Clinical Trials on Disuse Atrophy (Muscle) of Lower Extremities

Total 381 results

Bispebjerg Hospital

Recruiting

The Impact of Bed Rest, Aging and NMES on Skeletal Muscle

Muscle Function | Neuromuscular Electrical Stimulation | Disuse Atrophy (Muscle) of Lower Extremities | Myofibrillar Protein Synthesis

Denmark
McMaster University

Completed

The Regulation of Human Skeletal Muscle Mass by Contractile Perturbation (HYPAT)

Muscle Atrophy | Disuse Atrophy (Muscle) of Lower Leg

Canada
Maastricht University Medical Center

Not yet recruiting

Current Practice of Patients Undergoing C-arm Procedures at the Operating Department

Types of C-arm Procedures Included | Low Complex (Lower & Upper Extremities) | High Complex (Lower Extremities & Spinal Cord)
United States Army Research Institute of Environmental...

Recruiting

Molecular Mechanisms Underlying Anabolic Resistance to Protein Intake During Muscle Disuse

Muscular Disorders, Atrophic | Muscle Atrophy | Disuse Atrophy | Atrophy, Disuse | Disuse Atrophy Muscle of Thigh

United States
The Touro College and University System

Recruiting

An Osteopathic Assessment of Lower Extremity Somatic Dysfunction in Runners

Somatic Dysfunction of Sacral Region | Somatic Dysfunction of Both Sacroiliac Joints | Somatic Dysfunction of Bilateral Lower Extremities

United States
McMaster University

Unknown

n3 PUFA and Muscle-disuse Atrophy in Older Women

Sarcopenia | Muscle Atrophy | Muscle Disuse Atrophy

Canada
McGill University

Recruiting

Examining Sex-based Differences in Metabolic and Mechanistic Responses to Disuse Induced Muscle Atrophy

Muscle Atrophy | Muscle Disuse Atrophy

Canada
University of Birmingham

Completed

Can Supplemental Leucine Offset Disuse-induced Muscle Atrophy? (LEU-DIMA)

Muscle Disuse Atrophy

United Kingdom
The University of Texas Health Science Center at...
National Institute on Aging (NIA)

Recruiting

Sex-specific Determinants of Early-phase Recovery From Skeletal Muscle Disuse (MAC)

Rehabilitation | Atrophy of Muscle Due to Disuse

United States
Texas Christian University

Recruiting

Strength Training Augmenting Rehabilitation (STAR)

Muscle Disuse Atrophy

United States
University of Exeter

Completed

Muscle Damage and Disuse Atrophy

Muscle Disuse Atrophy

United Kingdom
McMaster University

Recruiting

The Effects of Protein Supplementation With or Without Urolithin A During Single-leg Immobilization

Healthy | Muscle Disuse Atrophy

Canada
McMaster University
Myos Corporation

Completed

Effect of a Natural Source Supplementation on Muscle Mass

Nutrition, Healthy | Muscle Disuse Atrophy

Canada
University of Washington
Exelixis

Active, not recruiting

Cabozantinib With Radiation Therapy for the Treatment of Sarcomas of the Extremities

Stage I Soft Tissue Sarcoma of the Trunk and Extremities | Stage II Soft Tissue Sarcoma of the Trunk and Extremities | Sarcoma of the Extremity | Stage IA Soft Tissue Sarcoma of the Trunk and Extremities | Stage IB Soft Tissue Sarcoma of the Trunk and Extremities

United States
South Dakota State University
Sanford Research

Completed

The Efficacy of Protein Supplementation on Attenuating Muscle Atrophy Following Disuse in the Collegiate Population

Disuse Atrophy

United States
M.D. Anderson Cancer Center

Recruiting

Evaluating the Impact of Limited Compared With Intense Post-Operative Surveillance on Patient-Reported Outcomes in Patients With Stage II-III Soft Tissue Sarcoma of the Trunk and Extremities

Stage II Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage IIIA Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage IIIB Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Individualized Prehabilitation for Enhancing Recovery and Surgical Outcomes in Patients Undergoing Radiotherapy and Surgery for Soft Tissue Sarcoma

Soft Tissue Sarcoma | Stage I Soft Tissue Sarcoma of the Trunk and Extremities | Stage II Soft Tissue Sarcoma of the Trunk and Extremities | Stage III Soft Tissue Sarcoma of the Trunk and Extremities

United States
McMaster University
University of Guelph

Completed

n3 PUFA and Muscle-disuse Atrophy in Young Women

Muscle Atrophy

Canada
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Shorter Course, Hypofractionated Pre-Surgery Radiation Therapy in Treating Patients With Localized, Resectable Soft Tissue Sarcoma of the Extremity of Superficial Trunk

Stage II Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage IIIA Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage IIIB Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Resectable... and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Radiation Therapy Before Surgery for Localized, Resectable Soft Tissue Sarcoma of the Extremity and Superficial Trunk

Stage II Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Resectable Soft Tissue Sarcoma | Stage I Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage IA Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage IB Soft Tissue Sarcoma of the Trunk and Extremities...

