Clinical Trials on Diabetes Mellitus, Atherosclerosis in United States

Total 9056 results

Clearside Biomedical, Inc.

Completed

Suprachoroidal CLS-TA With Intravitreal Aflibercept Versus Aflibercept Alone in Subject With Diabetic Macular Edema (TYBEE)

Diabetic Macular Edema

United States
Jaeb Center for Health Research
National Eye Institute (NEI); National Institutes of Health (NIH); Regeneron...

Completed

Treatment for CI-DME in Eyes With Very Good VA Study (Protocol V)

Diabetic Macular Edema

United States, Canada
Kyowa Kirin, Inc.

Recruiting

Study to Assess the Efficacy & Safety of KHK4951 in Patients With Diabetic Macular Edema

Diabetic Macular Edema (DME)

Australia, United States, Japan, Korea, Republic of
EyeBiotech Ltd.

Recruiting

A 2-part Study Consisting of Multiple Ascending Dose (MAD) Safety Study, and a Dose-finding Masked Study to Assess the Safety and Efficacy of Intravitreal (IVT) EYE103 in Patients With Diabetic Macular Edema (DME) or Neovascular Age-related Macular Degeneration (NVAMD) (AMARONE)

Diabetic Macular Edema (DME) | Neovascular Age-related Macular Degeneration (NVAMD)

United States, Argentina, Puerto Rico, United Kingdom
Pfizer's Upjohn has merged with Mylan to form Viatris...

Terminated

Examination of Pregabalin Access for Treatment of Indicated Pain Disorders: the ExPAND Study

Fibromyalgia | Painful Diabetic Peripheral Neuropathy

United States
ThromboGenics

Completed

A Multicenter Study to Compare Multiple Doses of Intravitreal Microplasmin Versus Sham Injection for Treatment of Patients With Diabetic Macular Edema (DME) (MIVI-II)

Diabetic Macular Edema

Spain, Belgium, United Kingdom, Italy, Netherlands, Germany
Rezolute

Active, not recruiting

Study to Evaluate the Efficacy and Safety of RZ402 in Diabetic Macular Edema (DME)

Diabetic Macular Edema

United States
Alimera Sciences

Active, not recruiting

A Study of Intravitreal ILUVIEN® Implant as Baseline Therapy in Patients With Early Diabetic Macular Edema (DME) (NEW DAY)

Diabetic Macular Edema

United States
Hoffmann-La Roche

Completed

A Study to Evaluate the Efficacy and Safety of Faricimab (RO6867461) in Participants With Diabetic Macular Edema (RHINE)

Diabetic Macular Edema

United States, Korea, Republic of, United Kingdom, Brazil, China, Canada, Argentina, Australia, Denmark, France, Italy, Poland, Spain, Germany, Singapore, Czechia, Hong Kong, Portugal, Russian Federation, Taiwan, Hungary, Switzerland and more
Lateral Pharma Pty Ltd

Completed

Oral LAT8881 in Neuropathic Pain

Neuropathic Pain | Diabetic Peripheral Neuropathy (DPN) | Post Herpetic Neuralgia (PHN)

Australia, United Kingdom
Hoffmann-La Roche

Completed

A Study to Evaluate the Efficacy and Safety of Faricimab (RO6867461) in Participants With Diabetic Macular Edema (YOSEMITE)

Diabetic Macular Edema

United States, Japan, Israel, Austria, France, Germany, Hungary, Italy, Mexico, Poland, Slovakia, Spain, Russian Federation, Bulgaria, Turkey, Peru
Sanguine Biosciences

Completed

At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions

Depression | Melanoma | Epilepsy | Lymphoma | Multiple Sclerosis | Kidney Cancer | Cervical Cancer | Diabetes Mellitus | Leukemia | Breast Cancer | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Parkinson's Disease | Systemic Lupus Erythematosus | Multiple Myeloma | Hepatitis B | Insomnia | Colorectal Cancer | HIV/AID... and other conditions

United States
CinDome Pharma, Inc.

Recruiting

A Study to Evaluate the Efficacy and Safety of CIN-102 (Deudomperidone) in Adults With Diabetic Gastroparesis

Diabetic Gastroparesis

United States
Hoffmann-La Roche

Completed

A Study to Evaluate the Long-Term Safety and Tolerability of Faricimab in Participants With Diabetic Macular Edema (Rhone-X)

Diabetic Macular Edema

United States, Korea, Republic of, United Kingdom, Brazil, Japan, Canada, Argentina, Australia, Austria, Denmark, France, Germany, Hungary, Italy, Poland, Slovakia, Spain, Singapore, Czechia, Hong Kong, Israel, Portugal, Russian Federation and more
Tranzyme, Inc.

Terminated

Diabetic Gastroparesis Efficacy/Safety Study of TZP-102 (DIGEST)

Diabetic Gastroparesis

United States, Poland
University of Leicester

Recruiting

Usability and Acceptability Study of the P-STEP Mobile Application

Heart Failure | Chronic Obstructive Pulmonary Disease | Asthma | Type 2 Diabetes | Coronary Heart Disease | Interstitial Lung Disease

United Kingdom
Neurogastrx, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of NG101 in Adult Participants With Symptomatic Diabetic or Idiopathic Gastroparesis

Diabetic Gastroparesis | Idiopathic Gastroparesis

United States
Rigshospitalet, Denmark
University College, London

Enrolling by invitation

EuroSIDA - Clinical and Virological Outcome of European Patients Infected With HIV (EuroSIDA)

End Stage Liver Disease | Cardiovascular Diseases | Fractures, Bone | Diabetes Mellitus | Renal Insufficiency | Hepatitis B | Hepatitis C | Kidney Failure, Chronic | Proteinuria | HIV | Coinfection | Acidosis, Lactic | AIDS

Spain, Switzerland, Germany, United Kingdom, Austria, Sweden, Finland, Israel, Denmark, France, Italy, Iceland, Belgium, Slovakia, Norway, Lithuania, Portugal, Poland, Croatia, Czechia, Greece, Hungary, Luxembourg, Argentina, Belarus, Bosnia... and more
UK Kidney Association

Recruiting

National Registry of Rare Kidney Diseases (RaDaR)

Vasculitis | AL Amyloidosis | Tuberous Sclerosis | Fabry Disease | Cystinuria | Focal Segmental Glomerulosclerosis | IgA Nephropathy | Bartter Syndrome | Pure Red Cell Aplasia | Membranous Nephropathy | Atypical Hemolytic Uremic Syndrome | Autosomal Dominant Polycystic Kidney Disease | Cystinosis | Nephronophthisis | BK Nephropathy and other conditions

United Kingdom
Regeneron Pharmaceuticals
Bayer

Completed

Study of Intravitreal Aflibercept Injection (IAI; EYLEA®; BAY86-5321) in Patients With Diabetic Macular Edema (VISTA DME)

Diabetic Macular Edema

United States
Khondrion BV
Julius Clinical; ProPharma Group; Certara

Completed

The KHENEREXT Study

Mitochondrial Diseases | Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation | Maternally Inherited Diabetes and Deafness (MIDD) | Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke Like Episodes (MELAS) | Chronic Progressive External Ophthalmoplegia (CPEO)

Netherlands, Denmark, United Kingdom, Germany
AstraZeneca

Completed

European Study of Cardiovascular Risk (EURIKA)

Smoking | Hypertension | Obesity | Diabetes | Hyperlipidemia | Cardiovascular Risk Factors

Sweden, France, Russian Federation, Spain, Turkey, United Kingdom, Germany, Norway, Austria, Belgium, Switzerland, Greece
Novartis

Completed

A 12 Month Core Study to Assess the Efficacy and Safety of Ranibizumab (Intravitreal Injections) in Patients With Visual Impairment Due to Diabetic Macular Edema and a 24 Month Open-label Extension Study (RESTORE)

Diabetic Macular Edema

Greece, Belgium, Spain, France, Netherlands, Australia, Canada, Germany, Hungary, Italy, Switzerland, Turkey, United Kingdom
Eli Lilly and Company

Recruiting

A Study of LY3556050 in Adult Participants With Diabetic Peripheral Neuropathic Pain

Diabetic Peripheral Neuropathy

United States, Korea, Republic of, Japan, Czechia, Poland
Millennium Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Efficacy and Safety of TAK-906 in Adult Participants With Symptomatic Idiopathic or Diabetic Gastroparesis

Diabetic Gastroparesis | Idiopathic Gastroparesis

United States, Belgium, Japan, Poland
Evoke Pharma

Completed

Multicenter Study to Evaluate the Efficacy and Safety of Metoclopramide Nasal Spray in Men With Diabetic Gastroparesis

Diabetic Gastroparesis

United States
Sanguine Biosciences

Recruiting

Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives

Heart Diseases | Stroke | Lymphoma | Multiple Sclerosis | Kidney Diseases | Diabetes | Leukemia | Age-Related Macular Degeneration | Cancer | Arthritis | Schizophrenia | Thyroid Diseases | Parkinson Disease | Hepatitis | Vasculitis | Psoriasis | Asthma | Amyloidosis | Fibromyalgia | Graves Disease | Alzheimer Disease | Celiac Disease | Cirr... and other conditions

United States
Hoffmann-La Roche

Recruiting

A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products (VOYAGER)

Diabetic Macular Edema | Neovascular Age-related Macular Degeneration

Spain, Germany, Croatia, Israel, Japan, United Kingdom, United States, Italy, Switzerland, France, Canada, Australia, Singapore, Puerto Rico, United Arab Emirates, Bulgaria, Chile, Czechia
Bayer

Recruiting

The SPECTRUM Study: An Observational Study to Learn More About How Well Aflibercept 8 mg Works in Treating Visual Impairment Due to Neovascular Age-related Macular Degeneration or Diabetic Macula Edema

Visual Impairment | Neovascular Age-related Macular Degeneration (nAMD) | Diabetic Macula Edema (DME)

Germany, Canada, Denmark, France, Italy, Saudi Arabia, Switzerland, Australia, Finland, Netherlands, Sweden, Norway, United Arab Emirates, Japan, United Kingdom
Pfizer

Terminated

A Phase 2, Multi-Center Study To Compare The Efficacy And Safety Of A Chemokine CCR2/5 Receptor Antagonist With Ranibizumab In Adults With Diabetic Macular Edema

Macular Edema, Diabetic

United States, Israel, Germany, Hungary, Bulgaria, Czech Republic, Moldova, Republic of, Poland, Romania
Macrocure Ltd.
ICON plc; Amarex Clinical Research; ARANZ Medical

Completed

Evaluation of CureXcell® in Treating Lower Extremity Chronic Ulcers in Adults With Diabetes

Lower Extremity Chronic Ulcers in Diabetics

United States, Israel, Canada
University College, London

Unknown

The Role of Alcohol Consumption in the Aetiology of Different Cardiovascular Disease Phenotypes: a CALIBER Study

Heart Failure | Mortality | Peripheral Arterial Disease | Cardiac Arrest | Ventricular Arrhythmias | Acute Myocardial Infarction | Unstable Angina | Sudden Cardiac Death | Abdominal Aortic Aneurysm | Chronic Stable Angina | Coronary Heart Disease (CHD) | Non-ST Elevation Myocardial Infarction (nSTEMI) | ST Elevation... and other conditions

United Kingdom
Organogenesis
Continuum Clinical Inc.

Completed

The RESPOND Registry (RESPOND)

Surgical Wounds | Pressure Ulcer | Venous Ulcer | Partial Thickness Wound | Diabetic Ulcer | Trauma Wounds | Draining Wounds | Chronic Vascular Ulcer

United States
Royal Marsden NHS Foundation Trust
Imperial College London; Institute of Cancer Research, United Kingdom; RM Partners...

Recruiting

The Man Van Project (MV)

Smoking | Alcoholism | Urologic Diseases | Hypertension | Diabetes | Prostate Cancer | Bladder Cancer | Renal Cancer | Urologic Cancer | Mental Health Issue | Testis Cancer

United Kingdom
SerenaGroup, Inc.
Kinetic Concepts, Inc.

Terminated

Clinical Trial to Evaluate Blister Graft Utilizing a Novel Harvesting Device for Treatment of Venous Leg Ulcers (Cellutome)

Venous Insufficiency of Leg | Impaired Wound Healing | Diabetic Ulcers

United States
Chelsea Therapeutics
Chiltern International Inc.

Completed

A Clinical Study for Patients With Neurogenic Orthostatic Hypotension (NOH) Using Droxidopa (NOH301)

Primary Autonomic Failure | Dopamine Beta Hydroxylase Deficiency | Symptomatic Neurogenic Orthostatic Hypotension (NOH) | Non-diabetic Neuropathy

United States, Canada
Otsuka Pharmaceutical Development & Commercialization...

Completed

A PK Study of 3 Dosages of Tolvaptan in Patients With Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

Germany, United Kingdom, Spain, Sweden, Hungary, Czech Republic, Denmark
Yale University
National Institute of Neurological Disorders and Stroke (NINDS); Takeda Pharmaceuticals...

