Clinical Trials on Depression Severe in Japan

Total 134 results

Takeda

Completed

A Study of TAK-019 in Healthy Japanese Adults (COVID-19)

Prevention of Infection Disease Caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)

Japan
Rohto Pharmaceutical Co., Ltd.

Completed

An Exploratory Study of ADR-001 in Patients With Severe Pneumonia Caused by SARS-CoV-2 Infection (COVID-19)

Severe Acute Respiratory Syndrome Coronavirus 2

Japan
Kyowa Kirin Co., Ltd.

Completed

A Phase 2 Clinical Study of KHK4827

Moderate to Severe Plaque Psoriasis

Japan
Takeda

Completed

Long-Term Extension Study of Lu AA21004 in Participants With Major Depressive Disorder

Major Depressive Disorder

Japan
Mochida Pharmaceutical Company, Ltd.
Pfizer

Completed

A Study of MD-120 in Patients With Depression

Major Depressive Disorder

Japan
Takeda

Completed

Efficacy Study of Vortioxetine (Lu AA21004) for Treatment of Major Depressive Disorder

Major Depressive Disorder

Japan
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Effexor XR in Elderly Patients With Major Depression.

Depression

Japan
Medtronic - MITG

Completed

PRediction of Opioid-induced Respiratory Depression In Patients Monitored by capnoGraphY (PRODIGY)

Respiratory Depression

United States, Japan, Spain, Singapore, Germany, Netherlands, France
Eli Lilly and Company

Completed

A Fixed Dose Study of Adjunctive Treatment to Antidepressant Therapy for Adults With Major Depressive Disorder

Major Depressive Disorder

United States, South Africa, Poland, Ukraine, Japan, Russian Federation, Latvia
Hoffmann-La Roche

Completed

MARIGOLD Study: A Study of RO4917523 Versus Placebo as Adjunctive Therapy in Patients With Major Depressive Disorder and an Inadequate Response to Ongoing Antidepressant Therapy

Major Depressive Disorder

Germany, United States, Taiwan, Mexico, Poland, Russian Federation, Chile, Japan, Romania
Takeda

Completed

A Phase 3 Study of Lu AA21004 in Patients With Major Depressive Disorder

Major Depressive Disorder

Japan
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Venlafaxine ER Phase 3 Study for Major Depressive Disorder (MDD)

Major Depressive Disorder

Japan
Eli Lilly and Company

Completed

A Study of Flexible or Fixed Dose LY2216684 as Adjunctive Treatment for Participants With Major Depressive Disorder Who Have Had a Partial Response to Selective Serotonin Reuptake Inhibitor (SSRI) Treatment

Major Depressive Disorder (MDD)

United States, Puerto Rico, Finland, Japan, Slovakia, Czechia, Croatia
Bristol-Myers Squibb

Completed

Japanese Phase 1 Multiple Ascending Dose (MAD) Study

Depression

Japan
Asahi Kasei Pharma Corporation

Completed

Study of HC-58 in Upper Limb Hemiplegic Patients After Stroke

Severe Upper Limb Hemiplegia

Japan
Naurex, Inc, an affiliate of Allergan plc

Terminated

Study of Monotherapy Rapastinel in the Prevention of Relapse in Patients With Major Depressive Disorder (MDD)

Depressive Disorder, Major

United States, Poland, Hungary, Japan, Slovakia
Astellas Pharma Inc

Completed

Study to Evaluate the Effects of Switching Different Strength Forms of FK949E in Bipolar Disorder Patients With Major Depressive Episodes

Bipolar Depression

Japan
Pfizer

Completed

Study Evaluating Desvenlafaxine Succinate Sustained Release (DVS SR) in the Treatment of Major Depressive Disorder

Major Depressive Disorder

United States, Japan
Janssen Research & Development, LLC

Terminated

A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy

Depressive Disorder, Major

United States, Korea, Republic of, Malaysia, Poland, Finland, Chile, Argentina, Slovakia, Ukraine, Denmark
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Effexor XR for Major Depression.

Depression

Japan
Boehringer Ingelheim

Completed

A Study to Test the Effect of Different Doses of BI 1358894 and Quetiapine in People With Depression

Depressive Disorder, Major

Spain, United States, Canada, Germany, Japan, Argentina, Hungary, France, Australia, Bulgaria, Czechia, Poland, Russian Federation, Slovakia
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Efficacy and Safety of JNJ-42847922 as Adjunctive Therapy to Antidepressants in Adult Participants With Major Depressive Disorder Who Have Responded Inadequately to Antidepressant Therapy

Depressive Disorder, Major

United States, Bulgaria, Ukraine, Russian Federation, Germany, Finland, Japan, France
National Center of Neurology and Psychiatry, Japan

Completed

Japan Unified Protocol Clinical Trial for Depressive and Anxiety Disorders (JUNP Study)

Anxiety Disorders | Depressive Disorders

Japan
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating Long-Term Safety of Effexor XR in Patients With Major Depression.

Depression

Japan
AstraZeneca

Terminated

A Study to Assess the Safety and Effect of TC-5214 in Patients With Major Depressive Disorder.

