Search clinical trials for: tumor-specific TCR-T cells

Total 2173 results

Sun Yat-sen University

Unknown

Phase I Trial of LMP2 Antigen-specific TCR T-cell Therapy for Recurrent and Metastatic NPC Patients

Nasopharyngeal Carcinoma

China
Xinqiao Hospital of Chongqing
TCRCure Biopharma Ltd.

Unknown

HPV-E6-Specific Anti-PD1 TCR-T Cells in the Treatment of HPV-Positive NHSCC or Cervical Cancer

Cervical Cancer | Head and Neck Squamous Cell Carcinoma

China
Baylor College of Medicine
Cancer Prevention Research Institute of Texas; The Methodist Hospital Research... and other collaborators

Recruiting

Administration of Donor Multi TAA-Specific T Cells for AML or MDS (ADSPAM)

Acute Myeloid Leukemia | Myelodysplastic Syndrome

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Active, not recruiting

Administration of Donor MultiTAA-Specific T Cells for ALL (STELLA)

Leukemia, Lymphoblastic (Acute)

United States
JIANG LONGWEI
Nanjing University

Recruiting

A Study of Tumor Neoantigen-specific T Cells in the Treatment of Advanced Solid Tumors (Neoantigen-T)

Tumor, Solid

China
Children's National Research Institute

Recruiting

Multi Tumor-Associated Antigen-Specific T Lymphocytes to Treat Patients With High Risk Solid Tumors

Solid Tumor

United States
Sun Yat-sen University
Guangdong Xiangxue Precision Medical Technology Co., Ltd.

Recruiting

Phase II Study of TAEST16001 in Soft Tissue Sarcoma

Soft Tissue Sarcoma

China
Guangzhou FineImmune Biotechnology Co., LTD.
Sun Yat-sen University

Recruiting

Individualized Tumor Specific TCR- T Cells in the Treatment of Advanced Solid Tumors

Solid Tumor

China
Xinqiao Hospital of Chongqing
TCRCure Biopharma Ltd.

Recruiting

EBV-Specific Anti-PD1 TCR-T Cells in the Treatment of EBV-Positive NHSCC

Head and Neck Squamous Cell Carcinoma

China
Mariella Enoc

Completed

Trial to Assess the Efficacy of a TCR Alfa Beta Depleted Graft in Pediatric Affected by ALL or AML and Receiving an HSCT

Myelodysplastic Syndromes | Acute Lymphoblastic Leukemia | Non-Hodgkin Lymphoma | Leukemia Acute Myeloid - AML

Italy
Zhujiang Hospital
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University; Shenzhen Geno-Immune...

Recruiting

CAR-T Cells Combined With Peptide Specific Dendritic Cell in Relapsed/Refractory Leukemia/MDS

Myelodysplastic Syndromes | Leukemia, Acute Myelogenous (AML) | Leukemia, Acute Lymphocytic (ALL)

China
Second Affiliated Hospital of Guangzhou Medical...
Tcell Immune (Guangzhou) Science and Technology Ltd.

Recruiting

TCR-T Cell Immunotherapy of Lung Cancer and Other Solid Tumors

Nonsmall Cell Lung Cancer | Solid Tumor, Adult

China
Beijing Geekgene Technology Co., LTD

Recruiting

a Single-arm, Single-center, Open Clinical Study (GK-01)

Cervical Cancer | Gastric Cancer | Esophageal Cancer | Non-Small Cell Lung Cancer NSCLC | Triple Negative Breast Cancer TNBC

China
Alaunos Therapeutics

Active, not recruiting

Long-Term Follow-up Study of Subjects Treated With Autologous T Cells Using the Sleeping Beauty System to Express TCRs

Gynecologic Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Cholangiocarcinoma | Adenocarcinoma of Lung | Non-small Cell Lung Cancer | Squamous Cell Lung Cancer | Ovary Neoplasm | Adenosquamous Cell Lung Cancer

United States
Chinese PLA General Hospital

Recruiting

Clinical Study of EBV-TCR-T Cells for EBV-associated Hemophagocytic Lymphohistiocytosis or EBV Infection

EBV Infection | EBV-associated Hemophagocytic Lymphohistiocytosis

China
Xiao-Jun Huang

Recruiting

CMV-TCR-T Cells for Refractory CMV Infection After HSCT

Allogeneic Hematopoietic Stem Cell Transplantation | CMV Infection

China
Beijing 302 Hospital
Lion TCR Pte. Ltd.

Recruiting

TCR-Redirected T Cells Therapy in Patient With HBV Related HCC

Hepatocellular Carcinoma

China
Hebei Yanda Ludaopei Hospital
China Immunotech (Beijing) Biotechnology Co., Ltd.

Completed

CMV-TCR-T Cells for CM Virus Infection After HSCT

CMV Infection or Reactivation After Allogenic HSCT

China
Chinese PLA General Hospital

Recruiting

Clinical Study of EBV-TCR-T Cells for EBV Infection After Allogenic HSCT

EBV Infection After Allogenic HSCT

China
Chinese PLA General Hospital

Recruiting

CMV-TCR-T Cells for CMV Infection After Allogenic HSCT

CMV Infection After Allogenic HSCT

China
Hebei Yanda Ludaopei Hospital
China Immunotech (Beijing) Biotechnology Co., Ltd.

Completed

EBV-TCR-T Cells for EB Virus Infection After HSCT

EBV Emia and EBV Positive PTLD After Allogenic HSCT

China
Cellular Biomedicine Group Ltd.
Shanghai Zhongshan Hospital

Unknown

AFP Specific T Cell Receptor Transduced T Cells Injection(C-TCR055) in Unresectable Hepatocellular Carcinoma

Hepatocellular Carcinoma

China
AlloVir
Baylor College of Medicine; The Methodist Hospital Research Institute; Center...

Completed

ARMS - Rapidly Generated Multivirus-Specific CTLs for Prophylaxis & Treatment of EBV, CMV, Adenovirus, HHV6 & BK Virus (ARMS)

Viral Infection

United States
Children's Hospital Medical Center, Cincinnati
Hoxworth Blood Center

Recruiting

Trial of Scheduled Versus Treatment Administration of Donor-Derived Viral Specific T-cells for Viral Infections After Stem Cell Transplant

Viral Infection | Allogeneic Stell Cell Transplant

United States
Lion TCR Pte. Ltd.

Recruiting

Redirected HBV-Specific T Cells in Patients With HBV-related HCC (SAFE-T-HBV) (SAFE-T-HBV)

Hepatocellular Carcinoma

Singapore
Ruijin Hospital
Shanghai Essight Bio Co.,Ltd

Recruiting

TCR-T Cells in the Treatment of Advanced Pancreatic Cancer (GB3010-02)

Pancreatic Cancer

China
Cell Medica Ltd
University College, London; Cell Therapy Catapult

Completed

WT1 TCR Gene Therapy for Leukaemia: A Phase I/II Safety and Toxicity Study

Acute Myeloid Leukaemia | Chronic Myeloid Leukaemia

United Kingdom
Christian Hinrichs
National Cancer Institute (NCI)

Not yet recruiting

E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers

Cervical Cancer | HPV-Related Malignancy | Vulvar Cancer | Anal Cancer | Oropharynx Cancer | Vaginal Cancer | HPV-Related Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma | Penile Cancer | HPV-Associated Cervical Carcinoma | HPV-Related Adenocarcinoma | HPV-Related Adenosquamous Carcinoma | HPV-Related... and other conditions

United States
Peking University
Shanghai Ming Ju Biotechnology Co., Ltd.

Recruiting

MAGE-A4-directed TCR-T in the Treatment Amongst Subjects With Advanced Solid Tumors

Advanced Solid Tumor

China
Fudan University
Guangzhou Bioresette Biomedical Technology Co., Ltd.; Chaosu Hu，Principal Investigator...

Recruiting

Clinical Study on the EBV CAR-T /TCR-T Cells in the Treatment of Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

China
Xinqiao Hospital of Chongqing
TCRCure Biopharma Ltd.

Recruiting

EBV Specific Cytokine Secreting TCR-T Cells in the Treatment of EBV-Positive Metastatic/Refractory Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

China
Memorial Sloan Kettering Cancer Center

Withdrawn

Safety and Effectiveness of EBV-specific Cytotoxic T Cells for the Treatment for EBV Lymphomas or Other EBV-associated Malignancies

EBV Lymphomas | EBV-associated Malignancies
Peking University People's Hospital

Not yet recruiting

Multivirus-specific T Cells in the Treatment of Refractory CMV and/or EBV Infection After Allo-HSCT

