Clinical Trials on Endothelial Dysfunction

Total 7187 results

Roberta Ballard
Mallinckrodt; ONY

Completed

Trial of Late Surfactant to Prevent BPD: A Pilot Study in Ventilated Preterm Neonates Receiving Inhaled Nitric Oxide (TOLSURFPilot)

Bronchopulmonary Dysplasia | Respiratory Distress Syndrome of Prematurity (Surfactant Dysfunction)

United States
National Institute of Mental Health (NIMH)

Terminated

Mild Neurocognitive Disorder in HIV Infection of the Brain

HIV-Associated Cognitive Motor Complex

United States
University of Zurich
Swiss National Science Foundation; Balgrist University Hospital

Completed

Supraspinal Control of Lower Urinary Tract Function in Healthy Controls and Patients With Bladder Dysfunction

Multiple Sclerosis | Overactive Bladder | Spinal Cord Injury | Neurogenic Lower Urinary Tract Dysfunction

Switzerland
Pamlab, Inc.
InfoMedics, Inc.

Completed

NAC-003 P.L.U.S. Program (Progress Through Learning Understanding & Support)

Mild Cognitive Impairment | Vascular Dementia | Alzheimer's Disease | Early Memory Loss

United States
Edwards Lifesciences

Completed

COMPASSION - COngenital Multicenter Trial of Pulmonic VAlve Regurgitation Studying the SAPIEN InterventIONal THV

Pulmonary Valve Insufficiency | Pulmonary Regurgitation | Pulmonary Stenosis | Dysfunctional RVOT Conduit | Pulmonary Obstruction

United States
University of Bern

Recruiting

Swiss Paediatric Airway Cohort (SPAC)

Cough | Asthma | Dysfunctional Breathing | Wheezing | Exercise Induced Bronchospasm | Inspiratory Laryngeal Obstruction

Switzerland, Austria
University Hospital, Ghent
Medtronic

Completed

OptiLUTS Part C: The Development of a Symptom Assessment Tool in Sacral Neuromodulation. (OptiLUTS)

Urinary Retention | Fecal Incontinence | Overactive Bladder Syndrome | Dysfunctional Voiding | Fowler Syndrome

Belgium
Milton S. Hershey Medical Center

Terminated

Study of Conventional Laparoscopic Hysterectomy Versus Robot-Assisted Laparoscopic Hysterectomy at a Teaching Institution

Endometriosis | Pelvic Pain | Leiomyoma | Menorrhagia | Dysfunctional Uterine Bleeding

United States
University of Texas at Austin
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Effects of Early Abuse on Adult Intimate Relationships

Major Depressive Disorder | Post-traumatic Stress Disorder | Hypoactive Sexual Desire Disorder | Female Orgasmic Disorder | Female Sexual Arousal Disorder

United States
Fenway Community Health
Patient-Centered Outcomes Research Institute; Callen-Lorde Community Health...

Unknown

Transgender Cohort Study of Gender Affirmation and HIV-related Health

HIV/AIDS | Gender Dysphoria | Depression, Anxiety | STI | Gender Identity | Transsexualism

United States
Lviv National Medical University

Recruiting

Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal Deformations (BBESPB)

Nutrition Disorders | Chronic Pain | Postoperative Pain | Anesthesia, Local | Postoperative Cognitive Dysfunction | Scoliosis | Coagulation Disorder | Acute Pain | Neuropathic Pain | Anesthesia | Postoperative Nausea and Vomiting | Ventilator-Induced Lung Injury | Intraoperative Complications | Hyperalgesia | Regional... and other conditions

Ukraine
University Health Network, Toronto

Not yet recruiting

RCT of Gut-directed Hypnotherapy in Ehlers-Danlos Syndromes and Generalized Hypermobility Spectrum Disorders

Irritable Bowel Syndrome | Gastrointestinal Dysfunction | Ehlers-Danlos Syndrome | Hypermobility Syndrome

Canada
Montefiore Medical Center

Terminated

The Impact of Sexual Health and Amputation Focused Education on Regulation of Glucose and Amputation Prevention

Sexual Dysfunction | Amputation; Traumatic, Limb | Diabetic Ulcers on Both Feet | Diabetic Foot Ulcer Ischemic

United States
Hamad Medical Corporation

Completed

Renal Involvement in Hospitalized Children With COVID-19 (RIHCC)

Coronavirus Infection | Covid19 | Renal Insufficiency | AKI | Acute Kidney Injury | Pediatric Kidney Disease | Renal Dysfunction

