Clinical Trials on Drug Toxicity in Australia

Total 66 results

GenFleet Therapeutics (Australia) Pty Ltd.

Completed

A Study of GFH312 in Healthy Subjects

Healthy | Toxicity

Australia
Medical University of Graz

Completed

The Influence of Tramadol on Platelet Function

Drug Toxicity | Platelet Dysfunction | Clotting Disorder

Austria
University Health Network, Toronto
University College London Hospitals; Brigham and Women's Hospital; University... and other collaborators

Recruiting

The STOP-MED CTRCD Trial (STOP-MED)

Heart Failure | Cancer | Cardiotoxicity | Cardiac Toxicity | Antineoplastics Toxicity

Canada, United States, United Kingdom, Australia
Daewoong Pharmaceutical Co. LTD.

Completed

Pharmacokinetic Interaction Between DWP14012 and DWC202005 in Healthy Volunteers

Drug-drug Interaction

Australia
Otsuka Pharmaceutical Development & Commercialization...

Completed

A Phase 1, Drug Interaction Study Between AVP-786 and Paroxetine and Between AVP-786 and Duloxetine in Healthy Subjects

Drug-drug Interaction

Australia
Blade Therapeutics

Completed

Drug-Drug Interaction (DDI) Study in Healthy Volunteers

Drug Drug Interaction

Australia
Australian National University
University of Peradeniya; Department of Foregin Affairs and Trade, Australia

Completed

Family Violence and Alcohol and Drug Misuse in Sri Lanka

Intimate Partner Violence | Domestic Abuse | Drug and Alcohol Abuse

Australia
HUYABIO International, LLC.

Completed

Drug-Drug Interaction Study of HBI-3000 and Paroxetine in Healthy Adult Male and Female Subjects

Drug-drug Interaction

United States, Australia
Calithera Biosciences, Inc
Novotech (Australia) Pty Limited

Completed

Impact of a Histamine H2 Receptor Antagonist (H2RA) on the Pharmacokinetics (PK) of Telaglenastat in Healthy Subjects

Drug Interaction

Australia
Murdoch Childrens Research Institute

Recruiting

Minimising Adverse Drug Reactions and Verifying Economic Legitimacy in Children (MARVEL-PIC) (MARVEL-PIC)

Neoplasms | Bone Marrow Transplantation

Australia
Medical University Innsbruck

Recruiting

Cryotherapy vs. Cryocompression for Preventing Chemotherapy-induced-peripheral-neuropathy in Women Undergoing Chemotherapy

Chemotherapeutic Toxicity | Chemotherapy-induced Peripheral Neuropathy | Chemotherapeutic Agent Toxicity

Austria
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Amifostine in Treating Children With Malignant Germ Cell Tumors

Ovarian Cancer | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor | Drug/Agent Toxicity by Tissue/Organ

United States, Canada, Netherlands, Puerto Rico, Switzerland, Australia
The Alfred
National Health and Medical Research Council, Australia; Monash University

Withdrawn

Predictors of Drug Hypersensitivity in HIV Infected Subjects

HIV Infections | Hypersensitivity

Australia
Premier Specialists, Australia
Steritas

Active, not recruiting

Investigating the Morbidity of Glucocorticoid Use in Patients With Autoimmune Bullous Diseases (AIBDs)

Glucocorticoids Toxicity | Autoimmune Bullous Dermatosis

Australia
Gebro Pharma GmbH

Completed

S(+)-Ibuprofen Effects on Asprin Treated Volunteers

Drug Interactions

Austria
SignPath Pharma, Inc.

Completed

Evaluation of Liposomal Curcumin in Healthy Volunteers

Drug Safety

Austria
Affiris AG

Completed

Safety, Immunogenicity and Dose Response of ATH03, a New Vaccine Against the Cholesterol Ester Transfer Protein (CETP)

HDL | Drug Safety

Austria
Prof. Peter Gerner, M.D.

