Clinical Trials on Drug Use

Total 7630 results

Affiliated Hospital of Qinghai University

Not yet recruiting

Cardiotoxicity of Targeted Therapy for HER-2 Positive Breast Cancer Patients at High Altitude

HER2-positive Breast Cancer | Targeted Therapy | Cardiac Toxicity | High Altitude

China
AHS Cancer Control Alberta
Cross Cancer Institute

Completed

A Prospective Study of Acute Cardiovascular Effects of First-line Sunitinib in Metastatic Renal Cell Carcinoma Patients (SUnitinib Prospective CardiovasculaR Effect) (SUPER)

Heart Failure | Renal Cell Carcinoma | Hypertension | Cardiotoxicity

Canada
Konya City Hospital

Completed

Combined Use of Immunoglobulin and Pulse Steroid Therapies in Severe Covid-19 Patients

Pulse Steroid and Immunoglobulins Drugs in Covid 19 Patients

Turkey
Umeå University
Medtronic

Completed

Preoperative Dual Antiplatelet Therapy: Platelet Function and Influence of Cardiopulmonary Bypass

Cardiopulmonary Bypass | Bleeding Disorder | Platelet Dysfunction Due to Drugs | Platelet Disorder

Sweden
University Hospital, Akershus
University of Oslo; Helse Stavanger HF

Active, not recruiting

Scandinavian Multicenter Study to Advance Risk Stratification in Heart Disease- Ventricular Arrhythmias (SMASH 1)

Heart Disease | Ventricular Arrhythmias | Implantable Defibrillator User | Biological Markers

Norway
Queen Mary University of London
Royal Free Hospital NHS Foundation Trust

Active, not recruiting

Investigation of a Transcatheter Tricuspid Valved Stent Graft in Patients With Carcinoid Heart Disease (TRICAR)

Carcinoid Syndrome | Carcinoid Heart Disease | Tricuspid Regurgitation | Tricuspid Valve Disease

United Kingdom
University Hospital Inselspital, Berne
University of Bern; Spital STS AG; Bürgerspital Solothurn; Lindenhofspital

Terminated

Cancer Adverse Effects PReventIon With Care & Exercise: the CAPRICE Study

Lymphoma | Physical Activity | Breast Neoplasm Female | Cardiotoxicity | Anthracyclines

Switzerland
University College, London

Recruiting

Cancer Treatment Related Cardiovascular Toxicity: Comprehensive Myocardial and Vascular Phenotyping (PC-TOX)

Cardiovascular Diseases | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Cardiotoxicity | Malignancy | Oesophagus Cancer | Fluorouracil Adverse Reaction

United Kingdom
Korea University Guro Hospital
Yonsei University; Boryung Pharmaceutical Co., Ltd; Chong Kun Dang Pharmaceutical...

Recruiting

Secondary Cytoreductive Surgery (CRS) in Patients With Relapsed Ovarian Cancer Who Have Progressed on PARP Inhibitor Maintenance (SOCCER-P)

Ovarian Cancer | Drug Related Neoplasm/Cancer

Korea, Republic of
Memorial Sloan Kettering Cancer Center

Recruiting

Study of Cardiopulmonary Exercise Testing in Women Who Have HER2-Positive Breast Cancer With Mild Cardiotoxicity

Breast Cancer | HER2-positive Breast Cancer | Cardiotoxicity | Breast Cancer Stage IV | Breast Cancer Stage I | Breast Cancer Stage II | Breast Cancer Stage III | HER2-positive Metastatic Breast Cancer

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia or Advanced Lymphoblastic Non-Hodgkin's Lymphoma (T-Cell #4)

Lymphoma | Leukemia | Cardiac Toxicity
Northwestern University
University of Washington

Completed

Targeted Reinnervation for Neuromas as a Means to Improve Prosthesis Control in Major Limb Amputation

Pain | Prosthesis User | Neuroma | Prosthesis Failure

United States
Mayo Clinic
Esaote North America

Completed

CIMT and Plaque Assessment Findings in Subjects Undergoing Stress Echocardiography For Risk Stratification