Qatar
Brigham and Women's Hospital

Completed

Network Modulation in Alzheimer's Disease

Alzheimer Disease | Mild Cognitive Impairment | Primary Progressive Aphasia

United States
Wake Forest University Health Sciences

Completed

Pioglitazone Hydrochloride in Preventing Radiation-Induced Cognitive Dysfunction in Treating Patients With Brain Tumors

Glioblastoma Multiforme | Anaplastic Astrocytoma | Brain Neoplasms, Benign | Brain Neoplasms, Malignant | Malignant Meningioma

United States
Children's Cancer and Leukaemia Group

Unknown

Treatment Outcome and Quality of Life in Patients With Pediatric Extra-Cranial Germ Cell Tumors Previously Treated on Clinical Trial CCLG-GC-1979-01 or CCLG-GC-1989-01

Infertility | Ovarian Cancer | Sexual Dysfunction | Neurotoxicity | Long-term Effects Secondary to Cancer Therapy in Children | Gastrointestinal Complications | Urinary Complications | Pulmonary Complications | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

Ireland, United Kingdom
Northwell Health

Recruiting

Detection of Vocal Fold Motion Impairment on Noninvasive Positive Pressure

Vocal Cord Paralysis | Vocal Cord Dysfunction | Recurrent Laryngeal Nerve Injuries | Vocal Cord Paresis | Recurrent Laryngeal Nerve Palsy

United States
University Hospital, Toulouse

Not yet recruiting

Cognitive Dysfunctions Associated With Delirium in Critically-ill ARDS Patients (DeSign)

Delirium | Acute Respiratory Distress Syndrome
Universitaire Ziekenhuizen KU Leuven

Recruiting

Multimodal Retinal Imaging in the Detection and Follow-up of Alzheimer's Disease (RetAD)

Glaucoma | Age-Related Macular Degeneration | Diabetic Retinopathy | Dementia | Alzheimer Disease | Mild Cognitive Impairment | Alzheimer Dementia

Belgium
IRCCS Centro Neurolesi "Bonino-Pulejo"

Completed

The Efficacy of VESPA 2.0 for Cognitive Rehabilitation in Patients With Mild Cognitive Impairment

Multiple Sclerosis | Neurodegenerative Diseases | Alzheimer Disease | Cognitive Decline | Parkinson Disease Dementia

Italy
Abant Izzet Baysal University

Completed

Expiratory Muscle Training in Stroke

Stroke | Stomatognathic Diseases | Dysphagia | Temporomandibular Disorders | Mastication Disorder

Turkey
Instituto Nacional de Enfermedades Respiratorias
National Council of Science and Technology, Mexico; Fundación Clínica Médica...

Completed

Effect of CPAP on Myocardial Dysfunction in Type 2 Diabetes Mellitus and Obstructive Sleep Apnea Patients

Sleep Apnea, Obstructive | Obesity | Diabetes Mellitus, Type 2 | Continuous Positive Airway Pressure | Echocardiography | Myocardial Dysfunction

Mexico
Andreas Monsch

Completed

Normative Values for the German Version of the Montreal Cognitive Assessment (MoCA) (MoCA-Norm)

Cognitive Impairment | Dementia | Cognitive Change | Cognition Disorders | Cognitive Decline | Dementia, Alzheimer Type | Cognitive Deterioration | Cognitive Symptom | Cognition Disorders in Old Age | Dementia Alzheimers | Dementia of Alzheimer Type | Cognitive Impairment, Mild | Dementia, Mild | Cognitive Abnormality
Assiut University

Completed

N-acetylcysteine for Renal Protection in Patients With Rheumatic Heart Disease Undergoing Valve Replacement

Renal Dysfunction | Cardiac Surgery for Rheumatic Valvular Heart Disease

Egypt
Assiut University

Not yet recruiting

Evaluation of Cognitive Dysfunction and Psychiatric Comorbidities

Wilson Disease
St. Joseph's Hospital and Medical Center, Phoenix
Texas Tech University

Not yet recruiting

MCLENA-2: A Phase II Clinical Trial for the Assessment of Lenalidomide in Patients With Mild Cognitive Impairment Due to Alzheimer's Disease

Cognitive Dysfunction | Neurodegenerative Disease, Hereditary | Cognitive Impairment, Mild | Amyloid Plaque | Inflammation, Brain
Indiana University
National Heart, Lung, and Blood Institute (NHLBI); University of California... and other collaborators

Not yet recruiting

SHADES Mechanistic Trial (SHADES)

Heart Diseases | Cardiovascular Diseases | Coronary Artery Disease | Stroke | Sleep Disorder | Insomnia | Sleep Disturbance | Metabolic Disease | Autonomic Dysfunction | Insomnia Chronic | Systemic Inflammatory Response | Insomnia, Primary

