Clinical Trials on Eicosapentaenoic Acid

Total 1213 results

APR Applied Pharma Research s.a.

Recruiting

Open-label, Randomized, 2-way Crossover, Monocentric, Controlled Study to Evaluate the Effect on Daily PHE Fluctuation of PKU GOLIKE Versus SoC in Patients With PKU.

Phenylketonurias

Italy
University Children's Hospital, Zurich
University Children's Hospital Basel; UChildrenVienna; Insel Gruppe AG, University...

Recruiting

Metabolic Control and Patient Well-being in Phenylketonuria: do Guidelines Make a Difference? (PKU_Guide)

Phenylketonurias

Switzerland
University Hospital, Lille

Not yet recruiting

Life With Phenylketonuria. Adult Neurological Outcome of PCU Screened Patients From 1971 to 2002. (PCU)

Phenylketonurias
Emory University
BioMarin Pharmaceutical

Recruiting

Nutritional Impacts of Palynziq on Patients With Phenylketonuria (PKU)

Phenylketonurias

United States
University of Pennsylvania

Enrolling by invitation

Effects of Ketone Supplementation on Acute Alcohol Withdrawal

Alcohol Dependence | Alcohol Use Disorder | Ketosis | Alcohol Withdrawal

United States
Vitaflo International, Ltd

Completed

Evaluation of PKU Sphere Liquid

Phenylketonurias

United Kingdom
Vitaflo International, Ltd
Johannes Gutenberg University Mainz; Kreiskliniken Reutlingen

Completed

A 16 Week Study Evaluating the Introduction of a GMP Based Protein Substitute in Participants With PKU (GMP In PKU)

Phenylketonurias

Germany
Klaus Parhofer

Terminated

Short-term Effects of Good Metabolic Control on Cognitive Function, Wellbeing, and Metabolic Parameters in Adult Patients With Phenylketonuria

Phenylketonurias

Germany
Nutricia UK Ltd

Completed

GMP Case Studies of Tolerance, Safety and Acceptability in PKU and TYR

PKU | Tyrosinemias

United Kingdom
Cukurova University

Completed

The Effect of Nursing Empowerment Program

Phenylketonurias

Turkey
BioMarin Pharmaceutical

Completed

Kuvan®'s Effect on the Cognition of Children With Phenylketonuria (KOGNITO)

Phenylketonuria

Italy, Spain, United Kingdom, Germany
Rubius Therapeutics

Terminated

Safety and Tolerability of RTX-134 in Adults With Phenylketonuria

Phenylketonurias

United States
Ludwig-Maximilians - University of Munich
European Union

Completed

Quantitative Requirements of Docosahexaenoic Acid for Neural Function in Children With Phenylketonuria

Phenylketonuria

Germany, Italy, Spain, United Kingdom
Florence Nightingale Hospital, Istanbul

Completed

Arthroscopic Rotator Cuff Repair Performed With Intraarticular Tranexamic Acid Could it Provide Improved Visual Clarity and Less Post-operative Pain? A Prospective, Double Blind, Randomized Study of 64 Patients.

Rotator Cuff Tears | Rotator Cuff Rupture | Tranexamic Acid | Shoulder Arthroscopy | Visual Clarity

Turkey
BioMarin Pharmaceutical

Completed

Long-Term Extension of Previous rAvPAL-PEG Protocols in Subjects With PKU (PAL-003)

Phenylketonuria

United States
Synlogic

Completed

Safety and Tolerability of SYNB1618 in Healthy Adult Volunteers and Adult Subjects With Phenylketonuria (PKU)

Healthy | Phenylketonuria

United States
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Trial to Understand Efficacy of Colesevelam in Diarrhea Predominant IBS Patients With Bile Acid Malabsorption

Irritable Bowel Syndrome With Diarrhea | Bile Acid Malabsorption | Chronic Diarrhea

United States
Assiut University

Unknown

Early Dietary Treated Patients With Phenylketonuria Can Achieve Normal Growth and Mental Development.

Phenylketonurias
Boston Children's Hospital
Brigham and Women's Hospital

Completed

MRI Spectroscopy and Neuropsychological Functioning in Phenylketonuria

Phenylketonuria

United States
Washington University School of Medicine
University of Missouri-Columbia; BioMarin Pharmaceutical

Completed

Sapropterin in Individuals With Phenylketonuria

Phenylketonuria

United States
University Medical Center Groningen
UMC Utrecht; University of Oxford; Academisch Medisch Centrum - Universiteit... and other collaborators

Completed

Acute Nutritional Ketosis in VLCAD Deficiency

VLCAD Deficiency | Fatty Acid Oxidation Defects

Netherlands
Universiti Sains Malaysia

Completed

Efficacy of Gaviscon-Advance® in Suppressing Post-supper Acid-pocket and Night-time Acid-reflux in Obese Participants

Obesity | Gastroesophageal Reflux Disease | Acid Reflux

Malaysia
Boston Children's Hospital
Beth Israel Deaconess Medical Center; Brigham and Women's Hospital

Completed

The Brain and Neuropsychological Functioning in Adults With Sapropterin Dihydrochloride Treated Phenylketonuria

Phenylketonuria

United States
University of Missouri-Columbia
BioMarin Pharmaceutical

Completed

The Effects of Kuvan on Functional Brain Connectivity in Individuals With Phenylketonuria (PKU)

Phenylketonuria

United States
BioMarin Pharmaceutical

Completed

Safety and Tolerability Study of rAvPAL-PEG to Treat Phenylketonuria

Phenylketonuria

United States
Alexion Pharmaceuticals

Terminated

A Study to Identify and Characterize LAL-D Patients in High-risk Populations

Lysosomal Acid Lipase Deficiency

United States
BioMarin Pharmaceutical

Completed

Safety and Therapeutic Effects of Sapropterin Dihydrochloride on Neuropsychiatric Symptoms in Phenylketonuria (PKU) Patients

Phenylketonuria

United States, Canada
Emory University
Atlanta Clinical and Translational Science Institute

Completed

The Effect of Supplemental Docosahexaenoic Acid (DHA) on Neurocognitive Outcomes in Teen and Adult Women With Phenylketonuria(PKU) (PKU&DHA)

Phenylketonuria

United States
The University of Texas Health Science Center,...
BioMarin Pharmaceutical

Terminated

Bone Mineral Density in Adults With Hyperphenylalaninemia on Kuvan Therapy

Phenylketonuria | Hyperphenylalaninemia

United States
Boston Children's Hospital
Beth Israel Deaconess Medical Center; Brigham and Women's Hospital

Completed

The Brain, Neurological Features and Neuropsychological Functioning in Adults With Phenylketonuria: A Pilot Study

Phenylketonuria

United States
The University of Texas Health Science Center,...
BioMarin Pharmaceutical

Completed

Bone Mineral Density in Adults With Hyperphenylalaninemia

Phenylketonurias

United States
Emory University

Terminated

Phenylketonuria, Oxidative Stress, and BH4

Phenylketonuria

United States
Merck KGaA, Darmstadt, Germany

Completed

Phase 3 Open-label Study to Evaluate the Response and Safety of Kuvan® in Subjects With Phenylketonuria

Phenylketonuria

Germany
BioMarin Pharmaceutical

Completed

Study to Evaluate the Safety and Efficacy of Phenoptin™ in Subjects With Phenylketonuria Who Have Elevated Phenylalanine Levels

Phenylketonurias

United States
Shoji Yano
BioMarin Pharmaceutical

Completed

Study to Evaluate the Effects of Kuvan on Individuals With Phenylketonuria (PKU) With Maladaptive Behaviors

Phenylketonuria

United States
BioMarin Pharmaceutical

Completed

A Phase 3, Multicenter, Open-Label Extension Study of Phenoptin in Subjects With PKU Who Have Elevated Phenylalanine Levels

Phenylketonurias

United States
BioMarin Pharmaceutical

Approved for marketing

Sapropterin Expanded Access Program

Phenylketonuria

United States
BioMarin Pharmaceutical

Completed

Study to Evaluate the Response to and Safety of an 8-Day Course of Phenoptin™ Treatment in Subjects With Phenylketonuria

Phenylketonurias

United States
University Ghent
Institut de Recherche en Sciences de la Sante, Burkina Faso; Addis Ababa University and other collaborators

Recruiting

Effectiveness of Fortification With Folic Acid and Vitamin B12 Among Teenage Girls

Depressive Symptoms | Vitamin B 12 Deficiency | Folate Deficiency | Cognitive Development | Anemia, Megaloblastic

Ethiopia
BioMarin Pharmaceutical

Active, not recruiting

Study to Evaluate the Safety and Efficacy of Pegvaliase in Adolescents (Ages 12-17) With Phenylketonuria (PEGASUS)

Phenylketonuria (PKU)

United States, Germany
Akdeniz University
Ceren Kahraman

Completed

Diabetic Ketoacidosis Diagnosis and Management

Diabetic Ketoacidosis | Brain Edema | Metabolic Acidosis

Turkey
metaX Institut fuer Diatetik GmbH
Birmingham Children's Hospital

Completed

Acceptability and Tolerance of a Ready-to-use Protein Substitute in Tablet Form for the Dietary Management of Phenylketonuria

Phenylketonurias | Hyperphenylalaninaemia | Tetrahydrobiopterin Deficiency

United Kingdom
Hydrocephalus and Neuroscience Institute

Completed

Salt-FA to Increase Folate Levels

Folic Acid Deficiency | Neural Tube Defects | Spina Bifida | Anencephaly-Spina Bifida

United States
University of Aarhus

Completed

Modulation of Circulating Levels of the Ketone Body 3-hydroxybutyrate in Patients With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction: Metabolic Effects. (KETO-HFpEF-Metabolic)

Diabetes Mellitus, Type 2 | Heart Failure With Preserved Ejection Fraction | Ketonemia

Denmark
Homology Medicines, Inc

Enrolling by invitation

Long-Term Follow Up Study of Subjects Previously Administered HMI 102

Phenylketonuria | PAH Deficiency

United States
BioMarin Pharmaceutical

Completed

Safety and Efficacy of Self Administered Injections of Pegvaliase (>40mg/Day Dose) in Adults With PKU

Phenylketonuria (PKU)

United States
BioMarin Pharmaceutical

Completed

Phase 3 Study to Evaluate the Efficacy & Safety of Self-Administered Injections of BMN165 by Adults With PKU (Prism-2)

Phenylketonuria (PKU)

United States
University of British Columbia
Rare Disease Foundation, Vancouver, Canada

Completed

Simple Breath Test to Examine Phenylalanine Metabolism

Phenylketonuria (PKU)

Canada
University of Colorado, Denver
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Withdrawn

Anti-IL-1 Treatment in Children Diabetic Keto-Acidosis (DKA) at Diagnosis of Type 1 Diabetes

Type I Diabetes

United States
Brendan Lee

Completed

Phenylbutyrate Therapy for Maple Syrup Urine Disease (MSUD)

Maple Syrup Urine Disease

United States

Clinical Trials on Eicosapentaenoic Acid

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Cambodia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations