Clinical Trials on End-Stage Renal Failure in Czechia

Total 348 results

B.Braun Avitum AG
Winicker Norimed GmbH

Completed

Determination In-vivo KUF for Diacap Pro Hemodialyser

Renal Insufficiency,Chronic | Kidney Insufficiency | Kidney Disease, End-Stage | Kidney Failure,Chronic

Czech Republic
Fresenius Medical Care Deutschland GmbH
Institut Dr. Schauerte GmbH (IDS)

Completed

Comparison of Clinical Performance and Hemocompatibility of Dialyzers Applied During Post-dilution Online Hemodiafiltration (eMPORAIII)

Renal Failure | End Stage Renal Disease

Germany, Czechia, Hungary
Bristol-Myers Squibb

Completed

A Study of Experimental Medication BMS-986231 in Patients With Different Levels of Kidney Function

Renal Failure | Congestive Heart Failure | Kidney Failure | Cardiac Failure | Myocardial Failure

Poland, Czechia
Astellas Pharma Europe B.V.
FibroGen

Completed

Roxadustat in the Treatment of Anemia in End Stage Renal Disease (ESRD) Patients on Stable Dialysis (Pyrenees)

Anemia | End Stage Renal Disease (ESRD)

Bulgaria, Croatia, Czechia, Germany, Hungary, Poland, Russian Federation, Serbia, Spain, United Kingdom, Belgium, France, Georgia, Italy, Portugal, Romania, Slovakia
Merck Sharp & Dohme LLC

Active, not recruiting

Global Study of MK-2060 (Anti-Factor XI Monoclonal Antibody) in Participants With End Stage Renal Disease Receiving Hemodialysis (FXI Hemodialysis Study) (MK-2060-007)

Kidney Failure, Chronic | End-Stage Renal Disease | End-Stage Kidney Disease

United States, Argentina, Australia, Brazil, Bulgaria, Canada, Czechia, Germany, Greece, Italy, Portugal, Puerto Rico, Romania, Russian Federation, Sweden
University Hospital Ostrava

Not yet recruiting

Determination of Drug Levels for Pharmacotherapy of Heart Failure

Cardiovascular Diseases | Heart Failure With Reduced Ejection Fraction

Czechia
Daiichi Sankyo, Inc.
PRA Health Sciences

Completed

Pilot PK/PD Study of DS-1093a in Patients With Chronic Kidney Disease

Chronic Renal Disease | Renal Anemia

Czechia, Hungary
Charles University, Czech Republic
Ministry of Health, Czech Republic

Unknown

Metabolic Aspects of Citrate Anticoagulation in Renal Replacement Therapy (Citrate)

Critical Illness | Acute Renal Failure

Czech Republic
Masaryk Memorial Cancer Institute

Completed

Adjuvant Partial-breast Irradiation Using Stereotactic Body Radiation Therapy

Early-stage Breast Cancer

Czechia
Bayer

Completed

Factor XI LICA to Reduce Events Such as Heart Attack and Stroke in Patients Whose Kidneys Are no Longer Able to Work as They Should and Require Treatment to Filter Wastes From the Blood: Focus is on the Safety of BAY2976217 and the Way the Body Absorbs, Distributes and Removes the Study Drug (RE-THINc ESRD)

End Stage Renal Disease Requiring Hemodialysis

Belgium, United States, Latvia, Taiwan, Germany, Japan, Spain, Canada, Bulgaria, Greece, Ukraine, Czechia, Hungary, Korea, Republic of, Russian Federation
Novartis Pharmaceuticals

Completed

Evaluation of Renal Function Impairment on the Pharmacokinetics of LEE011

Impaired Renal Function | Normal Renal Function

United States, Germany, Bulgaria, Czechia
Novartis Pharmaceuticals

Completed

Advancing Renal TRANSplant eFficacy and Safety Outcomes With an eveRolimus-based regiMen (TRANSFORM) (TRANSFORM)

Hemodialysis | Renal Replacement Therapy | End Stage Renal Disease (ESRD) | Renal Transplantation | Chronic Kidney Disease (CKD)

Germany, United States, Belgium, Italy, Spain, Croatia, Taiwan, Australia, Austria, Greece, Korea, Republic of, Lebanon, Czechia, Israel, Netherlands, Slovenia, Switzerland, Thailand, Norway, Turkey, Sweden, Argentina, Brazil, Japan, Se... and more
Calliditas Therapeutics AB

Completed

The Effect of Nefecon® in Patients With Primary IgA Nephropathy at Risk of Developing End-stage Renal Disease (NEFIGAN)

Primary IgA Nephropathy

Belgium, United Kingdom, Denmark, Finland, Sweden, Germany, Spain, Italy, Czech Republic, Netherlands
Fresenius Medical Care Deutschland GmbH

Completed

PD-Improved Dialysis Efficiency With Adapted APD (PD-IDEA)

Chronic Renal Failure

Spain, Sweden, Finland, Czechia, Denmark, Malaysia
Idorsia Pharmaceuticals Ltd.

Completed

A Study to Evaluate ACT-132577 in Healthy Subjects and in People With Severe Kidney Disease

Healthy Subjects | Severe Renal Impairment

Czechia
Charles University, Czech Republic
Brno University Hospital; University Hospital Olomouc; Tomas Bata Hospital, Czech... and other collaborators

Unknown

Pedometer-Based Walking Intervention in Patients With Chronic Heart Failure With Preserved Ejection Fraction

Diastolic Heart Failure

Czechia
University Hospital Ostrava

Active, not recruiting

The Use of Blood Biochemical Markers for Diagnostics of Heart Muscle Diseases

Heart Failure | Left Ventricular Hypertrophy | Heart Dilation

Czechia
Charles University, Czech Republic
Brno University Hospital; University Hospital Olomouc; Tomas Bata Hospital, Czech... and other collaborators

Active, not recruiting

Pedometer-Based Walking Intervention in Patients With Chronic Heart Failure With Reduced Ejection Fraction

Systolic Heart Failure

Czechia
Masaryk University
Masaryk Memorial Cancer Institute

Recruiting

The Effectiveness of Psychological Interventions in Psycho-neuroendocrine-immune Network in Breast Cancer Survivors

Breast Cancer Stage I | Breast Cancer Stage II | Breast Cancer Female | Breast Cancer Stage III

Czechia
Fresenius Kabi
EastHORN Clinical Services in CEE; MLM Medical Labs GmbH; ALS Czech Republic,... and other collaborators

Completed

Short-term Metabolic Effects of Ketosteril® Supplemented Low Protein Diet in Pre-dialysis Chronic Kidney Disease (CKD) Patients (CKD)

Renal Insufficiency, Chronic

Czechia
Bayer

Completed

Study to Investigate the Safety of a Drug Called Osocimab at Low and High Doses in Adult Patients With Kidney Failure Requiring Regular Hemodialysis (CONVERT)

Hemodialysis | End-stage Renal Disease | Hemodiafiltration | Prevention of Thromboembolic Events

Spain, Greece, Belgium, Russian Federation, Netherlands, Turkey, Japan, Australia, Austria, Bulgaria, Italy, Ukraine, Czechia, Israel, United States, Hungary, Lithuania, Poland, Portugal
University Hospital Ostrava

Completed

Cardiac Strains for Optimization of CRT in Non-Responders

Chronic Heart Failure

Czechia
University Hospital, Motol

Completed

Intravenous Continuous LMWH Seems to be Safe Alternative to UFH in VV ECMO Patients

Refractory Respiratory Failure

Czechia
Affymax
Takeda

Completed

Safety and Efficacy of Peginesatide for the Treatment of Anemia in Participants With Chronic Renal Failure Not on Dialysis (PEARL 2)

Anemia | Chronic Kidney Disease | Chronic Renal Failure

United States, Bulgaria, United Kingdom, Czech Republic, Germany, Hungary, Italy, Poland, Puerto Rico, Romania
University Hospital Ostrava

Completed

Development of Antibodies Against Transplant Kidney After Infection

Kidney Failure | Acute Infection

Czechia
Fresenius Medical Care Deutschland GmbH

Completed

Initiative for Patient Outcomes in Dialysis - Peritoneal Dialysis (PD) (IPOD-PD Study) (IPOD-PD)

Chronic Renal Failure

Spain, Korea, Republic of, Denmark, Finland, Netherlands, Belgium, United Kingdom, Turkey, France, Italy, Estonia, Sweden, Czech Republic, Austria, Bosnia and Herzegovina, Brazil, Croatia, Cuba, Germany, Greece, India, Israel, Latvia, Lithuani... and more
Heidelberg University
Baxter Healthcare Corporation; Boehringer Ingelheim; Aventis Pharmaceuticals; European...

Completed

Effect of Strict Blood Pressure Control and ACE-Inhibition on Progression of Chronic Renal Failure in Pediatric Patients (ESCAPE)

Hypertension | Children | Chronic Renal Failure | Acquired Kidney Disease | Congenital Kidney Disease

Czech Republic, France, Germany, Hungary, Italy, Lithuania, Poland, Portugal, Serbia, Sweden, Switzerland, Turkey
Noblewell
Coridea; Axon Therapies

Completed

Surgical Resection of the Greater Splanchnic Nerve in Subjects Having Heart Failure With Preserved Ejection Fraction

Heart Failure With Preserved Ejection Fraction

Czechia, Poland
Axon Therapies, Inc.

Enrolling by invitation

Endovascular GSN Ablation in Subjects With HFpEF

Heart Failure With Preserved Ejection Fraction

Czechia, Georgia
Amgen

Completed

Bone Biopsy Study For Dialysis Patients With Secondary Hyperparathyroidism of End Stage Renal Disease (BONAFIDE)

Secondary Hyperparathyroidism

United States, Italy, Belgium, Switzerland, Hungary, Spain, Turkey, Poland, Portugal, United Kingdom, Czech Republic, Macedonia, The Former Yugoslav Republic of
Hoffmann-La Roche

Completed

An Observational Study of Mircera (Methoxy Polyethylene Glycol-epoetin Beta) in Patients With Chronic Kidney Disease Not On Dialysis

Kidney Disease, Chronic

Czechia
Abbott
Massachusetts General Hospital; Harvard University

Terminated

The PRIMO II Study: Paricalcitol Injection Benefits in Renal Failure Induced Cardiac Morbidity in Subjects With Chronic Kidney Disease (CKD) Stage 5 (PRIMO II)

Hypertrophy, Left Ventricular | Chronic Kidney Disease (CKD) Stage 5

Italy, United States, Taiwan, Poland, United Kingdom, Greece, Germany, Russian Federation, Spain, Australia, Czech Republic, Puerto Rico, Romania
Institute for Clinical and Experimental Medicine

Completed

Cardioprotective and Metabolic Effects of Metformin in Patients With Heart Failure and Diabetes (CARMET)

Insulin Resistance | Chronic Heart Failure

Czechia
University Hospital, Motol

Recruiting

Eicosanoids in Human Heart Failure

Heart Failure

Czechia
University Hospital Olomouc

Completed

Advanced Telemonitoring of Patients With Heart Failure in Home Environment

Heart Failure

Czechia
The Institute of Molecular and Translational Medicine...

Not yet recruiting

Exhaled Breath Condensate Analysis in Mechanically Ventilated Patients

Critical Illness | Acute Respiratory Failure

Czechia
Institute for Clinical and Experimental Medicine

Recruiting

Exogenous Ketones for Acutely Decompensated HEart Failure (KADHEF)

Ketosis | Acute Heart Failure | Hemodynamic Instability | Low Cardiac Output Syndrome

Czechia
Allecra

Completed

Pharmacokinetics of Cefepime and AAI101 in Subjects With Renal Insufficiency and Healthy Subjects

PK in Patients With Various Degrees of Renal Impairment

Czechia, Hungary
Bristol-Myers Squibb

Completed

Belatacept Evaluation of Nephroprotection and Efficacy as First-line Immunosuppression (BENEFIT) (BENEFIT)

Kidney Transplantation | Chronic Kidney Failure

United States, Argentina, Australia, Germany, Italy, South Africa, Spain, Brazil, Mexico, Belgium, France, Hungary, Switzerland, India, Canada, Austria, Czech Republic, Poland, Israel, Sweden, Turkey
Vascular surgery, University hospital Královské...
Belfast Health and Social Care Trust

Active, not recruiting

Validation of Arterio Venous Access Stage (AVAS) Classification (VAVASC)

Arteriovenous Fistula | Kidney Failure | Arteriovenous Graft | Dialysis Access Malfunction | Dialysis Related Complication

Czechia
Institute for Clinical and Experimental Medicine

Recruiting

Landiolol for Rate Control in Decompensated Heart Failure Due to Atrial Fibrillation (LARISA)

Atrial Fibrillation | Acute Heart Failure | Left Ventricular Dysfunction | Atrial Fibrillation Rapid

Czechia
University Hospital Ostrava

Completed

The Influence of Nursing Technique Applied at the Central Venous Catheter Insertion Site Upon the Incidence of Infection

Surgery | Multiorgan Failure | Haematologic Disease

Czechia
Vojtech Melenovsky, MD, PhD

Not yet recruiting

Metabolic Response to Iniciation of Heart Failure Therapy (GliF)

Heart Failure

Czechia
Institute for Clinical and Experimental Medicine
Abbott

Unknown

Anti-thrombotic Monotherapy With the HeartMate 3 LVAS

Cardiovascular Diseases | Heart Failure

Czechia
Institute for Clinical and Experimental Medicine
Abbott

Unknown

Anti-thrombotic Monotherapy in HeartMate 3 Left Ventricular Assist System (LVAS)

Cardiovascular Diseases | Heart Failure

Czechia
Brno University Hospital
Masaryk University

Recruiting

Negative Pressure Ventilation in Paediatric Patients During Weaning (NEGWEAN)

Weaning Failure

Czechia
Takeda

Completed

A Study to Evaluate the Effect of Renal Impairment and Dialysis Treatment on the Pharmacokinetics (PK) of a Single Intravenous (IV) TAK-954

Renal Impairment | Healthy Volunteers

Czechia, Hungary
Novartis Pharmaceuticals

Completed

Pharmacokinetic Study of Buparlisib in Subjects With Renal Impairment.

Renal Impairment

Czechia, Germany, Romania, Bulgaria
University Hospital Ostrava

Recruiting

MAnual Lymphatic DrAinage to iMprove the outcomE of Patients After Septic Shock (MADAME)

Sepsis | Septic Shock | Inflammatory Response | Multiorgan Failure

Czechia
GlaxoSmithKline

Completed

Study to Assess the Safety and PK of GSK573719 and GSK573719/GW642444(VI) Combination in Healthy Subjects and Subjects With Severe Renal Impairment

Pulmonary Disease, Chronic Obstructive

Czechia, Hungary

Clinical Trials on End-Stage Renal Failure in Czechia

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