Clinical Trials on Disease or Lesions of the Anus, Rectum, or Distal Colon

Total 832 results

Federation Francophone de Cancerologie Digestive

Completed

Radiochemotherapy With Panitumumab in the Localised Epidermoid Carcinoma of the Anus

Epidermoid Carcinoma | Anus

France
Groupe Hospitalier Paris Saint Joseph

Completed

Tumor Recurrence After Abdominal-perineal Amputation in Squamous Cell Carcinoma of the Anus (RTA)

Squamous Cell Carcinoma of the Anal Canal

France
University Hospital, Grenoble

Completed

Mercuri Analysis Contribution on Handicap Evaluation in ArthrogypOsis, a Congenital Neuromuscular Disease (MACHAON)

Diagnosis of Arthrogryposis Amyoplasia or Distal Arthrogryposis | 5 Day Multidisciplinary Evaluation in AMC Clinic of the National Reference Center | With Physical Medecin, Medical Genetic and Imaging Departments at the Hospital Grenoble Alpes

France
University of Chicago
National Cancer Institute (NCI)

Completed

Genotype-guided Dosing of mFOLFIRINOX Chemotherapy in Patients With Previously Untreated Advanced Gastrointestinal Malignancies

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Acinar Cell Adenocarcinoma of the Pancreas | Duct Cell Adenocarcinoma of the Pancreas | Stage III Pancreatic Cancer | Stage IV Pancreatic... and other conditions

United States
US Oncology Research
Bayer Healthcare Pharmaceuticals, Inc./Bayer Schering Pharma

Terminated

Study of Colorectal Cancer Patients (Stage IIIC) With Either Regorafenib or Standard of Care (No Treatment) After Adjuvant FOLFOX

Colorectal Neoplasms | Adenocarcinoma of the Rectum | Adenocarcinoma of the Colon

United States
Antiva Biosciences

Terminated

Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection

HIV Infection | Anal Cancer | Human Papilloma Virus Infection | HSIL, High-Grade Squamous Intraepithelial Lesions | Anus Neoplasm

United States, Australia
Odense University Hospital
Sygehus Lillebaelt; Svendborg Hospital; Hospital of South West Jutland

Completed

The Value of Laparoscopic Ultrasound in Patients Undergoing Laparoscopic Resection for Cancer of the Colon or Rectum

Colon Cancer | Liver Metastases | Rectum Cancer

Denmark
Bordeaux Colorectal Institute Academy

Recruiting

Low Stable Pressure Pneumoperitoneum in Colorectal Surgery (CROSS STUDY) (CROSS)

Colorectal Surgery | Benign or Malignant Rectal or Colon Tumors

France, Switzerland, Argentina, Belgium, Germany, Italy, Netherlands, Spain, United Kingdom
Memorial Sloan Kettering Cancer Center

Recruiting

Biopsy After Radioembolization to Identify Changes in Tumor Cells From the Radiation

Colorectal Cancer | Colon Cancer | Liver Metastasis Colon Cancer | Adenocarcinoma of the Rectum | Colon Cancer Liver Metastasis | Adenocarcinoma of the Colon

United States
AbbVie (prior sponsor, Abbott)
Genentech, Inc.

Completed

Phase 2 Study of ABT-869 in Combination With mFOLFOX6 Versus Bevacizumab in Combination With mFOLFOX6 to Treat Advanced Colorectal Cancer

Advanced Colorectal Cancer | Adenocarcinoma of the Rectum | Adenocarcinoma of the Colon

United States, Australia, Belgium, Brazil, Canada, Czech Republic, Greece, Korea, Republic of, New Zealand, Poland, Portugal, Romania, Russian Federation, Spain
Shattuck Labs, Inc.

Completed

SL-279252 (PD1-Fc-OX40L) in Subjects With Advanced Solid Tumors or Lymphomas

Melanoma | Renal Cell Carcinoma | Hodgkin Lymphoma | Gastric Adenocarcinoma | Non Small Cell Lung Cancer | Squamous Cell Carcinoma of the Head and Neck | Diffuse Large B Cell Lymphoma | Urothelial Carcinoma | Gastroesophageal Junction Adenocarcinoma | Squamous Cell Carcinoma of the Skin | Squamous Cell Carcinoma... and other conditions

