Clinical Trials on Drug Safety and Bioavailability in Germany

Total 100 results

Bayer

Completed

Pharmacy Based Pharmacoepidemiological Observational Study With Aspirin Protect 100 mg

Aspirin | Drug Safety | Effects, Longterm

Germany
Maastricht University
European Commission

Completed

Possible Effects of Propylthiouracil, Riociguat and Perphenazine on Circulation of Healthy Volunteers (REPO-STROKE1)

Safety Issues | Drug Drug Interaction

Germany
InflaRx GmbH

Completed

Clinical Assessment of Safety and Tolerability of the New Monoclonal Humanized Antibody CaCP29

Drug Safety

Germany
AstraZeneca

Completed

A Bioavailability Study With Alternate Methods of Administration of Naloxegol Tablets, and Solution

Healthy Subjects | Bioavailability

Germany
Patrys Ltd.

Completed

Safety and Preliminary Efficacy Study of the Antibody PAT-SM6 in Patients With Relapsed or Refractory Multiple Myeloma

Drug Safety

Germany
Biotronik SE & Co. KG

Completed

Lumax 740 Master Study (Lumax 740)

Safety and Efficacy of the Lumax 740 ICD Family

Germany
CannaXan GmbH

Completed

Clinical Trial on Pharmacokinetic and Tolerability of AP701

Tolerability | Safety | Pharmacokinetic

Germany
University Hospital Carl Gustav Carus

Completed

Automated Early Warning Scoring on Surgical Normal Wards

Emergencies | Safety Issues

Germany
CannaXan GmbH

Completed

Clinical Trial on Pharmacokinetics and Tolerability of AP707

Pharmacokinetics | Tolerability | Safety

Germany
Zealand Pharma
Profil Institut für Stoffwechselforschung GmbH

Recruiting

A Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP7570

Safety and Tolerability

Germany
Evangelisches Krankenhaus Düsseldorf
Olympus

Completed

Motorized Spiral Colonoscopy Trial: A First Feasibility Trial (MSCT)

Adenoma | Colonoscopy | Safety Issues

Germany
Johann Wolfgang Goethe University Hospital
CSL Behring; B. Braun Melsungen AG; Vifor Pharma; Fresenius Kabi

Recruiting

The German Patient Blood Management Network

Clinical Safety of a PBM Program

Germany
RWTH Aachen University
Ärztliche Zentrum für Qualität in der Medizin; Universitätsklinikum Bonn -...

Completed

Medication Reconciliation in Comparison to an Extensive Medication Safety Check

Elderly | Adverse Drug Event

Germany
RWTH Aachen University

Completed

Operation of a Mobile Telemedicine System in the EMS

Safety | Teleconsultation | Prehospital Emergency

Germany
Dr. Florian Piekarski

Completed

Audit of International Intraoperative Hemotherapy and Blood Loss Documentation

Patient Safety | Patient Blood Management

Germany
Dr. Frank Behrens
Bionorica SE

Active, not recruiting

Impact of Silymarin Dosages to Decrease Drug-induced Elevated Liver Enzymes Compared to Placebo (SILVER)

Drug-induced Liver Injury

Germany
Heinrich-Heine University, Duesseldorf

Terminated

The Effect of Topical Brimonidine Tartrate on Hand-foot Syndrome (HFS) in Cancer Patients (BRIMOCAN)

Hand-foot Syndrome

Germany
Jens Bräunlich, MD

Completed

NHF in Acute Hypercapnic Acute Exacerbation of COPD

Safety of NHF in Acute Hypercapnic AECOPD

Germany
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Compare Capsule and Tablet Forms of MDV3100 (Enzalutamide) After Administration of a Single Set Dose Under Fasted Conditions in Healthy Male Subjects

Healthy Subjects | Relative Bioavailability | Castration Resistant Prostate Cancer (CRPC) | MDV3100

Germany
Bayer

Completed

Sorafenib Drug Drug Interaction Study in Healthy Male Subjects

Drug Interactions

Germany
Sensimed AG

Completed

SENSIMED Triggerfish Discomfort During IOP Monitoring (09/02)