Completed

Efficacy and Safety Study of Dexmedetomidine as an Additive to Local Anesthetics in Shoulder Surgery

Self Efficacy | Drug Safety

Austria
Andreas Benesic, MD
MetaHeps GmbH

Unknown

Cells of Monocytic Origin as Surrogate Markers for Individual Drug Effects and Hepatotoxicity

Adverse Reaction to Drug | Drug-induced Disorder of Liver

Hong Kong, Australia, Germany, Japan, Korea, Republic of
J.J.Swen
Karolinska Institutet; Medical University of Vienna; Uppsala University; St. Antonius... and other collaborators

Completed

PREemptive Pharmacogenomic Testing for Preventing Adverse Drug REactions (PREPARE)

Adverse Drug Reaction

Austria, Netherlands, Italy, Greece, Slovenia, Spain, United Kingdom
Macfarlane Burnet Institute for Medical Research...
St Vincent's Hospital Melbourne

Unknown

The TAP Study: Treating People Who Inject Drugs in Community-Based Settings Using a Social Network Approach (TAP)

Hepatitis C | Drug Abuse, Intravenous

Australia
Indivior Inc.

Completed

Acceptability and Safety of Switching From Subutex or Other Opioid Drug Dependence Therapy to Suboxone (NIS P05444)

Opioid-Related Disorders | Drug Abuse | Opiate Dependence

Austria
ES Therapeutics Australia Pty Ltd

Recruiting

Efficacy, Safety and Pharmacokinetics of ES-481 in Adult Patients With Drug Resistant Epilepsy

Drug Resistant Epilepsy

Australia
Paracelsus Medical University
Heinrich-Heine University, Duesseldorf; Poznan University of Medical Sciences; University Hospital of Ferrara and other collaborators

Completed

Intra-Operative Electron Boost and Hypofractionated Whole-Breast Irradiation During Breast-conserving Treatment (BCT) (HIOB)

Toxicity | Local Neoplasm Recurrence

Austria
Genovate-NaviFUS (Australia) Pty Ltd.
Genovate Biotechnology Co., Ltd.,; NaviFUS Corporation

Recruiting

Evaluation of the NaviFUS System in Drug Resistant Epilepsy

Drug Resistant Epilepsy | Epilepsy, Temporal Lobe

Australia
Flinders University
Flinders Medical Centre; Lyell McEwin Hospital

Recruiting

Assessment of Myocardial Injury in Patients Treated With Immune Checkpoint Inhibitors (MIICI)

Myocardial Injury | Myocarditis | Cardiotoxicity | Immune Checkpoint Inhibitors

Australia
Children's Oncology Group
National Cancer Institute (NCI); Children's Cancer Group

Completed

Chemotherapy Followed by Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin's Disease

Lymphoma | Cardiac Toxicity

United States, Australia, Canada
Medical University of Graz

Recruiting

Pre-op Fluid Study

Anesthesia | Hypotension Drug-Induced

Austria
Medical University of Graz

Recruiting

Fetal Haemoglobin and Cerebral and Peripheral Oxygenation. (HbFIN)

Preterm Birth | Oxygen Toxicity | Fetal Hemoglobin

Austria
The University of Queensland
University of California, Los Angeles; Monash University; University of Sydney; Griffith University and other collaborators

Active, not recruiting

Gonorrhoea Resistance Assessment by Nucleic Acid Detection (GRANDII) (GRANDII)

Gonorrhea | Antimicrobial Stewardship | Drug Resistance, Microbial

Australia
Wilhelminenspital Vienna
Akron Molecules AG

Completed

Analgesic Effects of Midazolam in Human Volunteers (GabA01)

Analgesic Drugs | Antinociceptive Agents

Austria
Medical University of Vienna

Completed

Heavy Metals, Angiogenesis Factors and Osteopontin in Coronary Artery Disease (CAD)

Coronary Artery Disease | Ischemic Heart Disease | Heavy Metal Toxicity

Austria
Medical University of Vienna

Completed

Drug Drug Interactions of Aspirin and P2Y12-inhibitors

Myocardial Infarction | Drug Interaction Potentiation

Austria
Duke University
Christian Doppler University Hospital

Enrolling by invitation

5-SENSE Score Validation Study

Epilepsy Intractable

United States, Spain, Australia, Austria, Canada, Czechia, Denmark, France, Germany, Japan, Romania, Switzerland
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Dexrazoxane in Treating Patients With Newly Diagnosed Nonmetastatic Osteosarcoma

Sarcoma | Cardiac Toxicity

United States, Canada, Netherlands, Puerto Rico, Switzerland, Australia
Cerebral Therapeutics LLC

Terminated

Study to Assess Intracerebroventricular (ICV) Delivery of CT-010 in Subjects With Focal Seizures, With Temporal Lobe Onset With or Without Secondary Generalization

