Clinical Trials on Degenerative Diseases of the Central Nervous System

Total 144032 results

University of California, Los Angeles

Recruiting

Behavioral Weight Loss Intervention Utilizing Mobile Health Technology in Hematopoietic Stem Cell Transplant Patients

Obesity | Stem Cell Transplant

United States
Assistance Publique - Hôpitaux de Paris

Unknown

Inflammatory Response to Paramyxovirus Infection in an Ex-vivo Model of Bronchial Epithelial Cells in Allogeneic HSCT Recipients (ALLOVIRO)

Stem Cell Transplantation

France
The First Hospital of Jilin University

Not yet recruiting

The Diagnostic and Prognostic Value of TAT, PIC, tPAI·C and TM in Sepsis-induced Coagulopathy

Sepsis-induced Coagulopathy
Wuhan Union Hospital, China

Unknown

The Early Coagulopathy for the Prognosis in Sepsis

Sepsis | Outcome, Fatal | Coagulopathy
Virginia Commonwealth University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Vitamin C Infusion for Treatment in Sepsis Induced Acute Lung Injury (CITRIS-ALI)

Sepsis | Acute Lung Injury

United States
Isle of Wight NHS Trust
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Long-Term Examination of Asthma From Childhood Through Adolescence

Asthma | Rhinitis | Dermatitis, Atopic | Urticaria

United Kingdom
University of California, Irvine
Ann & Robert H Lurie Children's Hospital of Chicago; Children's Hospital Los... and other collaborators

Recruiting

Exercise in Child Health (Project REACH)

Cystic Fibrosis | Sickle Cell Disease | SARS CoV 2 Infection

United States
Institute of Tropical Medicine, Belgium
KU Leuven; Institut National de Recherche Biomédicale. Kinshasa, République... and other collaborators

Completed

Clinical Decision Support in Non-typhoidal Salmonella Bloodstream Infections in Children (DeNTS)

Bloodstream Infection | Malaria,Falciparum | Severe Malaria | Salmonella Bacteremia

Belgium
Inflammatix

Completed

HostDx Sepsis in the Diagnosis and Prognosis of Emergency Department Patients With Suspected Infections: a Multicenter Pilot Study

Respiratory Tract Infections | Sepsis | Intraabdominal Infections | Urinary Tract Infections | Skin and Soft Tissue Infections

United States, Greece
Fate Therapeutics

Completed

FT500 as Monotherapy and in Combination With Immune Checkpoint Inhibitors in Subjects With Advanced Solid Tumors

Melanoma | Lymphoma | Renal Cell Carcinoma | Cervical Cancer | Head and Neck Cancer | Small Cell Lung Cancer | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | NSCLC | Advanced Solid Tumors | HER2-positive Breast Cancer | Pancreas Cancer | Urothelial Carcinoma | Merkel Cell Carcinoma | Microsatellite Instability and other conditions

United States
University of California, Davis

Active, not recruiting

A Cohort Study of the Intestinal Microbiota of Premature Infants

Necrotizing Enterocolitis | Bronchopulmonary Dysplasia | Growth Failure

United States
Cytokind, Inc.
Baylor College of Medicine; Louisiana State University Health Sciences Center... and other collaborators

Completed

Photo-Protection Trial (NB-UVB vs. Placebo) in High-risk Hospitalized COVID-19 Patients

Autoimmune Diseases | Covid19 | Corona Virus Infection | Coagulation Disorder, Blood

United States
Astra USA

Completed

An Open Study of Foscarnet Treatment of Acyclovir-Resistant Herpes Simplex Virus in Patients With the Acquired Immunodeficiency Syndrome and Other Immunodeficiencies

HIV Infections | Herpes Simplex

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Young Patients With Down Syndrome and Acute Myeloid Leukemia or Myelodysplastic Syndromes

Secondary Acute Myeloid Leukemia | Childhood Acute Erythroleukemia (M6) | Childhood Acute Megakaryocytic Leukemia (M7) | Childhood Acute Monoblastic Leukemia (M5a) | Childhood Acute Monocytic Leukemia (M5b) | Childhood Acute Myeloblastic Leukemia With Maturation (M2) | Childhood Acute Myeloblastic... and other conditions

United States, Canada, Australia, Puerto Rico
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Blinatumomab in Treating Patients With B-cell Acute Lymphoblastic Leukemia With Minimal Residual Disease

B Acute Lymphoblastic Leukemia | Philadelphia Chromosome Positive | Minimal Residual Disease | Adult Acute Lymphoblastic Leukemia in Complete Remission

United States
University of Washington
Pfizer

Completed

Inotuzumab Ozogamicin and Chemotherapy in Treating Patients With Recurrent or Refractory B-cell Acute Lymphoblastic Leukemia

Recurrent B Acute Lymphoblastic Leukemia | Refractory B Acute Lymphoblastic Leukemia | Recurrent B Lymphoblastic Lymphoma | Refractory B Lymphoblastic Lymphoma

