Delaying or Preventing COVID-19 Patient From Admitting to ICU

Covid19 | Severe Systemic Illness Respiratory Muscle Fatigue

Kuwait
Children's Hospital of Fudan University

Not yet recruiting

A Multi-Center Data System and Collaborative Network in China for Severe Infection and Sepsis Children

Critical Illness | Severe Sepsis
Australian and New Zealand Intensive Care Research...

Not yet recruiting

Restricted or Liberal Fluid for Haemodynamic Resuscitation in Sepsis (FRESHLY)

Septic Shock | Fluid Resuscitation
Medical University of Gdansk
Pomeranian Medical University Szczecin

Recruiting

The Effect of Probiotics on Systemic Inflammation and Metabolic Endotoxemia in Patients Undergoing Bariatric Surgery

Dysbiosis | Bariatric Surgery Candidate

Poland
University Hospital, Rouen

Recruiting

Comparison of Extubation Delay After Prolonged Sedation (ISOREA)

Septic Shock

France
Susan Smyth

Withdrawn

The INFUSE Trial - Intervening With Platelet Transfusions in Sepsis (INFUSE)

Sepsis | Thrombocytopenia

United States
Changzheng-Cinkate

Terminated

An Open-Label, Study to Treat Patients With Renal Allograft and Polyoma BK Viruria

Viremia | Viruria

United States
University of Roma La Sapienza

Completed

Effects of Levosimendan on Microcirculation in Septic Shock

Septic Shock

Italy
Bayer

Completed

An Study to Evaluate the Safety and Efficacy of Copanlisib in Combination With Nivolumab in Patients With Advanced Solid Tumors

Hepatocellular Carcinoma (HCC) | Non-small Cell Lung Cancer (NSCLC) | Head and Neck Squamous Cell Carcinoma (HNSCC)

United States, Canada
University of California, San Francisco

Completed

Itraconazole in Treating Patients With Biochemically Relapsed Prostate Cancer

Prostate Adenocarcinoma | Recurrent Prostate Carcinoma | Stage III Prostate Adenocarcinoma AJCC v7 | Stage I Prostate Adenocarcinoma AJCC v7 | Stage II Prostate Adenocarcinoma AJCC v7

United States
Centre Hospitalier Universitaire, Amiens

Unknown

Prevalence of Liver Fibrosis and Cirrhosis in Patients With Squamous Cell Carcinoma of the Head and Neck (fibr'HOM)

Squamous Cell Carcinoma of the Head and Neck | Liver Cirrhoses | Liver Fibroses

France
Ascension Via Christi Hospitals Wichita, Inc.
The University of Kansas School of Medicine - Wichita

Terminated

HAT for the Treatment of Sepsis Associated With NASTI

Sepsis | Necrotizing Soft Tissue Infection

United States
University Hospital Tuebingen

Withdrawn

Platelet Transfusion in Sepsis Trial

Sepsis | Thrombocytopenia
Children's Hospital Medical Center, Cincinnati
University of Cincinnati; Cloudnine Hospital, Bangalore, India

Recruiting

Topical Coconut Oil Application and Incidence of Sepsis in Neonates

Late-Onset Neonatal Sepsis

India
Sygehus Lillebaelt
Kolding Sygehus

Completed

Neutrophil Gelatinase Associated Lipocalin (NGAL) in Urine: Can This Prove to be a Biomarker for Acute Kidney Injury in Patients With Sepsis?

Septic Shock | Acute Kidney Injury | Severe Sepsis

Denmark
Hospices Civils de Lyon

Recruiting

Prodromes of Menstrual Staphylococcal Toxic Shock (IPro-CTSm)

Toxic Shock Syndrome Staphylococcal

France
Chinese PLA General Hospital

Completed

The Application of Soluble Triggering Receptor Expressed on Myeloid Cells-1 in Sepsis & Relevant Acute Kidney Injuries

Sepsis | SIRS

China
Abramson Cancer Center at Penn Medicine
Genmab

Not yet recruiting

Epcoritamab-CAR T Cells for Large B-cell Lymphomas

Lymphoma, Non-Hodgkin | High-grade B-cell Lymphoma | Refractory Diffuse Large B-cell Lymphoma | Relapsed Diffuse Large B Cell Lymphoma | Transformed Indolent Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma

United States
Qiu Lugui

Recruiting

GVM±R in Patients With Relapsed or Refractory Aggressive NHL.

