Clinical Trials on Depressive Disorder, Major

Total 143662 results

Zylorion Health

Withdrawn

Repeated Intranasal Esketamine Plus Almond Therapy in Participants With Treatment Resistant Depressive Disorder - 3 Month Extension Study (ZYL-730-02)

Treatment Resistant Major Depressive Disorder
William Coryell

Terminated

Cytokines, PUFA Tissue Concentrations and Treatment Selection in Antenatal MDD

Major Depressive Disorder in Pregnancy
William Coryell

Terminated

Open Trial Determining Antidepressant Effects of Omega-3 Supplementation During Pregnancy

Major Depressive Disorder in Pregnancy
Hoffmann-La Roche

Completed

A Study of the Safety, Tolerability, and Pharmacokinetics of Multiple-Ascending Dose Basimglurant in Healthy Subjects and in Patients With Major Depressive Disorder (MDD)

Major Depressive Disorder, Healthy Volunteer

United States
Pfizer

Completed

Phase 1 Study To Test the Bioequivalence Between Two 25 mg Tablets vs. One 50 mg Tablet Under Fast/Fed Condition and Evaluate Food Effect of Desvenlafaxine Succinate Sustained Release (DVS SR)

Depression - Major Depressive Disorder

Belgium
Taipei Veterans General Hospital, Taiwan

Recruiting

Dorsomedial Prefrontal Neuromodulation in Treatment-resistant Depression

Major Depressive Disorder | Treatment-resistant Depression

Taiwan
Taipei Veterans General Hospital, Taiwan

Recruiting

Low-dose Ketamine Infusion Among Adolescents With Treatment-resistant Depression

Major Depressive Disorder | Treatment-resistant Depression

Taiwan
National Institute of Mental Health (NIMH)
Taisho Pharmaceutical Co., Ltd.

Recruiting

Antidepressant Effects of TS-161 in Treatment-Resistant Depression

Depression | Major Depressive Disorder | Treatment-Resistant Depression

United States
Medical University of Gdansk
Perception Neuroscience

Enrolling by invitation

Observation of Safety and Tolerability Within 1 Year of the Use of R-ketamine / Placebo in Drug-resistant Depression

Major Depressive Disorder | Treatment-Resistant Depression

Poland
Mclean Hospital
Massachusetts General Hospital; Pfizer

Terminated

Functional and Neurochemical Correlates of Treatment Response in Major Depressive Disorder

Treatment-Resistant Depression

United States
Zylorion Health

Terminated

Repeated Intranasal Esketamine Plus Almond Therapy in Patients With Treatment Resistant Depression (ZYL-730-01)

Treatment Resistant Major Depressive Disorder

Canada
Bo Hu
Patient-Centered Outcomes Research Institute

Completed

ELEKT-D: Electroconvulsive Therapy (ECT) vs. Ketamine in Patients With Treatment Resistant Depression (TRD) (ELEKT-D)

Depression | Major Depressive Disorder | Treatment Resistant Depression | Ketamine | Psychiatric Disorder | Unipolar Depression | Major Depressive Episode | Electroconvulsive Therapy | ECT

United States
Lukas Pezawas

Recruiting

Add-on Therapy With Edupression.Com® on Therapy Resistant Depressive Patients Treated With Nasal Esketamine Spray (Esketamin+)

Major Depressive Disorder | Therapy Resistant Depression

Austria
Ruijin Hospital

Terminated

Remotely Programmed Deep Brain Stimulation of the Bilateral Habenula for Treatment- Resistant Major Depression: An Open Label Pilot Trial

Treatment Resistant Major Depressive Disorder

China
University Health Network, Toronto
Centre for Addiction and Mental Health

Recruiting

Psilocybin-Assisted Psychotherapy for Treatment-Resistant Depression: Comparing One Versus Two Doses of Psilocybin (PSI-1V2)

Depression | Mood Disorders | Major Depressive Disorder | Treatment-Resistant Depression

Canada
Samsung Medical Center

Not yet recruiting

Clinical Effectiveness of Choline Alphoscerate for Older Adults With Major Depression and Subjective Memory Complaints (CHOLDEPS)

Major Depression
University of Copenhagen

Terminated

The Effect of Exercise on Depressive Symptoms in Unmedicated Patients (DEMOII)

Major Depression

Denmark
University of Sao Paulo General Hospital

Suspended

Selenium as Augmentation Treatment for Sertraline Resistant Major Depression

Major Depression

Brazil
Charite University, Berlin, Germany
NeuroCure Clinical Research Center, Charite, Berlin

Completed

Mineralocorticoid Receptor, NMDA Receptor and Cognitive Function in Depression (MISO)

Major Depression

Germany
ElMindA Ltd
Sheba Medical Center; Hebrew University of Jerusalem

Unknown

Prediction of SSRI Treatment in Major Depression.

Major Depression

Israel
University Hospital, Bonn

Completed

Deep Brain Stimulation of the Superolateral Branch of the Medial Forebrain Bundle (slMFB) for the Treatment of Refractory Major Depression (FORESEEII)

Major Depression

Germany
Institut National de la Santé Et de la Recherche...

