Clinical Trials on Depressive Disorder, Treatment-Resistant

Total 12768 results

  • Lawson Health Research Institute
    University Health Network, Toronto; Sunnybrook Health Sciences Centre; Canadian... and other collaborators
    Completed
    Patient-Centred Innovations for Persons With Multimorbidity - Ontario (PACEinMM-ON)
    Depression | Heart Failure | Stroke | Hypertension | Cardiovascular Disease | Diabetes | Ulcer | Cancer | Arthritis | Rheumatoid Arthritis | Musculoskeletal Pain | Asthma | Gastroesophageal Reflux | Dementia | Anxiety | HIV | Crohn's Disease | Osteoporosis | Ulcerative Colitis | Chronic Obstructive Pulmonary Disease (COPD) | Hyperlipi... and other conditions
    Canada
  • Université de Sherbrooke
    Canadian Institutes of Health Research (CIHR); Western University, Canada; Agence...
    Completed
    Patient-Centred Innovations for Persons With Multimorbidity - Quebec (PACEinMM-QC)
    Depression | Heart Failure | Stroke | Hypertension | Cardiovascular Disease | Diabetes | Ulcer | Cancer | Arthritis | Rheumatoid Arthritis | Musculoskeletal Pain | Asthma | Gastroesophageal Reflux | Dementia | Anxiety | HIV | Crohn's Disease | Osteoporosis | Ulcerative Colitis | Chronic Obstructive Pulmonary Disease (COPD) | Hyperlipi... and other conditions
    Canada
  • Esther Soler
    Not yet recruiting
    Identification of Biomarkers for the Study of the Diabetic Foot and Evolution. (SCFOOT)
    Diabetes Mellitus | Diabetic Foot | Metabolic Syndrome | Sarcopenia | Neuropathy, Diabetic | Vascular Disease, Peripheral
  • Barts & The London NHS Trust
    Terminated
    CGM (Continuous Glucose Monitoring) Use in Diagnosis of Spontaneous and Reactive Hypoglycaemia
    Insulin Resistance | Insulinoma | Hypoglycemia Unawareness | Hypoglycemia Non-Diabetic | Insulin Hypoglycemia | Hypoglycemia, Reactive | Hypoglycaemia Night | Insulinoma; Malignant, Pancreas | Spontaneous Hypoglycemia | Neuro Endocrine Tumours
    United Kingdom
  • Mayo Clinic
    National Cancer Institute (NCI)
    Active, not recruiting
    Nab-Paclitaxel and Bevacizumab in Treating Patients With Unresectable Stage IV Melanoma or Gynecological Cancers
    Malignant Solid Neoplasm | Ovarian Endometrioid Adenocarcinoma | Ovarian Undifferentiated Carcinoma | Cervical Adenocarcinoma | Cervical Adenosquamous Carcinoma | Malignant Peritoneal Neoplasm | Endometrial Clear Cell Adenocarcinoma | Endometrial Endometrioid Adenocarcinoma | Endometrial Mixed Cell... and other conditions
    United States
  • Institut National de la Santé Et de la Recherche...
    Gustave Roussy, Cancer Campus, Grand Paris; Ligue contre le cancer, France; Université...
    Active, not recruiting
    The French E3N Prospective Cohort Study (E3N)
    Depression | Cardiovascular Diseases | Melanoma | Hypertension | Diabetes | Breast Cancer | Parkinson Disease | Inflammatory Bowel Diseases | Asthma | Endometriosis | Crohn Disease | Endometrial Cancer | Colo-rectal Cancer | Thyroid Cancer
  • 858 Therapeutics, Inc.
