Clinical Trials on Dementia Moderate

Total 5606 results

Chinese University of Hong Kong

Recruiting

Impact of COVID-19 Vaccines on Cerebrovascular Health

Stroke | Brain Diseases | Brain Ischemia | Dementia | Alzheimer Disease | Venous Thromboembolism | Stroke, Ischemic | Stroke, Acute | Major Adverse Cardiovascular Event | Arterial Thromboembolism

Hong Kong
Nelly Pitteloud

Recruiting

GnRH Therapy on Cognition in Down Syndrome

Down Syndrome | Cognitive Decline | Alzheimer Disease, Early Onset | Olfaction Disorders

Switzerland
Luye Pharma Group Ltd.

Completed

A Dose-escalation Study to Evaluate the Safety, Tolerability and Pharmacokinetic of LPM3770164 in Healthy Subjects

Tardive Dyskinesia | Huntington Disease

China
National Taiwan University Hospital

Recruiting

Taiwan Associated Genetic and Nongenetic Small Vessel Disease (TAG-SVD)

Stroke | Magnetic Resonance Imaging | Fabry Disease | Cerebral Small Vessel Diseases | Cadasil | HTRA1-Related Autosomal Dominant Cerebral Angiopathy | COL4A1-Related Brain Small Vessel Disease With Haemorrhage | Next-generation Sequencing

Taiwan
Central Hospital, Nancy, France

Not yet recruiting

Hyperhomocysteinemia in Alzheimer's Disease (Hcy-MA)

Alzheimer Disease | Homocystinemia
University of Virginia

Completed

Measurement and Modification of Threat Interpretation Bias in Neurodegenerative Movement Disorders (Aims 2 & 3)

Parkinson Disease | Huntington Disease

United States
Centre Hospitalier Universitaire, Amiens

Completed

Relationship Between Alzheimer Disease and Diminution of the Three Macular Nervous Retinal Layers (RETEVAL)

Alzheimer Disease | Lewy Body Disease | Retina | Optical Coherence Tomography | Cortical Atrophy | Optical Coherence Tomography Angiography | Retinal Thickening | Retinal Nerve Fibres Layer

France
University of California, Los Angeles

Withdrawn

FDDNP Protocol for Visualizing Brain Proteinopathies to Assist in the Diagnosis of Persons With Suspected CTE and AD (FDDNP)

Suspected Chronic Traumatic Encephalopathy (CTE) or Traumatic Encephalopathy Syndrome (TES) | Suspected Alzheimer's Disease (AD)
National Institute of Neurological Disorders and...

Terminated

Brain Study of Patients With Frontal Lobe Dementia and Parkinsonian Disorders

Dementia | Alzheimer's Disease | Down's Syndrome

United States
Institute for Neurodegenerative Disorders

Terminated

Evaluation of [18F] PBR06 and PET as a Marker of Inflammation in Subjects With Neurological Conditions (PBR06)

Multiple Sclerosis | Parkinson Disease | Alzheimer Disease

United States
Centre Hospitalier Universitaire, Amiens

Completed

Study of Motor Slowing in Parkinson's Disease by a Computerized Mental Chronometry Paradigm (ERAMPPCI)

Parkinson Disease | Huntington Disease

France
Avanir Pharmaceuticals

Completed

Safety Study of AVP-923 in the Treatment of IEED (Involuntary Emotional Expression Disorder) Also Known as Pseudobulbar Affect (Episodes of Uncontrolled Crying and/or Laughter)

Stroke | Parkinson's Disease | Traumatic Brain Injury | Alzheimer's Disease

United States
National Institute on Aging (NIA)

Unknown

Amyloid Plaque and Tangle Imaging in Alzheimer's Disease and Down Syndrome

Down Syndrome | Alzheimer's Disease

United States
Vanderbilt University Medical Center
Vanderbilt Kennedy Center

Recruiting

Cholinergic Integrity in Down Syndrome in Association With Aging, Alzheimer's Disease Pathology, and Cognition

