Clinical Trials on Demyelinating Diseases

Total 381134 results

Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI); Highlight Therapeutics

Active, not recruiting

Nivolumab and BO-112 Before Surgery for the Treatment of Resectable Soft Tissue Sarcoma

Leiomyosarcoma | Malignant Peripheral Nerve Sheath Tumor | Synovial Sarcoma | Undifferentiated Pleomorphic Sarcoma | Undifferentiated High Grade Pleomorphic Sarcoma of Bone | Myxofibrosarcoma | Stage II Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage III Soft Tissue Sarcoma of the... and other conditions

United States
Cervesi Hospital, Cattolica, Italy

Unknown

Genomic DNA in Human Blastocoele Fluid

Chromosomal Aneuploidies | Single Gene Desease

Italy
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Pembrolizumab and Chemoradiotherapy for the Treatment of Unresectable Gastroesophageal Cancer

Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Unresectable Gastroesophageal Junction Adenocarcinoma | Locally Advanced Gastroesophageal Junction Adenocarcinoma | Postneoadjuvant Therapy Stage III... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Chemoradiation and Pembrolizumab Followed by Pembrolizumab and Lenvatinib Before Surgery for the Treatment of Non-metastatic Esophageal or Esophageal/Gastroesophageal Junction Cancer

Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8 | Pathologic Stage... and other conditions

United States
National Cancer Institute (NCI)

Completed

Alvocidib, Cytarabine, and Mitoxantrone in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute Myeloblastic Leukemia Without Maturation... and other conditions

United States
National Cancer Institute (NCI)

Completed

Vorinostat in Treating Patients With Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute... and other conditions

United States
The Affiliated Hospital Of Guizhou Medical University
Affiliated Hospital of Guizhou Medical University; Chinese nursing association

Recruiting

Machine Learning-based Longitudinal Study of Post-ICU Syndrome Development Trajectory in Critically Ill Patients and Construction of Clinical Early Warning Models: a Research Protocol for Longitudinal Study

Developmental Trajectory of Patients With Post-ICU Syndrome | Development and Application of Post-ICU Syndrome Prediction Model

China
National Taiwan University Hospital

Recruiting

A Study on the Relationship Between Job Satisfaction and Retention Intentions of Emergency Room Nurses

A Study on the Relationship Between Job Satisfaction and Retention Intentions of Emergency Room Nurses

Taiwan
Universidad Nacional Autonoma de Mexico
National Council of Science and Technology, Mexico

Not yet recruiting

Efficacy of a Transdiagnostic Guided Internet-Delivered Intervention for Emotional, Trauma and Stress-Related Disorders.

Depression | Anxiety Disorders | Trauma and Stressor Related Disorders | Emotional Disorder

Mexico
Central Hospital, Nancy, France

Not yet recruiting

Evaluation of Professional Practices in the Management of Blunt Abdominal Trauma in Children in the Pediatric Emergency

Blunt Abdominal Trauma in Children | Identifying Intra Abdominal Injuries

France
Burapha University

Completed

Body Massage Oil, Facial Mask, and Ready-to-drink Jelly From Snake Fruit

Body Massage Oil From Snake Fruit | Facial Mask From Snake Fruit | Jelly From Snake Fruit

Thailand
Universitaire Ziekenhuizen KU Leuven
Federaal Kenniscentrum voor Gezondheidszorg, Belgium

Completed

Early Administration of Vitamin C in Patients With Sepsis or Septic Shock in Emergency Departments (c-easie)

Sepsis | Septic Shock | Sepsis, Severe

Belgium
University Hospital of North Norway

Completed

Laparoscopic High-Ligation Repair of Indirect Inguinal Hernias in Adults

Recurrence | Postoperative Pain | Surgery | Inguinal Hernia, Indirect
Yeshiva University
The FAR Fund

Completed

Evaluation of Regulation Focused Psychotherapy for Children (RFP-C)

Oppositional Defiant Disorder | Oppositional Defiant Disorder in Children

United States
Memorial Sloan Kettering Cancer Center

Completed

Ribavirin for Patients With Recurrent/Metastatic (R/M) Human Papillomavirus (HPV)-Related Malignancies

Human Papillomavirus (HPV)-Related Malignancies | Recurrent/Metastatic (R/M) Human Papillomavirus (HPV)-Related Malignancies

