Clinical Trials on Drug Therapy

Total 5669 results

University of California, San Francisco

Not yet recruiting

Naloxone for Opioid Associated Out of Hospital Cardiac Arrest (NOPACA)

Heart Arrest, Out-Of-Hospital | Naloxone | Opioid Overdose

United States
Damanhour University

Recruiting

Effect of Montelukast on Doxorubicin Induced Cardiotoxicity in Breast Cancer

Breast Cancer | Doxorubicin Induced Cardiotoxicity

Egypt
Taichung Veterans General Hospital
Institute of Adherence to Medication

Recruiting

Tenofovir Alafenamide Switch Therapy in Chronic Hepatitis B

Patient Satisfaction | Safety Issues | Efficacy, Self | Drug Adherence

Taiwan
Samsung Medical Center

Recruiting

Strain vs. Left Ventricular Ejection Fraction-based Cardiotoxicity Prevention in Breast Cancer

Breast Cancer | Cardiotoxicity | Prevention | Adjuvant | Trastuzumab

Korea, Republic of
Washington University School of Medicine

Recruiting

Continuous Versus Intermittent cARdiac Electrical moNitorinG (CARING)

Long QT Syndrome | Torsades de Pointe Caused by Drug

United States
Nova Scotia Health Authority
Canadian Institutes of Health Research (CIHR); Canadian Cancer Society (CCS)

Recruiting

Exercise to Prevent AnthraCycline-based Cardio-Toxicity Study 2.0 (EXACT2) (EXACT 2)

Cardiovascular Diseases | Cardiotoxicity | Cancer, Breast

Canada
The University of Hong Kong
Chinese University of Hong Kong

Completed

Acupuncture Prevents Chemobrain in Breast Cancer Patients

Breast Cancer | Mild Cognitive Impairment | Drug-Related Side Effects and Adverse Reactions | Chemo-brain

China, Hong Kong
Ipsen

Completed

Study to Evaluate the Use of Resources and the Costs Associated With Carcinoid Syndrome (CS) in Patients With NETs in Spain (RECOSY)

Neuroendocrine Tumors

Spain
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

SWOG-9342 Chemotherapy in Treating Women Enrolled in the SWOG-8897 Clinical Trial

Breast Cancer | Cardiac Toxicity

United States
University of California, San Francisco

Completed

Pharmacokinetic Interactions Between an Herbal Medicine (African Potato) and Antiretroviral Agents (Lopinavir/Ritonavir) (AP6142)

Human Immunodeficiency Virus | Drug Interactions

United States
Cancer Trials Ireland

Completed

CADY Study ICORG 08-01

Breast Cancer | Cardiac Toxicity

Ireland
TC Erciyes University

Completed

Protective Effect of N-acetylcysteine Against From Ototoxicity

Hearing Loss, Extreme

Turkey
Hacettepe University
The Scientific and Technological Research Council of Turkey

Recruiting

Efficacy of Manual Therapy Based on the Fascial Distortion Model in Individuals With Temporomandibular Disorder

Temporomandibular Joint Disorders | Temporomandibular Joint Dysfunction Syndrome | Temporomandibular Disorder | Temporomandibular Joint Pain | Manual Therapy | Temporomandibular Joint Disc Displacement

Turkey
National Cancer Institute (NCI)

Recruiting

Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

Acute Myeloid Leukemia | Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm | Acute Myeloid Leukemia Post Cytotoxic Therapy | Acute Myeloid Leukemia, Myelodysplasia-Related

United States, Puerto Rico
University of Sao Paulo General Hospital

Active, not recruiting

AGNES - Aging Nephropathy Study, a Prospective Observational Cohort of Chronic Kidney Disease in Elderly Patients (AGNES)

Mortality | Chronic Kidney Diseases | Elderly | Renal Replacement Therapy

Brazil
University of Nottingham
Nottinghamshire Healthcare NHS Trust; Lincolnshire Partnership NHS Foundation...

Completed

Video NET With CYP Who Witnessed Domestic Violence

Domestic Violence | Trauma, Psychological | Post-Traumatic Stress Disorder in Children | Narrative Exposure Therapy | Post-Traumatic Stress Disorder in Adolescence | Post-Traumatic Stress Disorder Complex

United Kingdom
Mayo Clinic

Completed

A Study to Evaluate Effects of Gargle Phonation in Voice

Voice Disorders | Speech Therapy | Muscle Tension Dysphonia

United States
Albert Einstein College of Medicine
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Long Term Outcomes of Therapy in Women Initiated on Lifelong ART Because of Pregnancy in DR Congo (CQI-PMTCT)

HIV/AIDS | Antiretroviral Therapy | Pregnancy Outcomes | HIV-exposed Infants

Congo, The Democratic Republic of the
Centre Leon Berard
CREATIS Laboratory

Completed

Phase 2 Study Evaluating Mid-position Strategy in Radiotherapy Treatment for Patients With a Locally Advanced Non-small Cell Lung Carcinoma (midP)

Non-small Cell Lung Cancer | Radiation Therapy | Locally Advanced Disease | Non-metastatic Disease | Non-resectable Disease

France
University Hospital, Montpellier

Completed

Urinary Biomarkers for AKI Diagnosis in Patients With SARS-CoV-2 (COVID-19) (COVID-AKI)

COVID-19 | Acute Kidney Injury | Renal Replacement Therapy

France
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy With or Without Chemotherapy in Reducing Mouth Dryness in Patients With Nasopharyngeal Cancer

Head and Neck Cancer | Radiation Toxicity | Oral Complications of Radiation Therapy

United States
North Central Cancer Treatment Group
National Cancer Institute (NCI)

Completed

Mometasone Furoate in Preventing Radiation Dermatitis in Patients Undergoing Radiation Therapy to the Breast or Chest Wall for Invasive Breast Cancer or Ductal Carcinoma in Situ

Breast Cancer | Radiation Toxicity | Skin Reactions Secondary to Radiation Therapy | Dermatologic Complications

United States
Solvay Pharmaceuticals

Completed

Dronabinol Versus Placebo in Treatment and Prevention of Highly Active Anti-Retroviral Therapy (HAART)-Related Nausea and Vomiting

HIV Infections | Highly Active Antiretroviral Therapy (HAART)-Related Nausea and Vomiting

United States
Benha University

Recruiting

Effects of Systemic Drugs on Intraocular Pressure

Hypertension | Glaucoma, Angle-Closure | Glaucoma Suspect | Glaucoma Secondary to Drugs, Bilateral

Egypt
Yale University

Active, not recruiting

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Substudy III (THC-ETOH-III)

Cannabis | Alcohol Effect | Driving Under the Influence of Alcohol and Other Drugs

United States
Yale University

Active, not recruiting

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study II (THC-ETOH-II)

Cannabis | Alcohol Effect | Driving Under the Influence of Alcohol and Other Drugs

United States
Yale University

Active, not recruiting

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition (THC-ETOH)

Cannabis | Alcohol Effect | Driving Under the Influence of Alcohol and Other Drugs

United States
Catholic University of the Sacred Heart
University Hospital, Geneva; Universiteit Antwerpen; Clinical Centre of Serbia; Canisius-Wilhelmina Hospital and other collaborators

Unknown

SATURN 04 Nosocomial Acquisition Study (SATURN)

Infection Due to ESBL Bacteria | Bacterial Resistance | Infection Resistant to Multiple Drugs | Staph Aureus Methicillin Resistant Colonization

Italy, Romania, Serbia
Meiyan Liu

Unknown

Study on Therapeutic Effect of Treating Mental Stress Induced Myocardial Ischemia

Theraphy of Chinese Traditional Medicine

China
Yale University

Active, not recruiting

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study I (THC-ETOH-I)

Cannabis | Alcohol Effect | Driving Under the Influence of Alcohol and Other Drugs

United States
Hasanuddin University
Chulalongkorn University

Completed

Artificial Inteligent for Diagnosing Drug-Resistant Tuberculosis

Resistance to Tuberculostatic Drugs | MDR Tuberculosis

Indonesia
Institut de cancérologie Strasbourg Europe

Not yet recruiting

Role of Sodium-glucose Linked Transporter 2 (SGLT2) and Its Inhibitor Over CARdiotoxicity Induced by Anthracyclines and Breast Cancer Tumorigenesis SCARA-B (SCARA-B)

Breast Neoplasms

France
Tanta University

Recruiting

Evaluation of Possible Safety and Efficacy of Fenofibrate in the Prophylaxis of Doxorubicin Induced Cardiotoxicity in Breast Cancer Patients

Breast Cancer Stage 2 and 3

Egypt
National Cheng-Kung University Hospital

Recruiting

Strategy Therapy on Cancer Therapy-Related Cardiac Dysfunction

Heart Failure | Lymphoma | Breast Cancer | Cardiotoxicity | Chemotherapeutic Toxicity

Taiwan
University Medical Center Groningen
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

Breast Cancer Long-term Outcomes on Cardiac Functioning: a Longitudinal Study (BLOC-II)

Heart Failure | Ventricular Dysfunction | Cardiotoxicity | Neoplasm, Breast

Netherlands
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer

Breast Carcinoma | Cardiotoxicity

United States
Baystate Medical Center
National Institute on Drug Abuse (NIDA); Tufts University; Dartmouth-Hitchcock... and other collaborators

Recruiting

Rural New England Health Study (Phase 2) (DISCERNNE)

Hepatitis C | Opioid Use Disorder | IV Drug Usage

United States
Odense University Hospital
Aarhus University Hospital; University of Copenhagen; Aalborg University Hospital

Recruiting

Imaging Versus Cardiac Biomarker Monitored HER2 Directed Therapy in Patients With Breast Cancer (HER2BIC)

HER2-positive Breast Cancer | Cardiotoxicity

Denmark
Moscow State University of Medicine and Dentistry

Recruiting

Observational Trial of Cardiotoxicity in Patients Undergoing Chemotherapy. (PROMETEY)

Heart Failure | Dilated Cardiomyopathy | Cardiotoxicity

Russian Federation
Memorial Sloan Kettering Cancer Center

Completed

Assessment for Long-Term Cardiovascular Impairment Associated With Trastuzumab Cardiotoxicity in HER2-Positive Breast Cancer Survivors

Trastuzumab Cardiotoxicity | HER2-Positive Breast Cancer Survivors

United States
Centre Hospitalier Universitaire Saint Pierre

Terminated

Intratympanic Administration of N-acetylcysteine for Protection of Cisplatin-induced Ototoxicity

Ototoxicity | Tinnitus | Ototoxic Hearing Loss | Ototoxic Hearing Loss, Bilateral

Belgium
Masaryk University

Active, not recruiting

Efficacy and Safety of TKIs' Withdrawal After a Two-step Dose Reduction in Patients With Chronic Myeloid Leukemia (HALF)

Chronic Myeloid Leukemia, Chronic Phase | Withdrawal;Drug

Czechia
Ipsen

Completed

An Efficacy and Safety Study of Somatuline Depot (Lanreotide) Injection to Treat Carcinoid Syndrome (ELECT)

Carcinoid Syndrome

United States, Turkey, Brazil, India, Ukraine, South Africa, Czechia, Latvia, Poland, Russian Federation, Serbia
Radboud University Medical Center

Unknown

Early Detection of Cardiac Damage With CMR in Women With Breast Cancer (EARLY-CATCH)

Breast Cancer | Cardiotoxicity | Chemotherapy Induced Systolic Dysfunction

Netherlands
Medical University of South Carolina
National Institute on Drug Abuse (NIDA)

Completed

Integrated Treatment of OEF/OIF Veterans With PTSD & Substance Use Disorders (COPE)

Alcohol Dependence | Posttraumatic Stress Disorders | Combat Disorders | Drug Dependence

United States
Vancouver Infectious Diseases Centre

Unknown

Switching to a Fixed Dose Combination of Bictegravir/Emtricitabine/Tenofovir Alafenamide (B/F/TAF) in HIV-1 Infected Marginalized Populations Who Are Virologically Suppressed

Drug Use | Human Immunodeficiency Virus I Infection

Canada
Lexicon Pharmaceuticals

Completed

Telotristat Etiprate - Expanded Treatment for Patients With Carcinoid Syndrome Symptoms (TELEPATH)

Carcinoid Syndrome

United States, Australia, Belgium, Canada, France, Germany, Israel, Italy, Netherlands, Spain, Sweden, United Kingdom
Mansoura University

Completed

Trigonal vs Non Trigonal Botox Injection in OAB.

Quality of Life | Urologic Diseases | Overactive Bladder Syndrome | Anticholinergic Syndrome
Lexicon Pharmaceuticals

Completed

Telotristat Etiprate for Carcinoid Syndrome Therapy (TELECAST)

Carcinoid Syndrome

United States, Australia, Belgium, Canada, France, Germany, Israel, Spain, Sweden, United Kingdom, Netherlands
University Hospital, Clermont-Ferrand
Centre Leon Berard; Centre Jean Perrin; University Hospital, Grenoble; Hôpital... and other collaborators

Unknown

Randomized, Multicenter, Double-blind, Vancomycin-controlled Study to Evaluate the Efficacy of Ethanol Lock Solution for the Curative Treatment of Implantable Venous Access Port Infection Due to Coagulase-negative Staphylococci (Etha-LOCK)

Catheter Related Blood Stream Infections | Intravenous Drug Delivery Systems | Lock Solution | Central Venous Catheter Infection | Coagulase-negative Staphylococci Infection

France

Clinical Trials on Drug Therapy

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CROs in Bahrain

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