Alzheimer Disease | Down Syndrome | Down Syndrome, Partial Trisomy 21

United States
Massachusetts General Hospital

Recruiting

Treatment of Restless Legs Symptoms With Pramipexole to Improve the Outcomes of Protracted Opioid Withdrawal in OUD

Sleep Disorder | Restless Legs Syndrome | Opioid-use Disorder | Opioid Withdrawal

United States
Yu-Hsiang Wu
Vanderbilt University Medical Center; National Institute on Deafness and Other...

Recruiting

Hearing Aid and Individuals With Cognitive Disorders

Alzheimer Disease 2 Due to Apoe4 Isoform | Presbycusis, Bilateral

United States
Johns Hopkins University

Completed

Group Drum-Based Music Therapy Intervention for Parkinson's Disease/Huntington's Disease

Parkinson Disease | Huntington Disease

United States
Sociedad Española de Neumología y Cirugía Torácica

Completed

Role of Hypoxia Ans Sleep Fragmentation in Alzheimer's Disease. and Sleep Fragmentation.

Obstructive Sleep Apnea | Alzheimer's Disease

Spain
BrainCheck, Inc.

Unknown

Video Games to Track Cognitive Health

Cognitive Impairment | Dementia | Mild Cognitive Impairment | Cognitive Decline | Mild Traumatic Brain Injury | Concussion | Cognitive Changes | Acute Changes in Cognition | Acute Head Injury
Centre Hospitalier Universitaire, Amiens

Withdrawn

Characterization of the Profile of Dysarthria in Huntington's Disease, Using the Clinical Evaluation Battery of Dysarthria (Huntington)

Huntington Disease | Dysarthria
Institute for Neurodegenerative Disorders

Completed

Evaluation of [123I]MNI-420 and SPECT as a Marker of the Adenosine A2a Receptor in PD, HD and Healthy Subjects. (MNI-420)

Parkinson Disease | Huntington Disease

United States
Pfizer
Medivation, Inc.

Completed

A Phase 1, Non-Randomized, Open-Label, Single-Dose Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF 01913539] In Subjects With Severely-Impaired And Normal Renal Function

Alzheimer's Disease | Huntington's Disease

United States
Universitätsklinikum Hamburg-Eppendorf
Martini-Klinik am UKE GmbH; Universitäres Herzzentrum Hamburg-Eppendorf

Recruiting

Hamburg City Health Study - a German Cohort Study (HCHS)

Vascular Diseases | Stroke | Obesity | Cancer | Periodontal Diseases | Dementia | Coronary Heart Disease | Respiratory Disease | Health Care | Ocular Diseases

Germany
The Essence of Integrative Health and Medicine...

Not yet recruiting

Psychoneuromentalism Disorder: A Medical Condition That Affects People With Psychological Impairments From Health Issues (PNMD)

Dementia | Anxiety | Bipolar Disorder | Chronic Fatigue Syndrome | Stress Disorder | ADHD - Combined Type | Dissociative Disorder | Schizoaffective Disorder, Bipolar Type
Mayo Clinic
National Institute on Aging (NIA)

Recruiting

Molecular and Structural Imaging in Alzheimer's Disease: A Longitudinal Study

Alzheimer Disease | Alzheimer Disease, Early Onset | Amnestic Mild Cognitive Disorder | Atypical Alzheimer's Disease | Logopenic Progressive Aphasia (LPA) | Posterior Cortical Atrophy (PCA) | Amnestic Disorder | Amnestic Symptoms

United States
Fundació Institut de Recerca de l'Hospital de la...

