Clinical Trials on Down Syndrome in United Kingdom

Total 14198 results

Royal Devon and Exeter NHS Foundation Trust

Withdrawn

Post-void Bladder Scanning in Acute Cauda Equina Syndrome

Polyradiculopathy

United Kingdom
Eisai Inc.
Pfizer

Terminated

Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 6 To 10

Cognitive Dysfunction | Down Syndrome

United States
Eisai Inc.
Pfizer

Terminated

Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In The Treatment Of The Cognitive Dysfunction Exhibited By Children With Down Syndrome, Aged 11 To 17

Cognitive Dysfunction | Down Syndrome

United States
University of Arizona
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Recruiting

Medications for Obstructive Sleep Apnea to Improve Cognition in Children With Down Syndrome (MOSAIC)

Obstructive Sleep Apnea | Down Syndrome

United States
Oregon Health and Science University
National Heart, Lung, and Blood Institute (NHLBI); University of Michigan; Children... and other collaborators

Enrolling by invitation

Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS) (TOPS-DS)

Obstructive Sleep Apnea | Down Syndrome

United States
University of Arizona
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Medications for Obstructive Sleep Apnea In Children With Down Syndrome (MOSAIC)

Obstructive Sleep Apnea | Down Syndrome

United States
Children's Hospital of Philadelphia
University of Pennsylvania; National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health (NIH) and other collaborators

Completed

Investigating the Experience of Living With Down Syndrome and Obstructive Sleep Apnea Syndrome (Stage 1)

Obstructive Sleep Apnea | Down Syndrome

United States
New York State Institute for Basic Research
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Unknown

Vitamin E in Aging Persons With Down Syndrome

Alzheimer Disease | Down Syndrome

United States, Canada, Australia, United Kingdom
Guy's and St Thomas' NHS Foundation Trust
Veryan Medical Ltd.

Recruiting

Structured Exercise Versus Endovascular Reconstruction in Post Thrombotic Syndrome (SEvERe-PTS)

Post Thrombotic Syndrome

United Kingdom
King's College Hospital NHS Trust
Alexandra Hospital, Athens, Greece

Completed

RCT of Laser Therapy for GSM

Genitourinary Syndrome of Menopause

United Kingdom
St George's, University of London
Bill and Melinda Gates Foundation; York Hospitals

Terminated

Reactogenicity and Immunogenicity of Vaginal CNgp140 (SG06RS02)

HIV Infections | Acquired Immune Deficiency Syndrome

United Kingdom
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Enrolling by invitation

Computer Models of Airways in Children and Young Adults With Sleep Apnea and Down Syndrome (DYMOSA)

Obstructive Sleep Apnea | Down Syndrome

United States
Celgene

Completed

Safety Study of Oral Azacitidine (CC-486) as Maintenance Therapy After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in Participants With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndromes (MDS).

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute

United States, United Kingdom
Advocate Health Care

Terminated

Learning by Repetitive Viewing of Peer Modeling Patient Education Videos by Adults With Down Syndrome

Down Syndrome | Trisomy 21

United States
Duke University
University of Florida; University of North Carolina, Chapel Hill; University...

Completed

Intensive Dysarthria Sessions in Adults and Children With Down Syndrome

Down Syndrome | Dysarthria

United States
University College, London
Cambridge University Hospitals NHS Foundation Trust; Sheffield Teaching Hospitals... and other collaborators

Active, not recruiting

Paediatric Sjögren Syndrome Cohort Study and Repository (PaedSSCoRe) (PaedSSCoRe)

Sjogren's Syndrome Childhood-onset

United Kingdom, Ireland
NHS Greater Glasgow and Clyde
NHS Research Scotland

Recruiting

Clinical Characteristics and Subgroups in Greater Trochanteric Pain Syndrome

Greater Trochanteric Pain Syndrome

United Kingdom
University of Miami
University of Pennsylvania; National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health (NIH) and other collaborators

Recruiting

PAP for Children With DS and OSAS

Obstructive Sleep Apnea | Down Syndrome

United States
Womb Transplant UK
Oxford University Hospitals NHS Trust; Imperial College Healthcare NHS Trust

Recruiting

INvestigational Study Into Transplantation of the Uterus (INSITU)

Cervical Cancer | Postpartum Hemorrhage | Mayer-Rokitansky-Kuster Syndrome | Asherson's Syndrome

United Kingdom
University of Central Lancashire

Recruiting

Impact of 'SESL01' Lens on Computer Vision Syndrome

Computer Vision Syndrome

United Kingdom
Croydon University Hospital

Completed

Obstructed Defaecation: Proctography Versus Ultrasound in Symptomatic Patients (OPUS)

Obstructed Defaecation Syndrome

United Kingdom
University of Washington

Completed

Use of Partial Body Weight Support Play Environment to Encourage Mobility and Exploration in Infants With Down Syndrome

Down Syndrome | Trisomy 21

United States
Cardiff and Vale University Health Board
Cambridge University Hospitals NHS Foundation Trust; University of Aarhus; University...

