Clinical Trials on Digestive System Abnormalities

Total 206108 results

Columbia University
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

CT for Personalized Mechanical Ventilation

Ventilator-Induced Lung Injury | Sepsis Syndrome | Mechanical Ventilation Complication

United States
University of Pennsylvania

Withdrawn

Oritavancin for Staphylococcus Aureus Infections in Opioid Users

Staphylococcus Aureus Bacteremia | Staphylococcus Aureus Endocarditis

United States
Institute of Tropical Medicine, Belgium
Institut National de Recherche Biomédicale. Kinshasa, République Démocratique... and other collaborators

Completed

IDIS Project Work Package 2: Establishing a Biobank at ITM and Collaborating Centres (IDIS)

Fever | Salmonella Infections | Blood Stream Infections | Salmonella Septicemia | Parasitic Infections

Belgium, Cambodia, Congo, The Democratic Republic of the
Beaumont Hospital

Unknown

Randomised Controlled Trial of Needle Free Access Devices in Preventing Hemodialysis Blood Stream Infection (TEGO)

Central Line Infection | Hemodialysis Catheter Blood Stream Infection | Dialysis Line Thrombosis

Ireland
Heidelberg University
Gilead Sciences

Unknown

Diagnostic Study of Combined Biomnarker Testing in Bronchoalveolar Lavage Samples of Immunocompromised Patients

Stem Cell Transplantation | Biomarkers | Acute Leukemia | Invasive Aspergillosis

Germany
Emory University
Dana-Farber Cancer Institute; University of Massachusetts, Worcester

Completed

Mindfulness Meditation in Bone Marrow Transplantation

Stem Cell Transplantation | Bone Marrow Transplantation | Hematologic Malignancy

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Withdrawn

Botanical Therapy in Treating Mucositis in Patients With Head and Neck Cancer Who Have Undergone Chemoradiation Therapy

Mucositis | Tongue Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous Cell Carcinoma of the Oropharynx | Recurrent Squamous Cell Carcinoma of the Paranasal... and other conditions
Assistance Publique - Hôpitaux de Paris

Recruiting

Vaginal Self-sampling for Detecting High-risk Human Papillomavirus Cervical Infection in Patients With Immune-mediated Inflammatory Diseases (APOSY)

HPV Infection | Systemic Disease

France
Università degli Studi di Ferrara
University of Milan

Not yet recruiting

Evaluation of Regional Ventilation Distribution in Patients Affected by Abdominal Sepsis After Emergent Laparotomy (CHESTOMY)

Emergencies | Acute Respiratory Failure | Ventilation Therapy; Complications | Abdominal Sepsis

Italy
Centre Hospitalier Universitaire, Amiens

Recruiting

Prognostic Value Serum Concentration of Indoxyl Sulfate During Acute Kidney Injury in Septic Shock Patients. (TOX-AKI)

Mortality | Septic Shock | Acute Kidney Injury | Uremic; Toxemia

France
Massachusetts General Hospital

Completed

Cholecalciferol Supplementation for Sepsis in the ICU (CSI)

Hypovitaminosis D

United States
Canadian Critical Care Trials Group
The Physicians' Services Incorporated Foundation

Completed

Pilot Study of the Utility of Empiric Antibiotic Therapy for Suspected ICU-Acquired Infection

Pneumonia | Systemic Inflammatory Response Syndrome | Critical Illness | Nosocomial Infection | Pyrexia

Canada
City of Hope Medical Center

Terminated

Deferasirox for Treating Patients Who Have Undergone Allogeneic Stem Cell Transplant and Have Iron Overload

Primary Myelofibrosis | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Iron Overload | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell... and other conditions

United States
Hospices Civils de Lyon

Recruiting

Monitoring of Measles-specific Immune Status in Adult Allogeneic Hematopoietic Stem Cell Transplant Recipients (MaRROwVacc)

Transplantation, Hematopoietic Stem Cell

France
First Affiliated Hospital of Zhejiang University
Second Affiliated Hospital, School of Medicine, Zhejiang University; Sir Run... and other collaborators

Recruiting

Venetoclax Combining With Fludarabine and Melphalan as Conditioning Regimen for Allo-HSCT

Allogeneic Hematopoietic Stem Cell Transplantation | Hematologic Malignancy | Older Patients

China
University Hospital, Lille

Recruiting

Impact of Supportive Care on the Experience of Hospitalization of Patients Staying in the Protected Area of the Department of Blood Diseases (ASTERIA)

Acute Leukemia | Aplasia | Hematopoietic Stem Cell Transplantation (SCT)

France
Omeros Corporation
Impatients N.V. trading as myTomorrows

Available

Single Patient Expanded Access Treatment Plan For The Investigational Product Narsoplimab

