Clinical Trials on Drug Overdose

Total 3176 results

University of Cincinnati

Completed

AWAITS: A Web-based E-health Application for Active Illicit Opioid Users (AWAITS)

Substance Use Disorders | Overdose | Opioid-use Disorder | Drug Addiction | IV Drug Usage

United States
Yale University
National Institute on Drug Abuse (NIDA); National Drug Abuse Treatment Clinical...

Completed

Patient Reported Outcomes for Opioid Use Disorder

Patient Participation | Opioid-use Disorder | Overdose of Opiate

United States
Kaiser Permanente
Henry Ford Health System

Active, not recruiting

Health Insurance Instability and Mortality Among Patients Receiving Bup Tx for OUD

Death | Opioid Use Disorder | Opioid Overdose

United States
University of New Mexico
Kaleo Inc.

Completed

Naloxone Auto-injector as a Universal Precaution for Patients With Opioid Substance Use Disorder

Opioid-Related Disorders | Opiate Antagonist Overdose

United States
Hennepin Healthcare Research Institute

Completed

Monitoring of Overdose Patients With and Without Supplemental Oxygen in the Emergency Department

Overdose

United States
University of Pennsylvania
Public Health Management Corporation; Philadelphia Department of Public Health and other collaborators

Completed

Rapid Initiation of Drug Treatment Engagement (RIDE)

Overdose | Opioid-use Disorder

United States
State University of New York - Upstate Medical...

Completed

A Usability Assessment of Naloxone by Community Members

Drug Overdose
Norwegian University of Science and Technology
St. Olavs Hospital; University of Iceland

Completed

A Pilot Study of the Bioavailability of Nasal Naloxone

Drug Overdose

Norway
VA Eastern Colorado Health Care System
United States Department of Defense

Completed

Blister Packaging Medication to Increase Treatment Adherence and Clinical Response (BP)

Suicide, Attempted | Medication Adherence | Accidental Overdose | Deliberate Overdose

United States
Chestnut Health Systems
National Institute on Drug Abuse (NIDA)

Active, not recruiting

Recovery Initiation and Management After Overdose (RIMO) Experiment (RIMO)

Opioid-use Disorder

United States
RTM Vital Signs, LLC
Thomas Jefferson University

Unknown

Development of an Algorithm That Predicts Hypoventilation Due to an Opioid Overdose

Opioid-Related Disorders | Drug Overdose

United States
Tanta University

Completed

Ultrasound-guided PENG Block in Total Hip Replacement

Pain, Postoperative | Opioid Overdose

Egypt
Osakidetza

Completed

Effectiveness of a Postal Intervention to Improve the Use of PPI

Drug Overdose

Spain
University of Michigan
U.S. National Science Foundation

Recruiting

Removing Barriers: Community Partnering for Innovative Solutions to the Opioid Crisis (RB)

Opioid Use Disorder | Alcohol Use Disorder | Health Risk Behaviors | Criminal Behavior | Overdose of Opiate | Housing Problems

United States
Thomas Jefferson University
National Institute on Drug Abuse (NIDA); RTM Vital Signs, LLC

Completed

Development of a Tracheal Sound Sensor

Respiratory Insufficiency | Hypoventilation | Opioid Overdose

United States
Norwegian University of Science and Technology
St. Olavs Hospital

Completed

Pharmacokinetics and Pharmacodynamics of a New Formulation of Nasal Naloxone for Prehospital Use (OPI-14-001)

Drug Overdose

Norway
The University of Texas Health Science Center,...