Active, not recruiting

Efficacy of Cognitive Rehabilitation Using Virtual Reality and Computer-based Cognitive Stimulation on Cognitive Impairment Associated to Movement Disorders (CogMusT)

Parkinson Disease | Huntington Disease

Spain
Yeditepe University

Completed

Comparison of the Effect of Online Physical Exercise and Computerized Cognitive Stimulation in Patients With Alzheimer's Disease

Alzheimer Disease | Telerehabilitation | Covid-19 Pandemic | Online Physical Exercise | Computerized Cognitive Stimulation

Turkey
Centre Hospitalier Universitaire de Nīmes

Withdrawn

Florbetaben as an Amyloid Plaque Marker in Elderly Patients With Focal or Disseminated Superficial Hemosiderosis (FBB ACC)

Alzheimer Disease | Amyloid Cerebral Angiopathy

France
Rajavithi Hospital
Rajavithi Biomolecular Research Center

Withdrawn

Rajavtihi Neuronal Adult Stem Cells Project (RNASc)

Multiple Sclerosis | Parkinson's Disease | Alzheimer's Disease

Thailand
Institute for Neurodegenerative Disorders

Terminated

Evaluation of [123I]CLINDE and SPECT as a Marker of Inflammation in Subjects With PD or AD and in Healthy Subjects (CLINDE)

Multiple Sclerosis | Parkinson Disease | Alzheimer Disease | Healthy Controls

United States
Institute for Neurodegenerative Disorders

Completed

Evaluation of [18F] FEPPA and PET Imaging as a Marker of Inflammation in Subjects With Neurological Conditions

Multiple Sclerosis | Parkinson Disease | Alzheimer Disease

United States
Christian Baumann
ETH Zurich

Recruiting

Assessing the Symptomatic Benefit of Acoustic Slow Wave Enhancement in Parkinson Disease

Parkinson Disease | Mild Cognitive Impairment | Huntington Disease

Switzerland
University of Miami

Recruiting

Clinical Applications of Advanced Ophthalmic Imaging

Multiple Sclerosis | Diabetic Retinopathy | Dementia | Dry Eye Syndromes | Presbyopia | Myopia

United States
Chang Gung Memorial Hospital

Enrolling by invitation

The Relationship Between Obstructive Sleep Apnea and Alzheimer's Disease: Evidence and Effectiveness (OSA)

Mild Cognitive Impairment | Obstructive Sleep Apnea of Adult

Taiwan
University Hospital, Montpellier
Assistance Publique - Hôpitaux de Paris; University Hospital, Clermont-Ferrand and other collaborators

Terminated

In Vivo Alzheimer Proteomics (PROMARA)

Parkinson Disease | Brain Trauma | Probable Alzheimer Disease | Neurological Disease Without Cognitive Degradation | Acute Hydrocephaly

France
University of Southern California
United States Department of Defense; Northern California Institute of Research... and other collaborators

Completed

A Study of Brain Aging in Vietnam War Veterans (DOD-ADNI)

Traumatic Brain Injury | Post Traumatic Stress Disorder | Mild Cognitive Impairment | Alzheimer's Disease

United States
China Medical University Hospital

Unknown

Study of the Role of G72 in Amyotrophic Lateral Sclerosis: Biomarker Discovery and Mechanism Investigation

Parkinson's Disease | Amyotrophic Lateral Sclerosis | Alzheimer Disease
O & O Alpan LLC

Unknown

Investigating Lysosomal Storage Diseases in Minority Groups

Fabry Disease | Niemann-Pick Disease | Gaucher Disease | Pompe Disease | Lysosomal Storage Disorders

United States
Washington University School of Medicine
Genentech, Inc.

