Clinical Trials on Down S Syndrome in United Kingdom

Total 14227 results

HemaQuest Pharmaceuticals Inc.

Terminated

Effects of HQK-1001 in Patients With Sickle Cell Disease

Sickle Cell Disease | Sickle Cell Anemia | Sickle Cell Disorders | Hemoglobin S Disease | Sickling Disorder Due to Hemoglobin S

United States, Lebanon, Egypt, Canada, Jamaica
Hoffmann-La Roche

Completed

A Screening Protocol to Assess Adults and Adolescents With Down Syndrome for Eligibility For Upcoming Study of RG1662 (Study BP27832)

Down Syndrome

United States, Spain, Canada, New Zealand, Argentina, Mexico, Singapore
University of Nottingham
Medical Research Council; National Institute for Health Research, United Kingdom

Recruiting

Characterising Frailty Using Magnetic Resonance Imaging (PHENOFRIM)

Frail Elderly Syndrome | Frailty | Frailty Syndrome

United Kingdom
Silence Therapeutics plc

Withdrawn

Study in Beta-thalassaemia or Myelodysplastic Syndrome Patients to Investigate the Safety and Tolerability of SLN124

Non-transfusion-dependent Thalassemia | Low Risk Myelodysplastic Syndrome

United Kingdom, Bulgaria
Guy's and St Thomas' NHS Foundation Trust

Recruiting

Pathophysiology of Hypoventilation in Obesity and Effects of Bariatric Intervention (PHOEBI)

Obesity Hypoventilation Syndrome (OHS)

United Kingdom
Genethon
Institute of Child Health; Great Ormond Street Hospital for Children NHS Foundation...

Completed

Gene Therapy for Wiskott-Aldrich Syndrome (WAS)

Wiskott-Aldrich Syndrome

United Kingdom
King's College London

Completed

Azacytidine for the Treatment of Myelodysplastic Syndromes/Acute Myeloid Leukemia (MDS/AML) With High Risk (Chromosome 7 and or Complex) Cytogenetic Abnormalities

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute

United Kingdom
Imperial College London

Enrolling by invitation

Colonoscopy Check-up in People With Lynch Syndrome

Lynch Syndrome

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Completed

A Trial of Rehabilitation in Obesity Hypoventilation Syndrome (OHS)

Obesity Hypoventilation Syndrome

United Kingdom
University of Liverpool

Recruiting

Brief ES for Recovery of Autonomic Function in CES (BESCES)

Cauda Equina Syndrome

United Kingdom
Advocate Health Care

Completed

Parents as the Primary Sexuality Educators for Their Young Adults With Down Syndrome

Intellectual Disability | Parent-Child Relations | Down Syndrome | Sexuality

United States
The Whiteley Clinic
Bauerfeind

Recruiting

Study to Investigate the Influence of Compression Treatment in Patients With Pelvic Congestion Syndrome (PCS)

Pelvic Congestive Syndrome

United Kingdom
Blackpool Teaching Hospitals NHS Foundation Trust

Not yet recruiting

Subacromial Injections for Shoulder Subacromial Pain Syndrome - Anterolateral vs Posterior Approach

Shoulder Subacromial Pain Syndrome

United Kingdom
Cardiff and Vale University Health Board
South East Wales Trials Unit (SEWTU); Tenovus

Completed

Low Anterior Resection Syndrome and Rectal Irrigation Study (LARRIS)

Anterior Resection Syndrome

United Kingdom
Northwestern University
ArchieMD

Completed

An Interactive Informed Consent and Education Program for Pregnant Women

Pregnancy | Down Syndrome

United States
Medical Research Council

Completed

Combination Chemotherapy With or Without Filgrastim and/or Tretinoin in Treating Patients With Acute Myeloid Leukemia

Myelodysplastic Syndromes | Leukemia | Myelodysplastic/Myeloproliferative Neoplasms

United Kingdom
Thomas Edward Pidgeon
University of Birmingham

Unknown

Studying Finger-thumb Grip in Patients With Carpal Tunnel Syndrome

Carpal Tunnel Syndrome

United Kingdom
University of Aberdeen
NHS Grampian

Completed

Abdominal Cutaneous Nerve Entrapment Syndrome (ACNES)

Abdominal Pain | Abdominal Cutaneous Nerve Entrapment Syndrome

United Kingdom
PellePharm, Inc.

Completed

Trial of Patidegib Gel 2%, 4%, and Vehicle to Decrease the Number of Surgically Eligible Basal Cell Carcinomas in Gorlin Syndrome Patients

Basal Cell Nevus Syndrome

United Kingdom
Eunice Kennedy Shriver National Institute of Child...

Unknown

Down Syndrome - Comparison of Screening Methods in the 1st and 2nd Trimesters

Down Syndrome | Chromosome Abnormalities

United States
Royal Devon and Exeter NHS Foundation Trust

Withdrawn

Post-void Bladder Scanning in Acute Cauda Equina Syndrome

Polyradiculopathy

United Kingdom
Eisai Inc.
Pfizer

Terminated

Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 6 To 10

Cognitive Dysfunction | Down Syndrome

United States
Eisai Inc.
Pfizer

Terminated

Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 11 To 17

Cognitive Dysfunction | Down Syndrome

United States
University of Arizona
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Recruiting

Medications for Obstructive Sleep Apnea to Improve Cognition in Children With Down Syndrome (MOSAIC)

Obstructive Sleep Apnea | Down Syndrome

United States
Oregon Health and Science University
National Heart, Lung, and Blood Institute (NHLBI); University of Michigan; Children... and other collaborators

Enrolling by invitation

Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS) (TOPS-DS)

Obstructive Sleep Apnea | Down Syndrome

United States
University of Arizona
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Medications for Obstructive Sleep Apnea In Children With Down Syndrome (MOSAIC)

Obstructive Sleep Apnea | Down Syndrome

United States
Children's Hospital of Philadelphia
University of Pennsylvania; National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health (NIH) and other collaborators

Completed

Investigating the Experience of Living With Down Syndrome and Obstructive Sleep Apnea Syndrome (Stage 1)

Obstructive Sleep Apnea | Down Syndrome

United States
Massachusetts General Hospital

Recruiting

Fluoxetine Treatment of Depression in Down Syndrome

Depression | Down Syndrome

United States
Children's Hospital Medical Center, Cincinnati

Completed

Treatment of Sleep Disturbances in School-age Children With Down Syndrome

Down Syndrome

United States
King's College Hospital NHS Trust
Alexandra Hospital, Athens, Greece

Completed

RCT of Laser Therapy for GSM

Genitourinary Syndrome of Menopause

United Kingdom
New York State Institute for Basic Research
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Unknown

Vitamin E in Aging Persons With Down Syndrome

Alzheimer Disease | Down Syndrome

United States, Canada, Australia, United Kingdom
Guy's and St Thomas' NHS Foundation Trust
Veryan Medical Ltd.

Recruiting

Structured Exercise Versus Endovascular Reconstruction in Post Thrombotic Syndrome (SEvERe-PTS)

Post Thrombotic Syndrome

United Kingdom
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Enrolling by invitation

Computer Models of Airways in Children and Young Adults With Sleep Apnea and Down Syndrome (DYMOSA)

Obstructive Sleep Apnea | Down Syndrome

United States
St George's, University of London
Bill and Melinda Gates Foundation; York Hospitals

Terminated

Reactogenicity and Immunogenicity of Vaginal CNgp140 (SG06RS02)

HIV Infections | Acquired Immune Deficiency Syndrome

United Kingdom
Celgene

Completed

Safety Study of Oral Azacitidine (CC-486) as Maintenance Therapy After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in Participants With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndromes (MDS).

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute

United States, United Kingdom
Advocate Health Care

Terminated

Learning by Repetitive Viewing of Peer Modeling Patient Education Videos by Adults With Down Syndrome

Down Syndrome | Trisomy 21

United States
Duke University
University of Florida; University of North Carolina, Chapel Hill; University...

Completed

Intensive Dysarthria Sessions in Adults and Children With Down Syndrome

Down Syndrome | Dysarthria

United States
NHS Greater Glasgow and Clyde
NHS Research Scotland

Recruiting

Clinical Characteristics and Subgroups in Greater Trochanteric Pain Syndrome

Greater Trochanteric Pain Syndrome

United Kingdom
University College, London
Cambridge University Hospitals NHS Foundation Trust; Sheffield Teaching Hospitals... and other collaborators

Active, not recruiting

Paediatric Sjögren Syndrome Cohort Study and Repository (PaedSSCoRe) (PaedSSCoRe)

Sjogren's Syndrome Childhood-onset

United Kingdom, Ireland
Womb Transplant UK
Oxford University Hospitals NHS Trust; Imperial College Healthcare NHS Trust

Recruiting

INvestigational Study Into Transplantation of the Uterus (INSITU)

Cervical Cancer | Postpartum Hemorrhage | Mayer-Rokitansky-Kuster Syndrome | Asherson's Syndrome

United Kingdom
University of Central Lancashire

Recruiting

Impact of 'SESL01' Lens on Computer Vision Syndrome

Computer Vision Syndrome

United Kingdom
Croydon University Hospital

Completed

Obstructed Defaecation: Proctography Versus Ultrasound in Symptomatic Patients (OPUS)

Obstructed Defaecation Syndrome

United Kingdom
University of Miami
University of Pennsylvania; National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health (NIH) and other collaborators

Recruiting

PAP for Children With DS and OSAS

Obstructive Sleep Apnea | Down Syndrome

United States
Cardiff and Vale University Health Board
Cambridge University Hospitals NHS Foundation Trust; University of Aarhus; University...

Completed

Translation of the International Consensus Definition of LARS Into a Bowl Dysfunction Severity Scoring Tool (New LARS Score)

Low Anterior Resection Syndrome

United Kingdom
Meharry Medical College
The University of Texas Health Science Center, Houston

Completed

Intense Education of Periodontal Health Maintenance

Chronical Periodontitis, Ratio of P. Gingivalis and S. Cristatus

United States
King's College Hospital NHS Trust

Completed

King's Invasive Aspergillosis Study II

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute | Bone Marrow Transplantation | Aplastic Anemia

United Kingdom
University of Washington

Completed

Use of Partial Body Weight Support Play Environment to Encourage Mobility and Exploration in Infants With Down Syndrome

Down Syndrome | Trisomy 21

United States
University of Pittsburgh
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Preventing Obesity Through Parent Empowerment and the Activation of Routines (PrO-PEAR) (PrO-PEAR)

Down Syndrome

United States
Progenity, Inc.
Obstetrix Medical Group

Unknown

Non-Invasive Screening for Fetal Aneuploidy

Down Syndrome | Edwards Syndrome

United States
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Down Syndrome Autonomic Nervous System Induction Bradycardia (DANSIB)

Bradycardia | Down Syndrome

United States

Clinical Trials on Down S Syndrome in United Kingdom

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