United States
Bispebjerg Hospital

Recruiting

Prehabilitative Exercise Prior to Immobilization (PREHAB)

Sarcopenia | Disuse Atrophy | Skeletal Muscle Atrophy

Denmark
Maastricht University Medical Center

Terminated

Neuromuscular Electrical Stimulation During Immobilization Due to Ankle Fractures (ANKL-ES)

Immobilization | Muscle Disuse Atrophy

Netherlands
University of Padova

Completed

The ERASMUS Study: Limited vs Extended US for DVT Diagnosis

Deep Vein Thrombosis of the Lower Extremities
University of Birmingham
University of Nottingham; Biotechnology and Biological Sciences Research Council

Completed

Preventing Bed-rest Induced Muscle Loss in the Elderly

Sarcopenia | Muscle Loss | Prehabilitation | Disuse Atrophy | Protein Metabolism

United Kingdom
Amsterdam UMC, location VUmc

Completed

Expiratory Muscle Function in Critically Ill Ventilated Patients (EMFIC)

Critical Illness | Muscle Atrophy or Weakness | Mechanical Ventilation | Diaphragm | Expiratory Muscle

Netherlands
Kirby Mayer
Nathan Johnson, PT, PhD; Ashley Montgomery-Yates, MD; Amy Pastva, PT, PhD; Peter...

Withdrawn

Redefining Survivorship: POWER to Maximize Physical Function for Survivors of Critical Illness (POWER)

Critical Illness | Muscle Atrophy or Weakness

United States
Rutgers, The State University of New Jersey

Recruiting

YOOMI: Effect of Gamified Physical Therapy Exercise Software on Inpatient Mobility (YOOMI)

Physical Disability | Muscle Atrophy or Weakness | Muscle Loss | Physical Inactivity | Delirium in Old Age | Hospital Acquired Condition | Weakness, Muscle

United States
National Taiwan Sport University

Completed

The Effect of Supplementing Different Solutions on Firefighters' Simulated Fire Rescue Training

Injury of Multiple Muscles and Tendons at Lower Leg Level

Taiwan
University of Oregon
National Institute on Aging (NIA); Oregon Health and Science University; University... and other collaborators

Unknown

Mechanistic Approach to Preventing Atrophy and Restoring Function in Older Adults

Quality of Life | Muscle Atrophy

United States
Tao Zhang

Completed

Effects of Anesthetics on Postoperative Cognitive Function of Patients Undergoing Endovascular Repair of Aortic Aneurysm and Endovascular Treatment of Arteriosclerosis Obliterans of Lower Extremities.

Endovascular Repair of Aortic Aneurysm | Endovascular Treatment of Arteriosclerosis Obliterans of Lower Extremities

China
Bispebjerg Hospital

Completed

Biomarkers for Length of Hospital Stay and Loss of Muscle Mass and Function in Old Medical Patients (PROTECT)

Sarcopenia | Muscle Loss | Length of Stay

Denmark
Insel Gruppe AG, University Hospital Bern
Swiss National Science Foundation; Hôpital Fribourgeois; Kantonsspital Baden

Recruiting

An INtervention TO Improve MOBility of Older Hospitalized Patients (INTOMOB)

Iatrogenic Disease | Sarcopenia | Hospital Mobility | Mobility Limitation | Life-Space | Functional Status | Hospital-Acquired Condition | Muscle Atrophy or Weakness

Switzerland
University of Michigan
Hospital for Special Surgery, New York

Completed

Evaluation of rGH Therapy to Prevent Muscle Atrophy in Patients With ACL Tears

Rupture of Anterior Cruciate Ligament

United States
Faculdade de Ciências Médicas da Santa Casa de...

Recruiting

Efficacy of the Aussie Current in Patients With Knee Osteoarthritis.

Osteoarthritis, Knee | Quadriceps Muscle Atrophy

Brazil
Universidade Federal de Sao Carlos

Completed

Study of Effects of Low Level Laser Therapy in the Physical Training and the Muscle Responses in Humans.