Recruiting

Mosunetuzumab Consolidation Therapy After autoSCT in r/r Aggressive B Cell Lymphoma

B Cell Lymphoma | Diffuse Large B Cell Lymphoma | High-grade B-cell Lymphoma | Transformed Lymphoma | Aggressive Lymphoma | Follicular Lymphoma Grade 3

United States
Cedars-Sinai Medical Center

Completed

Memory Disorders Registry

Parkinson Disease | Dementia | Huntington Disease | Alzheimer's Disease

United States
University of Edinburgh
NHS Lothian

Not yet recruiting

Digital App for Speech & Health Monitoring

Multiple Sclerosis | Parkinson Disease | Motor Neuron Disease | Dementia
IRCCS San Camillo, Venezia, Italy
IRCCS Centro San Giovanni di Dio Fatebenefratelli; Università Ca' Foscari Venezia

Recruiting

Exploring the Gut-Brain Axis in Ageing and Neurodegeneration (GutBrain)

Multiple Sclerosis | Healthy | Parkinson Disease | Prodromal Alzheimer's Disease

Italy
Centre Hospitalier Universitaire de Saint Etienne
Association Lyonnaise de Logistique Posthospitalière

Terminated

Sleep Apnea in Early to Mid-Stage Alzheimer's Disease (AZAP)

Alzheimer Disease | Early Onset Alzheimer Disease | Obstructive Sleep Apnea Syndromes

France
Vanderbilt University Medical Center

Not yet recruiting

Voice and Swallowing Disorders in Adults With and Without Alzheimer's Disease

Alzheimer Disease | Caregiver Burden | Dysphagia | Healthy Aging | Dysphonia
St. Joseph's Hospital and Medical Center, Phoenix
Texas Tech University

Not yet recruiting

MCLENA-2: A Phase II Clinical Trial for the Assessment of Lenalidomide in Patients With Mild Cognitive Impairment Due to Alzheimer's Disease

Cognitive Dysfunction | Neurodegenerative Disease, Hereditary | Cognitive Impairment, Mild | Amyloid Plaque | Inflammation, Brain
Azienda Ospedaliera di Perugia

Recruiting

PIPAF Platelets in the Pathogenesis of Ageing Associated Frailty (PIPAF)

Coronary Artery Disease | Diabetes Mellitus, Type 2 | Alzheimer Disease

Italy
National Institute of Neurological Disorders and...

Completed

Diagnosis and Natural History Study of Patients With Neurological Conditions

Parkinson's Disease | Dementia | Multiple System Atrophy | Alzheimer's Disease | Movement Disorder

United States
MD Stem Cells

Recruiting

Neurologic Stem Cell Treatment Study (NEST)

Stroke | Nervous System Diseases | Diabetic Neuropathies | Neurodegenerative Diseases | Cognitive Impairment | Amyotrophic Lateral Sclerosis | Dementia | Neurological Disorders | Alzheimer Disease | ALS | Traumatic Brain Injury | Cerebral Infarction | Lewy Body Disease | Cerebral Hemorrhage | Frontotemporal Dementia | Progressive... and other conditions

United States, United Arab Emirates
AIO-Studien-gGmbH
Novartis Pharmaceuticals; Assign Data Management and Biostatistics GmbH

Completed

Safety and Tolerability of Everolimus as Second-line Treatment in Poorly Differentiated Neuroendocrine Carcinoma / Neuroendocrine Carcinoma G3 (WHO 2010) and Neuroendocrine Tumor G3 - an Investigator Initiated Phase II Study (EVINEC)

Neuroendocrine Carcinoma, Grade 3 | Poorly Differentiated Malignant Neuroendocrine Carcinoma | Neuroendocrine Carcinoma, Grade 1 [Well-differentiated Neuroendocrine Carcinoma] That Switched to G3 | Neuroendocrine Carcinoma, Grade 2 [Moderately Differentiated Neuroendocrine Carcinoma]... and other conditions

Germany
Kaiser Permanente
Patient-Centered Outcomes Research Institute

Terminated

Comparative Trial of Home-Based Palliative Care (HomePal)

End Stage Liver Disease | Heart Failure | Cancer | Chronic Obstructive Pulmonary Disease | Neuromuscular Diseases | Dementia | End Stage Renal Disease

United States

Clinical Trials on Dementia Moderate

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CROs in Trinidad & Tobago

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