Hematopoietic Stem Cell Transplant Associated Thrombotic Microangiopathy (HSCT-TMA)
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Alemtuzumab, Fludarabine Phosphate, and Low-Dose Total Body Irradiation Before Donor Stem Cell Transplantation in Treating Patients With Hematological Malignancies

Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent... and other conditions

United States, Italy
Roswell Park Cancer Institute

Withdrawn

Mechanical Stimulation in Preventing Bone Density Loss in Patients Undergoing Donor Stem Cell Transplant

Primary Myelofibrosis | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma and other conditions
Rumah Sakit Pusat Angkatan Darat Gatot Soebroto
Indonesia University

Completed

The Effect of Intralesian Injection of Umbilical Cord Mesenchymal Stem Cells, Its Conditioned Medium, and Triamcinolone Acetonide on Type 1:3 Collagen Ratio and Interleukin-10 Levels in Keloid: A Randomised Controlled Trial

Keloid | Stem Cell

Indonesia
Rumah Sakit Pusat Angkatan Darat Gatot Soebroto
Indonesia University

Completed

Comparison of Keloid Volume and Symptoms Reduction Between Intralesional Umbilical-Cord Mesenchymal Stem Cells, Its Conditioned Medium, and Triamcinolone Acetonide Injection as Keloid Therapy: A Randomised Controlled Trial

Keloid | Stem Cell

Indonesia
Joshua M Hare
National Heart, Lung, and Blood Institute (NHLBI); The Emmes Company, LLC; Johns...

Terminated

Prospective Randomized Study of Mesenchymal Stem Cell Therapy in Patients Undergoing Cardiac Surgery (PROMETHEUS) (PROMETHEUS)

Stem Cell Transplantation | Ventricular Dysfunction, Left

United States
Children's Hospital Medical Center, Cincinnati

Completed

Bortezomib to Treat Significant Complication of HSCT (Bortezomib)

Allogeneic Stem Cell Transplantation | Refractory Autoimmune Cytopenia(s)

United States
Capital Medical University

Not yet recruiting

Discover the Immune Signature of Sepsis Caused by Acute Pulmonary Infection: A Cohort Study (DISPLAY)

Sepsis | Influenza | Upper Respiratory Tract Infection | Viral Pneumonia

China
Inonu University

Completed

NGAL and Renal Resistive Index in the Diagnosis and Prognosis of Sepsis-associated AKI (NGAL)

Sepsis | Acute Kidney Injury

Turkey
Fundacion para la Formacion e Investigacion Sanitarias...

Completed

Defibrotide as Prevention and Treatment of Respiratory Distress and Cytokine Release Syndrome of Covid 19. (DEFACOVID)

COVID19

Spain
University Hospital Hradec Kralove

Completed

Circulatory Coherence in COVID-19 and Non-COVID-19 Patients With Sepsis

Sepsis | Viral Pneumonia

Czechia
CorMedix
PPD; Davita Clinical Research; JMI Laboratories; Spectra Clinical Research; Frenova...

Completed

Study Assessing Safety & Effectiveness of a Catheter Lock Solution in Dialysis Patients to Prevent Bloodstream Infection

Kidney Failure, Chronic | Catheter-Related Infections

United States
University of Florida
American Society of Nephrology

Withdrawn

Severe Sepsis in Children - IMPRESS-C (IMPRESS-C)

Hypertension | Chronic Kidney Disease | Acute Kidney Injury

United States
The Cleveland Clinic

Withdrawn

Thiamine Supplementation in Patients With Septic Shock

Septic Shock | Shock, Septic | Lactic Acidosis | Thiamine Deficiency

United States
Second Affiliated Hospital of Soochow University

Recruiting

Clinical Application of Quantitative Ultrasonographic Analysis in Early Kidney Injury

Patient Admitted to Hospital With Acute Kidney Injury Due to Sepsis

China
University College, London
King's College London; Rambam Health Care Campus; University of Melbourne; Menzies... and other collaborators

Not yet recruiting

18-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in S. Aureus Bacteraemia (PET-SAB)

Sepsis | Staphylococcus Aureus Infection | Bloodstream Infection | Staphylococcus Aureus Bacteremia | Sepsis Bacterial | Staphylococcus Aureus Septicemia | Staph Sepsis
FMH College of Medicine and Dentistry

Completed

TOCILIZUMAB - An Option for Patients With COVID-19 Associated Cytokine Release Syndrome; A Single Center Experience

Covid19

Pakistan
University Hospital, Lille
Ministry of Health, France

Terminated

Preventing Catheter-related Bacteremia When Administering Injectable Medications in Premature Infants. (MultilineNEO)

Bacteremia | Infant, Very Low Birth Weight

France
Zhongda Hospital

Unknown

Renal Resistive Index and Cardiac Output Changes During Resuscitation Predict the Occurrence of Acute Kidney Injury in Septic Shock Patients (CORRI)

Septic Shock | Acute Kidney Injury | Critically Ill

China
Second Affiliated Hospital of Guangzhou Medical...