United States
University of Regensburg

Completed

OFC rTMS in Emotionally Unstable and Depressed Patients (ORIENT)

Depression | Personality Disorder, Borderline | Personality Disorder; Unstable

Germany
Rabin Medical Center

Active, not recruiting

Risk Factors and Treatment Outcome of Oncology Children Hospitalized in the Intensive Care Unit Due to Sepsis

Sepsis | Childhood Cancer | ICU | Oncologic Complications and Emergencies

Israel
Iris Sommer
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); Ziekenhuis... and other collaborators

Completed

Raloxifene Augmentation in Patients With a Schizophrenia Spectrum Disorder (RAPSODI)

Schizophrenia | Schizoaffective Disorder | Schizophreniform Disorder | Psychosis NOS

Netherlands
Santo Spirito Hospital, Italy

Completed

PENG-block Versus FIB-block in Emergency Room

Pain Relief in Proximal Femoral Fracture

Italy
Juntendo University

Completed

Correlation Between Cognitive Function and Relapse of Schizophrenia Regarding Dose Reduction

Schizophrenia Relapse
University of Pennsylvania

Completed

CURE Addiction Center of Excellence: Brain Mechanisms of Relapse and Recovery (fMRI CURE)

Prescription Opiate/Medication Dependence

United States
José A. Pereira

Completed

Long-term Follow-up of Prophylactic Mesh Reinforcement After Emergency Laparotomy.

Prevention of Incisional Hernia in Emergency Surgery
Assiut University

Unknown

Histopathological Evaluation of Product of Conception in Sporadic and Recurrent Abortions

Recurrent Abortion
Yale University
National Institute of Mental Health (NIMH)

Completed

Riluzole Augmentation in Treatment-refractory Obsessive-compulsive Disorder

Obsessive-compulsive Disorder | Ocd

United States
Queen Mary University of London
Johns Hopkins University; American University of Beirut Medical Center; Medical... and other collaborators

Completed

Phone-Delivered Psychological Intervention (t-CETA) for Mental Health Problems in 8-17 Year-Old Syrian Refugee Children (t-CETA)

Depression | PTSD | Anxiety | Conduct Disorder | Oppositional Defiant Disorder

Lebanon
Centre Hospitalier Princesse Grace
Pfizer; Centre Scientifique de Monaco

Completed

An Incitative Multifaceted PROcedure for Pneumococcal Vaccination at the Emergency Department (IMPROVED)

Pneumococcal Infections

France, Monaco
University Hospitals Cleveland Medical Center

Completed

A Concierge Model of CAE Plus LAI in Individuals With Schizophrenia at Risk for Treatment Non-adherence and Homelessness (CAL-C)

Psychotic Disorders | Schizophrenia | Schizoaffective Disorder | Medication Adherence | Medication Non-Adherence

United States
Sunnybrook Health Sciences Centre
Centre for Addiction and Mental Health; Canadian Institutes of Health Research... and other collaborators

Completed

Physical Exercise in OCD: Treatment Efficacy, Additive Benefits to CBT, and Cognitive Correlates of Change

Obsessive-Compulsive Disorder | Cognition Disorders

Canada
Technische Universität Dresden
Charite University, Berlin, Germany; University Medicine Greifswald; Ruhr University... and other collaborators

Completed

Providing Tools for Effective Care and Treatment of Anxiety Disorders (PROTECT-AD)

Social Anxiety Disorder | Panic Disorder | Agoraphobia | Specific Phobias

Germany
Lehigh Valley Hospital

Completed

The Emergency Department Stopping Elderly Accidents, Deaths and Injuries Program (ED-STEADI)

Accidental Falls | Falling Injury | Other and Unspecified Fall on Same Level

United States
Mount Sinai Hospital, Canada

Unknown

Lithium Therapeutic Drug Monitoring; Once Daily Vs Twice Daily Dosing and the Impact of Kidney Function

Bipolar Disorder | Major Depressive Disorder

Canada
Korea University Anam Hospital
Samsung Medical Center; Pusan National University Hospital; Chonnam National... and other collaborators

Unknown

Design and Methods of the Mood Disorder Cohort Research Consortium (MDCRC) Study

Mood Disorders | Bipolar Disorder | Major Depressive Disorder

Korea, Republic of
University Medical Centre Ljubljana

Terminated

The Effect of Vitamin C, Thiamine and Hydrocortisone on Clinical Course and Outcome in Patients With Severe Sepsis and Septic Shock