Recruiting

Young Houston Emergency Opioid Engagement System (YHEROES)

Substance Use Disorders | Opioid Dependence | Opioid Use | Opioid-use Disorder | Opioid Overdose

United States
Drexel University

Completed

Addressing Overdose Risk Among Recently Incarcerated People Living With HIV/AIDS

Drug Overdose Accidental

United States
Norwegian University of Science and Technology
St. Olavs Hospital

Completed

Pharmacodynamics and Arteriovenous Differences of Naloxone in Healthy Participants Exposed to an Opioid (OPI-15-001)

Drug Overdose

Norway
Carilion Clinic
Virginia Polytechnic Institute and State University

Not yet recruiting

Naloxone Education in Total Joint Patients

Surgery | Opioid Use | Pain, Musculoskeletal | Overdose of Opiate

United States
Norwegian University of Science and Technology
St. Olavs Hospital

Completed

Bioavailability of a New Formulation of Nasal Naloxone for Prehospital Use

Drug Overdose

Norway
University of Massachusetts, Worcester
National Institute on Aging (NIA); University of Utah; Boston College

Active, not recruiting

Standardized Patient-Centered Medication Review in Home Hospice (SPECTORx)

Palliative Care | Interdisciplinary Communication | Caregivers | Deprescriptions | Hospices | Poly Pharmacy | Prescription Drug Overuse

United States
H. Lundbeck A/S

Recruiting

A Study of Eptinezumab in Participants With Migraine and Medication Overuse Headache

Migraine | Medication Overuse Headache

Spain, Italy, United States, Denmark, France, Netherlands, Australia, Georgia, Germany, Norway, Sweden
University of California, San Francisco

Not yet recruiting

Naloxone for Opioid Associated Out of Hospital Cardiac Arrest (NOPACA)

Heart Arrest, Out-Of-Hospital | Naloxone | Opioid Overdose

United States
Norwegian University of Science and Technology
St. Olavs Hospital; Smerud Medical Research International AS; A/S Den norske...

Completed

Bioavailability of Nasal Naloxone and Injected Naloxone Compared (OPI-15-002)

Drug Overdose

Norway
Amgen

Completed

A Study to Evaluate the Efficacy and Safety of Erenumab in Adults With Medication Overuse Headache

Migraine Headache

United States, Austria, Australia, Czechia, Finland, France, Hungary, Italy, Poland, Portugal, Spain, United Kingdom
San Francisco Department of Public Health

Completed

Repeated-dose Brief Intervention to Reduce Overdose and Risk Behaviors Among Naloxone Recipients (REBOOT)

Opioid-Related Disorders | Drug Overdose

United States
King's College London

Unknown

Buccal Versus Injectable Naloxone: a Phase I Healthy Volunteer Study

Opioid-Related Disorders | Drug Overdose
National Institute on Drug Abuse (NIDA)
Vince & Associates Clinical Research, Inc.

Completed

Pharmacokinetic Evaluation of Intranasal and Intramuscular Naloxone in Healthy Volunteers

Opioid-Related Disorders | Drug Overdose

United States
University of Michigan

Completed

Safety and Health Intervention Project (SHIP)

Drug Overdose | Opioid Related Disorders

United States
University of Michigan
Centers for Disease Control and Prevention

Completed

Safety & Prevention Outcomes Study (SPOS)

Opioid-Related Disorders | Drug Overdose

United States
University of Campinas, Brazil
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Topical Formulations of Liposomal Local Anesthetics

Administration, Topical | Administration, Topical Drug | Anesthetic Drugs

Brazil
Baystate Medical Center
National Institute on Drug Abuse (NIDA); The Miriam Hospital; Boston Medical... and other collaborators

Completed

Prescribe to Save Lives (PTSL)

Opioid-Related Disorders | Drug Overdose

United States
First Affiliated Hospital Xi'an Jiaotong University

Not yet recruiting

Remimazolam Improves the Safety in Elderly Patients Undergoing Gastrointestinal Endoscopy

Recovery | Drug Effect | Safety | Psychotropic Drugs | Anesthetics, Intravenous | Anesthetics

China
University of Wisconsin, Madison
National Institute on Drug Abuse (NIDA)

Completed

Smartphone Intervention for Overdose and COVID-19

COVID-19 | Substance Use Disorders | Overdose

United States
Hospices Civils de Lyon

Recruiting

25OH Vitamin D Overdoses and Risk of Bronchopulmonary Dysplasia or Death (25OHVDORBPDD)