Unknown

Assessment of Hedonic and Motivational States in Major Depression ( MOODDIS) (MOODDIS)

Major Depression
University of Michigan

Completed

Psychotherapeutic Text Messaging for Depression Pilot Study (TEXT4U)

Major Depression

United States
Hadassah Medical Organization

Completed

Evaluation of the Deep TMS H-Coil in the Treatment of Major Depression- Augmentation of Antidepressant Medication

Major Depression

Israel
National Institute of Mental Health (NIMH)
National Center for Complementary and Integrative Health (NCCIH)

Completed

Treatment of Major Depression With St. John's Wort (Hypericum)

Major Depression

United States
Cedars-Sinai Medical Center
National Institute of Mental Health (NIMH); Massachusetts General Hospital

Completed

Omega-3 Fatty Acids for Treating Adults With Major Depression

Depression

United States
National Institute of Mental Health (NIMH)

Completed

Antidepressant Effects of NR2B in Major Depression

Major Depression

United States
Centre de Recherche de l'Institut Universitaire...
Pfizer

Unknown

Effect of Antidepressants on White Matter Structure

Major Depression

Canada
Fundació Institut de Recerca de l'Hospital de la...

Terminated

Fluoxetine Versus Fluoxetine Plus DU125530 in Major Depressive Disorder

Major Depression

Spain
Shalvata Mental Health Center
Brainsway

Completed

Evaluation of Deep Transcranial Magnetic Stimulation (TMS) H-Coil in the Treatment of Major Depression

Major Depression

Israel
National Institute of Mental Health (NIMH)

Completed

Clinical Trial of Memantine for Major Depression

Depression

United States
National Institute of Mental Health (NIMH)

Completed

Examination of a Soy-Based Supplement for Major Depression

Depression

United States
National Center for Complementary and Integrative...

Completed

PUFA Augmentation in Treatment of Major Depression

Major Depression

United States
Hillerod Hospital, Denmark
Wyeth is now a wholly owned subsidiary of Pfizer; Tvergaards Foundation

Terminated

Trial of Pindolol Augmentation in Venlafaxine Treated Patients With Major Depression

Major Depression

Denmark
Hillerod Hospital, Denmark
Medicon Valley Academy

Completed

Transcranial Magnetic Stimulation (rTMS) Accelerates the Response to Escitalopram in Major Depression

Major Depression

Denmark
University Health Network, Toronto

Completed

Testosterone and Major Depression

Major Depression

Canada
Section for Affective Disorders; Northern Stockholm...
Karolinska Institutet

Completed

The Effect of Psilocybin on MDD Symptom Severity and Synaptic Density (PSIPET)

Depression | Major Depressive Disorder

Sweden
Massachusetts General Hospital

Active, not recruiting

Mechanism of Action of Transcranial Magnetic Stimulation

Depression | Major Depressive Disorder

United States
Shalvata Mental Health Center
Beer Yaakov Mental Health Center

Unknown

Neuromarkers Identification in Major Depressive Disorder Based on Monitoring Measures

Depression

Israel
Centre Hospitalier Rouffach

Recruiting

Added Value of a Neuroendocrine Test Battery in the Response to Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment (Endo-rTMS)

Major Depression

France
National Institute of Mental Health (NIMH)

Completed

Antidepressant Effects of the Glycine Receptor Antagonist AV-101 (4-chlorokynurenine) in Major Depressive Disorder

Major Depression

United States
Baylor College of Medicine
National Alliance for Research on Schizophrenia and Depression; National Center...

Completed

Research Study for Major Depressive Disorder: Investigation of Glutamate Medications

Major Depression

United States
Capital Medical University

Completed

Comparison of Venlafaxine and Fluoxetine in the Treatment of Postmenopausal Women With Major Depression

Major Depression

China
Capital Medical University

Completed

Effectiveness Study of Mirtazapine Combined With Paroxetine in Major Depressive Patients Without Early Improvement

Major Depression

China
Indiana University School of Medicine
Eli Lilly and Company

Completed

Study of Brain Response to Emotional Pictures Using a fMRI While on Duloxetine

Major Depression

United States
Mclean Hospital
National Alliance for Research on Schizophrenia and Depression

Unknown

Functional Brain Imaging Study of Response to Repetitive TMS (rTMS) Treatment of Major Depression

Major Depression

United States
University Hospital Tuebingen

Completed

Long-term Bilateral Theta Burst Stimulation for the Treatment of Major Depression (TheBuS_D)

Major Depression

Germany
National Institute of Mental Health (NIMH)

Completed

Lexapro and Pramipexole and to Treat Major Depression

Major Depression

United States
University Hospital, Bonn
Medtronic

Completed

Deep Brain Stimulation for Treatment-Refractory Major Depression

Depression

Germany
Massachusetts General Hospital

Completed

Computerized Information-Processing Bias Retraining in Depressed Adolescents

Major Depression

United States

Clinical Trials on Depressive Disorder, Major

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