Diffuse Large B-cell Lymphoma | Peripheral T Cell Lymphoma

China
Massachusetts General Hospital
Varian Medical Systems

Recruiting

Adaptive Bridging RT in R/R B-cell Lymphoma (Pre-CAR T)

Lymphoma, B-Cell | Follicular Lymphoma | Mantle Cell Lymphoma | Diffuse Large B Cell Lymphoma | Refractory Lymphoma | High-grade B-cell Lymphoma | Relapsed Cancer | Mediastinal Large B-cell Lymphoma

United States
University of Geneva, Switzerland
All India Institute of Medical Sciences, New Delhi; Swiss National Science... and other collaborators

Recruiting

Pharmacogenomic Association Study in Indian Children With Acute Lymphoblastic Leukemia (MPGx-INDALL)

Drug Effect | Pediatric Cancer | Adverse Drug Event | Drug Interaction | ALL, Childhood | Drug Toxicity | Toxicity, Drug | Relapse Leukemia

India
Yazeed Sawalha

Recruiting

Zanubrutinib in Combination With R-CHOP (ZaR-CHOP) for Newly Diagnosed Diffuse Large B-Cell Lymphoma

Diffuse Large B-Cell Lymphoma | Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma | Transformed Marginal Zone Lymphoma to Diffuse Large B-Cell Lymphoma

United States
Juno Therapeutics, a Subsidiary of Celgene

Active, not recruiting

Study Evaluating the Safety and Pharmacokinetics of JCAR017 in B-cell Non-Hodgkin Lymphoma (TRANSCEND-NHL-001)

Follicular Lymphoma | Non-Hodgkin Lymphoma | Diffuse Large B Cell Lymphoma | Primary Mediastinal B-cell Lymphoma | Mantle-cell Lymphoma

United States
Kite, A Gilead Company

Approved for marketing

Axicabtagene Ciloleucel Expanded Access Study (ZUMA-9)

Relapsed/Refractory Diffuse Large B Cell Lymphoma | Relapsed/Refractory Primary Mediastinal B Cell Lymphoma | Relapsed/Refractory Transformed Follicular Lymphoma | Relapsed/Refractory High-Grade B-Cell Lymphoma

United States
Amgen

Completed

Open Label Extension Study of Conatumumab and Ganitumab (AMG 479)

Sarcoma | Lymphoma | Colorectal Cancer | Non-Small Cell Lung Cancer | Advanced Solid Tumors | Metastatic Cancer | Solid Tumors | Carcinoid | Locally Advanced

United States, Spain, Poland
First Affiliated Hospital of Wenzhou Medical University
Second Affiliated Hospital of Nanchang University; Hrain Biotechnology Co.,...

Unknown

Anti-CD19 CAR T Infusion Combined With Allogeneic Stem Cell Transplantation for B-cell Leukemia/Lymphoma

Hematopoietic/Lymphoid Cancer | Adult Acute Lymphoblastic Leukemia in Remission | B-cell Chronic Lymphocytic Leukemia | Refractory Chronic Lymphocytic Leukemia | B-cell Adult Acute Lymphoblastic Leukemia

China
Chonbuk National University Hospital
Samsung Medical Center; Pusan National University Hospital; Chonnam National... and other collaborators

Completed

Risk Stratification of Nodal PTCL

Angioimmunoblastic T-cell Lymphoma | Peripheral T-Cell Lymphoma, Not Otherwise Specified | Anaplastic Large Cell Lymphoma, ALK-negative

Korea, Republic of
M.D. Anderson Cancer Center

Completed

A Study Of Deoxycoformycin(DCF)/Pentostatin In Lymphoid Malignancies

Chronic Lymphocytic Leukemia | Cutaneous T-cell Lymphoma | Peripheral T-cell Lymphoma

United States
Seagen Inc.

Terminated

A Safety Study of SGN-CD19B in Patients With B-cell Non-Hodgkin Lymphoma

Non-Hodgkin Lymphoma | Diffuse Large B-cell Lymphoma | DLBCL | Grade 3 Follicular Lymphoma

United States
National Cancer Institute (NCI)

Terminated

Alvespimycin Hydrochloride in Treating Patients With Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or B-Cell Prolymphocytic Leukemia

Recurrent Small Lymphocytic Lymphoma | B-cell Chronic Lymphocytic Leukemia | Prolymphocytic Leukemia | Refractory Chronic Lymphocytic Leukemia

United States
Stanford University

Completed

Rituximab After Autologous Stem Cell Transplant for Relapsed B-cell Non-Hodgkin's Lymphoma

Lymphoma | Non-Hodgkin's Lymphoma | Mantle Cell Lymphoma | Diffuse Large Cell Lymphoma | Transformed Lymphoma | Other Subtypes of B-cell Lymphoma

