Clinical Trials on Down's Syndrome

Total 34253 results

The George Washington University Biostatistics...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy (SLEEP)

Obstructive Sleep Apnea of Adult | Preeclampsia | Obstetrical Complications

United States
St. Joseph's Hospital and Medical Center, Phoenix

Terminated

Effect of Oral Propranolol on mRNA Expresssion in Symptomatic Cavernous Malformation

Cerebral Cavernous Malformations

United States
The Miriam Hospital
Brown University; Brigham and Women's Hospital; Rhode Island Hospital; Women and...

Active, not recruiting

Positive Airway Pressure, Sleep Apnea, and the Placenta (PAP-SAP) (PAP-SAP)

Obesity | Sleep | Obstructive Sleep Apnea | Pregnancy | Preeclampsia

United States
Hospital Universitario de Fuenlabrada
Spanish Association of Surgeons (AEC)

Active, not recruiting

Gastric Bypass With Different Lengths of the Bilipancreatic Limb (BPG-1)

Hypertension | Obesity | Diabetes Mellitus, Type 2 | Dyslipidemias | Sleep Apnea | Laparoscopic-Roux-en-Y Gastric Bypass

Spain
National University Health System, Singapore

Completed

Routine Transcervical Thymectomy in MEN-1 Patients

Thymic Carcinoid | Multiple Endocrine Neoplasia Type 1 (MEN-1)

Singapore
Chinese Pulmonary Vascular Disease Research Group

Completed

The Effects of Obstructive Sleep Apnea and Its Intervention on Coronary Heart Disease

Hypertension | Metabolic Disorder
T. van der Poll
ZonMw: The Netherlands Organisation for Health Research and Development; Prothya...

Terminated

C1-inhibitor in Allergic ASThma Patients (CAST)

Asthma

Netherlands
John Hunter Hospital
Newcastle University; Hunter Medical Research Institute

Completed

The Effect of Haemodialysis in Sleep Apnoea

Sleep | Renal Failure | Sleep Disturbance | End Stage Kidney Disease | Sleep Disorders | Sleep Apnoea

Australia
Mid-Atlantic Epilepsy and Sleep Center, LLC

Unknown

Ketogenic Diet Treatment of Obesity With Co-morbid Type 2 Diabetes Mellitus and/or Obstructive Sleep Apnea (KGDobesity)

Obesity | Diabetes | Obstructive Sleep Apnea

United States
Assistance Publique - Hôpitaux de Paris

Completed

High Blood Pressure and Sleep Apnea in Diabetic Macular Edema (OMHADIA)

Diabetic Retinopathy

France
Novartis Pharmaceuticals

Completed

Expanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic Iron Overload

Myelofibrosis | Sickle Cell Disease | Thalassemia | Diamond Blackfan Anemia

United States, Netherlands, Taiwan, Thailand, Italy, Germany, Spain, Canada, Belgium, Greece, Turkey, United Kingdom
University of Roma La Sapienza
University of Milan; Azienda Policlinico Umberto I; Pavia IRCCS Mondino di Pavia

Recruiting

Personality, Defences, Central Sensitization, and Trauma in Women With Chronic Migraine, Fibromyalgia, and Vulvodynia (PSYCHOFIBRO)

Fibromyalgia | Vulvodynia | Chronic Migraine, Headache

Italy
Chang Gung Memorial Hospital
Ministry of Science and Technology, Taiwan

Recruiting

Brain Tissue Integrity and Autonomic Function Alterations in Childhood OSA and ADHD, and After Adenotonsillectomy.

Attention-deficit/Hyperactivity Disorder | Autonomic Nervous System Imbalance | Obstructive Sleep Apnea of Child

Taiwan
The University of Queensland

Recruiting

The TELO-SCOPE Study: Attenuating Telomere Attrition With Danazol. Is There Scope to Dramatically Improve Health Outcomes for Adults and Children With Pulmonary Fibrosis

Pulmonary Fibrosis | Dyskeratosis Congenita | Telomere Shortening | Telomere Disease

Australia
Christian von Buchwald
Bispebjerg Hospital

Recruiting

NO Measurements in Screening for Asthma and OSA, in Patients With CRSwNP

Asthma | Obstructive Sleep Apnea | Chronic Rhinosinusitis (Diagnosis) | Nasal Polyps | Inflammatory Disease | Airway Disease | Concomitant Disease

Denmark
University of Calgary

Not yet recruiting

Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia

Stroke | Sleep Disorder | Sleep Apnea | Blood Pressure | Endothelial Dysfunction | Oxidative Stress | Obstructive Sleep Apnea of Adult | Hypoxia, Brain
Scripps Translational Science Institute
Cue Health

Active, not recruiting

ImmunoCARE: Rapid, Accurate COVID Testing to Reduce Hospitalization of Immunocompromised Individuals

HIV Infections | Lymphoma | Leukemia | Cancer | Multiple Myeloma | Immunosuppression | Immunodeficiency | Transplant | Graft Versus Host Disease | Age-Related Immunodeficiency

