Clinical Trials on Drug Action Increased in Netherlands

Total 129 results

University Medical Center Groningen
Boehringer Ingelheim; CSL Behring

Unknown

Reversal of Dabigatran With Prothrombin Complex Concentrate

Drug Action Reversal

Netherlands
Medical Centre Leeuwarden

Completed

Effect of Fluid Resuscitation and Microcirculation

Total Fluid Volume Increased

Netherlands
Leiden University Medical Center
bio.logis digital health GmbH

Recruiting

Personalised Therapeutics @LUMC (PT@LUMC)

Adverse Drug Reaction

Netherlands
Clementine CM Stuijt PharmD, MSc
Insurance company Achmea Zorg

Unknown

the Pharmacy Intervention Team Hospital-based (PITH) for People Study: Effect on Clinical and Economic Outcomes (PITH)

Medication Administered in Error | Adverse Drug Reaction

Netherlands
J.J.Swen
Karolinska Institutet; Medical University of Vienna; Uppsala University; St. Antonius... and other collaborators

Completed

PREemptive Pharmacogenomic Testing for Preventing Adverse Drug REactions (PREPARE)

Adverse Drug Reaction

Austria, Netherlands, Italy, Greece, Slovenia, Spain, United Kingdom
Chong Kun Dang Pharmaceutical

Completed

CKD-506 Drug-Drug Interaction Study in Healthy Male Subjects

Drug Drug Interaction

Netherlands
Asceneuron S.A.

Recruiting

Drug-Drug Interaction of ASN51 With Fluvoxamine, Itraconazole and Paroxetine in Healthy Subjects

Drug Drug Interaction

Netherlands
Maastricht University Medical Center

Completed

Proof of Concept Study; The Effect of an Encapsulated Nutrient Mixture on Ileal Brake Activation

Body Weight Decreased

Netherlands
Radboud University Medical Center
Astellas Pharma Inc

Recruiting

Determining the Clinical Relevance of the Interaction Between Enzalutamide and the Opioid Morphine and the DOAC Edoxaban (MIND THE GAP)

Drug-drug Interaction

Netherlands
Erasmus Medical Center

Recruiting

The Effect of a Laryngeal Mask Airway on Optic Nerve Sheath Diameter (ONSD laryngeal)

Intracranial Pressure Increase

Netherlands
F-star Therapeutics, Inc.
PRA Health Sciences

Completed

A Fixed-Sequence, Drug-Drug Interaction Study Between Multiple Oral Doses of Inarigivir Soproxil and a Single Oral Dose of Midazolam in Healthy Subjects

Drug Interaction Potentiation

Netherlands
The Netherlands Cancer Institute

Unknown

Food-effect Study on Uracil and Dihydrouracil Levels as a Diagnostic Marker of Dihydropyrimidine Dehydrogenase Activity

Drug Safety Biomarkers

Netherlands
Radboud University Medical Center
Amgen

Completed

Rivaroxaban Sotorasib Interaction Study (ROSIE)

Drug Drug Interaction Study

Netherlands
Reinier Haga Orthopedisch Centrum
Delft University of Technology

Recruiting

Propagation Waves in Tactile Material Perception

Sensory Processing | Perception | Sense of Touch | Taction

Netherlands
H.T. Ensing, PharmD, MSc
Flevoziekenhuis; Zorggroep Almere

Completed

The Effect of a Pharmacist Home Visit on Drug-related Problems Post-discharge. (HomeCoMe)

Adverse Drug Event | Readmission | Patient Compliance

Netherlands
University Medical Center Groningen

Completed

Drug Interaction Study Between Linezolid and Clarithromycin in Tuberculosis Patients

Multidrug-resistant Tuberculosis | Extensively Drug-resistant Tuberculosis

Netherlands
St. Antonius Hospital
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Completed

Pharmacokinetics of Morphine and Oxycodone in Frail Elderly Undergoing Cardiac Surgery

Postoperative Pain | Opioid Use | Side Effect of Drug

Netherlands
Leiden University
Bristol-Myers Squibb

Active, not recruiting

TIL and Anti-PD1 in Metastatic Melanoma (ACTME)

Effects of Immunotherapy | Adverse Drug Event | Toxicity, Drug

Netherlands
Radboud University Medical Center

Completed

Patient Journey Application for Discontinuing Inappropriate PPI Use: a Randomized Controlled Trial (SUPPORT)

Proton Pump Inhibitor | Inappropriate Drug Use | Discontinuation | E-health

Netherlands
Radboud University Medical Center

Completed

Sodium Lactate Infusion in GLUT1DS Patients

Epilepsy | Ketogenic Dieting | Lactic Acid Blood Increased | GLUT1DS1 | GLUT1 Deficiency Syndrome | GLUT1DS2

Netherlands
Radboud University Medical Center

Completed

Safety and Tolerability of Namisol in the Elderly (THC)

Drug Safety

Netherlands
GlaxoSmithKline
PRA Health Sciences for clinical study conduct.

Completed

A Positron Emission Tomography (PET) Imaging Study to Investigate the Biodistribution and Clearance of an Albumin Binding Domain Antibody (AlbudAb) GSK3128349 in Healthy Male Subjects

Drug-Related Side Effects and Adverse Reactions

Netherlands
Isala

Recruiting

Evaluating the Safety of Shortened Infusion Times for dIfferent Oncological Immunotherapie (MINUTE)

Oncology | Infusion Reaction

Netherlands
Zuyderland Medisch Centrum

Completed

Lumbar Intervertebral Motion in Asymptomatic Male Participants

Lumbar Intervertebral Motion

Netherlands
Erasmus Medical Center

Recruiting

Safe Stop Ipilimumab-nivolumab (IPI-NIVO) Trial

Immunotherapy | Melanoma Stage IV | Melanoma Stage III | Toxicity, Drug

Netherlands
Kontigo Care AB

Completed

A First Study in Healthy Volunteers of a New Mobile Phone Application Measuring the Eyes Before and After Medication

Drug Abuse

Netherlands
UMC Utrecht
Erasmus Medical Center; Academisch Medisch Centrum - Universiteit van Amsterdam... and other collaborators

Completed

The NeXT Study; The Netherlands XTC Toxicity Study

Psychopathology | Ecstasy (Drug) | N-Methyl-3,4-Methylenedioxymethamphetamine

Netherlands
Radboud University Medical Center

Completed

Exercise-induced Muscle Damage in Statin Users

Cardiovascular Diseases | Muscle Damage | HMG COA Reductase Inhibitor Adverse Reaction

Netherlands
Maxima Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

Intrapartum Non-invasive Electrophysiological Monitoring (NIEM-II)

Caesarean Section | Electrocardiography | Cardiotocography | Fetal Monitoring | Non-invasive

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

TACO Crossover TRIAL

Transfusion-associated Circulatory Overload | Blood Transfusion Reaction

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Practice of Adjunctive Treatments in Intensive Care Unit Patients With COVID-19 (PRoAcT-COVID)

Pneumonia | Covid19 | Thrombosis | Thromboembolism | ARDS, Human | Anticoagulants; Increased

Netherlands
Maastricht University
Netherlands Brain Foundation

Completed

Roflumilast to Treat Cognitive Sequela After Stroke (ROSTMEMA)

Cerebrovascular Disorders | Functional Recovery | Memory | Drug Intervention

Netherlands
UMC Utrecht

Unknown

REC2Stim as a Treatment for Refractory Epilepsy in the Primary Sensorimotor Cortex. (REC2Stim)

Epilepsy Intractable | Epileptic Seizure | Motor Seizure

Netherlands
Radboud University Medical Center
Canisius-Wilhelmina Hospital; Maas Hospital Pantein

Completed

Evaluating the Adherence Improving Self-Management Strategy Intervention in Chronic Heart Failure Patients (AIMS-CHF RCT)

Chronic Heart Failure | Heart Decompensation | Preserved Ejection Fraction | Reduced Ejection Fraction | Myocardial Failure

Netherlands
Epilepsiecentrum Kempenhaeghe
Maastricht University Medical Center

Unknown

Does VNS Interact With the Serotonergic and Immune System in Children With Intractable Epilepsy?