United States
AstraZeneca
CLL Consortium

Completed

AZD6738 First Time in Patient Multiple Ascending Dose Study

B Cell Lymphomas | 11q-deleted Relapsed/Refractory Chronic Lymphocytic Leukaemia (CLL), | Prolymphocytic Leukaemia (PLL)

United States
National Cancer Institute (NCI)

Terminated

Rituximab and Oblimersen in Treating Patients With Stage II, Stage III, or Stage IV Follicular Non-Hodgkin's Lymphoma

Stage III Grade 1 Follicular Lymphoma | Stage III Grade 2 Follicular Lymphoma | Stage III Grade 3 Follicular Lymphoma | Stage IV Grade 1 Follicular Lymphoma | Stage IV Grade 2 Follicular Lymphoma | Stage IV Grade 3 Follicular Lymphoma

United States
University of Giessen

Completed

Bendamustine Plus Rituximab Versus CHOP Plus Rituximab

Marginal Zone Lymphomas | Non-Hodgkin Lymphomas | Follicular Lymphomas | Immunocytomas | Lymphocytic Lymphomas

Germany
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of Arkansas; The Emmes Company, LLC

Completed

Intravenous Chemotherapy or Oral Chemotherapy in Treating Patients With Previously Untreated Stage III-IV HIV-Associated Non-Hodgkin Lymphoma

AIDS-related Peripheral/Systemic Lymphoma | AIDS-related Diffuse Large Cell Lymphoma | AIDS-related Diffuse Mixed Cell Lymphoma | AIDS-related Diffuse Small Cleaved Cell Lymphoma | AIDS-related Immunoblastic Large Cell Lymphoma | AIDS-related Lymphoblastic Lymphoma | AIDS-related Small Noncleaved... and other conditions

Zimbabwe, Kenya
Gazi University

Completed

Physical Deteriorations in Allo-HSCT.

Stem Cell Transplantation

Turkey
National Taiwan University Hospital

Terminated

Efficacy of Polymyxin B Hemoperfusion on Severe Sepsis Secondary to Pneumonia or Urinary Tract Infection

Sepsis

Taiwan
Jian-cang Zhou M.D.

Completed

Community-Onset Bacteremia Due to ESBL Producing E.Coli or K.Pneumoniae in China: Prevalence, Risk Factors and Prognosis

Community Acquired Infection

China
Centre Hospitalier Universitaire, Amiens
University Hospital, Rouen; University Hospital, Caen; Tourcoing Hospital; Centre... and other collaborators

Recruiting

Does High-dose Vitamin B3 Supplementation Prevent Major Adverse Kidney Events During Septic Shock? (VITAKI)

Mortality | Septic Shock | Acute Kidney Injury | Nicotinamide

France
HK Surgical, Inc.
University of California, Riverside

Not yet recruiting

Tumescent Anesthesia Antibiotic Delivery (TAAD) (TAAD)

Sepsis | Thrombosis | Surgical Site Infection
Islam Elsayed Mohamed Ahmed

Completed

Renal Arterial Resistive Index Versus Novel Biomarkers for Early Prediction of Sepsis Associated-acute Kidney Injury (RRIBIOSAKI)

Sepsis | Septic Shock | Acute Kidney Injury

Egypt
Christian Hassager

Completed

IL-6 Inhibition for Modulating Inflammation After Cardiac Arrest (IMICA)

Systemic Inflammatory Response Syndrome | Heart Arrest | Out-Of-Hospital Cardiac Arrest

Denmark
University Hospital, Bordeaux
Ministry of Health, France

Completed

Haemofiltration Study : IVOIRE (hIgh VOlume in Intensive Care) (IVOIRE)

Shock, Septic | Renal Failure, Acute

France, Belgium, Netherlands
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); Vanderbilt University

Completed

Rapid Identification and Phenotypic Susceptibility Testing for Gram-Negative Bacteremia (RAPIDS-GN)

Gram-negative Bacteremia

United States
Fondazione Italiana Linfomi - ETS

Not yet recruiting

Lifestyles Implemented-Survivorship Care Plan In Lymphoma Survivors

Classical Hodgkin Lymphoma | Primary Mediastinal Large B-cell Lymphoma (PMBCL) | Diffuse Large B Cell Lymphoma (DLBCL)

Italy
Tianjin Medical University Cancer Institute and...

Not yet recruiting

A Multicenter, Phase 2 Study Evaluating the Value of Radiotherapy in Advanced Diffuse Large B-cell Lymphoma Patients With Extranodal Involvement and Large Tumors Undergoing Immunochemotherapy for PET-CT Assessment of Complete Remission

Radiotherapy | Advanced Diffuse Large B-Cell Lymphoma | Extra-nodal Involvement, Large Mass

Clinical Trials on Degenerative Diseases, Nervous System

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