Completed

Translation of the International Consensus Definition of LARS Into a Bowl Dysfunction Severity Scoring Tool (New LARS Score)

Low Anterior Resection Syndrome

United Kingdom
Guy's and St Thomas' NHS Foundation Trust

Completed

Remote Monitoring to Improve Low Adherence in Non-invasive Ventilation (READ-NIV)

Sleep Disordered Breathing | COPD | Hypercapnic Respiratory Failure | Obesity Hypoventilation Syndrome (OHS)

United Kingdom
Progenity, Inc.
Obstetrix Medical Group

Unknown

Non-Invasive Screening for Fetal Aneuploidy

Down Syndrome | Edwards Syndrome

United States
King's College Hospital NHS Trust

Completed

King's Invasive Aspergillosis Study II

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute | Bone Marrow Transplantation | Aplastic Anemia

United Kingdom
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Down Syndrome Autonomic Nervous System Induction Bradycardia (DANSIB)

Bradycardia | Down Syndrome

United States
University of Pittsburgh
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Preventing Obesity Through Parent Empowerment and the Activation of Routines (PrO-PEAR) (PrO-PEAR)

Down Syndrome

United States
University of Oxford

Terminated

Safety and Immunogenicity of a Candidate MERS-CoV Vaccine (MERS001)

MERS (Middle East Respiratory Syndrome)

United Kingdom
Massachusetts General Hospital
Patient-Centered Outcomes Research Institute

Completed

An Online Health Tool About Down Syndrome: Down Syndrome Clinic to You (DSC2U)

Down Syndrome

United States
Imperial College London
Homerton University Hospital NHS Foundation Trust

Withdrawn

Combining Physical Therapy With Vestibular Stimulation to Improve Postural Stability in Pusher's Syndrome

Pusher Syndrome

United Kingdom
Christopher Hartnick, M.D.
University of Pittsburgh; Emory University; Children's Hospital Medical Center... and other collaborators

Completed

A Pilot Study to Evaluate the Hypoglossal Nerve Stimulator in Adolescents With Down Syndrome and Obstructive Sleep Apnea

Sleep Apnea, Obstructive | Down Syndrome

United States
Genethon

Active, not recruiting

Long Term Safety Follow up of Haematopoietic Stem Cell Gene Therapy for the Wiskott Aldrich Syndrome (WASFUP)

Wiskott-Aldrich Syndrome

United Kingdom, France
King's College London
South London and Maudsley NHS Foundation Trust

Not yet recruiting

Exploring Worry in CFS/ME

Chronic Fatigue Syndrome

United Kingdom
The Royal Orthopaedic Hospital NHS Trust

Completed

The Experiences of Patients With Greater Trochanteric Pain Syndrome.

Greater Trochanteric Pain Syndrome

United Kingdom
University of Exeter

Not yet recruiting

Glymphatic MRI in Clinically Isolated Syndrome

Clinically Isolated Syndrome

United Kingdom
Manchester University NHS Foundation Trust
Northern Care Alliance NHS Foundation Trust; National Institute for Health... and other collaborators

Completed

Comparing Gamification With Remote Monitoring Against Standard Rehabilitation, for Patients After Arthroscopic Subacromial Decompression Surgery (GAME)

Subacromial Impingement Syndrome | Shoulder Impingement Syndrome

United Kingdom
Imperial College London

Withdrawn

Steroids and Antiphospholipid Syndrome- Related Pregnancy Loss

Antiphospholipid Syndrome

United Kingdom
University Hospital Plymouth NHS Trust

Completed

Is a Pre-contrast Scan Necesary to Diagnose Acute Aortic Syndrome?

Acute Aortic Syndrome

United Kingdom
Imperial College London
Medical Research Council

Completed

SWS And Daytime Functioning in Chronic FatiguE Syndrome (SAFFE) (SAFFE)

Chronic Fatigue Syndrome

United Kingdom
Kyowa Kirin, Inc.

Terminated

Study of KHK2823 in Patients With Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)

Acute Myeloid Leukemia | Myelodysplastic Syndrome

United Kingdom
Vanderbilt University Medical Center

Completed

Nicotine Treatment of Cognitive Decline in Down Syndrome

Down Syndrome | Mild Cognitive Impairment

United States
University of Michigan
National Institutes of Health (NIH)

Completed

A Bicycle Training Intervention

Autism Spectrum Disorder | Down Syndrome

United States
University of Nottingham

Unknown

Perfusion MRI in Reversible Cerebral Vasoconstriction Syndrome

Reversible Cerebral Vasoconstriction Syndrome

United Kingdom
National Institute of Diabetes and Digestive and...
University of Massachusetts, Worcester

Completed

Parent Supported Weight Reduction in Down Syndrome

Down Syndrome

United States
OPKO Health, Inc.
Elan Pharmaceuticals

Completed

A 4-Week Safety Study of Oral ELND005 in Young Adults With Down Syndrome Without Dementia (DS201)

Down Syndrome

United States
University of Ulster

Enrolling by invitation

Reading; Through the Eyes of a University Student

Visual Stress | Meares-Irlen Syndrome | Reading Difficulties

United Kingdom
LLS PedAL Initiative, LLC
National Cancer Institute (NCI); Children's Oncology Group

Recruiting

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Myeloid Leukemia Associated With Down Syndrome | Mixed Phenotype Acute Leukemia | Acute Myeloid Leukemia Post Cytotoxic Therapy | Myelodysplastic Syndrome Post Cytotoxic Therapy

United States, Canada, Australia, Puerto Rico, New Zealand
TC Biopharm

Recruiting

ACHIEVE - Efficacy and Effectiveness of Adoptive Cellular tHerapy wIth Ex-Vivo Expanded Allogeneic γδ T-lymphocytes (TCB008) for Patients With Refractory or Relapsed Acute Myeloid Leukaemia (AML) (ACHIEVE)

Acute Myeloid Leukemia | Myelodysplastic Syndromes

United Kingdom
Novartis

Terminated

Efficacy and Safety of Aliskiren/Ramipril/Amlodipine Compared With Ramipril/Amlodipine and Aliskiren/Amlodipine in Patients With Metabolic Syndrome (ALTO)

Hypertension With Metabolic Syndrome

United Kingdom

Clinical Trials on Down Syndrome in United Kingdom

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