United States, Canada, Belgium, Spain
University of Kansas Medical Center

Not yet recruiting

Opioid-Free Pain Treatment in Trauma Patients

Femoral Neck Fractures | Distal Radius Fractures | Femoral Shaft Fracture | Intertrochanteric Fractures | Patella Fracture | Lisfranc Injuries | Distal Femur Fracture | Calcaneus Fractures | Clavicle Fractures | Proximal Humerus Fractures | Tibial Shaft Fracture With or Without Associated Fibula Fracture | Ankle... and other conditions

United States
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Dose Escalation Trial of Endoluminal High-Dose-Rate Brachytherapy With Concurrent Chemotherapy for Rectal or Anal Cancer in Patients With Recurrent Disease or Undergoing Non-Operative Management

Rectal or Anal Cancer

United States
Assistance Publique - Hôpitaux de Paris

Unknown

Human Intestinal Microbiome and Surgical Outcomes in Patients Undergoing Colorectal Cancer Surgery (Microbiota)

Adenocarcinoma of the Rectum | Adenocarcinoma of the Colon

France
Medical College of Wisconsin
M.D. Anderson Cancer Center; National Cancer Institute (NCI); The University... and other collaborators

Completed

The Prevent Anal Cancer Palpation Study

Anal Cancer

United States
Centre Hospitalier Universitaire Dijon

Terminated

Viewpoints on the Social Representations and Rationale Concerning the Choices of Patients, Doctors and Caregivers With Regard to the Management of Patients With Non-resectable Metastatic Cancer of the Colon, Stomach, Bile Ducts, Rectum, Pancreas or Lung, or Gastrointestinal Neuroendocrine Tumours (EOLE)

Non-resectable Metastatic Cancer of the Lung | Non-resectable Metastatic Cancer of the Colon | Non-resectable Metastatic Cancer of the Rectosigmoid Junction | Non-resectable Metastatic Cancer of the Stomach | Non-resectable Metastatic Cancer of the Bile Duct | Non-resectable Metastatic Cancer... and other conditions

France
Royal Marsden NHS Foundation Trust
Cancer Research UK; European Organisation for Research and Treatment of Cancer... and other collaborators

Unknown

International Multicentre Study in Advanced Anal Cancer Comparing Cisplatin Plus 5 FU vs Carboplatin Plus Weekly Paclitaxel (InterAACT)

Squamous Cell Carcinoma of the Anus

United States, Australia, United Kingdom
University of Sao Paulo
Santander

Terminated

Ear Acupuncture Effectiveness In Reducing The Signs And Symptoms Of Stress And Anxiety (EAEIRTSOSAA)

Inclusion Criteria: | Voluntary Participation in the Study With Available Time for Submission to the Sessions, Which Occur Over Two Months. | Have a Score of Stress Medium, High or Very High in the LSS Questionnaire, Completion of the STAI and General Form. | Exclusion Criteria: | Pregnant...
Intuitive Surgical

Active, not recruiting

da Vinci SP® Investigational Device Exemption Study in Colorectal Procedures

Colorectal Cancer | Benign or Malignant Rectal or Colon Tumors

United States, Korea, Republic of
Bordeaux Colorectal Institute Academy

Recruiting

Laparoscopic Colorectal Surgery Using Low-pressure Combined With Warm and Humidified Carbon Dioxide Insufflation (PAROS3)

Colorectal Surgery | Benign or Malignant Rectal or Colon Tumors

France
Case Comprehensive Cancer Center

Recruiting

The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors

Adenocarcinoma of the Rectum | Adenocarcinoma of the Colon | Stage III Colorectal Cancer | Stage I Colorectal Cancer | Stage II Colorectal Cancer

United States
Antiva Biosciences

Completed

Study of Topical ABI-1968 in Subjects With Precancerous Anal Lesions Resulting From Human Papillomavirus (HPV) Infection

HIV Infection | Anal Cancer | Anus Neoplasms | Human Papilloma Virus Infection | HSIL, High-Grade Squamous Intraepithelial Lesions

United States, Australia
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of California, San Francisco; University... and other collaborators

Active, not recruiting

Treatment in Preventing Anal Cancer in Patients With HIV and Anal High-Grade Lesions (ANCHOR)

HIV Infection | Anal Cancer | Human Papilloma Virus Infection | High-grade Squamous Intraepithelial Lesion

United States, Puerto Rico
Jagiellonian University

Completed

TREM-1 - a New Marker of Serious Infectious Complications in Colorectal Surgery?