Major Depressive Disorder

United States, Estonia, Japan, Finland, India
Novartis Pharmaceuticals

Terminated

Study of Efficacy and Safety of MIJ821 in Addition to Comprehensive Standard of Care on the Rapid Reduction of Symptoms of Major Depressive Disorder in Subjects Who Have Suicidal Ideation With Intent

Major Depressive Disorder With Suicidal Ideation With Intent

Taiwan, Spain, Germany, Netherlands, Turkey, Mexico, United States, Malaysia, Poland, Canada, Japan, Russian Federation, Argentina, Brazil
Sunovion

Completed

Lurasidone HCI - A 6-week Phase 3 Study of Patients With Bipolar I Depression (PREVAIL3)

Bipolar Depression

United States, Canada, Colombia, Czech Republic, India, Japan, Lithuania, Peru, Slovakia, Ukraine
Novartis Pharmaceuticals

Completed

An Extention Study of Safety of Canakinumab in Japanese Patients With Periodic Fever Syndromes

Periodic Fevers Syndrome

Japan
Institute for Health Economics and Policy, Japan
Senzoku Stress Coping Support Office

Recruiting

Schema Therapy for Chronic Depression

Dysthymic Disorder | Chronic Depressive Disorder

Japan
GlaxoSmithKline

Completed

Repeat Dose Study of Controlled-Release Paroxetine Tablets and Immediate-Release Paroxetine Tablets in Healthy Japanese Male Subjects

Depressive Disorder

Japan
GlaxoSmithKline

Completed

Single Dose Study of Controlled-Release Paroxetine Tablets in Healthy Japanese Male Subjects

Depressive Disorder

Japan
Takeda

Completed

Efficacy and Safety Study of Vortioxetine (Lu AA21004) for Treatment of Major Depressive Disorder

Depressive Disorder, Major

Taiwan, Germany, Hong Kong, Poland, Malaysia, Romania, Serbia, Ukraine, Japan, Finland, Latvia, Croatia, India, Korea, Republic of, Philippines, Russian Federation
Sunovion

Completed

Lurasidone - A 24-week Extension Study of Patients With Bipolar I Depression

Bipolar Depression

United States, Canada, Czech Republic, India, Lithuania, Peru, South Africa, France, Poland, Romania, Russian Federation, Ukraine, Colombia, Slovakia, Japan
Oizumi Hospital

Unknown

Benefits of Switching Antidepressants Following Early Nonresponse

Depression

Japan
Astellas Pharma Inc

Completed

A Survey on Quetiapine Extended-release Tablets in Patients With Depression in Bipolar Disorder

Depression | Bipolar Disorder

Japan
Novartis Pharmaceuticals

Completed

Safety and Tolerability and Efficacy of LCZ696 in Japanese Severe Hypertensive Patients

Severe Hypertension

Japan
Kyorin University

Completed

MicroRNA Expression in Human Blood Serum and Vitreous Body

MicroRNA Expression Profile in Human Vitreous

Japan
AstraZeneca
Amgen

Completed

Long-term Safety of Tezepelumab in Japanese Subjects With Inadequately Controlled Severe Asthma (NOZOMI)

Severe Asthma

Japan
Kyorin University

Completed

MicroRNA Expression Profile in Human Vitreous of Patients With Various Vitreoretinal Diseases Requiring Vitrectomy

MicroRNA Expression Profile in Human Vitreous of Various Vitreoretinal Diseases

Japan
AstraZeneca

Completed

A Study to Assess Safety,and Tolerability of 2 Doses of AZD9773 (CytoFab™) in Japanese With Severe Sepsis/Septic Shock

Septic Shock | Severe Sepsis

Japan
Shiga University
Merck Sharp & Dohme LLC; Koka city

Unknown

Night in Japan Home Sleep Monitoring Study (NinJaSleep)

Depression | Sleep Initiation and Maintenance Disorders

Japan
Novartis Pharmaceuticals

Completed

Open-label, Multi-center Protocol to Provide QTI571 to PAH Patients Who Participated in the Extension Study (A2301E1) in Japan

Severe Pulmonary Arterial Hypertension

Japan
National Center of Neurology and Psychiatry, Japan

Completed

Happy Nurse Project: Lifestyle Interventions to Maintain Healthy Mental State in Hospital Nurses (HNP)

Depressive Disorder | Anxiety Disorders

Japan
Medico's Hirata Inc.

Terminated

Safety and Efficacy of SYM-SV/DS-002 in Patients With Severe Aortic Stenosis

Severe Aortic Stenosis

Japan
Kyowa Kirin Co., Ltd.

Active, not recruiting

A Phase 3 Study of KHK4827 in Patients With Systemic Sclerosis

Moderate to Severe Systemic Sclerosis

Japan
Center for Supporting Hematology-Oncology Trials
Bayer

Completed

Comparing Ciprofloxacin (CPFX) With Cefepime (CFPM) in Febrile Neutropenic Patients With Hematologic Diseases

Febrile Neutropenia

Japan
Novartis Pharmaceuticals

Active, not recruiting

Combination of Eltrombopag With Immunosuppressive Therapy in East-Asian Patients With Severe Aplastic Anemia (REACTS)

Severe Aplastic Anemia (SAA)

Japan, Korea, Republic of, China, Taiwan
Pulmonx Corporation

Recruiting

Zephyr Valve Japan Post-Marketing Surveillance

Emphysema | COPD | Severe Emphysema

Japan
Institut de Recherches Internationales Servier

Completed

Efficacy and Safety of 3 Doses of S47445 Versus Placebo in Patients With Alzheimer's Disease at Mild to Moderate Stages With Depressive Symptoms

Alzheimer's Disease

Brazil, South Africa, Chile, Hungary, Bulgaria, Czechia, Germany, Japan, Mexico, Poland, Russian Federation, Slovakia
Eli Lilly and Company

Completed

Olanzapine Treatment of Patients With Bipolar I Disorder

Depression, Bipolar

China, Korea, Republic of, Japan

Clinical Trials on Depression Severe in Japan

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