Clinical Trials on Down S Syndrome in United Kingdom

Total 14182 results

Sheffield Teaching Hospitals NHS Foundation Trust

Withdrawn

Study of the Vascular Response to Percutaneous Coronary Intervention in Patients With Non-ST-elevation Acute Coronary Syndromes Using Intravascular Blood Sampling (IN HEART)

Non ST Segment Elevation Acute Coronary Syndrome

United Kingdom
Natera, Inc.
Children's Hospital of Philadelphia; Montefiore Medical Center; University of... and other collaborators

Completed

SNP-based Microdeletion and Aneuploidy RegisTry (SMART) (SMART)

Prader-Willi Syndrome | DiGeorge Syndrome | 22q11 Deletion Syndrome | Angelman Syndrome | Trisomy 21 | Trisomy 18 | Trisomy 13 | Monosomy X | Sex Chromosome Abnormalities | 1p36 Deletion Syndrome | Cri-du-Chat Syndrome

United States, Australia, Ireland, Spain, Sweden, United Kingdom
University College, London

Unknown

TTP and aHUS in Complicated Pregnancies

Thrombotic Microangiopathies | Thrombotic Thrombocytopenic Purpura | Thrombocytopenia | Pre-Eclampsia | HELLP Syndrome | Stillbirth | Atypical Hemolytic Uremic Syndrome | IUGR

United Kingdom
DemeRx IB, Inc.
Hammersmith Medicines Research; ERT: Clinical Trial Technology Solutions; MAC...

Recruiting

A Study of Oral Ibogaine in Opioid Withdrawal

Opiate Withdrawal Syndrome

United Kingdom
University Hospitals Coventry and Warwickshire...
National Institute for Health Research, United Kingdom

Completed

TMJ Dysfunction Following Use of SAD

Temporomandibular Joint Disorder Bilateral

United Kingdom
Barts & The London NHS Trust
Imperial College London; Queen Mary University of London

Terminated

Metabolic Myopathy in Endocrinopathy (LYDIA)

Cushing Syndrome | Pheochromocytoma | Conns Syndrome | Metabolic Myopathy

United Kingdom
ElectroCore INC

Completed

A Randomized, Single Centre, Double-blind, Parallel, Sham-controlled Pilot Study Using gammaCore®-G

Dyspepsia | Irritable Bowel Syndrome

United Kingdom
Fortius Clinic

Unknown

Functional Improvement and UTC of the Achilles Tendon After Sodium Hyaluronate Injection for Plantaris Syndrome

Non-Insertional Achilles Tendinopathy | Plantaris Friction Syndrome

United Kingdom
Alizyme

Completed

Investigation of the Safety and Efficacy of Renzapride in Constipation Predominant Irritable Bowel Syndrome (IBS)

Irritable Bowel Syndrome

United Kingdom
Rottapharm

Completed

DARWIN Study: A Randomization/Withdrawal Efficacy Study of Dexloxiglumide in Constipation-Predominant Irritable Bowel Syndrome (C-IBS)

Irritable Bowel Syndrome

United Kingdom
University of Nottingham
King's College London

Completed

Carbohydrate Reduction and Impact on Gastrointestinal System (CRAIGS)

Irritable Bowel Syndrome

United Kingdom
ViiV Healthcare
GlaxoSmithKline

Completed

Absolute Bioavailability of BMS-626529 After Oral and Intravenous Dosing

Infection, Human Immunodeficiency Virus

United Kingdom
St Stephens Aids Trust

Completed

PK of Tenofovir, Emtricitabine and Efavirenz in Healthy Volunteers

HIV Infections | HIV Infection

United Kingdom
Sequenom, Inc.
PRA Health Sciences

Completed

Noninvasive Screening for Fetal Aneuploidy: A New Maternal Plasma Marker

Pregnancy | Down Syndrome | Aneuploidy | Edwards Syndrome

United States, France
National Eye Institute (NEI)

Terminated

Interferon Gamma-1b Administered Topically for Macular Edema/Intraretinal Schisis Cysts in Rod-Cone Dystrophy (RCD) and Enhanced S-Cone Syndrome (ESCS)

Inherited Retinal Degeneration | Inherited Ophthalmic Diseases

United States
Imperial College London

Completed

Service Development: Assessing Non-attendance Rates in Outpatient Clinics

Sleep Apnea Syndromes | Asthma | Tuberculosis | COPD

United Kingdom
ViiV Healthcare
GlaxoSmithKline

Completed

Bioavailability of BMS-626529 in Healthy Subjects From Prototype Low Dose Extended Release Formulations (Part 1) and Prototype Extended Release Multi-particulate Formulations (Part 2) of BMS-663068 Relative to 600 mg Extended Release Tablet

Infection, Human Immunodeficiency Virus

United Kingdom
ViiV Healthcare
GlaxoSmithKline

Completed

Relative Bioavailability Study With BMS-955176

Infection, Human Immunodeficiency Virus

United Kingdom
Glenn Gibson
Royal Berkshire NHS Foundation Trust

Recruiting

An Intervention Study Using HMOs to Improve IBS Symptoms (GUT-HEAL-IBS)

Irritable Bowel Syndrome

United Kingdom
Hazel Everitt
National Institute for Health Research, United Kingdom

Completed

Management of Irritable Bowel Syndrome in Primary Care (MIBS Trial) (MIBS)

Irritable Bowel Syndrome

United Kingdom
University of Nottingham

Completed

Fibre and Gas in Irritable Bowel Syndrome (EFIGI)

Irritable Bowel Syndrome

United Kingdom
Chelsea and Westminster NHS Foundation Trust
Gilead Sciences; Imperial College London

Terminated

Efficacy, Tolerability and Acceptability of Biktarvy by TPLWH

Human Immunodeficiency Virus

United Kingdom
Myota GmbH

Active, not recruiting

PRebiotic Intervention for Metabolic and MEntal Health (PRIME) (PRIME)

Stress | Metabolic Syndrome | Anxiety | Mood

United Kingdom
AbbVie
Genentech, Inc.

Active, not recruiting

A Study Evaluating Venetoclax in Combination With Azacitidine in Participants With Treatment-Naïve Higher-Risk Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndromes (MDS)

United States, Australia, Canada, France, Germany, Italy, United Kingdom
Leukemia Research Fund

Completed

Intensive Compared With Nonintensive Chemotherapy in Treating Older Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome

Myelodysplastic Syndromes | Leukemia | Myelodysplastic/Myeloproliferative Neoplasms

United Kingdom
Lexicon Pharmaceuticals

Completed

An Open-label Study to Evaluate the Absorption, Metabolism, and Excretion of [14C]-Telotristat Etiprate in Males (LX1606-104)

Carcinoid Syndrome

United Kingdom
Eisai Inc.
Pfizer

Completed

Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (HCl) (Aricept) In Treating Cognitive Dysfunction Exhibited By Children With Down Syndrome

Down Syndrome

United States
Vanderbilt University Medical Center

Completed

Strategies for Teaching Verbs

Down Syndrome | Language Development Disorders | Child Language

United States
University of East Anglia
Quadram Institute Bioscience; Invest in ME Research UK

Unknown

Autoimmunity in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

Chronic Fatigue Syndrome | Myalgic Encephalomyelitis

United Kingdom
University of Surrey
European Commission

Completed

A Safety Study Of A Single Vaginal Administration Of P2G12 Antibody In Healthy Female Subjects

Human Immunodeficiency Virus

United Kingdom
University of Nottingham
University Hospitals of Derby and Burton NHS Foundation Trust

Completed

Letrozole Versus Clomifene Citrate for Ovulation Induction

Infertility | Polycystic Ovarian Syndrome

United Kingdom
Sequenom, Inc.
Friends Research Institute, Inc.

Terminated

Clinical Performance of the MaterniT21 PLUS LDT in Multiple Gestation Pregnancies

Down Syndrome | Turner Syndrome | Edwards Syndrome | Patau Syndrome

United States
Imperial College London

Completed

Positive Attitudes Concerning Infant Feeding- a Questionnaire for Women Living With HIV (PACIFY)

Human Immunodeficiency Virus

United Kingdom
Manchester University NHS Foundation Trust
University of Manchester

Completed

The Feasibility, Acceptability and Clinical Utility of a New Remote-mobile Technology Intervention (ASARM) for CFS/ME in a Paediatric Population (ASARM)

Chronic Fatigue Syndrome

United Kingdom
Cambridge University Hospitals NHS Foundation Trust

Completed

The Role of Circuit Flow During Mechanical Ventilation of Neonates (E-Flow)

Respiratory Distress Syndrome in Premature Infant

United Kingdom
University of Chester

Recruiting

Diet, Cardiometabolic Risk (CM) and Menopause Symptoms

Menopause | Metabolic Syndrome, Protection Against

United Kingdom
Edinburgh Napier University
University of Dundee; The University of New South Wales; University of Aberdeen; University of Stirling

Unknown

Reducing Acute Coronary Syndrome Patient Delay (RAPiD)

Acute Coronary Syndrome

United Kingdom
Natera, Inc.

Completed

Development of Non-invasive Prenatal Screening Test for Microdeletions Based on Fetal DNA Isolated From Maternal Blood (MAPS)

Trisomy 21 | Trisomy 18 | Trisomy 13 | Sex Chromosome Abnormalities | Microdeletion Syndromes

United States, Spain, Taiwan
University of Ulster
Mayo Clinic; Belfast Health and Social Care Trust; Keele University; Northern Health...

Unknown

Exercise in the Physiotherapy Management of Shoulder Impingement (EaSI)

Subacromial Impingement Syndrome

United Kingdom
East and North Hertfordshire NHS Trust
University of Hertfordshire

Unknown

Can Very Low Dose Rivaroxaban in Addition to Dual Antiplatelet Therapy (DAPT) Improve Thrombotic Status in Acute Coronray Syndrome (ACS) ACS (VaLiDate-R)

Acute Coronary Syndrome

United Kingdom
London South Bank University
Guy's and St Thomas' NHS Foundation Trust

Completed

Acupuncture for the Treatment of Phantom Limb Syndrome

Phantom Limb Syndrome

United Kingdom
Novartis Pharmaceuticals

Recruiting

Ribociclib (LEE011) Rollover Study for Continued Access

Continued Access to Study Treatment(s), Cancers With a Mass, Bulky Tumor, Nodule, Lump, Advanced Cancer, Advanced Solid Tumors, Advanced Solid Malignancies

Spain, Taiwan, United States, Singapore, France
Women and Infants Hospital of Rhode Island
Sequenom, Inc.

Completed

A New Prenatal Blood Test for Down Syndrome (RNA)

Down Syndrome | Trisomy 21

United States, Canada, Israel, Hungary, Ireland, Argentina, Australia, Czech Republic, Italy, Spain
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Completed

Effects of Serotonin Excess on Bone in Carcinoid Syndrome

Carcinoid Syndrome

United Kingdom
London North West Healthcare NHS Trust

Unknown

Manipulation of Visceral Sensitivity and Immune System in IBS

Irritable Bowel Syndrome

United Kingdom
Drug Safety Research Unit, Southampton, UK

Completed

Rivaroxaban ACS Specialist Cohort Event Monitoring Study (ROSE ACS)

Acute Coronary Syndrome

United Kingdom
University of Nottingham
Norgine

Completed

Mode of Action of Moviprep

Functional Constipation | Irritable Bowel Syndrome Characterized by Constipation

United Kingdom
Liverpool University Hospitals NHS Foundation Trust
Liverpool Heart and Chest Hospital NHS Foundation Trust; Countess of Chester... and other collaborators

Completed

The Risk of Major Bleeding With Novel Anti-platelets: A Comparison of Ticagrelor With Clopidogrel in a Real World Population of 5000 Patients Treated for Acute Coronary Syndrome (ROBOT-ACS)

Bleeding | Acute Coronary Syndrome | Ticagrelor | Clopidogrel | Novel Anti-platelets

United Kingdom
University of Kansas Medical Center
National Institute on Aging (NIA)

Completed

The Promotion of Physical Activity for the Prevention of Alzheimer's Disease in Adults With Down Syndrome

Alzheimer Disease | Down Syndrome

United States
Imperial College London
University of Edinburgh; British Heart Foundation

Recruiting

Best Endovenous Treatment, Including STenting, Versus Non-endovenous Treatment in Chronic Proximal Deep Venous Disease (BEST)

Post Thrombotic Syndrome | Chronic Venous Insufficiency | Iliac Vein Obstruction | Chronic Venous Thrombosis | Iliac Vein Stenosis

United Kingdom

Clinical Trials on Down S Syndrome in United Kingdom

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Dominican Republic

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Rare Diseases

Drug Interventions

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