Sepsis | Critical Illness | Septic Shock | Fluid Overload

Slovenia
Technical University of Munich

Completed

Differences in Frail and Non-frail Critically-ill Patients in Functional Outcomes (DEFAULT)

Critical Illness | Frailty | Rehabilitation | Critical Care | Intensive Care Unit | Exercise Therapy | Outcome Assessment | Physical and Rehabilitation Medicine

Germany
University Hospital, Montpellier

Completed

Deep Electrical Neuromodulation in Obsessive-compulsive Disorder (NEP-TOC)

Obsessive-compulsive Disorder (OCD)

France
Benha University

Completed

Sildenafil Citrate and Recurrent Abortion

Recurrent Abortion
University of California, Los Angeles

Completed

Delivery of Anxiety Disorder Treatment in Addictions Centers

Anxiety Disorders | Substance Use Disorders

United States
London School of Hygiene and Tropical Medicine
Addis Ababa University

Completed

RISE (Rehabilitation Intervention for People With Schizophrenia in Ethiopia) (RISE)

Schizophrenia | Schizoaffective Disorder | Schizophreniform Disorder | Schizophrenia Spectrum Disorder

Ethiopia
Policlinico Hospital

Completed

Antifungal Prophylaxis in Intensive Care Unit (ICU) Patients

Critical Illness | Surgery | Fungal Prophylaxis | Candida Infection

Italy
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Completed

Combination of Disulfiram Plus Naltrexone to Treat Both Cocaine- and Alcohol-dependent Individuals - 1

Alcoholism | Alcohol-Related Disorders | Cocaine-Related Disorders

United States
Jianfeng Xie

Completed

ARDS Prediction Score in Critically Ill Patients in China

Septic Shock | ARDS

China
University of Texas Southwestern Medical Center
Stanley Medical Research Institute

Completed

Study Using Pregnenolone to Treat Bipolar Depression

Bipolar Disorder | Major Depressive Disorder

United States
Otsuka Pharmaceutical Development & Commercialization...
Otsuka Pharmaceutical Co., Ltd.

Completed

Brexpiprazole (OPC-34712) as an Adjunctive Treatment in Adults With Major Depressive Disorder and Anxiety Symptoms

Anxiety | Major Depressive Disorder

United States
St. Joseph's Healthcare Hamilton

Unknown

Partnership in Medication Management (PIMM) in Patients With Mood Disorders (PIMM)

Bipolar Disorder | Major Depressive Disorder

Canada
Inflexxion, Inc.
National Institute on Drug Abuse (NIDA)

Completed

Field Trial of a Relapse Prevention Program for Adolescents Receiving Substance Use Treatment

Substance-Related Disorders

United States
Islamic Azad University, Marvdasht

Completed

Music Therapy in Obsessive Compulsive Disorder

Depression | Obsessive-Compulsive Disorder | Anxiety

Iran, Islamic Republic of
Hospital de Clinicas de Porto Alegre

Unknown

Attention Retraining for Anxiety Disorder Patients Resistent to Antidepressants

Generalized Anxiety Disorder | Social Anxiety Disorder | Panic Disorder

Brazil
University of California, Los Angeles
University of Colorado, Boulder

Completed

Mindfulness-Based Cognitive Therapy for Perinatal Women With Mood Disorders (MBCT)

Bipolar Disorder | Major Depressive Disorder

United States
Janssen-Cilag International NV

Completed

A Study of Relapse Prevention and the Effectiveness of Long-acting Injectable Risperidone and Quetiapine Tablets in the Treatment of Patients With Schizophrenia or Schizoaffective Disorder

Psychotic Disorders | Schizophrenia

France, Poland, Germany, Spain, Slovenia, Bulgaria, Romania, Israel, Greece, Sweden, Turkey, Czech Republic, Hungary, Lithuania, Latvia, Portugal, Croatia, Slovakia, Austria, United Kingdom, Estonia, Ireland, Denmark, Saudi Arabia
University Hospital, Basel, Switzerland

Completed

Pharmacological Interaction Between Clonidine and Methylenedioxymethamphetamine (MDMA)

Substance-Related Disorders | Amphetamine-Related Disorders | Mood Disorder

Switzerland

Clinical Trials on Demyelinating Diseases

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Uganda

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations