Clinical Trials on Disease Progression

Total 382282 results

Eli Lilly and Company
Boehringer Ingelheim

Completed

Open Label Phase III Duloxetine Study for Stress Urinary Incontinence

Urinary Incontinence Stress

United Kingdom
Jonsson Comprehensive Cancer Center
Novartis; Seagen Inc.

Recruiting

Ribociclib, Tucatinib, and Trastuzumab for the Treatment of HER2 Positive Breast Cancer

Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC... and other conditions

United States
Jonsson Comprehensive Cancer Center
Breast Cancer Research Foundation; MetVital, Inc.

Recruiting

Oxaloacetate for the Improvement of Cognitive Complaints in Stage 0-IIIA Breast Cancer Survivors

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Prognostic... and other conditions

United States
OHSU Knight Cancer Institute
Eli Lilly and Company; GlaxoSmithKline; Oregon Health and Science University

Active, not recruiting

Abemaciclib and Niraparib Before Surgery for the Treatment of Hormone Receptor Positive HER2 Negative Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Prognostic... and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Rifaximin for the Treatment of Gastrointestinal Toxicities Related to Pertuzumab-Based Therapy in Patients With Stage I-III HER2 Positive Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions

United States
M.D. Anderson Cancer Center

Active, not recruiting

Exercise During Chemotherapy in Older Women With Stage I-III Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions

United States
Roswell Park Cancer Institute
National Center for Advancing Translational Sciences (NCATS)

Completed

Chemokine Modulation Therapy and Standard Chemotherapy Before Surgery for the Treatment of Early Stage Triple Negative Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Prognostic Stage I Breast Cancer AJCC v8 | Prognostic... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Geriatric and Quality of Life Assessments in Older Patients With Non-metastatic or Metastatic Head and Neck or Lung Cancer Undergoing Surgery or Chemoradiation and Their Caregivers

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage III Lung Cancer AJCC v8 | Metastatic Lung Carcinoma | Stage IV Lung Cancer AJCC v8 | Head and Neck Carcinoma | Lung Carcinoma | Stage II Lung Cancer AJCC v8 | Stage IIA Lung Cancer AJCC v8 | Stage IIB Lung Cancer AJCC v8 | Stage IIIA Lung... and other conditions

United States
Ohio State University Comprehensive Cancer Center

Recruiting

Health Coaching-Based Navigation at the Conclusion of Treatment for the Support of Black Breast Cancer Survivors

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions

United States
University of Alabama at Birmingham
National Cancer Institute (NCI)

Recruiting

A Quality of Life Intervention (Y-AMBIENT) for Young African American With Stage I-III Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions

United States
Thomas Jefferson University
National Cancer Institute (NCI)

Active, not recruiting

A Text-based Intervention in Improving Adherence to Hormone Therapy in Patients With Stage I-III Hormone Receptor Positive Breast Cancer

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 and other conditions

United States
William Carson

Active, not recruiting

Prospective Pilot Study of Robot-assisted Nipple Sparing Mastectomy (RNSM)

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Prognostic... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Mirvetuximab Soravtansine as First Line in Treating Patients With Triple Negative Breast Cancer

Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC... and other conditions

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biomarkers in Bone Marrow Samples From Pediatric Patients With High-Risk Acute Myeloid Leukemia

Childhood Acute Erythroleukemia (M6) | Childhood Acute Megakaryocytic Leukemia (M7) | Childhood Acute Monoblastic Leukemia (M5a) | Childhood Acute Monocytic Leukemia (M5b) | Childhood Acute Myeloblastic Leukemia With Maturation (M2) | Childhood Acute Myeloblastic Leukemia Without Maturation... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

A Pilot Study to Evaluate the Co-Infusion of Ex Vivo Expanded Cord Blood Cells With an Unmanipulated Cord Blood Unit in Patients Undergoing Cord Blood Transplant for Hematologic Malignancies

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Immunoblastic Large Cell Lymphoma and other conditions

United States
Bubba Nicholson
Tampa General Hospital; Otrimed Clinical Research

Unknown

Healthy Adult Male Facial Skin Surface Lipid Pheromone p.o. to Treat Opioid Addiction

Opioid-Related Disorders | Opioid Dependence | Opioid Use | Opioid Abuse | Opioid-use Disorder | Opioid Addiction | Opioid Intoxication | Opioid Abuse, Continuous Use | Paternal Pheromone Deficiency | Opioid Abuse, Episodic
M.D. Anderson Cancer Center

Recruiting

Pembrolizumab and Lenvatinib for the Treatment of Advanced, Unresectable, or Metastatic Gastroesophageal Adenocarcinoma

Clinical Stage III Gastric Cancer AJCC v8 | Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage IV Gastric Cancer AJCC v8 | Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction... and other conditions

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Recruiting

Ramucirumab and Trifluridine/Tipiracil or Paclitaxel for the Treatment of Patients With Previously Treated Advanced Gastric or Gastroesophageal Junction Cancer

Clinical Stage III Gastric Cancer AJCC v8 | Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage IV Gastric Cancer AJCC v8 | Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction... and other conditions

United States
Medical University of South Carolina
United States Department of Defense; Institute for Translational Neuroscience

Completed

NAC for Treating Comorbid PTSD and SUD (DoD-NAC)

Alcohol Use Disorder (AUD) | Posttraumatic Stress Disorder (PTSD) | Substance Use Disorder (SUD)

United States
Medical Research Council Cognition and Brain Sciences...
Cambridgeshire and Peterborough NHS Foundation Trust

Completed

The Modular Protocol for Mental Health (MPMH) (MPMH)

Obsessive-Compulsive Disorder | Generalized Anxiety Disorder | Major Depressive Disorder | Posttraumatic Stress Disorder | Social Anxiety Disorder | Panic Disorder | Agoraphobia | Illness Anxiety Disorder

United Kingdom
University of Washington
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institute... and other collaborators

Completed

A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity Pilot (TSOS6)

Substance-Related Disorders | Depression | Alcohol-Related Disorders | Quality of Life | Suicidal Ideation | Mild Cognitive Impairment | Posttraumatic Stress Disorder
Värmland County Council, Sweden
Uppsala University; Uppsala County Council, Sweden

Not yet recruiting

Sleep in Children With Autism and Intellectual Disability (SLEEP-AID IT)

Insomnia | Intellectual Disability | Autism
Moscow Psychiatric Hospital No. 1 Named after N...

Recruiting

Personalized Prospective Study Evaluation of the Efficacy and Safety of Noninvasive Neuromodulation of TMS in Subjects With Catatonia (RECATA)

Schizophrenia | Schizo Affective Disorder | Catatonia | Bipolar Affective Disorder

Russian Federation
Örebro University, Sweden
Uppsala University; Linkoeping University; Swedish Council for Working Life and... and other collaborators

Recruiting

Evaluation of a Home-based Parenting Support Program: Parenting Young Children (PYC)

Intellectual Disability | Autism Spectrum Disorder | Attention Deficit Hyperactivity Disorder

Sweden
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Surgery for Male Stress Urinary Incontinence (SMUI)

Male Stress Urinary Incontinence

Italy
Clinica Universidad de Navarra, Universidad de...

Recruiting

Staging Endometrial caNcer Based on molEcular ClAssification

Endometrial Cancer | Sentinel Lymph Node | Lymph Node Metastasis

Spain
Gangnam Severance Hospital

Recruiting

Performance of EEG During Emergence Agitation in Nasal Surgery.

Nasal Surgery

Korea, Republic of
Second Affiliated Hospital of Nanchang University
Yichang Humanwell Pharmaceutical Co., Ltd., China

Not yet recruiting

Effect of Rematazolam Besylate, Propofol, and Sevoflurane Perioperative Sedation on Incidence of Emergence Agitation and Hemodynamics in Patients Undergoing Laparoscopic Abdominal Surgery

Anesthesia, General | Emergence Agitation | Laparoscopic Abdominal Surgery | Remimazolam Besylate | Perioperative Sedation

China
Nanfang Hospital of Southern Medical University

Recruiting

Efficacy and Safety of Neoadjuvant Pembrolizumab in III-IVA Resectable Oral Squamous Cell Carcinoma (PROBES)

Oral Cavity Squamous Cell Carcinoma

China
University of Calgary
University of Chicago; Columbia University; University of Wisconsin, Madison; University... and other collaborators

Recruiting

Postoperative Return to Sexual Activity (PoRS)

Pelvic Organ Prolapse | Surgery | Stress Urinary Incontinence | Sexual Function Disturbances

Canada
Far Eastern Memorial Hospital

Recruiting

Efficacy of Biofeedback-Assisted Pelvic Muscle Floor Training and Electrical Stimulation on Women With Stress Urinary Incontinence

Stress Urinary Incontinence | Urethral Hypermobility | Intrinsic Sphincter Deficiency

Taiwan
Shanghai Jiao Tong University School of Medicine

Recruiting

Neoadjuvant Anti-PD-1 and TP Versus TPF on Pathological Response in OSCC

Chemotherapy | Oral Squamous Cell Carcinoma | Anti-PD-1 | Neoadjvant Therapy

China
Beijing Immunochina Medical Science & Technology...