Healthy Young Male Volunteers | Non Athletes | Free of Metabolic Disease | Joint, Bone and Muscles of Lower Limbs Free of Any Disease

Brazil
Hacettepe University

Completed

Investigation of Thenar Muscles Morphometric Parameters in Patients With TMC OA

Muscle Atrophy or Weakness | Thumb Osteoarthritis

Turkey
Meshalkin Research Institute of Pathology of Circulation

Terminated

Angioplasty of the Tibial Arteries Augmented Radio Frequency Denervation of the Popliteal Artery (ATRFPA)

Сhronic Ischemia of the Lower Extremities | Atherosclerosis of the Tibial Arteries | Lesion no More Than Two Tibial Arteries | Steno-occlusive Lesion of the Tibial Arteries

Russian Federation
Oliver Faude

Recruiting

Agility Training for Older Adults to Improve Fall Risk Factors (AgilE)

Sarcopenia | Aging | Cognitive Decline | Age-Related Loss of Skeletal Muscle Mass

Switzerland
Majmaah University
Scientific research unit, AIHMS New Delhi

Completed

Effect of Physical Therapy Modalities in Osteoarthritis

Osteo Arthritis Knee | Quadriceps Muscle Atrophy

India
Kessler Foundation
The Craig H. Neilsen Foundation

Unknown

Activity Dependent Rehabilitation Model to Improve Bone and Muscle Outcomes

Skeletal Muscle Hypertrophy | Nervous System | Atrophy, Disuse | Disuse Osteoporosis | Structural; Marker

United States
Abramson Cancer Center of the University of Pennsylvania

Terminated

Proton Radiotherapy for Extremity Soft Tissue Sarcoma

Soft Tissue Sarcoma of the Extremities

United States
University Hospital, Montpellier
APARD Fonds de dotation

Completed

Micro-environment Involvement in Muscle Alteration Induced (MicAMI-BPCO)

Chronic Obstructive Pulmonary Disease | Exacerbations | Skeletal Muscle Atrophy

France
Tufts Medical Center

Not yet recruiting

Relationship Between Protein Intake and ICU Skeletal Muscle Weakness

Atrophy of Rectus Femoris Muscle (Physical Finding)
Sahlgrenska University Hospital, Sweden
Vastra Gotaland Region

Recruiting

The Role of Surgical Approach on Residual Limping After Total Hip Arthroplasty (HSS)

Muscle Weakness | Muscle Atrophy | Hip Osteoarthritis | Arthroplasty Complications | Muscle Injury

Sweden
Guy's and St Thomas' NHS Foundation Trust

Completed

The Use of Computed Tomography (CT) to Measure Skeletal Muscle Quantity and Quality in Patients Receiving ECMO

Critical Illness | Muscle Atrophy

United Kingdom
Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI); Highlight Therapeutics

Active, not recruiting

Nivolumab and BO-112 Before Surgery for the Treatment of Resectable Soft Tissue Sarcoma

Leiomyosarcoma | Malignant Peripheral Nerve Sheath Tumor | Synovial Sarcoma | Undifferentiated Pleomorphic Sarcoma | Undifferentiated High Grade Pleomorphic Sarcoma of Bone | Myxofibrosarcoma | Stage II Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage III Soft Tissue Sarcoma of the... and other conditions

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Cemiplimab to Palbociclib for the Treatment of Advanced Dedifferentiated Liposarcoma

Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Advanced Dedifferentiated Liposarcoma | Metastatic Dedifferentiated Liposarcoma | Locally Advanced Dedifferentiated Liposarcoma | Unresectable Dedifferentiated...

United States
National Cancer Institute (NCI)

Not yet recruiting

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

Undifferentiated Pleomorphic Sarcoma | Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8 | Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8
Roswell Park Cancer Institute
Incuron

Terminated

CBL0137 in Treating Patients With Advanced Extremity Melanoma or Sarcoma

Clinical Stage III Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIB Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Clinical Stage IV Cutaneous Melanoma AJCC v8 | Pathologic Stage IV Cutaneous Melanoma AJCC v8 | Stage III Soft Tissue Sarcoma of the Trunk and... and other conditions

United States
Hasselt University
Jessa Hospital

Completed

Skeletal Muscle Wasting in SARS-CoV-2 (SMW)

Critical Illness | Cachexia | Muscle Atrophy | Muscle Loss | Muscle Wasting

Belgium

Clinical Trials on Disuse Atrophy (Muscle) of Lower Extremities

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