United States
National Cancer Institute (NCI)

Terminated

FR901228 Alone or Combined With Rituximab and Fludarabine in Treating Patients With Relapsed or Refractory Low-Grade B-Cell Non-Hodgkin's Lymphoma

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Small Lymphocytic Lymphoma

United States
Universitaire Ziekenhuizen KU Leuven

Recruiting

Prospective Validation of the ADNEX Model for Discrimination Between Benign and Malignant Adnexal Masses in Pregnancy: International Ovarian Tumour Analysis in Pregnancy Study (p-IOTA) (pIOTA)

Pregnancy Related | Adnexal Mass | Adnexal Tumor | Adnexal Cyst

Belgium
Sun Yat-sen University
Fifth Affiliated Hospital, Sun Yat-Sen University; First People's Hospital... and other collaborators

Recruiting

Efficacy of Ulinastatin for Reducing Radiation-Induced Oral Mucositis in Nasopharyngeal Carcinoma Patients (UTI-RTOM-NPC)

Oral Mucositis (Ulcerative) Due to Radiation

China
Duke University
National Institute of Allergy and Infectious Diseases (NIAID)

Terminated

Effects of E-cigarettes (ECIGs) on Pulmonary Inflammation and Behavior in HIV Infected Smokers

HIV Seropositivity | Lung Inflammation

United States
Ozlem Sahin

Unknown

The Serum Angiotensin Converting Enzyme and Lysozyme Levels in Patients Non-infectious and Infectious Uveitis (uveitis)

Tuberculosis | Sarcoidosis

Turkey
Kirby Institute
Bristol-Myers Squibb; GlaxoSmithKline; Merck Sharp & Dohme LLC; Gilead Sciences; Hoffmann-La... and other collaborators

Terminated

Facial Lipoatrophy Trial: Immediate Versus Deferred Injections of Poly-L-Lactic Acid for HIV Facial Lipoatrophy

HIV Infections | HIV-Associated Lipodystrophy

Australia
Astra USA

Completed

An Open, Multicenter Study of Foscarnet Treatment of Acyclovir-Resistant Herpes Simplex Virus in Patients With the Acquired Immunodeficiency Syndrome and Other Immunodeficiencies

HIV Infections | Herpes Simplex

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Ultrasound-guided Blood Sampling Drawing for Microbiological Analysis in the Critically Ill (ECOVEN)

Infections | Sepsis | Septic Shock | Diagnosis
The First Affiliated Hospital of Soochow University

Recruiting

The Use of Eltrombopag Post HSCT in BMFS

Stem Cell Transplant Complications

China
Xiao-Jun Huang

Recruiting

CMV-TCR-T Cells for Refractory CMV Infection After HSCT

Allogeneic Hematopoietic Stem Cell Transplantation | CMV Infection

China
Universitaire Ziekenhuizen KU Leuven
Federaal Kenniscentrum voor Gezondheidszorg, Belgium

Completed

Early Administration of Vitamin C in Patients With Sepsis or Septic Shock in Emergency Departments (c-easie)

Sepsis | Septic Shock | Sepsis, Severe

Belgium
Rabin Medical Center

Active, not recruiting

Risk Factors and Treatment Outcome of Oncology Children Hospitalized in the Intensive Care Unit Due to Sepsis

Sepsis | Childhood Cancer | ICU | Oncologic Complications and Emergencies

Israel
University Medical Centre Ljubljana

Terminated

The Effect of Vitamin C, Thiamine and Hydrocortisone on Clinical Course and Outcome in Patients With Severe Sepsis and Septic Shock

Sepsis | Critical Illness | Septic Shock | Fluid Overload

Slovenia
Jianfeng Xie

Completed

ARDS Prediction Score in Critically Ill Patients in China

Septic Shock | ARDS

China
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Mosunetuzumab and Polatuzumab Vedotin for the Treatment of Patients With Relapsed or Refractory Grade 1-3a Follicular Lymphoma

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3a Follicular Lymphoma | Refractory Grade 1 Follicular Lymphoma | Refractory Grade 2 Follicular Lymphoma | Refractory Grade 3a Follicular Lymphoma

United States
Steven E. Coutre

Completed

Venetoclax and Ibrutinib in Patients With Relapsed/Refractory CLL or SLL

Recurrent Small Lymphocytic Lymphoma | Refractory Chronic Lymphocytic Leukemia | Recurrent Chronic Lymphocytic Leukemia | Refractory Small Lymphocytic Lymphoma

United States
Hamad Medical Corporation

Completed

Anakinra in the Management of COVID-19 Infection

Pneumonia | Covid19 | Corona Virus Infection | Cytokine Release Syndrome | Viral Infection

Qatar
Wake Forest University Health Sciences

Recruiting

Reducing Risk for Infective Endocarditis (PIE-B)