Completed

Insulin Resistance Intervention After Stroke Trial (IRIS)

Myocardial Infarction | Stroke | Diabetes

United States, Germany, Israel, Australia, United Kingdom, Canada, Italy, Puerto Rico
Kodiak Sciences Inc

Terminated

A Trial to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Participants With Diabetic Macular Edema (DME) (GLEAM)

Diabetic Macular Edema

United States, Latvia, Spain, Germany, Italy, Slovakia, Hungary, Puerto Rico
Kodiak Sciences Inc

Terminated

A Study to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Participants With Diabetic Macular Edema (DME) (GLIMMER)

Diabetic Macular Edema

United States, Israel, France, Italy, Hungary, Poland, Puerto Rico, Czechia
Mathematica Policy Research, Inc.
Centers for Medicare and Medicaid Services

Unknown

Evaluation of Programs of Coordinated Care and Disease Management (Coca)

Coronary Artery Disease | Diabetes | Cancer | Chronic Obstructive Pulmonary Disease | Major Depression | Alzheimer's Disease | Congestive Heart Failure | Cerebrovascular Disease | Psychotic Disorder

United States
Outlook Therapeutics, Inc.

Completed

A 3-month Study to Assess the Safety of ONS-5010 in Subjects With Visual Impairment Due to Retinal Disorders

Age-related Macular Degeneration | Diabetic Macular Edema | Wet Macular Degeneration | Neovascular Age-related Macular Degeneration | BRVO - Branch Retinal Vein Occlusion

United States
Novartis Pharmaceuticals

Completed

Observe the Effectiveness and Safety of Ranibizumab in Real Life Setting (LUMINOUS)

Diabetic Macular Edema | Retinal Vein Occlusion | Wet Age Related Macular Degeneration | Wet Age Related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion

Spain, China, Colombia, Korea, Republic of, Belgium, Greece, Japan, Russian Federation, Turkey, United Kingdom, Egypt, Germany, Australia, Canada, France, Austria, Hong Kong, Hungary, Israel, Netherlands, Peru, Singapore, Slovakia, Sl... and more
Barts & The London NHS Trust

Terminated

CGM (Continuous Glucose Monitoring) Use in Diagnosis of Spontaneous and Reactive Hypoglycaemia

Insulin Resistance | Insulinoma | Hypoglycemia Unawareness | Hypoglycemia Non-Diabetic | Insulin Hypoglycemia | Hypoglycemia, Reactive | Hypoglycaemia Night | Insulinoma; Malignant, Pancreas | Spontaneous Hypoglycemia | Neuro Endocrine Tumours

United Kingdom
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Brolucizumab vs. Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (KESTREL)

Diabetic Macular Edema

United States, Austria, Japan, Australia, Spain, Canada, Israel, Netherlands, Italy, United Kingdom, Portugal, Colombia, Puerto Rico, Argentina
Eli Lilly and Company

Recruiting

A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain (CPMP)

Chronic Low-back Pain | Osteoarthritis, Knee | Diabetic Neuropathic Pain

United States, Puerto Rico
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Brolucizumab vs Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (KINGFISHER)

Diabetic Macular Edema

United States, Hungary, Israel, Slovakia, Puerto Rico
Newcastle University
Assistance Publique - Hôpitaux de Paris; Medical University of Vienna; University... and other collaborators

Recruiting

The European NAFLD Registry

Cardiovascular Diseases | Hypertension | Obesity | Hepatocellular Carcinoma | Type 2 Diabetes | NAFLD | Fibrosis, Liver | NASH - Nonalcoholic Steatohepatitis | Dyslipidaemia | NASH | Steatosis of Liver | Other Associated Comorbidities

Netherlands, Germany, United Kingdom, Finland, Belgium, Greece, Italy, Sweden, Portugal, Spain, France, Switzerland
Sanford Health
National Ataxia Foundation; Beyond Batten Disease Foundation; Pitt Hopkins Research... and other collaborators

Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (CoRDS)

Mitochondrial Diseases | Retinitis Pigmentosa | Myasthenia Gravis | Eosinophilic Gastroenteritis | Multiple System Atrophy | Leiomyosarcoma | Leukodystrophy | Anal Fistula | Spinocerebellar Ataxia Type 3 | Friedreich Ataxia | Kennedy Disease | Lyme Disease | Hemophagocytic Lymphohistiocytosis | Spinocerebellar Ataxia... and other conditions

United States, Australia
Chelsea Therapeutics
Chiltern International Inc.

Completed

Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH) (NOH302)

Primary Autonomic Failure | Dopamine Beta Hydroxylase Deficiency | Symptomatic Neurogenic Orthostatic Hypotension (NOH) | Non-diabetic Neuropathy

United States, Australia, Canada, New Zealand

Clinical Trials on Diabetes Mellitus, Atherosclerosis in United States

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