Cardiovascular Risk Stratification | Carotid Intima-media Thickness (CIMT) | Stress Echocardiography (SE)

United States
Atrial Fibrillation Network

Completed

Prospective Registration and Assessment of Serious Adverse Events Within the AFNET (AFNET A7)

Atrial Fibrillation | Assessment of Serious Advers Events | Thromboembolic and Bleeding Complications | Complications of Antiarrhythmic Drugs or Invasive Procedures | Assessment by a Critical Event Committee

Germany
University of Wisconsin, Madison
National Cancer Institute (NCI)

Completed

COVID EHR COHORT at the University of Wisconsin (CEC-UW)

Cardiovascular Diseases | COVID-19 | Cancer | Pulmonary Disease | Nicotine Dependence | Immunosuppression Disorders

United States
VA Office of Research and Development

Completed

Supported Employment in Patient Aligned Care Teams

Major Depressive Disorder | Substance Use Disorders | Posttraumatic Stress Disorder | Mental Disorder | Anxiety Disorder

United States
VA Office of Research and Development

Completed

Cardiovascular Risk Screening and Risk Reduction in Women Vets

Cardiovascular Diseases | Hypertension | Obesity | Diabetes Mellitus | Overweight | Dyslipidemias | Tobacco Use Disorder | Hyperlipidemias

United States
Innovent Biologics (Suzhou) Co. Ltd.

Completed

Efficacy and Safety Evaluation of IBI308 in Patients With Extranodal NK/T Cell Lymphoma Patients (ORIENT-4)

Effect of Drugs

China
Diamyd Medical AB

Completed

Diamyd Administered Into Lymph Nodes in Combination With Vitamin D in Type 1 Diabetes

Glucose Metabolism Disorders | Immune System Diseases | Autoimmune Diseases | Diabetes Mellitus | Endocrine System Diseases | Diabetes Mellitus, Type 1 | Metabolic Disease | Vitamin D | Autoimmune Diabetes | Physiological Effects of Drugs | Juvenile Diabetes | Insulin Dependent Diabetes

Czechia, Netherlands, Spain, Sweden
First Affiliated Hospital of Jinan University

Completed

Hospital Processes Reengineering of Intravenous Thrombolysis in Acute Ischemic Stroke in China (PROMISE)

Ischemic Stroke | Adverse Effect of Thrombolytic Drugs, Sequela
Yong Zeng

Recruiting

Deep Learning Algorithm for Detecting Obstructive Coronary Artery Disease Using Fundus Photographs

Coronary Artery Disease | Artificial Heart Device User

China
University Hospital of Ferrara

Completed

Ultrasound Guided Axillary Access vs Standard Fluoroscopic Technique for Cardiac Lead Implantation: ZEROFLUOROAXI TRIAL (ZEROFLUOROAXI)

Arrhythmias, Cardiac | Implantable Defibrillator User | Vascular Access Complication | Venous Puncture | Pacemaker Complication | Fluoroscopy; Adverse Effect

Italy
Jonas Malmstedt

Completed

HRQoL Among Patients Amputated Due to Peripheral Arterial Disease

Quality of Life | Peripheral Arterial Disease | Amputation | Prosthesis User

Sweden
University of Oklahoma
Centers for Disease Control and Prevention

Completed

Development of Education Materials for Prevention of FAS in Russia

Fetal Alcohol Spectrum Disorders | Fetal Alcohol Syndrome (FAS) | Alcohol Related Neurodevelopmental Disorder | Alcohol Use Complicating Pregnancy, Unspecified Trimester

United States, Russian Federation
Federal University of Mato Grosso

Completed

Safety of Gastric Volume Emptying After the Intake of Maltodextrin and Glutamine

Pulmonary Aspiration of Gastric Contents | Adverse Effects in the Therapeutic Use of Other and Unspecified General Anaesthetics | Pulmonary Aspiration During Anaesthetic Induction

Brazil
Abramson Cancer Center at Penn Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Pilot Study of an NTproBNP Guided Strategy of Cardioprotection (NTproBNP-Guide)

Heart Failure | Lymphoma | Breast Cancer | Cardiomyopathies | Cardiotoxicity | Toxicity Due to Chemotherapy

United States
Tanta University

Enrolling by invitation

Role of Silymarin in Chemotherapy Toxicity and Cognition Improvement in Breast Cancer Patients

Breast Cancer | Cognitive Impairment | Peripheral Neuropathy | Cardiac Toxicities | Hepatic Toxicity

Egypt
Changhai Hospital

Completed

Serum HBV RNA Value on Chronic Hepatitis B Virus Infection Manage

Chronic HBV Infection | Drug Withdrawal
Rachel Miller
Office of US Army Medical Research and Material Command

Completed

Chemotherapy-Induced Cognitive Impairment in Ovarian Cancer Patients

Chemotherapy-induced Cognitive Impairment

United States
University Hospital, Lille
MSDAVENIR Foundation

Recruiting

Characteristics of Marrow Fatty Cells in the Ageing of Bone and Joints, Osteoarthritis and Osteoporosis (MEDADIPO)

Osteoarthritis, Knee | Prosthesis User

France
Hospital Universitario 12 de Octubre

Not yet recruiting

Registry of Patients in Shock Treated With Vasopressin

Shock | Vasopressor Adverse Reaction | Vasopressin Causing Adverse Effects in Therapeutic Use | Vasopressin Deficiency

Spain
University of Connecticut

Recruiting

Assessing the PrEP Care Cascade Among Black Men and Transwomen in the Southeastern US

HIV Seropositivity | Substance Use | STI | Stigma, Social

United States
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Completed

Remote Guided Caffeine Reduction

Sleep Disorder | Diarrhea | Anxiety Disorders | Insomnia | Sleep Initiation and Maintenance Disorders | Anxiety | Sleep Disturbance | Gastrointestinal Dysfunction | Heartburn | Caffeine | Caffeine Withdrawal | Caffeine; Sleep Disorder | Caffeine Dependence | Caffeine-Induced Anxiety Disorder | Caffeine-Induced Sleep... and other conditions

United States
Keller Army Community Hospital

Completed

Effect of Battlefield Acupuncture and Physical Therapy Versus Physical Therapy Alone After Shoulder Surgery

Pain, Postoperative | Rotator Cuff Tear | Subacromial Impingement Syndrome | Bankart Lesion | SLAP Lesion | Opioid Use | Glenohumeral Subluxation | Glenohumeral Dislocation | Hill Sach Lesion | Bony Bankart Lesion | Acromioclavicular Separation

United States
Wayne State University
National Institute on Drug Abuse (NIDA)

Completed

Medical Marijuana Use in HIV+ Patients Prospective Cohort Study (MMC-1)

Marijuana Smoking | HIV Positive

United States
Xijing Hospital

Completed

Epileptic Seizure in Epilepsy Patients After SARS-CoV-2 Vaccination

Vaccine Adverse Reaction | SARS-CoV-2 Acute Respiratory Disease | Epileptic Seizures Related to Drugs

China
Yale University
National Institute on Drug Abuse (NIDA); University of Malaya

Completed

Intervention of HIV, Drug Use and the Criminal Justice System in Malaysia (Harapan)

Acquired Immunodeficiency Syndrome | Human Immunodeficiency Virus | Opiate Addiction | Drug Dependence
Azienda Ospedaliero-Universitaria Consorziale Policlinico...
Catholic University of the Sacred Heart; Institute of Biomembranes, Bioenergetics... and other collaborators

Completed

Establishment of the Human Intestinal and Salivary Microbiota Biobank - Gastrointestinal Diseases (BIOMIS-Gastr)

Hepatic Encephalopathy | Irritable Bowel Syndrome | Clostridium Difficile Infection | Chronic Inflammatory Bowel Disease | Multi Drug Resistant Organisms