United States
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Vincristine, Dactinomycin, and Doxorubicin With or Without Radiation Therapy or Observation Only in Treating Younger Patients Who Are Undergoing Surgery for Newly Diagnosed Stage I, Stage II, or Stage III Wilms' Tumor

Stage I Kidney Wilms Tumor | Stage II Kidney Wilms Tumor | Stage III Kidney Wilms Tumor

United States, Canada, Australia, New Zealand, Puerto Rico, Israel, Switzerland
Regeneron Pharmaceuticals

Available

Compassionate Use of Pozelimab

Paroxysmal Nocturnal Hemoglobinuria (PNH) | CD55-deficient Protein-losing Enteropathy (PLE) | CD59 Deficiency
Wuhan Union Hospital, China

Completed

Ventilation Modalities and Acute Ischemic Stroke

Sleep Apnea, Obstructive | Acute Ischemic Stroke

China
Centre Hospitalier Universitaire Saint Pierre

Completed

Pertussis Immunization During Pregnancy & HIV Infection

Pertussis | Pregnancy | HIV-1-infection | Immunization; Infection

Belgium
Murdoch Childrens Research Institute
Royal Children's Hospital

Completed

What is the Incidence of an Immune Disorder in Children With Invasive Pneumococcal Disease (IPD)?

Primary Immunodeficiency | Invasive Pneumococcal Disease, Protection Against | Invasive Pneumococcal Disease, Recurrent Isolated, 1 | Invasive Pneumococcal Disease, Recurrent Isolated, 2

Australia, New Zealand
Johns Hopkins University
Fusion Health

Completed

Recruitment Strategies Comparing Different Strategies in Sleep Apnea and Prediabetes

Sleep Disorder | Obstructive Sleep Apnea | Pre Diabetes

United States
Imperial College London
Royal Brompton & Harefield NHS Foundation Trust

Completed

Heart Function in Patients Assessed for Sleep Apnoea

Heart Failure | Obstructive Sleep Apnea | Sleep Disordered Breathing | Heart Failure With Preserved Ejection Fraction | Heart Failure With Normal Ejection Fraction | Central Sleep Apnea

United Kingdom
Diskapi Yildirim Beyazit Education and Research...

Unknown

The Effects of Covid-19 Pandemic on The Patients With Fibromyalgia

Fibromyalgia | Anxiety Depression | Sleep Quality | Covid-19 Fear | Covid-19 Anxiety | Daily Life

Turkey
UCSF Benioff Children's Hospital Oakland
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Medical... and other collaborators

Completed

Multi-Center Study of Iron Overload: Survey Study (MCSIO) (MCSIO)

Sickle Cell Disease | Thalassemia | Diamond-Blackfan Anemia

United States, United Kingdom, Germany
Vanderbilt University Medical Center

Completed

Mental Ability Challenge Study in Adults With and Without HIV

Cognitive Impairment | Memory Impairment | HIV-1-infection | Aging, Premature | HIV-Associated Cognitive Motor Complex

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Gene Expression Profiles to Categorize Wilms Tumors

Recurrent Wilms Tumor and Other Childhood Kidney Tumors | Stage III Wilms Tumor | Stage IV Wilms Tumor | Stage V Wilms Tumor | Stage I Wilms Tumor | Stage II Wilms Tumor

United States
Dana-Farber Cancer Institute

Completed

iCAT for Recurrent/Refractory/HR Solid Tumors

Sarcoma | Neuroblastoma | Wilms Tumor | Pediatric Solid Tumor

United States
Erling Bjerregaard Pedersen

Unknown

Nocturnal Blood Pressure and Hypertension - Central and Peripheral 24-h Blood Pressure. (HOSA)

Hypertension | Obstructive Sleep Apnea | Chronic Kidneys Disease

Denmark
Children's Cancer and Leukaemia Group

Unknown

Treatment Outcome and Quality of Life in Patients With Pediatric Extra-Cranial Germ Cell Tumors Previously Treated on Clinical Trial CCLG-GC-1979-01 or CCLG-GC-1989-01

Infertility | Ovarian Cancer | Sexual Dysfunction | Neurotoxicity | Long-term Effects Secondary to Cancer Therapy in Children | Gastrointestinal Complications | Urinary Complications | Pulmonary Complications | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

Ireland, United Kingdom
OMNI Medical Services, LLC
OMNI Medical Services Inc

Recruiting

Outcomes Mandate National Integration With Cannabis as Medicine (OMNI-Can)

Depression | COVID-19 | Epilepsy | Multiple Sclerosis | Glaucoma | Cancer | Covid19 | Chronic Pain | Parkinson Disease | Inflammatory Bowel Diseases | Hepatitis C | Insomnia | HIV/AIDS | Amyotrophic Lateral Sclerosis | Fibromyalgia | Anxiety | Bipolar Disorder | Seizures | Crohn Disease | Traumatic Brain Injury | Ulcerative Colitis | Sickle... and other conditions

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Terminated

CPI-613, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
National Cancer Institute (NCI)

Terminated

Flavopiridol in Treating Patients With Relapsed or Refractory Lymphoma or Multiple Myeloma

Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent... and other conditions

United States
National Cancer Institute (NCI)

Terminated

Oxaliplatin, Ifosfamide and Etoposide in Treating Young Patients With Recurrent or Refractory Solid Tumors or Lymphoma

Unspecified Childhood Solid Tumor, Protocol Specific | Peripheral T-cell Lymphoma | Angioimmunoblastic T-cell Lymphoma | Hepatosplenic T-cell Lymphoma | Intraocular Lymphoma | Recurrent Childhood Acute Lymphoblastic Leukemia | Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma | Recurrent Mycosis Fungoides... and other conditions

United States
Fred Hutchinson Cancer Research Center/University...
National Cancer Institute (NCI)

Completed

Internet-Based Program With or Without Telephone-Based Problem-Solving Training in Helping Long-Term Survivors of Hematopoietic Stem Cell Transplant Cope With Late Complications

Depression | Fatigue | Primary Myelofibrosis | Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone... and other conditions

United States
National Cancer Institute (NCI)

Completed

17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Advanced Epithelial Cancer, Malignant Lymphoma, or Sarcoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Novartis Pharmaceuticals

Completed

RAMSETE: RAD001 in Advanced and Metastatic Silent Neuro-endocrine Tumors in Europe (RAMSETE/CDE16)

Carcinoma | Neuroendocrine | Advanced and Metastatic Silent Neuro-Endocrine Tumors | Non Functioning Neuroendocrine Tumors (NETs) | Non Syndromic Neuroendocrine Tumors | Carcinoids | Non Functioning

Sweden, Italy, Germany, United Kingdom, Spain, France, Netherlands, Poland
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Mycophenolate Mofetil and Cyclosporine in Reducing Graft-Versus-Host Disease in Patients With Hematologic Malignancies or Metastatic Kidney Cancer Undergoing Donor Stem Cell Transplant

Clear Cell Renal Cell Carcinoma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent... and other conditions

United States, Germany, Italy
Children's Oncology Group

Not yet recruiting

A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

Stage I Kidney Wilms Tumor | Stage II Kidney Wilms Tumor | Stage III Kidney Wilms Tumor | Stage IV Kidney Wilms Tumor
Betta Pharmaceuticals Co., Ltd.

Not yet recruiting

A Study of BPI-452080 in Subjects With Solid Tumors

Renal Cell Carcinoma | Solid Tumor | Von Hippel-Lindau Disease

China
M.D. Anderson Cancer Center

Recruiting

Variables That Are Correlated to Developing Multiple Endocrine Neoplasia (MEN) and Pancreatic Neuroendocrine Tumors (PNET)

Hyperparathyroidism | Multiple Endocrine Neoplasia | Pancreatic Neuroendocrine Tumors

United States
University Health Network, Toronto
Sunnybrook Health Sciences Centre; Western University

Completed

Untreated Sleep Apnea as an Aggravating Factor for Other Secondary Medical Conditions After Spinal Cord Injury

Sleep Apnea | Neuropathic Pain | Spinal Cord Injuries | Spasticity, Muscle | Cardiovascular Complication

Canada
Assistance Publique - Hôpitaux de Paris

Completed

Vascular Thrombus Involvement in Nephroblastoma (VIN)

Nephroblastoma With Vena Cava Thrombosis

France
University of Saskatchewan

Completed

Efficacy of Opioid-free Anesthesia in Reducing Postoperative Respiratory Depression in Children Undergoing Tonsillectomy

Pathologic Processes | Postoperative Complications | Sleep Disordered Breathing | Anesthesia | Ketamine | General Anesthesia | Dexmedetomidine | Tonsillectomy | Respiratory Depression | Analgesics, Opioid | Pulse Oximetry | Lidocaine | Analgesics | Gabapentin | Narcotics | Obstructive Sleep Apnea of Child | Physiologic Effects...

Canada
VA Office of Research and Development

Completed

Treatment of Sleep-disordered Breathing in Patients With SCI

Multiple Sclerosis | Spinal Cord Injury | Sleep-disordered Breathing | Spinal Cord Disease

United States
Hospital Universitario La Paz

Completed

CPAP Effect on Albuminuria in Patients With Diabetic Nephropathy and Obstructive Sleep Apnea (DIANA)

Diabetic Nephropathy | Sleep Apnea

Spain
University of Birmingham
Heart of England NHS Trust

Completed

Obstructive Sleep Apnoea in Patients With Type 1 Diabetes

Type 1 Diabetes | Obstructive Sleep Apnoea

United Kingdom
The Cooper Health System

Unknown

Association of Hypertensive Disorder of Pregnancy With Sleep-disordered Breathing.

Sleep-disordered Breathing | Hypertensive Disorder of Pregnancy

United States
University Hospital, Clermont-Ferrand

Completed

Correlation Between Clinical and Electrophysiological Phenotypes in a Population of Patients With Neuropathy Charcot-Marie-Tooth Disease Type 1A (CCA1)

Charcot-Marie-Tooth Type 1A Neuropathy

France

Clinical Trials on Down's Syndrome

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Congo

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations