Clinical Trials on Drug Therapy

Total 5668 results

Albert Einstein College of Medicine
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Long Term Outcomes of Therapy in Women Initiated on Lifelong ART Because of Pregnancy in DR Congo (CQI-PMTCT)

HIV/AIDS | Antiretroviral Therapy | Pregnancy Outcomes | HIV-exposed Infants

Congo, The Democratic Republic of the
Centre Leon Berard
CREATIS Laboratory

Completed

Phase 2 Study Evaluating Mid-position Strategy in Radiotherapy Treatment for Patients With a Locally Advanced Non-small Cell Lung Carcinoma (midP)

Non-small Cell Lung Cancer | Radiation Therapy | Locally Advanced Disease | Non-metastatic Disease | Non-resectable Disease

France
University Hospital, Montpellier

Completed

Urinary Biomarkers for AKI Diagnosis in Patients With SARS-CoV-2 (COVID-19) (COVID-AKI)

COVID-19 | Acute Kidney Injury | Renal Replacement Therapy

France
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy With or Without Chemotherapy in Reducing Mouth Dryness in Patients With Nasopharyngeal Cancer

Head and Neck Cancer | Radiation Toxicity | Oral Complications of Radiation Therapy

United States
North Central Cancer Treatment Group
National Cancer Institute (NCI)

Completed

Mometasone Furoate in Preventing Radiation Dermatitis in Patients Undergoing Radiation Therapy to the Breast or Chest Wall for Invasive Breast Cancer or Ductal Carcinoma in Situ

Breast Cancer | Radiation Toxicity | Skin Reactions Secondary to Radiation Therapy | Dermatologic Complications

United States
Solvay Pharmaceuticals

Completed

Dronabinol Versus Placebo in Treatment and Prevention of Highly Active Anti-Retroviral Therapy (HAART)-Related Nausea and Vomiting

HIV Infections | Highly Active Antiretroviral Therapy (HAART)-Related Nausea and Vomiting

United States
Liaoning Tumor Hospital & Institute

Not yet recruiting

Early Blocking Strategy for Metachronous Liver Metastasis of Colorectal Cancer Based on Pre-hepatic CTC Detection

Preventive Effect of Quintuple Therapy on Metachronous Liver Metastases in Patients With Colorectal Cancer
Ashkan Eftekhari

Recruiting

Absolute Coronary Flow in Patients With Heart Failure With Reduced Ejection Fraction and Left Bundle Branch Block With Cardiac Resynchronization Therapy (FLOW-LBBB)

Heart Failure | Left Bundle-Branch Block | Dilated Cardiomyopathy | Cardiac Resynchronization Therapy

Denmark
RenJi Hospital

Recruiting

Preventive Effects of Aspirin as Adjuvant Therapy in Patients With Locally Advanced Renal Cell Carcinoma

Aspirin as Adjuvant Therapy in Patients With Surgically Treated High Risk Renal Cell Carcinoma

China
Brigham and Women's Hospital
The Fenway Institute

Active, not recruiting

Next Generation Ingestible Sensors for Medication Adherence Measurement (NextGen)

HIV Infection | Adherence, Medication | Antiretroviral Therapy | Adherence, Treatment | Pre-Exposure Prophylaxis

United States
University of Virginia

Active, not recruiting

Low Intensity Shockwave Therapy for Erectile Dysfunction

Erectile Dysfunction | Erectile Dysfunction Following Radical Prostatectomy | Erectile Dysfunction Following Radiation Therapy | Erectile Dysfunction Due to General Medical Condition | Erectile Dysfunction Due to Arterial Insufficiency

United States
David Williams

Active, not recruiting

Phase I/II Trial of Lentiviral Gene Transfer for SCID-X1 With Low Dose Targeted Busulfan Conditioning

Gene Therapy | Severe Combined Immunodeficiency, X Linked

United States, United Kingdom
Centro Hospitalar de Entre o Douro e Vouga

Active, not recruiting

Is the Ingestion of Jelly Associated With Delayed Gastric Emptying?

Surgery | Fasting | Ultrasound Therapy; Complications | Aspiration Pneumonia Due to Regurgitated Food

Portugal
University of Southern California
National Cancer Institute (NCI)

Active, not recruiting

Pevonedistat, Cytarabine, and Idarubicin in Treating Patients With Acute Myeloid Leukemia

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Therapy-Related Acute Myeloid Leukemia | Acute Myeloid Leukemia With Myelodysplasia-Related Changes

United States
University Ghent

Completed

Effectiveness of Speech Therapy in Trans Women.