    Recruiting
    A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies (ERADIC8)
    Breast Cancer | Gastric Cancer | Colorectal Cancer | Ovarian Cancer | Prostate Cancer | Endometrial Cancer | Epithelial Ovarian Cancer | BRCA1 Mutation | BRCA2 Mutation | Advanced or Metastatic Solid Tumors | ER+ Breast Cancer | Castrate Resistant Prostate Cancer | BRCA Mutation
    United States
  • Centre Hospitalier de Valence
    Not yet recruiting
    Evaluation of the Medical Service by Socio-aesthetics in Oncology (RCT-SE)
    Anxiety Depression | Cancer, Breast | Cancer Pain | Cancer of Colon | Cancer, Lung | Cancer Prostate
  • Charite University, Berlin, Germany
    Completed
    Evaluation of an Integrated Care Project (ediva)
    Depression | Migraine | Asthma | Allergic Rhinitis | Headache | Atopic Eczema
    Germany
  • Constellation Pharmaceuticals
    Recruiting
    A Study of CPI-0209 in Patients With Advanced Solid Tumors and Lymphomas
    Lymphoma, T-Cell | Mesothelioma, Malignant | Advanced Solid Tumor | Endometrial Cancer | Diffuse Large B Cell Lymphoma | Ovarian Clear Cell Carcinoma | Prostatic Neoplasms, Castration-Resistant
    United States, Korea, Republic of, France, United Kingdom, Italy, Spain, Poland
  • Novartis Pharmaceuticals
    Terminated
    A Phase 2 Study of NIR178 in Combination With PDR001 in Patients With Solid Tumors and Non-Hodgkin Lymphoma
    Melanoma | Head and Neck Cancer | Pancreatic Cancer | Urothelial Cancer | NSCLC, Non Small Cell Lung Cancer | RCC, Renal Cell Cancer | DLBCL, Diffused Large B Cell Lymphoma | MSS, Microsatellite Stable Colon Cancer | TNBC, Triple Negative Breast Cancer | mCRPC, Metastatic Castration Resistant Prostate...
    Belgium, Italy, Taiwan, Germany, Spain, United States, Argentina, Australia, Austria, Czechia, France, Japan, Netherlands, Switzerland, Singapore
  • Exelixis
    Recruiting
    Study of XB002 in Subjects With Solid Tumors (JEWEL-101)
    Cervical Cancer | Pancreatic Cancer | Non Small Cell Lung Cancer | Triple Negative Breast Cancer | Endometrial Cancer | Epithelial Ovarian Cancer | Metastatic Castration-resistant Prostate Cancer | Hormone Receptor-positive Breast Cancer | SCCHN | Esophageal SCC | Tissue Factor-Expressing Solid Tumors
    United States, Spain, Australia, Belgium, France, Italy, Netherlands, United Kingdom, Korea, Republic of
  • University of California, San Francisco
    National Institute on Aging (NIA)
    Completed
    Rural Dementia Caregiver Project
    Depression | Stress, Psychological | Dementia | Dementia, Vascular | Loneliness | Self Efficacy | Dementia, Mixed | Health Care Utilization | Dementia Alzheimers | Dementia of Alzheimer Type | Social Isolation | Dementia, Multi-Infarct | Dementia, Lewy Body | Dementia in Parkinsons Disease | Dementia Frontal | Dementia... and other conditions
    United States
  • National Center for Complementary and Integrative...
    Completed
    Women's Use of Alternative Medicine: A Multiethnic Study
    Depression | Arthritis | Urinary Tract Infection | Osteoporosis | Heart Disease | Uterine Fibroids | High Blood Pressure | Headaches
  • M.D. Anderson Cancer Center
    Janssen Pharmaceutica
    Active, not recruiting
    Cabazitaxel, Carboplatin, and Cetrelimab Followed by Niraparib With or Without Cetrelimab for the Treatment of Aggressive Variant Metastatic Prostate Cancer
    Castration-Resistant Prostate Carcinoma | Metastatic Prostate Carcinoma | Stage IV Prostate Cancer AJCC v8 | Aggressive Variant Prostate Carcinoma | Metastatic Prostate Neuroendocrine Carcinoma | Metastatic Prostate Small Cell Carcinoma
    United States
  • McMaster University
    Canadian Institutes of Health Research (CIHR)
    Recruiting
    Relative Impacts on Preventative Primary Care--a Longitudinal Evaluation of COVID-19:Phase 1 (RIPPLE-C)
    Diabetes Mellitus | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Osteoarthritis | Dementia | Congestive Heart Failure | Depression, Anxiety
    Canada
  • M.D. Anderson Cancer Center
    National Cancer Institute (NCI)
    Recruiting
    DS3201 and Ipilimumab for the Treatment of Metastatic Prostate, Urothelial and Renal Cell Cancers
    Metastatic Clear Cell Renal Cell Carcinoma | Castration-Resistant Prostate Carcinoma | Metastatic Prostate Carcinoma | Stage IV Prostate Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Metastatic Malignant Solid Neoplasm | Metastatic Urothelial Carcinoma | Stage IVA Prostate Cancer AJCC v8 | Stage... and other conditions
    United States
  • Rigshospitalet, Denmark
    Copenhagen University Hospital - Rigshospitalet, Department of Occupational... and other collaborators
    Recruiting
    The SaVe Project-Sarcopenia and Vertigo in Aging Patients With Colorectal Cancer (SaVe)
    Cancer | Colorectal Cancer | Chemotherapy | Exercise | Sarcopenia | Vertigo | Rehabilitation | Elderly | Older Adults | Resistance Training | Geriatric | Chemotherapy-induced Peripheral Neuropathy | Vestibular Rehabilitation | Oncologic Complications | Comprehensive Geriatric Assessment | Frail | Postural Stability | Balance... and other conditions
    Denmark
  • Future Genetics Limited
    Recruiting
    EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality
    Depression | Cardiovascular Diseases | Heart Failure | Epilepsy | Hypertension | Obesity | Diabetes Mellitus | Cancer | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Rheumatoid Arthritis | Peripheral Arterial Disease | Atrial Fibrillation | Asthma | Dementia | Blood Pressure | Coronary Heart Disease | Mental... and other conditions
    United Kingdom
  • National Cancer Institute (NCI)
    NRG Oncology
    Active, not recruiting
    Comparison of Standard of Care Treatment With a Triplet Combination of Targeted Immunotherapeutic Agents
    Ovarian Seromucinous Carcinoma | Recurrent Ovarian High Grade Serous Adenocarcinoma | Recurrent Platinum-Resistant Ovarian Carcinoma | Fallopian Tube Mucinous Adenocarcinoma | Recurrent Fallopian Tube Clear Cell Adenocarcinoma | Recurrent Fallopian Tube Endometrioid Adenocarcinoma | Recurrent... and other conditions
    United States, Puerto Rico
  • M.D. Anderson Cancer Center
    National Cancer Institute (NCI)
    Active, not recruiting
    Niraparib and Copanlisib in Treating Patients With Recurrent Endometrial, Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
    Progressive Disease | Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Endometrial Carcinoma | Endometrial Adenocarcinoma | Primary Peritoneal High Grade Serous Adenocarcinoma | Platinum-Resistant Ovarian Carcinoma | High Grade Ovarian... and other conditions
    United States
  • Willows Health
    Nottingham Trent University
    Not yet recruiting
    Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY) (BRANCH-P)
    Depression | Heart Diseases | Cardiovascular Diseases | HIV Infections | Obesity | Diabetes | Cancer | Chronic Kidney Diseases | Arthritis | Bulimia | Alzheimer Disease | Cellulitis | Cirrhosis | Eczema | Osteoporosis | Appendicitis | Bronchitis | Bowel Disease | Gout | Alcoholic Liver Disease | Flu | High Cholesterol | Allergies | Indigestion | ... and other conditions
    United Kingdom
  • University of Southern Denmark
    Zealand University Hospital; Holbaek Sygehus; Naestved Hospital; Nykøbing Falster... and other collaborators
    Active, not recruiting
    Personalized Exercise Therapy and Self-management Support for Patients With Multimorbidity (MOBILIZE)
    Depression | Heart Failure | Hypertension | Chronic Obstructive Pulmonary Disease | Osteoarthritis, Knee | Coronary Heart Disease | Osteoarthritis, Hip | Type2 Diabetes
    Denmark
  • University of Southern California
    National Institute on Aging (NIA); Huntington Hospital
    Completed
    Social Work Intervention Focused on Transitions (SWIFT)
    Depression | Stroke | Hypertension | Diabetes | Cancer | Chronic Obstructive Pulmonary Disease | Asthma | Chronic Heart Failure | Heart Disease | Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention
    United States
  • University of Missouri-Columbia
    National Library of Medicine (NLM)
    Completed
    Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow
    Depression | HIV Infections | Hypertension | Obesity | Diabetes Mellitus | Back Pain | Urinary Incontinence | Irritable Bowel Syndrome | Insomnia | Asthma | Anxiety | Sinusitis | Shoulder Pain | Allergic Rhinitis | Urinary Tract Infection | Vaginitis | Bursitis | Hyperlipidemia | Esophageal Reflux | Benign Prostatic Hypertrophy | Osteoporosis... and other conditions
    United States
  • Professor Adrian Covic
    Medical Sciences Academy - Romania; Victor Babes Clinical Hospital of Infectious...
    Unknown
    Integrated Distance Management Strategy for Patients With Cardiovascular Diseases in the Context of COVID-19 (eCardioCovid19)
    Coronary Artery Disease | Hypertension | Covid-19 | Angina Pectoris | Acute Coronary Syndrome | Heart Failure, Systolic | Depression, Anxiety | Coronary Syndrome | Stent Restenosis | Angioplasty | Isolation, Social
    Romania
  • Xencor, Inc.
    Recruiting
    Phase 1, First-in-human, Dose-finding and Expansion Study to Evaluate XmAb®808 in Combination With Pembrolizumab in Advanced Solid Tumors
    Colorectal Cancer | Castration-resistant Prostate Cancer | Head and Neck Squamous Cell Carcinoma | Urothelial Carcinoma | Ovarian Cancer, Epithelial | TNBC - Triple-Negative Breast Cancer | Renal Cell Carcinoma, Clear Cell | Melanoma Excluding Uveal Melanoma | Non-small Cell Lung Cancer, Squamous or...
    United States
  • SOTIO Biotech AG
    Merck Sharp & Dohme LLC
    Active, not recruiting
    A Study of SOT101 in Combination With Pembrolizumab to Evaluate the Efficacy and Safety in Patients With Selected Advanced Solid Tumors
    Hepatocellular Carcinoma | Colorectal Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Castration-resistant Prostate Cancer | Cutaneous Squamous Cell Carcinoma
    Italy, Spain, France, Belgium, Czechia, United States, Poland, Georgia, Hungary
  • Roswell Park Cancer Institute
    National Cancer Institute (NCI)
    Active, not recruiting
    Gene-Modified T Cells With or Without Decitabine in Treating Patients With Advanced Malignancies Expressing NY-ESO-1
    Metastatic Melanoma | Advanced Malignant Solid Neoplasm | Unresectable Melanoma | Clinical Stage III Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIB Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Pathologic Stage IIID Cutaneous Melanoma AJCC v8 | Pathologic Stage... and other conditions
    United States
  • University of Missouri-Columbia
    National Library of Medicine (NLM)
    Completed
    MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use
    Depression | Coronary Artery Disease | HIV Infections | Smoking Cessation | Hypertension | Obesity | Diabetes Mellitus | Chronic Obstructive Pulmonary Disease | Osteoarthritis | Hypothyroidism | Back Pain | Urinary Incontinence | Irritable Bowel Syndrome | Diarrhea | Migraine Disorders | Cough | Sleep Initiation and Maintenance... and other conditions
  • Roswell Park Cancer Institute
    National Cancer Institute (NCI); Merck Sharp & Dohme LLC; Celldex Therapeutics
    Recruiting
    Pembrolizumab Combined With Bevacizumab With or Without Agonist Anti-CD40 CDX-1140 for the Treatment of Patients With Recurrent Ovarian Cancer
    Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Endometrial Serous Adenocarcinoma | Ovarian Clear Cell Adenocarcinoma | Recurrent Platinum-Resistant Ovarian Carcinoma | Platinum-Sensitive Ovarian Carcinoma | Recurrent Fallopian... and other conditions
    United States
  • M.D. Anderson Cancer Center
    Bristol-Myers Squibb; National Cancer Institute (NCI); Iovance Biotherapeutics
    Active, not recruiting
    Autologous Tumor Infiltrating Lymphocytes MDA-TIL in Treating Patients With Recurrent or Refractory Ovarian Cancer, Colorectal Cancer, or Pancreatic Ductal Adenocarcinoma
    Malignant Solid Neoplasm | Metastatic Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Platinum-Resistant Ovarian Carcinoma | Metastatic Pancreatic Ductal Adenocarcinoma | Metastatic Ovarian Carcinoma and other conditions
    United States
  • Ohio State University Comprehensive Cancer Center
    National Cancer Institute (NCI)
    Completed
    Stress Reduction in Improving Quality of Life in Patients With Recurrent Gynecologic or Breast Cancer