Safety and Tolerability of SENSIMED Triggerfish in Glaucoma Patients

Germany
Ferring Pharmaceuticals

Recruiting

NOCDURNA PASS Study Using Registries in Denmark, Germany and Sweden

Adverse Drug Event

Germany
University Hospital Tuebingen
Robert Bosch Gesellschaft für Medizinische Forschung mbH

Completed

Ice Plant Intensive Cream for the Prevention of Hand-Foot Syndrome in Breast Cancer: Pilot Randomized Controlled Trial (WIn-HFS)

Breast Cancer | Hand-Foot Syndrome

Germany
Jena University Hospital

Completed

Non-Inferiority Study to Compare the Effectiveness of the Seldinger Over-the-Wire Technique and the Modified Seldinger Technique (Over-the-Wire)

Effectiveness and Safety of the Seldinger Wire Technique Using a 145 cm Guidewire With the Modified Seldinger Technique Using a 70 cm Guidewire

Germany
Bayer

Completed

Drug-drug Interaction Study Using Rosuvastatin as a Breast Cancer Resistant Protein (Efflux Transporter), Organic Anion-transporting Polypeptide (OATP)1B1, and OATP1B3 (Uptake Transporters) Probe Substrate

Healthy Volunteers | Pharmacokinetics | Drug Interaction

Germany
LTS Lohmann Therapie-Systeme AG

Completed

Magnetic Marker Monitoring of Furosemide-containing Gastroretentive Formulation in Healthy Male Subjects (Fasting and Fed Conditions)

Gastroretentive Drug Formulation of Furosemide | Oedema

Germany
Universitätsklinikum Hamburg-Eppendorf

Completed

Pharmacokinetic of Posaconazole in Critically Ill Patients

Critical Illness | Therapeutic Drug Monitoring

Germany
Andreas Benesic, MD
MetaHeps GmbH

Unknown

Cells of Monocytic Origin as Surrogate Markers for Individual Drug Effects and Hepatotoxicity

Adverse Reaction to Drug | Drug-induced Disorder of Liver

Hong Kong, Australia, Germany, Japan, Korea, Republic of
Pierre Fabre Medicament

Completed

Exploratory Study in the Relief of Drug-induced Xerostomia Associated With Hyposialia

Drug-induced Xerostomia

Germany
AstraZeneca

Completed

A Single Ascending Dose Study To Assess The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of AZD9567.

Rheumatoid Arthritis | Healthy Subjects | Pharmacokinetics | Pharmacodynamics | Tolerability | Safety

Germany
Biotronik SE & Co. KG

Completed

ProMRI PROVEN Master Study

Safety of MR (Magnetic Resonance) Conditional CRT-pacemakers and ICDs

France, Germany, Hungary, Canada, Australia, Austria, Czech Republic, Switzerland
University Medicine Greifswald

Completed

Pharmacokinetic Drug Interaction Between Ezetimibe and Sirolimus After Single Dose Administration in Healthy Subjects

Hypercholesterolemia | Pharmacokinetics | Immunosuppression | Drug Interactions

Germany
University Medicine Greifswald

Completed

Pharmacokinetic Drug Interaction Between Ezetimibe and Tacrolimus After Single Dose Administration in Healthy Subjects

Hypercholesterolemia | Pharmacokinetics | Immunosuppression | Drug Interactions

Germany
University Hospital Schleswig-Holstein

Recruiting

Evaluation of Safety and Pharmacokinetics of Oral Controlled-ileal-release Nicotinic Acid (CIR-NA) Compared to Immediate-release Nicotinic Acid and Placebo in Healthy Subjects and Subjects With Prediabetes

Safety Issues | Pharmacokinetic

Germany
Universitätsklinikum Hamburg-Eppendorf

Completed

Adequacy of Perioperative Cefuroxime Dosage According to the BMI

Obesity; Drug

Germany
AIO-Studien-gGmbH

No longer available

A Randomized, Open-label Phase III Trial of Mapisal® Versus an Urea Hand-foot Cream as Prophylaxis for Capecitabine-induced Hand-foot Syndrome in Patients With Gastrointestinal Tumors or Breast Cancer (PROCAPP)

the Treatment Hand-foot Syndrome Patients With Gastrointestinal Tumors or Breast Cancer, Who Are Treated With Capecitabine

Germany
Charite University, Berlin, Germany
Eli Lilly and Company

Withdrawn

Optimal Duration of Olanzapine Add-on Therapy in Major Depression (OLA-D)

Relapse Rate of a Major Depressive Episode | Safety of Olanzapine in Subjects With Major Depression

Germany
University Hospital Marburg

Recruiting

IF-MCT 16:8: Investigating the Influence of Intermittent Fasting With and Without MCTs in Patients With Drug-resistant Epilepsy (IF-MCT16:8)

Epilepsy | Intermittent Fasting

Germany
RWTH Aachen University

Terminated

Xenon and Therapeutical Hypothermia After Successful Cardiopulmonary Resuscitation (10-015)

Efficacy and Safety of Xenon Inhalation | Successful Cardiopulmonary Resuscitation | Addition to Therapeutical Hypothermia

Germany
Endologix

Active, not recruiting

Nellix® Registry Study: EVAS-Global (EVAS-FORWARD 1)

Safety and Performance of the Nellix Endovascular Sealing System

Germany, Latvia, Luxembourg, Netherlands, New Zealand, Norway, Sweden, United Kingdom
University of Heidelberg Medical Center

Completed

Neural Correlates of Sensory Specific Satiety (Gusto)

Obesity | Satiety Response | Functional Neuroimaging

Germany
Nutricia Research

Active, not recruiting

Renoir: A Randomised, Double-blind, Controlled Trial to Evaluate the Effects of a New Human Milk Fortifier on Growth and Tolerance in Preterm Infants. (Renoir)

Growth | Tolerance | Safety | Subjects in Need of a Human Milk Fortifier (HMF)

Netherlands, France, Germany, United Kingdom
Impulse Dynamics

Recruiting

Optimizer System With ODOCOR II CCM™ Leads

Evaluate the Safety and Useability of the ODOCOR II Intra-cardiac Lead

Spain, Germany, Italy
Foundation for Innovative New Diagnostics, Switzerland

Completed

Evaluation of Centralised TB Assay Solutions

Tuberculosis | Drug-resistant Tuberculosis

Georgia, Germany, India, Moldova, Republic of, South Africa
Matthias Schwab

Terminated

Pharmacogenetic Factors and Side Effects of Metoclopramide and Diphenhydramine (MalD)

Drug Metabolism, Poor, CYP2D6-RELATED

Germany
Air Liquide Santé International
Orion Corporation, Orion Pharma

Completed

Xenon Compared to Sevoflurane and Total Intravenous Anaesthesia for Coronary Artery Bypass Graft Surgery

Coronary Artery Disease | Coronary Artery Bypass Graft Surgery | General Anesthetic Drug Allergy

France, Italy, Germany, Netherlands
AstraZeneca

Completed

A Multiple Dosing (14 Days) Study to Assess Efficacy and Safety of Three Dose Levels of AZD7594, Given Once Daily by Inhalation, in Patients With Mild to Moderate Asthma

Asthma | Efficacy | Safety

Germany, Bulgaria
Johann Wolfgang Goethe University Hospital
Stryker Neurovascular

Completed

Simulation-based Training of Rapid Evaluation and Management for Acute Stroke (STREAM) Trial (STREAM)

Stroke, Thrombolysis, Thrombectomy, Simulation Training, Patient Safety

Germany
Heidelberg University
University Hospital, Essen

Completed

Comparison Between Inhalation and Intravenous Induction of Anaesthesia During Interventional Mitral Valve Repair (COMPETENT)

Blood Pressure | Hypotension Drug-Induced

Germany
University Heart Center Freiburg - Bad Krozingen

Unknown

Effect of Clopidogrel Loading and Risk of PCI (EXCELSIOR)

Coronary Artery Disease | Drug Resistance

Germany

Clinical Trials on Drug Safety and Bioavailability in Germany

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