Bacteremia | Infective Endocarditis

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Palbociclib and Sorafenib, Decitabine, or Dexamethasone in Treating Patients With Recurrent or Refractory Leukemia

Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Recurrent Acute Lymphoblastic Leukemia | Refractory Acute Lymphoblastic Leukemia

United States
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Rituximab and LMP-Specific T-Cells in Treating Pediatric Solid Organ Recipients With EBV-Positive, CD20-Positive Post-Transplant Lymphoproliferative Disorder

EBV-Related Post-Transplant Lymphoproliferative Disorder | Monomorphic Post-Transplant Lymphoproliferative Disorder | Polymorphic Post-Transplant Lymphoproliferative Disorder | Recurrent Monomorphic Post-Transplant Lymphoproliferative Disorder | Recurrent Polymorphic Post-Transplant Lymphoproliferative... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Lenalidomide and Obinutuzumab in Treating Patients With Recurrent or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Recurrent Small Lymphocytic Lymphoma | Refractory Chronic Lymphocytic Leukemia | Recurrent Chronic Lymphocytic Leukemia | Refractory Small Lymphocytic Lymphoma

United States
National Cancer Institute (NCI)

Completed

Vorinostat in Treating Patients With Relapsed or Refractory Advanced Hodgkin's Lymphoma

Recurrent Adult Hodgkin Lymphoma | Adult Lymphocyte Depletion Hodgkin Lymphoma | Adult Lymphocyte Predominant Hodgkin Lymphoma | Adult Mixed Cellularity Hodgkin Lymphoma | Adult Nodular Sclerosis Hodgkin Lymphoma | Adult Nodular Lymphocyte Predominant Hodgkin Lymphoma | Adult Favorable Prognosis... and other conditions

United States
Ain Shams University
Misr International University

Completed

Effect of Pentoxifylline on Prognosis of Coronavirus Disease 2019 (COVID- 19) Infection

Covid19 | Corona Virus Infection | Cytokine Storm

Egypt
University of Zurich

Completed

PVP Iodine Effect on Post Debridement Bacteraemia (PJB 1)

Bacteraemia Post Debridement

Switzerland
Beth Israel Deaconess Medical Center
Genzyme, a Sanofi Company

Completed

Reduced Intensity Conditioning With Clofarabine, Antithymocyte Globulin (ATG), Total Lymphoid Irradiation (TLI) Followed by Allogeneic Stem Cell Transplant

Acute Myeloid Leukemia | Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Hodgkins Disease | Relapsed/Refractory Chronic Lymphocytic Leukemia | Relapsed Refractory Multiple Myeloma | Relapsed/Refractory Non Hodgkin's Lymphoma

United States
All India Institute of Medical Sciences, New Delhi
Postgraduate Institute of Medical Education and Research; Jawaharlal Institute... and other collaborators

Completed

Balanced Crystalloid vs. Saline in Children With Septic Shock

Shock | Septic Shock

India
Southeast University, China

Completed

Effects of Terlipressin on Renal Perfusion in Patients With Septic Shock

Septic Shock

China
Fresenius Medical Care France
Hospices Civils de Lyon

Completed

Continuous Hemodialysis With an Enhanced Middle Molecule Clearance Membrane

Septic Shock

France
Prof. Tobias Feuchtinger
European Commission; Simbec-Orion Group Ltd, Merthyr Tydfil, UK; Miltenyi Biotec... and other collaborators

Recruiting

Multivirus-specific T-cell Transfer Post SCT vs AdV, CMV and EBV Infections (TRACE)

CMV Infection | EBV Infection | Stem Cell Transplant Complications | AdV Infection

Belgium, Spain, France, Germany, Italy, Netherlands
Emory University

Completed

Videoscopic Versus Open Inguinal Lymphadenectomy for Cancer

Melanoma | Vulvar Cancer | Skin Cancer | Lymphadenopathy | Anal Cancer | Merkel Cell Carcinoma | Squamous Cell Carcinoma | Penile Carcinoma | Urethral Carcinoma | Extramammary Paget's Disease | Scrotal Carcinoma

United States
Astellas Pharma Inc
Vical

Completed

Cytomegalovirus (CMV) Vaccine in Donors and Recipients Undergoing Allogeneic Hematopoietic Cell Transplant (HCT)

Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia

United States
Centre Hospitalier Universitaire, Amiens

Recruiting

TIMP2*IGFBP7 and Transient AKI (BIOCHECK)

Septic Shock

France
Temple University

Withdrawn

RepurpoSing Old Drugs TO SuppRess a Modern Threat: COVID-19 STORM (STORM)

SARS-CoV-2 | Cytokine Storm

United States
Indonesia University

Unknown

Effect of Fluid Deresuscitation With Central Venous Pressure Target 0-4 mmHg in Septic Shock Patients

Septic Shock

Indonesia

Clinical Trials on Degenerative Diseases of the Central Nervous System

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