- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01674023
MicroRNA Expression Profile in Human Vitreous of Patients With Various Vitreoretinal Diseases Requiring Vitrectomy
March 31, 2015 updated by: Kazunari Hirota, Kyorin University
MicroRNAs are important regulators of many cellular functions but their expression profile in human vitreous is still unclear.
Aim of this study is to investigate microRNA expression profile by PCR in human vitreous of patients with various vitreoretinal disorders and compare with that of patients with macular holes which are suggested to be similar to that of healthy subjects.
Study Overview
Status
Completed
Study Type
Observational
Enrollment (Actual)
8
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
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Tokyo
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Mitakasi Sinkawa6-20-2, Tokyo, Japan, 181-8611
- Kyorin University School of Medicine
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
- Older Adult
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Sampling Method
Non-Probability Sample
Study Population
Pateints undergoing vitrectomy for various vitreoretinal disesases
Description
Inclusion Criteria:
- any patients undergoing vitrectomy for various vitreoretinal diseases
Exclusion Criteria:
- previously vitrectomized eyes
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
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human vitreous, human blood serum, PCR
human vitreous and blood serum sampling, PCR 1ml of human vitreous and 3ml of human blood serum of patients with various vitreoretinal diseases |
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
MicroRNA expression profile in human vitreous investigated by PCR
Time Frame: 1month
|
1month
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
August 1, 2012
Primary Completion (Actual)
December 1, 2014
Study Registration Dates
First Submitted
August 23, 2012
First Submitted That Met QC Criteria
August 27, 2012
First Posted (Estimate)
August 28, 2012
Study Record Updates
Last Update Posted (Estimate)
April 1, 2015
Last Update Submitted That Met QC Criteria
March 31, 2015
Last Verified
March 1, 2015
More Information
Terms related to this study
Other Study ID Numbers
- No.518
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on MicroRNA Expression Profile in Human Vitreous of Various Vitreoretinal Diseases
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Kyorin UniversityCompletedMicroRNA Expression Profile in Human VitreousJapan