Clinical Trials on Early Phase of Severe Sepsis and Septic Shock

Total 1223 results

Wuerzburg University Hospital

Withdrawn

Volume Therapy With Crystalloids and Colloids and Hemodynamic Monitoring in Patients With Severe Sepsis (VOMOSEP)

Severe Sepsis
Lawson Health Research Institute

Unknown

Outcome Following Vitamin C Administration in Sepsis

Severe Sepsis

Canada
Centre Hospitalier Universitaire de Saint Etienne
National Research Agency, France

Completed

Platelet-associated Inflammation in Severe Sepsis (PlatISSep)

Severe Sepsis

France
Assiut University

Unknown

Procalcitonin in Diagnosis of Sepsis in Critically Ill Patient

Sepsis, Severe
Dascena

Completed

Effect of a Sepsis Prediction Algorithm on Clinical Outcomes

Severe Sepsis
University of Aarhus

Completed

Piperacillin PK Analysis in Severe Sepsis Patients

Sepsis | Severe Sepsis

Denmark
Eisai Inc.

Completed

ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients With Severe Sepsis

Severe Sepsis

United States, France, Poland, United Kingdom, Germany, Hong Kong, Taiwan, Spain, Switzerland, Argentina, Belgium, Israel, South Africa, Japan, Canada, Netherlands, Korea, Republic of, Australia, Chile, Brazil, Austria, Italy, Czechia, Portug...
Radovan Uvizl

Unknown

The Benefits of Early Initiation of Continual Renal Replacement Therapy in Patients With Severe Sepsis

Severe Sepsis
Pavol Jozef Safarik University

Completed

Therapeutic Effect of Sodium Selenite on Oxidative Stress in Patients With Severe Sepsis (Se-AOX)

Severe Sepsis

Slovakia
Christiana Care Health Services
Therapeutic Monitoring Systems; MaRS Discovery District

Completed

The AVERT Sepsis Investigation (AVERT)

Sepsis | Severe Sepsis

United States, Canada
Assistance Publique Hopitaux De Marseille

Completed

De-escalation of Empirical Antimicrobial Therapy Study in Severe Sepsis

Severe Sepsis

France
Belinda Howe
Australian and New Zealand Intensive Care Society Clinical Trials Group; Australasian...

Unknown

Australasian Resuscitation In Sepsis Evaluation Randomised Controlled Trial (ARISE)

Severe Sepsis

New Zealand, Australia, Finland, Ireland, Hong Kong
Shandong University
Shandong Provincial Hospital

Recruiting

Population Pharmacokinetic of Piperacillin/Tazobactam in Maternal and Neonatal Populations

Early-Onset Neonatal Sepsis

China
Oslo University Hospital

Recruiting

Diagnostic Accuracy in Sepsis

Sepsis Syndrome

Norway
Maimónides Biomedical Research Institute of Córdoba

Unknown

Clinical Trial for Valuation of the Effectiveness of Lactoferrine in the Prevention of Sepsis in New Premature Born. Bimonitorization of the Antinflammatory Mechanisms, Antioxidants and the Intestinal Microbiote. (LACTOPREM)

SEPSIS SYNDROME

Spain
Artcline GmbH
ZKS Jena

Recruiting

Recovery From Acute Immune Failure in Septic Shock by Immune Cell Extracorporeal Therapy - Observational Long-term Outcome Follow up (ReActIF- LTO)

Severe Sepsis

Germany
Rennes University Hospital

Completed

Effects of Acute Systemic Inflammation on Arterial Stiffness and Microcirculation. (IRIGA)

Severe Sepsis

France
Tunis University

Recruiting

Early Administration of Norepinephrine in Sepsis (EA-NE-TUN)

Sepsis, Severe

Tunisia
University of Milano Bicocca

Completed

Lotta Alla Sepsi Ospedaliera - Fighting Hospital Sepsis

Severe Sepsis

Italy
Cairo University

Completed

Effect of Probiotics on Cytokines in Sepsis in Children

Sepsis, Severe

Egypt
Lawson Health Research Institute
Schulich School of Medicine and Dentistry

Completed

Targeted Exercise Intervention to Reduce Morbidity and Mortality in Sepsis (TERMS)

Severe Sepsis

Canada
University of Oxford
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health... and other collaborators

Completed

Causes and Factors Associated With Outcomes in Community-acquired Sepsis and Severe Sepsis in Northeast Thailand

Sepsis | Severe Sepsis

Thailand
Centre Hospitalier Universitaire, Amiens

Unknown

Descriptive Study of the Evolution in Proportion of Regulatory B Lymphocytes in Patients Hospitalized in Intensive Care for Severe Sepsis (DELyBREG)

Severe Sepsis

France
Klinikum St. Georg gGmbH
University of Halle Medical Faculty

Terminated

Alterations of Immunologic Mediators During Severe Sepsis (LAVISS_01)

Severe Sepsis

Germany
Stanford University

Completed

Study of an Electronic Health Record-embedded Severe Sepsis Early Warning Alert

Severe Sepsis

United States
Corporacion Parc Tauli

Unknown

Monitoring Resuscitation in Severe Sepsis and Septic Shock

Hemodynamics

Spain
Agennix

Suspended

Safety and Efficacy of Talactoferrin Alfa in Patients With Severe Sepsis (OASIS)

Severe Sepsis

United States, Spain, Belgium, France, United Kingdom, Canada, Israel, Germany, Denmark, Netherlands
Central Hospital, Nancy, France

Unknown

Evaluation of MorphoTEP With the FDG Among Patients in Severe Sepsis of Unspecified Etiology

Severe Sepsis

France
Charite University, Berlin, Germany
German Research Foundation; adexter GmbH

Completed

Immunoadsorption of LPS, C5a and IL-6 in Severe Sepsis and Septic Shock (ISASS-1)

Septicemia

Germany
Eli Lilly and Company

Completed

An Open Label Study of Severe Sepsis in Adults

Severe Sepsis

Belgium
Artcline GmbH
Zentrum für Klinische Studien Jena; CRO Kottmann

Recruiting

Recovery From Acute Immune Failure in Septic Shock by Immune Cell Extracorporeal Therapy (ReActiF-ICE)

Sepsis, Severe

Germany
Onze Lieve Vrouwe Gasthuis

Unknown

Microcirculation Guided Therapy Versus "Standard Treatment" of Severe Sepsis

Severe Sepsis | Microcirculation

Netherlands
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France

Terminated

Comparative Study of the Protein C Pathway in Septic and Non Septic Patients With Organ Failure

Severe Sepsis | Organ Failure
Jip Groen
InBiome

Recruiting

Molecular Culture for the Diagnosis of Neonatal Sepsis

Microbial Colonization | Neonatal Infection | Neonatal Sepsis, Early-Onset | Microbial Disease | Clinical Sepsis | Culture Negative Neonatal Sepsis | Neonatal Sepsis, Late-Onset | Culture Positive Neonatal Sepsis

Netherlands
Pfizer

Completed

Pharmacoeconomic Analysis of First Line Meropenem Versus Standard Antibiotic Treatment in Seriously Infected Secondary Nosocomial Sepsis Syndrome Patients.

Sepsis

Hungary
Enlivex Therapeutics Ltd.

Completed

Prevention of Sepsis-related Organ Dysfunction With Allocetra-OTS (P-SOFA-1)

Organ Dysfunction Syndrome Sepsis

Israel
Charalambos .A. Gogos
University Hospital of Patras; Hellenic Society for Chemotherapy : Hellenic...

Completed

Platelet REactivity in Sepsis Syndrome (PRESS) (PRESS)

Sepsis Syndrome

Greece
Brno University Hospital

Unknown

Utility of Presepsin in Children Sepsis

Sepsis Syndrome

Czech Republic
Peking Union Medical College Hospital

Unknown

Assessment of Transcutaneous Oxygen Tension/Oxygen Challenge Test in Intensive Care Unit (ICU) Patients (ICUPtO2OCT)

Sepsis | Shock

China
Nanjing PLA General Hospital

Completed

the Influence of Prophylactic and Empirical Anti-fungal Treatment in Severe Sepsis Patients With Perforations

Intra-abdominal Perforation
Coordinación de Investigación en Salud, Mexico

Completed

Effect of Docosahexaenoic Acid on the Inflammatory Response and Clinical Outcomes From Surgical Patients (DHA-IRCO)

Severe Sepsis | Organ Dysfunction Syndrome

Mexico
Hospital Italiano de Buenos Aires

Completed

Sepsis Institutional Registry in Hospital Italiano de Buenos Aires (SIR)

Death | Severe Sepsis

Argentina
Brahms France

Terminated

Study of Procalcitonin (PCT)-Guided Antibiotic Use in Severe Sepsis Patients Without Obvious Infection (Pro-SEPS)

Severe Sepsis

France
Mansoura University Children Hospital

Recruiting

Performance of Interleukin-27 Cord Blood Level as A Biomarker Predicating Early Onset Neonatal Sepsis

Neonatal Sepsis, Early-Onset

United Arab Emirates
Shandong University
Shandong Provincial Hospital; Qianfoshan Hospital; Tianjin Central Hospital of...

Recruiting

Antibiotic Therapy for Early Onset Neonatal Sepsis

Early Onset Neonatal Sepsis

China
Luzerner Kantonsspital

Completed

Procalcitonin-Guided Decision Making to Shorten Antibiotic Therapy in Suspected Neonatal Early-Onset Sepsis

Sepsis

Switzerland
University of Tartu
Estonian Science Foundation; European Society for Paediatric Infectious Diseases

Completed

Management of Early Onset Neonatal Septicaemia: Selection of Optimal Antibacterial Regimen for Empiric Treatment

Early Onset Neonatal Sepsis

Estonia
Assistance Publique - Hôpitaux de Paris
Commissariat A L'energie Atomique; Laboratoire National de Métrologie et d'essais

Recruiting

Metrology to Enable Rapid and Accurate Clinical Measurements in Acute Management of Sepsis (SEPTIMET)

Sepsis Syndrome

France
Charles University, Czech Republic

Completed

The Role of Myristic Acid in Serum for Early Diagnosis of Sepsis and Comparison With Selected Biomarkers of Sepsis

Systemic Inflammatory Response Syndrome | Sepsis Syndrome

Czechia
University of Vermont
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Zinc Therapy in Critical Illness

Severe Sepsis

United States

Clinical Trials on Early Phase of Severe Sepsis and Septic Shock

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