Colorectal (Colon or Rectal) Cancer

Poland
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Completed

Avelumab in First-Line Maintenance Gastric Cancer (JAVELIN Gastric 100)

Unresectable, Locally Advanced or Metastatic, Adenocarcinoma of the Stomach, or of the Gastro Esophageal Junction

United States, Spain, Italy, Australia, Russian Federation, Taiwan, Korea, Republic of, Thailand, Canada, Turkey, Germany, Romania, United Kingdom, Hungary, Brazil, France, Japan
Association Sud pour la Recherche en Oncogériatrie

Completed

MOST: Mediterranean Oncology Senior Tests (MOST)

Colon Cancer Patients Receiving Chemotherapy in the Adjuvant or Metastatic Setting | Aged 70 or Older

France
University of Ljubljana
Novartis; Izola General Hospital; University Medical Centre Ljubljana; General... and other collaborators

Completed

Artificial Intelligence in Predicting Progression in Multiple Sclerosis Study (AI ProMiS)

Multiple Sclerosis | Multiple Sclerosis Lesion | Multiple Sclerosis Brain Lesion

Slovenia
Hospital Universitario Infanta Leonor

Recruiting

Mild Ankle Sprain Treatment: Functional Bandaging vs. no Immobilization (PED_HUIL0124)

Primary Disease or Condition Being Studied in the Trial or the Focus of the Study Mild Ankle Sprain

Spain
Centre Hospitalier Universitaire Dijon

Terminated

Comparison of Systematic Surgery Versus Surveillance and Rescue Surgery in Operable Oesophageal Cancer With a Complete Clinical Response to Radiochemotherapy (Esostrate)

Epidermoid Carcinoma or | Adenocarcinoma of the Thoracic Oesophagus or | Adenocarcinoma of the Oesogastric Junction (Siewert Type I or II) | Stage cT2 N1-3 M0 or cT3-T4a N0 or N1-3 M0

France
Hospital St. Joseph, Marseille, France

Unknown

Assessment of Cholangio-pancreatoscopy for the Diagnosis and the Treatment of Biliary and Pancreatic Diseases

Biliary Tract Diseases | Common Bile Duct Diseases | Pancreatic Duct Disorder | Lesions of Biliary or Wirsung Ducts

France
Universidad Católica San Antonio de Murcia
Universidad de Almeria

Active, not recruiting

Xiaxi Program for Back Health

Adults | No Sagittal Spine Disposition Disorder | No Surgery on the Spine or the Hamstring | No Specific Treatment for Spinal Pathology | Not Involved in Structured Exercise Programs Before or During the Time of the Study

Spain
OSI Pharmaceuticals

Completed

A Study of OSI-7904L Versus 5-FU/LV as Treatment in Patients With Biliary Tract Cancer

Locally Advanced or Metastatic Adenoca of the Biliary Tract

United States, Belgium, Germany, Poland, Romania, Switzerland
Travera Inc
xCures

Recruiting

Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx) (TraveraRTGx)

Melanoma | Carcinoma, Renal Cell | Carcinoma | Carcinoma, Non-Small-Cell Lung | Carcinoma, Hepatocellular | Carcinoma, Pancreatic | Pancreatic Cancer | Mesothelioma | Cholangiocarcinoma | Carcinoma, Neuroendocrine | Carcinoma, Small Cell | Pleural Effusion, Malignant | Carcinoma, Pancreatic Ductal | Carcinoma of the... and other conditions

United States
N.M.B. Medical Applications Ltd

Unknown

Study of NMB (Company's Name) Drug Ejecting Balloon for Arteriovenous Fistulae

Obstructive Lesions of Arteriovenous Dialysis Fistulae

Israel
N.M.B. Medical Applications Ltd

Unknown

Study of NMB Drug Ejecting Balloon for Arteriovenous Fistulae

Obstructive Lesions of Arteriovenous Dialysis Fistulae

Israel
Arthrex, Inc.

Recruiting

Registry of Arthrex Hand and Wrist Products

Ulnar/Radial Collateral Ligament Reconstruction | Ligament Repair or Reconstruction | Small Bone Fragments and Arthrodesis | Scapholunate Ligament Reconstruction | Carpal Fusion (Arthrodesis) of the Hand | Digital Tendon Transfers | Carpometacarpal Joint Arthroplasty

United States
Centre Hospitalier Universitaire Dijon

Not yet recruiting

Investigate the Efficacy of Chemotherapy in Patients With Positive ctDNA After Surgery and Adjuvant Chemotherapy for a Stage III Colorectal Cancer (CIRCULATE PAC)

Colon or Upper Rectum Adenocarcinoma

France
Region Skane

Recruiting

Comparison Between Blocks or Not in Joint Arthroplasty (BLAST)