Refractory Epilepsy in Children

Netherlands
Air Liquide Santé International
Orion Corporation, Orion Pharma

Completed

Xenon Compared to Sevoflurane and Total Intravenous Anaesthesia for Coronary Artery Bypass Graft Surgery

Coronary Artery Disease | Coronary Artery Bypass Graft Surgery | General Anesthetic Drug Allergy

France, Italy, Germany, Netherlands
Thorax Centrum Twente

Completed

Change of Dual Antiplatelet Therapy in Patients With Acute Coronary Syndrome (CHANGE DAPT)

Acute Coronary Syndrome | Percutaneous Coronary Intervention | Drug-Eluting Stents

Netherlands
GGZ Centraal
University Medical Center Groningen; Maastricht University

Terminated

Deep Brain Stimulation for Patients With Tardive Dyskinesia and or Dystonia

Tardive Dyskinesia | Tardive Dystonia

Netherlands
Rijnstate Hospital

Completed

Anti-Xa Level With Thromboprophylactic Dosage Nadroparin in Critically Ill COVID-19 and Non-COVID-19 Patients (NADRO)

Critical Illness | Venous Thromboembolism | Therapeutic Drug Monitoring

Netherlands
University Medical Center Groningen

Completed

Timing of Maternal Antibiotic Prophylaxis During a Cesarean Section and the Early Infant Gut Microbiome (CSBabyBiome)

Microbial Colonization | Cesarean Section Complications | Antibiotic Side Effect

Netherlands
University Medical Center Groningen
Netherlands Heart Foundation

Completed

Effects of a Single Oral Dose of KETone Ester ON Exercise Performance in Patients With Chronic Heart Failure (KETONE-HF)

Heart Failure | Heart Failure With Reduced Ejection Fraction

Netherlands
Erasmus Medical Center

Active, not recruiting

Statistical Analysis Plan for the SANO-trial: Neoadjuvant Chemoradiotherapy Followed by Surgery Versus Active Surveillance for Oesophageal Cancer (SANO)

Esophageal Cancer | Surgical Oncology | Neoadjuvant Chemoradiotherapy | Active Surveillance

Netherlands
Marco J. Bruno
Boston Scientific Corporation

Recruiting

Prevalence of Multidrug Resistant Micro-organism Carriage in Patients Undergoing an ERCP in Four Different Countries (PREVENT)

Cholangiopancreatography, Endoscopic Retrograde | Drug Resistance, Multiple, Bacterial

United States, India, Netherlands, Italy
Radboud University Medical Center

Completed

Sunitinib and Atrial Trabeculae Contractility (SCAR)

Ischemia | Heart Failure | Cardiotoxicity

Netherlands
UMC Utrecht

Completed

IMPACT: Safety and Feasibility of a Single-stage Procedure for Focal Cartilage Lesions of the Knee. (IMPACT)

Inflammation | Knee Pain Swelling | Foreign-Body Reaction | Effusion (L) Knee

Netherlands
Maastricht University Medical Center

Recruiting

Empagliflozin for Peripheral Microvascular Dysfunction in Heart Failure With Preserved Ejection Fraction

Heart Failure With Preserved Ejection Fraction | Microvascular Dysfunction

Netherlands
Radboud University Medical Center
UMC Utrecht

Active, not recruiting

Long Term Effects of BCG Vaccination on Infectious and Immune Mediated Diseases (BCG-LT)

Infections | COVID-19 | Inflammation | BCG Vaccination Reaction

Netherlands
Amsterdam UMC, location VUmc

Enrolling by invitation

Evaluation of GeranylGeranylAcetone in Heart Failure With Preserved Ejection Fraction (GLADIATOR)

Heart Failure With Preserved Ejection Fraction

Netherlands
University of Aarhus
Odense University Hospital; Aarhus University Hospital; Rigshospitalet, Denmark; Hvidovre University Hospital and other collaborators

Completed

Continued Versus Discontinued Oxytocin Stimulation of Labour (CONDISOX)

Adverse Reaction to Oxytocin

Denmark, Netherlands
Behavioural Science Institute
Pluryn

Recruiting

Effectiveness of Take it Personal!

Alcohol Use | Drug Use | Adolescent Behavior | Personality | Mild Intellectual Disability, IQ 50-70 | Borderline Intellectual Disabilities (Intelligence Quotient 70-85)

Netherlands

Clinical Trials on Drug Action Increased in Netherlands

Sponsors and Collaborators

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