    Depression | Pain | Fatigue | Pseudomyxoma Peritonei | Peritoneal Carcinomatosis | Recurrent Endometrial Carcinoma | Anxiety Disorder | Ovarian Sarcoma | Recurrent Uterine Sarcoma | Recurrent Breast Cancer | Leydig Cell Tumor | Recurrent Ovarian Epithelial Cancer | Recurrent Primary Peritoneal Cavity Cancer | Ovarian... and other conditions
    United States
  • University of Tennessee
    Sponsor GmbH
    Recruiting
    Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence (MedAAAction)
    Depression | Coronary Artery Disease | Stroke | Hypertension | Diabetes | Chronic Kidney Diseases | Anxiety | Chronic Lung Disease | Pulmonary Embolism | Congestive Heart Failure | Arrythmia | Heart Attack | High Cholesterol/Hyperlipidemia
    United States
  • Jonsson Comprehensive Cancer Center
    Blue Note Therapeutics
    Terminated
    Cognitive-Behavioral Stress Management Device for the Treatment of Anxiety and Depressive Symptoms in Patients With Stage I-III Breast or Lung Cancer (BNT001)
    Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions
    United States
  • Sanguine Biosciences
    Completed
    At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions
    Depression | Melanoma | Epilepsy | Lymphoma | Multiple Sclerosis | Kidney Cancer | Cervical Cancer | Diabetes Mellitus | Leukemia | Breast Cancer | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Parkinson's Disease | Systemic Lupus Erythematosus | Multiple Myeloma | Hepatitis B | Insomnia | Colorectal Cancer | HIV/AID... and other conditions
    United States
  • Nurix Therapeutics, Inc.
    Recruiting
    A Study of NX-1607 in Adults With Advanced Malignancies
    Cervical Cancer | Gastric Cancer | Head and Neck Squamous Cell Carcinoma | Non-small Cell Lung Cancer (NSCLC) | Metastatic Urothelial Carcinoma | Ovarian Cancer, Epithelial | Metastatic Castration-resistant Prostate Cancer (mCRPC) | Triple Negative Breast Cancer (TNBC) | Malignant Pleural Mesothelioma... and other conditions
    United States, United Kingdom
  • Wake Forest University Health Sciences
    National Cancer Institute (NCI); National Center for Complementary and Integrative...
    Completed
    Programs To Support You During Chemotherapy (PRO-YOU)
    Depression | Stomach Cancer | Fatigue | Pancreatic Cancer | Esophageal Cancer | Small Intestine Cancer | Anal Cancer | Liver Cancer | Biliary Tract Cancer | Gallbladder Cancer | Appendix Cancer | Stage IVA Colorectal Cancer | Stage IVB Colorectal Cancer | Stage IIIA Colorectal Cancer | Stage IIIB Colorectal Cancer | Stage... and other conditions
    United States
  • National Cancer Institute (NCI)
    Completed
    MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia
    Unspecified Childhood Solid Tumor, Protocol Specific | Chronic Myelomonocytic Leukemia | Juvenile Myelomonocytic Leukemia | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone... and other conditions
    United States, Canada
  • National Cancer Institute (NCI)
    Completed
    Alvocidib, Fludarabine Phosphate, and Rituximab in Treating Patients With Lymphoproliferative Disorders or Mantle Cell Lymphoma
    Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Splenic Marginal Zone Lymphoma | Waldenström Macroglobulinemia and other conditions
    United States
  • National Cancer Institute (NCI)
    Active, not recruiting
    Testing the PD-1 Antibody, MK3475, Given With Ziv-aflibercept in Patients With Advanced Cancer
    Sarcoma | Metastatic Renal Cell Carcinoma | Metastatic Melanoma | Recurrent Renal Cell Carcinoma | Recurrent Melanoma | Stage IV Renal Cell Cancer AJCC v8 | Metastatic Malignant Solid Neoplasm | Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Clinical Stage IV Cutaneous Melanoma... and other conditions
    United States, Canada
  • Actuate Therapeutics Inc.