Refractory Epilepsy

Israel, Australia
Royal Prince Alfred Hospital, Sydney, Australia

Completed

Cardiotoxicity of Adjuvant Trastuzumab (CATS)

Heart Failure | Breast Neoplasms

Australia
Decibel Therapeutics

Completed

Study to Evaluate Safety and Efficacy of DB-020 to Protect Hearing in Patients Receiving Cisplatin for Cancer Treatment

Ototoxicity

United States, Australia
Medical University Innsbruck

Unknown

Ropivacaine 0,2% Plus Dexamethasone Versus Ropivacaine 0,2% Plus Placebo in Modified Pectoral Block

Anesthesia, Local | Effect of Drugs | Breast Pain

Austria
LivaNova

Active, not recruiting

Registry of Subjects With Drug Resistant Epilepsy and Treated With the VNS Therapy System. (CORE-VNS)

Epilepsy | Seizures | Drug Resistant Epilepsy

Australia, Italy, United States, Israel, United Kingdom, Canada, Brazil, Japan, Belgium, India, Austria, China, Netherlands, Poland, Portugal, Saudi Arabia
Marinus Pharmaceuticals

Completed

Phase 3 Study of Adjunctive Ganaxolone in Adults With Drug-resistant Partial Onset Seizures and Open-label Extension

Drug Resistant Partial Onset Seizure

United States, Australia, Russian Federation, Bulgaria, Germany, Poland
UCB Biopharma S.P.R.L.

Completed

Study to Test the Efficacy and Safety of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adults With Drug-resistant Epilepsy (ARISE)

Focal-Onset Seizures | Drug-resistant Epilepsy

United States, Australia, Belgium, Bulgaria, Canada, Czechia, France, Germany, Hungary, Italy, Japan, Lithuania, Mexico, Poland, Portugal, Slovakia, Spain, Turkey, United Kingdom
UCB Biopharma SRL

Terminated

A Study to Test the Efficacy and Safety of Padsevonil as Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy (DUET)

Drug-Resistant Epilepsy | Focal-Onset Seizures

United States, Australia, Belgium, Bosnia and Herzegovina, Bulgaria, Croatia, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Norway, Poland, Portugal, Romania, Serbia, Slovakia, Spain, Sweden, Switzerlan... and more
UCB Biopharma SRL

Terminated

Study to Test the Safety and Efficacy of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy

Drug-Resistant Epilepsy | Focal-Onset Seizures

United States, Australia, Belgium, Bosnia and Herzegovina, Bulgaria, Canada, Croatia, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Lithuania, Mexico, Poland, Romania, Serbia, Slovakia, Spain, Turk... and more
Amgen

Completed

A Study to Evaluate the Efficacy and Safety of Erenumab in Adults With Medication Overuse Headache

Migraine Headache

United States, Austria, Australia, Czechia, Finland, France, Hungary, Italy, Poland, Portugal, Spain, United Kingdom
MedtronicNeuro

Completed

Product Surveillance Registry- Deep Brain Stimulation for Epilepsy (MORE)

Refractory Epilepsy

Belgium, Sweden, Austria, United Kingdom, Poland, Germany, Portugal, Canada, Finland, Hungary, Italy, Netherlands, Russian Federation
Duke University
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Multi-Drug Resistant Organism Network (MDRO Network)

Bacterial Infections | Infections Resistant to Multiple Drugs

China, United States, Australia, Colombia
H. Lundbeck A/S

Recruiting

A Study of Eptinezumab in Participants With Migraine and Medication Overuse Headache

Migraine | Medication Overuse Headache

Spain, Italy, United States, Denmark, France, Netherlands, Australia, Georgia, Germany, Norway, Sweden
Kaiser Franz Josef Hospital

Withdrawn

The IDEAL-PCI Extended Registry (IDEAL-PCI ext)

Platelet Dysfunction Due to Drugs | Coronary Arterioscleroses

Austria
Sándor Beniczky
Hospital del Mar; Centro Hospitalar e Universitário de Coimbra, E.P.E.; Motol... and other collaborators

Active, not recruiting

Clinical Utility of Automated Electric Source Imaging in Presurgical Evaluation (PROMAESIS)

Surgery | Refractory Epilepsy | Electroencephalography | Brain Imaging

Spain, Portugal, Austria, Czechia, Denmark, Germany, Italy, Romania

Clinical Trials on Drug Toxicity in Australia

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