Stem Cell Transplant | CMV Infection | EBV Infection
Istituto Giannina Gaslini

Not yet recruiting

Adoptive T-cell Therapy for Resistant Viral Infections After Allogeneic HSCT (VS-TC)

Viral Infection After HSCT
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Completed

Most Closely HLA-Matched CTLs for Relapsed Epstein Barr Virus(EBV)-Associated Diseases (MALTED)

Nasopharyngeal Carcinoma | Hodgkin Lymphoma | Non-Hodgkin Lymphoma | Leiomyosarcoma | Lymphoproliferative Disorder | Severe Chronic Active EBV (SCAEBV)

United States
Memorial Sloan Kettering Cancer Center

Recruiting

Trial of Third Party Donor Derived CMVpp65 Specific T-cells for The Treatment of CMV Infection or Persistent CMV Viremia After Allogeneic Hematopoietic Stem Cell Transplantation

CMV Infection | Persistent CMV Viremia

United States
Baylor College of Medicine
Harris County Hospital District; The Methodist Hospital Research Institute; Center... and other collaborators

Active, not recruiting

TAA Specific Cytotoxic T Lymphocytes in Patients With Pancreatic Cancer (TACTOPS)

Pancreatic Cancer

United States
AlloVir
Baylor College of Medicine; The Methodist Hospital Research Institute; Center...

Completed

Multivirus-specific T Cells for the Treatment of Virus Infections After Stem Cell Transplant (CHARMS)

Infection

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Completed

Giving Epstein-Barr Virus (EBV) Specific Killer T Lymphocytes to Patients Who Have Had Donor Marrow Grafts (ETNA)

Epstein-Barr Virus Infections

United States
Seattle Children's Hospital
The Evan Foundation; Ben Towne Center for Childhood Cancer Research

Active, not recruiting

Engineered Neuroblastoma Cellular Immunotherapy (ENCIT)-01

Neuroblastoma | Ganglioneuroblastoma

United States
University College, London

Suspended

Study of Adoptive Immunotherapy With Donor-derived CMV-specific T Cells for Recipients of Allo-HSCT (CMV_TCR-001)

CMV Infection | Haematological Malignancies

United Kingdom
Tianjin Medical University Cancer Institute and...

Unknown

Clinical Safety and Preliminary Efficacy of MAGE-A4 TCR Gene-Modified T Cells to Treat Malignant Tumors

Malignant Solid Tumors

China
The Netherlands Cancer Institute

Unknown

Study With T-cel Receptor Gene Therapy in Metastatic Melanoma (TCR)

Stage IV Skin Melanoma | Eye; Melanoma

Netherlands
Sun Yat-sen University
Guangdong Xiangxue Precision Medical Technology Co., Ltd.

Active, not recruiting

NY-ESO-1-specific T Cell Receptor (TCR) T Cell in Sarcoma

Soft Tissue Sarcoma | Bone Sarcoma

China
Baylor College of Medicine
National Cancer Institute (NCI); National Institutes of Health (NIH); The Methodist... and other collaborators

Recruiting

Cytotoxic T-Lymphocytes for EBV-positive Lymphoma, GRALE (GRALE)

Lymphoma | Non-Hodgkin's Lymphoma | Hodgkin's Disease | Lymphoproliferative Disease

United States
Children's National Research Institute

Active, not recruiting

Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT) (IMPACT)

Medulloblastoma, Childhood | Embryonal Tumor With Multilayered Rosettes | Pineoblastoma | Embryonal Tumor of CNS | Atypical Teratoid/Rhabdoid Tumor of CNS

United States
Children's Hospital Medical Center, Cincinnati
Hoxworth Blood Center

Active, not recruiting

Viral Specific T-cells for Treatment of Viral Infections After Solid Organ Transplant

Solid Organ Transplant | Viral Infection

United States
Children's Hospital Medical Center, Cincinnati
Hoxworth Blood Center

Withdrawn

Viral Specific T-cells for Treatment of COVID-19

Viral Infection

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Completed

Safety, Toxicity and MTD of One Intravenous IV Injection of Donor CTLs Specific for CMV and Adenovirus (ACT-CAT)

Cytomegalovirus Infection | Adenovirus Infection

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Completed

Administration of Rapidly Generated Multivirus-specific Cytotoxic T-Lymphocytes (VIRAGE)

Epstein-Barr Virus Infections | Stem Cell Transplant | Cytomegalovirus Infections | Adenovirus Infection

United States

Search clinical trials for: tumor-specific TCR-T cells

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