Bronchopulmonary Dysplasia | Vitamin D Overdose

France
University of California, San Francisco

Completed

Pupillary Unrest in Ambient Light, and Relationship to Opioid-Induced Respiratory Depression

Acute Pain | Safety Issues | Respiratory Depression | Overdose of Opiate | Opioid; Intoxication, Perception Disturbance (Acute)

United States
Johns Hopkins Bloomberg School of Public Health
National Institute on Drug Abuse (NIDA)

Recruiting

A Setting Focus Overdose Prevention Intervention (Oasis)

HIV Infections | Drug Overdose | HCV

United States
Cari Health Inc.
Samplimy Medical AB

Recruiting

Assessment of Methadone Dose Taken Using Electrochemistry

Pain, Chronic | Metabolism Medication Toxicity | Methadone Toxicity | Methadone Overdose | Drug Metabolism, Poor, CYP2D6-Related

United States
Albert Einstein College of Medicine

Completed

Studies of Sulfur Metabolism in Humans

Metabolic Side Effects of Drugs

United States
Caroline Michaela Kistorp
Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark; Copenhagen... and other collaborators

Recruiting

Prospective, Longitudinal Study on FItness DOping in DenmarK (FIDO-DK/RH)

Infertility | Mental Health Issue | Fitness | Cardiovascular Complication | Anabolic Steroid Overdose | Illicit Drug Use

Denmark
Massachusetts General Hospital
Brigham and Women's Hospital

Active, not recruiting

EEG Monitoring in the Emergency Department

Substance Abuse | Drug Overdose | Alcohol Abuse

United States
April M Young
National Institute on Drug Abuse (NIDA)

Active, not recruiting

Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk

Sexually Transmitted Diseases | Opioid-Related Disorders | Substance Abuse | Drug Overdose | Opiate Substitution Treatment | Human Immunodeficiency Virus (HIV) | Hepatitis C (HCV) | Intravenous Drug Usage

United States
April M Young
National Institute on Drug Abuse (NIDA); Emory University; Centers for Disease... and other collaborators

Completed

Kentucky Communities and Researchers Engaging to Halt the Opioid Epidemic (CARE2HOPE)

HIV Infections | Substance Use | Opioid Use | HCV Infection | Sexually Transmitted Infections (Not HIV or Hepatitis) | Overdose, Drug

United States
University of Copenhagen
Carlsberg Foundation

Completed

Metabolic Imprints of Alcoholic Beverages (MetAl)

Metabolic Side Effects of Drugs and Substances

Denmark
Glostrup University Hospital, Copenhagen

Completed

Pupillary Response After Glaucoma Medication (pupil)

Drug Effect (Glaucoma Drugs)

Denmark
Fondation Lenval

Completed

Pharmacogenetics Anomaly Research in Children and Adolescents With Pharmacological Resistance to Psychotropic Drugs (M4P)

Psychotropic Drugs | Drug Resistance

France
University of Pecs
Dr. Szőke Henrik és Társa Egészségügyi Szolgáltató Kft.; Hungarian Medical... and other collaborators

Enrolling by invitation

LázBarát™ (FeverFriend™) Projekt: Attitude Toward Fever and Its Change in the Healthcare System

Virus Diseases | Bacterial Infections | Anxiety | Fever | Help-Seeking Behavior | Overdose of Analgesic Drug

Hungary
Clinical Hospital Centre Zagreb
Croatian Science Foundation; University of Zagreb School of Medicine

Recruiting

Pharmacogenomics in Prediction of Cardiovascular Drugs Adverse Reaction

Drug-Related Side Effects and Adverse Reactions | Pharmacogenetics | Cardiovascular Drugs

Croatia
NHS Lothian

Completed

The Markers and Paracetamol Poisoning Study 2 (MAPP2)

Paracetamol Overdose

United Kingdom

Clinical Trials on Drug Overdose

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CROs in Thailand

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