Italy
Universidad del Norte

Unknown

Piperacillin/Tazobactam Versus Carbapenems in Non-bacteremic UTI Due to -ESBL-producing Enterobacteriaceae (CAPITIS)

Urinary Tract Infections | Enterobacteriaceae Infections | Clinical Trial | Carbapenem | Klebsiella Pneumoniae Infection | Infection Due to ESBL Bacteria | Escherichia Coli Infection | Drug Resistance, Bacterial

Colombia
Nova Scotia Health Authority
Maritime Heart Centre

Recruiting

END - VT Cohort Study (END VT)

Ventricular Tachycardia | Implantable Defibrillator User | ICD

Canada
Sun Yat-sen University

Recruiting

Evaluation of Impedance Cardiography for Assessing Hemodynamic Shifts in Patients With LA-NSCLC During Treatment.

Non-small Cell Lung Cancer | Cardiac Toxicity

China
Lei Li

Recruiting

HRD and Resistance to PAPPi in EOC Patients

Epithelial Ovarian Cancer | Homologous Recombination Deficiency | Homologous Recombination Repair Gene Mutation | Drug Resistance | Overall Survival | Progression-free Survival | Poly(ADP-ribose) Polymerase Inhibitor

China
Military Institute of Medicine, Poland

Recruiting

Radiation-induced Cardiac Toxicity After Non-small Cell Lung Cancer Radiotherapy

Non-small Cell Lung Cancer | Radiation Toxicity | Cardiac Toxicity

Poland
Dana-Farber Cancer Institute
AstraZeneca

Withdrawn

Cardiotoxicities in Patients Receiving BTKi

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
Abramson Cancer Center at Penn Medicine

Enrolling by invitation

Hypertension and Arrhythmias in CLL Patients Treated With BTK Inhibitors (SENTINEL)

Hypertension | Atrial Fibrillation | Chronic Lymphocytic Leukemia | Cardiotoxicity

United States
Yale University
The New York Academy of Medicine

Completed

Buprenorphine and Integrated HIV Care

HIV Infections | Human Immunodeficiency Virus | Substance-related Disorders | Drug Addiction | AIDS

United States
National Cancer Institute (NCI)

Completed

Radiation Therapy, Bevacizumab, Paclitaxel, and Carboplatin in Treating Patients With Unresectable Stage IIIB or Stage IV Non-Small Cell Lung Cancer at High Risk for Hemoptysis Caused by Bevacizumab

Stage IIIB Non-small Cell Lung Cancer | Stage IV Non-small Cell Lung Cancer | Squamous Cell Lung Cancer | Drug/Agent Toxicity by Tissue/Organ | Adenosquamous Cell Lung Cancer | Hemoptysis
Istituto Auxologico Italiano

Completed

Effect of Pharmacological Interventions on Systolic Blood Pressure Drops (SynABPM 2 Proof-of-concept) (SynABPM)

Syncope | Orthostatic Hypotension | Syncope, Vasovagal | Ambulatory Blood Pressure Monitoring | Antihypertensive Drugs

Italy
London School of Hygiene and Tropical Medicine
University of Sierra Leone; Janssen Vaccines & Prevention B.V.

Active, not recruiting

Ad26.ZEBOV, MVA-BN-Filo Vaccination in Children and Adults Previously Vaccinated With Control in the EBOVAC-Salone Study

Infections | RNA Virus Infections | Virus Diseases | Mononegavirales Infections | Hemorrhagic Fevers, Viral | Hemorrhagic Fever, Ebola | Filoviridae Infections | Physiological Effects of Drugs | Vaccines | Ebola | Immunologic Factors

Sierra Leone
Center For Hepatitis C, Atlanta, GA

Active, not recruiting

Treatment of HCV-Infected Recent Injection Drug Users in U.S. Liver Clinics

Chronic Hepatitis C | People Who Inject Drugs

United States

Clinical Trials on Drug Use

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