Osteoarthritis of the Knee or Hip

Sweden
Gebro Pharma GmbH

Completed

Dexibuprofen 400 mg Sachet Versus Ibuprofen 400 mg Sachet in Patients With Osteoarthritis of the Hip or Knee

Osteoarthritis of the Hip or Knee

Austria
Kneippsche Stiftungen
Otto-Schönfisch Foundation/ Bad Wörishofen/ Germany

Unknown

A Comparison of Kneipp Hydrotherapy With Conventional Physiotherapy in the Treatment of Osteoarthritis of the Hip or Knee: Protocol of a Prospective Randomised Controlled Clinical Trial

Osteoarthritis of the Hip or Knee

Germany
University of the Western Cape

Completed

Interventions for Patients With a Shortened Dental Arch (SDA-RCT)

Anomaly of Dental Arch

South Africa
Claudia Spies

Completed

DPNB vs. Modified DPNB With Ventromedial Infiltration (DPNB According to Dalens' Technique)

Circumcision, Meatotomy or Distal Coronary Correction of Hypospadia

Germany
National Cancer Institute (NCI)

Completed

Vaccine Therapy With or Without Sargramostim in Treating Patients With Advanced or Metastatic Cancer

Ovarian Endometrioid Adenocarcinoma | Adenocarcinoma of the Pancreas | Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | Male Breast Cancer | Stage IV Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Recurrent Breast Cancer | Stage IV Colon Cancer | Stage IV Rectal Cancer and other conditions

United States
Duke University

Completed

Impact of Body Habitus (Arm Span and Abdominal Girth) on Activities of Daily Living (ADL) (ADL)

Spinal Fusion | Activities of Daily Living Following Complex Spinal Fusions

United States
Wakayama Medical University

Unknown

Predictive Risk Factors for Pancreatic Fistula Grade C After Pancreaticoduodenectomy

Disease of Pancreatic Head or Periampullary Lesions to Require Pancreaticoduodenectomy

Taiwan
Peking University People's Hospital
Hangzhou Newhorizon Health Technology Co., Ltd.; Hangzhou Mingze Medical Research... and other collaborators

Recruiting

Clinical Evaluation of Detection of High Risk HPV in Urine (Urine-hrHPV)

Cervical Cancer | Cervical Adenocarcinoma | Cervical Squamous Cell Carcinoma | Human Papillomavirus Infection | Human Papilloma Virus | Adenocarcinoma in Situ | High-Grade Squamous Intraepithelial Lesions | Cervical Intraepithelial Neoplasia Grade II | Cervical Intraepithelial Neoplasia, Grade III | Atypical... and other conditions

China
Peking University People's Hospital
BeijingNewBiorayTechnologyCo.,Ltd.; Hangzhou Newhorizon Health Technology Co...

Active, not recruiting

Primary Cervical Cancer Screening by Self-sampling HPV Test (PREVENT)

Cervical Cancer | Cervical Adenocarcinoma | Cervical Squamous Cell Carcinoma | Human Papillomavirus Infection | Adenocarcinoma in Situ | Low-Grade Squamous Intraepithelial Lesions | High-Grade Squamous Intraepithelial Lesions | Cervical Intraepithelial Neoplasia Grade II | Cervical Intraepithelial Neoplasia... and other conditions

China
AZ Sint-Jan AV

Recruiting

Validation of the O-bridge Protocol: a Prospective, Multicenter Trial

Quality of Life | Mandibular Reconstruction | Benign or Malignant Tumour of the Oral Cavity | Stage III-IV Osteonecrosis | Fixed Dental Restoration

Belgium
Arthrex, Inc.

Recruiting

Evaluate the Continued Safety and Performance of the Foot and Ankle Products

Hyperpronated Foot | Reconstruction Surgeries of the Foot | Fixation of Fractures and Fusion (Bunionectomy Osteotomies) of the Foot/Ankle | Fixation of Small Bone Fragments of the Foot/Ankle | Lisfranc Arthrodesis | Mono or Bi-cortical Osteotomies in the Forefoot | First Metatarsophalangeal Arthrodesis and other conditions

Germany, United States, South Africa
University of Washington
National Institute of Nursing Research (NINR)

Completed

Integrating Palliative and Critical Care (IPACC) Study (IPACC)

Any Disease Causing Death in the ICU or Within 24 Hours of Discharge From the ICU

United States

Clinical Trials on Disease or Lesions of the Anus, Rectum, or Distal Colon

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