Recruiting

ExtraCorporeal Membrane Oxygenation in the Therapy for REfractory Septic Shock With Cardiac Function Under Estimated (ECMO-RESCUE)

Septic Shock | Extracorporeal Membrane Oxygenation | Cardiogenic Shock | Septic Cardiomyopathy

China
Johns Hopkins University
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Cardiac Assessment by PV Loop in IPAH and Scleroderma PAH (CALIPSO)

Pulmonary Artery Hypertension | Scleroderma

United States
Michigan State University

Recruiting

Clinical Microbial Species & Antibiotic Resistance ID in ED Patients Presenting With Infection - is Rapid ID Possible & Accurate?

Sepsis | Systemic Inflammatory Response Syndrome | Infection, Bacterial | Infection, Coronavirus | Infection, Fungal | Infection Mixed

United States
ContraFect

Terminated

Direct Lysis of Staph Aureus Resistant Pathogen Trial of Exebacase (DISRUPT)

Staphylococcus Aureus Bacteremia | Staphylococcus Aureus Endocarditis

United States
Hamad Medical Corporation

Completed

Switch to Oral Antibiotics in Gram-negative Bacteremia (SOAB)

Escherichia Coli Bacteremia | Klebsiella Bacteraemia | Enterobacter Bacteraemia | Serratia Bacteraemia | Citrobacter Bacteraemia | Proteus Bacteraemia

Qatar, Turkey, Bahrain, Kuwait
Louisiana State University Health Sciences Center...
Parsemus Foundation

Completed

Use of a Live Attenuated Vaccine as an Immune-based Preventive Against COVID-19-associated Sepsis

Sepsis Syndrome

United States
University of Alabama at Birmingham
Merck Sharp & Dohme LLC

Completed

Antibiotic Prophlaxis for High-risk Laboring Women in Low Income Countries

Postpartum Sepsis | Postpartum Endometritis | Postpartum Fever

Cameroon
Noveome Biotherapeutics, formerly Stemnion
IQVIA Biotech

Completed

Safety and Tolerability Study of IV ST266 in COVID-19 Subjects

Cytokine Release Syndrome

United States
Vanderbilt University Medical Center
Baxter Healthcare Corporation

Terminated

Peripheral Venous Analysis (PIVA) for Predicting Volume Responsiveness and Fluid Status (PIVA)

Systemic Inflammatory Response Syndrome | Atrial Fibrillation | Hypotension and Shock | Distributive Shock | Decompensated Congestive Heart Failure | High Risk Non-cardiac Surgery

United States
Institute of Tropical Medicine, Belgium
World Health Organization; Institut National de Recherche Biomédicale. Kinshasa... and other collaborators

Terminated

Piloting Clinical Bacteriology in the Ebola Virus Disease Care Response (Bact_EVD)

Ebola Virus Disease | Bloodstream Infection | Sepsis Bacterial

Congo, The Democratic Republic of the
Michael Roth
National Heart, Lung, and Blood Institute (NHLBI); Hoffmann-La Roche

Completed

Comparison of Therapeutic Regimens for Scleroderma Interstitial Lung Disease (The Scleroderma Lung Study II) (SLSII)

Interstitial Lung Disease | Scleroderma

United States
Abramson Cancer Center at Penn Medicine
Medtronic

Active, not recruiting

Long Term Arrhythmia Risk and Cardiovascular Events in Hematopoietic Stem Cell Transplant (ARCHER)

Atrial Fibrillation | Atrial Flutter | Hematopoietic Stem Cell Transplant

United States
National Heart, Lung, and Blood Institute (NHLBI)
National Institutes of Health Clinical Center (CC)

Recruiting

Early Detection of Infectious and Noninfectious Lung Diseases Following Allogeneic Hematopoietic Stem Cell Transplantation

Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)

United States
University Hospital, Limoges

Recruiting

AntiCMV molécules Monitoring in Real-life in Stem Cell Recipients (NAViRe)

Cytomegalovirus Infections | Hematopoietic Stem Cell Transplantation | Antivirals | Antiviral Drug Resistance

France
Guangzhou Women and Children's Medical Center

Completed

Mesenchymal Stem Cells for the Treatment of Pneumonia Post Haematopoietic Stem Cell Transplantation (MSCTPHSCT)

Pneumonia | Hematopoietic Stem Cell Transplantation

China

Clinical Trials on Digestive System Abnormalities

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