Gender Dysphoria | Speech Therapy | Transgenderism | Voice Disorder Due to Transsexualism

Belgium
Cook MyoSite

Completed

An Investigation of the Safety of 4 Different Doses of Autologous Muscle Derived Cells as Therapy for Stress Urinary Incontinence

Stress Urinary Incontinence | Cell Therapy

United States, Canada
RenJi Hospital

Completed

Toripalimab Combined With Axitinib as Neoadjuvant Therapy in Patients With Non-metastatic Locally Advanced Nonmetastatic Clear Cell Renal Cell Carcinoma

Neoadjuvant Therapy of Non-metastatic Locally Advanced Renal Cell Carcinoma

China
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S1013: Validation of Cancer Questionnaire for Skin Toxicities in Patients With Colorectal Cancer or Lung Cancer Receiving Cetuximab, Panitumumab, or Erlotinib Hydrochloride

Colorectal Cancer | Lung Cancer | Dermatologic Complications | Therapy-related Toxicity

United States
RenJi Hospital

Unknown

Neoadjuvant PD-1 Monoclonal Antibody Plus Cisplatin-based Chemotherapy in Locally Advanced Upper Tract Urothelial Carcinoma

Neoadjuvant Therapy of Locally Advanced Upper Urinary Tract Urothelial Carcinoma

China
Universitair Ziekenhuis Brussel

Unknown

The Impact of CBT-i on CPAP Therapy Use and Drop Outs in OSAS Patients With Insomnia.

Insomnia | Obstructive Sleep Apnea | Cognitive Behavioral Therapy | Continuous Positive Airway Pressure

Belgium
University of Zurich

Withdrawn

Effect of Catheter-based Radiofrequency Ablation Therapy in Patient With Therapy-resistant Hypertension and Sleep Apnea Syndrome

Therapy-resistant Hypertension and Sleep Apnea

Switzerland
PENTA Foundation
Medical Research Council; ANRS, Emerging Infectious Diseases

Completed

KONCERT A Kaletra ONCE Daily Randomised Trial of the Pharmacokinetics, Safety and Efficacy of Twice-daily Versus Once-daily Lopinavir/Ritonavir Tablets Dosed by Weight as Part of Combination Antiretroviral Therapy in Human Immunodeficiency Virus-1 (HIV-1) Infected Children (PENTA 18) (KONCERT)

Antiretroviral Therapy in HIV-1 Infected Children

Netherlands, Germany, United Kingdom, Ireland, Thailand
Benha University

Recruiting

Effects of Systemic Drugs on Intraocular Pressure

Hypertension | Glaucoma, Angle-Closure | Glaucoma Suspect | Glaucoma Secondary to Drugs, Bilateral

Egypt
Yale University

Active, not recruiting

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Substudy III (THC-ETOH-III)

Cannabis | Alcohol Effect | Driving Under the Influence of Alcohol and Other Drugs

United States
Yale University

Active, not recruiting

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study II (THC-ETOH-II)

Cannabis | Alcohol Effect | Driving Under the Influence of Alcohol and Other Drugs

United States
Yale University

Active, not recruiting

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition (THC-ETOH)

Cannabis | Alcohol Effect | Driving Under the Influence of Alcohol and Other Drugs

United States
Catholic University of the Sacred Heart
University Hospital, Geneva; Universiteit Antwerpen; Clinical Centre of Serbia; Canisius-Wilhelmina Hospital and other collaborators

Unknown

SATURN 04 Nosocomial Acquisition Study (SATURN)

Infection Due to ESBL Bacteria | Bacterial Resistance | Infection Resistant to Multiple Drugs | Staph Aureus Methicillin Resistant Colonization

Italy, Romania, Serbia
Yale University

Active, not recruiting

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study I (THC-ETOH-I)

Cannabis | Alcohol Effect | Driving Under the Influence of Alcohol and Other Drugs

United States
Hasanuddin University
Chulalongkorn University

Completed

Artificial Inteligent for Diagnosing Drug-Resistant Tuberculosis

Resistance to Tuberculostatic Drugs | MDR Tuberculosis

Indonesia
Institut de cancérologie Strasbourg Europe

Not yet recruiting

Role of Sodium-glucose Linked Transporter 2 (SGLT2) and Its Inhibitor Over CARdiotoxicity Induced by Anthracyclines and Breast Cancer Tumorigenesis SCARA-B (SCARA-B)

Breast Neoplasms

France
Tanta University

Recruiting

Evaluation of Possible Safety and Efficacy of Fenofibrate in the Prophylaxis of Doxorubicin Induced Cardiotoxicity in Breast Cancer Patients

Breast Cancer Stage 2 and 3

Egypt
National Cheng-Kung University Hospital

Recruiting

Strategy Therapy on Cancer Therapy-Related Cardiac Dysfunction

Heart Failure | Lymphoma | Breast Cancer | Cardiotoxicity | Chemotherapeutic Toxicity

Taiwan
University Medical Center Groningen
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

Breast Cancer Long-term Outcomes on Cardiac Functioning: a Longitudinal Study (BLOC-II)

Heart Failure | Ventricular Dysfunction | Cardiotoxicity | Neoplasm, Breast

Netherlands
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer

Breast Carcinoma | Cardiotoxicity

United States
Baystate Medical Center
National Institute on Drug Abuse (NIDA); Tufts University; Dartmouth-Hitchcock... and other collaborators

Recruiting

Rural New England Health Study (Phase 2) (DISCERNNE)

Hepatitis C | Opioid Use Disorder | IV Drug Usage

United States
Odense University Hospital
Aarhus University Hospital; University of Copenhagen; Aalborg University Hospital

Recruiting

Imaging Versus Cardiac Biomarker Monitored HER2 Directed Therapy in Patients With Breast Cancer (HER2BIC)

HER2-positive Breast Cancer | Cardiotoxicity

Denmark
Moscow State University of Medicine and Dentistry

Recruiting

Observational Trial of Cardiotoxicity in Patients Undergoing Chemotherapy. (PROMETEY)

Heart Failure | Dilated Cardiomyopathy | Cardiotoxicity

Russian Federation
Memorial Sloan Kettering Cancer Center

Completed

Assessment for Long-Term Cardiovascular Impairment Associated With Trastuzumab Cardiotoxicity in HER2-Positive Breast Cancer Survivors

Trastuzumab Cardiotoxicity | HER2-Positive Breast Cancer Survivors

United States
Centre Hospitalier Universitaire Saint Pierre

Terminated

Intratympanic Administration of N-acetylcysteine for Protection of Cisplatin-induced Ototoxicity

Ototoxicity | Tinnitus | Ototoxic Hearing Loss | Ototoxic Hearing Loss, Bilateral

Belgium
Masaryk University

Active, not recruiting

Efficacy and Safety of TKIs' Withdrawal After a Two-step Dose Reduction in Patients With Chronic Myeloid Leukemia (HALF)

Chronic Myeloid Leukemia, Chronic Phase | Withdrawal;Drug

Czechia
Ipsen

Completed

An Efficacy and Safety Study of Somatuline Depot (Lanreotide) Injection to Treat Carcinoid Syndrome (ELECT)

Carcinoid Syndrome

United States, Turkey, Brazil, India, Ukraine, South Africa, Czechia, Latvia, Poland, Russian Federation, Serbia
Radboud University Medical Center

Unknown

Early Detection of Cardiac Damage With CMR in Women With Breast Cancer (EARLY-CATCH)

Breast Cancer | Cardiotoxicity | Chemotherapy Induced Systolic Dysfunction

Netherlands
Medical University of South Carolina
National Institute on Drug Abuse (NIDA)

Completed

Integrated Treatment of OEF/OIF Veterans With PTSD & Substance Use Disorders (COPE)

Alcohol Dependence | Posttraumatic Stress Disorders | Combat Disorders | Drug Dependence

United States
Vancouver Infectious Diseases Centre

Unknown

Switching to a Fixed Dose Combination of Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) in HIV-1 Infected Marginalized Populations Who Are Virologically Suppressed

Drug Use | Human Immunodeficiency Virus I Infection

Canada
Lexicon Pharmaceuticals

Completed

Telotristat Etiprate - Expanded Treatment for Patients With Carcinoid Syndrome Symptoms (TELEPATH)

Carcinoid Syndrome

United States, Australia, Belgium, Canada, France, Germany, Israel, Italy, Netherlands, Spain, Sweden, United Kingdom
Mansoura University

Completed

Trigonal vs Non Trigonal Botox Injection in OAB.

Quality of Life | Urologic Diseases | Overactive Bladder Syndrome | Anticholinergic Syndrome
Lexicon Pharmaceuticals

Completed

Telotristat Etiprate for Carcinoid Syndrome Therapy (TELECAST)

Carcinoid Syndrome

United States, Australia, Belgium, Canada, France, Germany, Israel, Spain, Sweden, United Kingdom, Netherlands
University Hospital, Clermont-Ferrand
Centre Leon Berard; Centre Jean Perrin; University Hospital, Grenoble; Hôpital... and other collaborators

Unknown

Randomized, Multicenter, Double-blind, Vancomycin-controlled Study to Evaluate the Efficacy of Ethanol Lock Solution for the Curative Treatment of Implantable Venous Access Port Infection Due to Coagulase-negative Staphylococci (Etha-LOCK)

Catheter Related Blood Stream Infections | Intravenous Drug Delivery Systems | Lock Solution | Central Venous Catheter Infection | Coagulase-negative Staphylococci Infection

France
Endo Pharmaceuticals

Terminated

Pharmacokinetics, Efficacy and Safety of an Octreotide Implant in Patients With Carcinoid Syndrome

Carcinoid Syndrome

United States
State University of New York - Upstate Medical...

Completed

Improving Hepatitis C Treatment in Injection Drug Users

Liver Diseases | Alcoholism | Hepatitis C | Drug Abuse

United States

Clinical Trials on Drug Therapy

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