Not yet recruiting

Safety and Efficacy of Chimeric Antigen Receptor T Lymphocytes for Patients With Intermediate and Advanced Tumors

Melanoma | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma

China
RPCR, Inc.
CyberKnife Coalition

Recruiting

Accelerated Partial Breast Irradiation (APBI) Using Stereotactic Body Radiation Therapy (SBRT)

Ductal Carcinoma in Situ | Invasive Ductal Carcinoma of Female Breast

United States
University Hospital Olomouc
Palacky University

Recruiting

Effect of Beta-alanine and Pelvic Floor Muscle Training on Urinary Incontinence After Radical Prostatectomy (BELA) (BELA)

Urinary Incontinence | Prostate Cancer | Radical Prostatectomy | Pelvic Floor Muscle Training | Beta-Alanine

Czechia
Assiut University

Not yet recruiting

Role of Piwi-protein Interacting RNA, miRNA-194 and Amino Acids in Patients With Prostate Cancer

Finding New Biomarkers That Could be Evaluated in Patients With Prostate Cancer and Clarify Their Role in Early Detection of Prostate Cancer

Egypt
UNICANCER

Recruiting

Study Comparing Fibula Free-flap MR With or Without PVP in Patients With OOPC (CURVE)

Oropharynx Squamous Cell Carcinoma | Oral Cavity Squamous Cell Carcinoma

France
Tianjin Medical University General Hospital

Recruiting

S-ketamine Prevents Postoperative Pain and Cognitive Dysfunction After Tibial Fracture

Postoperative Pain | Postoperative Cognitive Dysfunction

China
Direction Centrale du Service de Santé des Armées

Recruiting

Assessment of Sleep Disturbance as a Biomarker of Disease Activity in a Military Population With Posttraumatic Stress Disorder (SOMMEPT)

Post-traumatic Stress Disorder

France
AO Innovation Translation Center

Recruiting

Registry to Collect Data on Patients Undergoing Segmental Mandibular Defect Reconstruction Following Oral Squamous Cell Carcinoma Resection

Mandibular Reconstruction | Segmental Mandibular Defects

Germany, Switzerland, United States, Netherlands, Sweden, Spain
Mayo Clinic
National Cancer Institute (NCI); National Institute of Neurological Disorders...

Recruiting

Feasibility of Intraoperative Microdialysis During Neurosurgery for Central Nervous System Malignancies

Glioblastoma | Anaplastic Astrocytoma | Oligodendroglioma | Diffuse Astrocytoma | Anaplastic Oligodendroglioma | Metastatic Malignant Neoplasm in the Brain | Diffuse Glioma

United States
Lawson Health Research Institute

Recruiting

Preservation of Swallowing in Respected Oral Cavity Squamous Cell Carcinoma: Examining Radiation Volume Effects (PRESERVE): A Randomized Trial

Head and Neck Cancer

Canada, United States, Ireland, United Kingdom
Stanford University

Recruiting

Building a Platform for Precision Anesthesia in the Geriatric Surgical Patient

Cognitive Impairment | Cognitive Change | Postoperative Delirium | Cognitive Decline | Anesthesia; Reaction | Anesthesia; Adverse Effect

United States
Memorial Sloan Kettering Cancer Center

Recruiting

A Dye for the Detection of Cancer of the Tongue and Mouth

Oral Squamous Cell Carcinoma (OSCC)

United States
University of Sydney

Completed

Sleep Disturbance in MCI: A Study of a Cognitive Behavioural Therapy Digital Intervention (SUCCEED)

Sleep Wake Disorders | Insomnia | Cognitive Dysfunction | Mild Cognitive Impairment | Cognitive Disorder

Australia
National Cancer Institute (NCI)

Active, not recruiting

Cisplatin and Gemcitabine Hydrochloride With or Without Berzosertib in Treating Patients With Metastatic Urothelial Cancer

Metastatic Bladder Urothelial Carcinoma | Metastatic Ureter Urothelial Carcinoma | Stage IV Bladder Urothelial Carcinoma AJCC v7 | Metastatic Renal Pelvis and Ureter Urothelial Carcinoma

United States
Supernus Pharmaceuticals, Inc.

Terminated

Treatment of Impulsive Aggression in Subjects With ADHD in Conjunction With Standard ADHD Treatment (CHIME 4)

Attention Deficit Hyperactivity Disorder (ADHD)

United States
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Memantine for the Reduction of Cognitive Impairment After Radiation Therapy in Pediatric Patients With Central Nervous System Tumors

Malignant Central Nervous System Neoplasm | Primary Central Nervous System Neoplasm

United States
Hospital for Special Surgery, New York

Completed

Aromatherapy in Total Knee Replacement

Depression | Anxiety | Opioid Use | Post Operative Pain | Total Knee Replacement | Post-operative Nausea and Vomiting

United States
National Institute of Mental Health, Dhaka
Sun Pharmaceutical Industries Limited

Completed

Efficacy of Mirtazapine in Major Depressive Disorder With Insomnia

Major Depressive Disorder With Insomnia

Bangladesh

Clinical Trials on Disease Progression

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