    Active, not recruiting
    9-ING-41 in Patients With Advanced Cancers
    Sarcoma | Cancer | Breast Neoplasms | Neoplasm Metastasis | Pancreatic Neoplasms | Pancreatic Cancer | Pancreatic Adenocarcinoma | Bone Cancer | Malignant Glioma | Bone Metastases | Pancreas Cancer | Renal Cancer | Refractory Non-Hodgkin Lymphoma | Bone Neoplasm | Neoplasm, Breast | Refractory Cancer | Refractory Neoplasm | Resistant... and other conditions
    United States, Belgium, Canada, Spain, France, Netherlands, Portugal
  • City of Hope Medical Center
    National Cancer Institute (NCI)
    Withdrawn
    Diabetes Prevention Program (METFIT) in Reducing Insulin Resistance in Stage I-III Breast Cancer Survivors
    Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions
  • NiKang Therapeutics, Inc.
    Recruiting
    A Study With NKT3447 for Adults With Advanced/Metastatic Solid Tumors
    Small Cell Lung Carcinoma | Gastric Cancer | Ovarian Neoplasms | Ovarian Cancer | Solid Tumor | Endometrial Neoplasms | Triple Negative Breast Cancer | Triple Negative Breast Neoplasms | Advanced Solid Tumor | Endometrial Cancer | Small-cell Lung Cancer | Platinum-resistant Ovarian Cancer | Ovarian Carcinoma | Solid... and other conditions
    United States
  • M.D. Anderson Cancer Center
    National Cancer Institute (NCI); Iovance Biotherapeutics, Inc.
    Active, not recruiting
    LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas
    Malignant Solid Neoplasm | Soft Tissue Sarcoma | Recurrent Ovarian Carcinoma | Triple Negative Breast Cancer | Recurrent Osteosarcoma | Refractory Osteosarcoma | Bone Sarcoma | Giant Cell Tumor of Bone | Ovarian Carcinosarcoma | Platinum-Resistant Ovarian Carcinoma | Dedifferentiated Chondrosarcoma | Malignancy... and other conditions
    United States
  • UK Kidney Association
    Recruiting
    National Registry of Rare Kidney Diseases (RaDaR)
    Vasculitis | AL Amyloidosis | Tuberous Sclerosis | Fabry Disease | Cystinuria | Focal Segmental Glomerulosclerosis | IgA Nephropathy | Bartter Syndrome | Pure Red Cell Aplasia | Membranous Nephropathy | Atypical Hemolytic Uremic Syndrome | Autosomal Dominant Polycystic Kidney Disease | Cystinosis | Nephronophthisis | BK Nephropathy and other conditions
    United Kingdom
  • National Cancer Institute (NCI)
    Withdrawn
    Talazoparib in Treating Patients With Advanced or Metastatic Solid Tumors That Cannot Be Removed by Surgery and Liver or Kidney Dysfunction
    Stage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Stage IV Non-Small Cell Lung Cancer | Metastatic Pancreatic Adenocarcinoma | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast... and other conditions
  • National Cancer Institute (NCI)
    Terminated
    Sunitinib in Treating Patients With Idiopathic Myelofibrosis
    Primary Myelofibrosis | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult Acute Myeloid Leukemia... and other conditions
    United States
  • National Cancer Institute (NCI)
    Recruiting
    Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations
    Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Advanced Pancreatic Carcinoma | Metastatic Pancreatic Carcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Castration-Resistant Prostate Carcinoma and other conditions
    United States
  • OHSU Knight Cancer Institute
    Oregon Health and Science University
    Terminated
    Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial
    Primary Myelofibrosis | Anemia | Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Anatomic Stage IV Breast Cancer AJCC v8 | Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Chronic Myelomonocytic Leukemia | Refractory Myelodysplastic... and other conditions
    United States

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