United States
Washington University School of Medicine
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D) (Metabrain)

Inflammation | Insulin Resistance | Type 2 Diabetes Mellitus in Obese | Obesity, Childhood | Type2 Diabetes | Cognitive Decline | Dysglycemia | Overweight, Childhood | Brain Structure | Microvascular Complications | Diabetes in Adolescence

United States
NHS Greater Glasgow and Clyde
Abbott Medical Devices; University of Glasgow

Recruiting

iCorMicA - Stratified Medicine in Angina (iCorMicA)

Coronary Artery Disease | Angina, Stable | Microvascular Angina | Vasospastic Angina | Coronary; Ischemic | Non-Obstructive Coronary Atherosclerosis | Ischemia With No Obstructive Coronary Arteries (INOCA) | Coronary Microvascular Dysfunction (CMD) | Ischaemic Heart Disease | Angina Attacks

United Kingdom
Centre Integre Universitaire de Sante et Services...

Active, not recruiting

Use of Point-of-care Neuro-sacral Electrophysiology Following Spinal Cord Injury

Spinal Cord Injuries | Neurogenic Bowel | Neurogenic Bladder Dysfunction

Canada
Western Kentucky University
National Institute on Aging (NIA)

Completed

Bingocize: A Novel Mobile Application for Older Adult Health (Bingocize)

Arteriosclerosis | Hypertension | Diabetes Mellitus, Type 2 | Sarcopenia | Executive Function | Cognitive Decline | Activities of Daily Living | Accidental Fall | Cognitive Aging

United States
University of Texas Southwestern Medical Center
Texas A&M University; University of Texas Rio Grande Valley

Completed

PST for Care Partners of Adults With Alzheimer's and Alzheimer'S-related Dementia

Mild Cognitive Impairment (MCI) | Alzheimer Disease | Lewy Body Dementia (LBD) | Frontotemporal Degeneration (FTD) | Vascular Contributions to Cognitive Impairment and Dementia (VCID) | Mixed Etiology Dementias (MED)

United States
Tanta University

Enrolling by invitation

Role of Silymarin in Chemotherapy Toxicity and Cognition Improvement in Breast Cancer Patients

Breast Cancer | Cognitive Impairment | Peripheral Neuropathy | Cardiac Toxicities | Hepatic Toxicity

Egypt
Aga Khan University Hospital, Pakistan

Completed

Relationship Between Serum 1,25-dihydroxy Vitamin D and Markers of Bone Metabolism in Renal Dysfunction Patients

Chronic Kidney Disease-Mineral and Bone Disorder
Rachel Miller
Office of US Army Medical Research and Material Command

Completed

Chemotherapy-Induced Cognitive Impairment in Ovarian Cancer Patients

Chemotherapy-induced Cognitive Impairment

United States
Cambridge Respiratory Innovations Limited
Innovate UK

Completed

The General Breathing Record Study (GBRS)

Heart Failure | Pneumonia | Motor Neuron Disease | Asthma | Vocal Cord Dysfunction | Breathlessness

United Kingdom
University of North Carolina, Chapel Hill

Terminated

Temporomandibular Disorder (TMD) Pain in Response to Jaw Advancement in People With TMD and Obstructive Sleep Apnea

Myalgia | Apnea, Obstructive Sleep
King's College London

Not yet recruiting

Case Control Study to Investigate the Use of Urethral Pressure Profile Measurement in Children

Dysfunctional Voiding | Stress Incontinence, Urinary

United Kingdom
Thomas Jefferson University

Completed

Evaluating Drug Interactions Between Doravirine With Estradiol and Spironolactone in Healthy Transgender Women (IDENTIFY)

Gender Dysphoria | Transgender Women | Transgender Health | Human Immunodeficiency Virus

United States
Skane University Hospital
Lund University

Recruiting

The Swedish BioFINDER - Memory Clinic Study (Validate)

Alzheimer Disease | Frontotemporal Degeneration | Mild Cognitive Impairment | Lewy Body Disease | Vascular Dementia | SCD | Mild Dementia

Sweden
Universitaire Ziekenhuizen KU Leuven

Not yet recruiting

Correlation Pelvic Floor Function and Ultrasound Findings One Year After Childbirth (DeliverUU)

Urinary Incontinence | Constipation | Sexual Dysfunction | Pelvic Organ Prolapse | Pelvic Pain | Pelvic Floor Disorders | Anal Sphincter Injury | Anal Incontinence | Obstetric Trauma
Silesian Centre for Heart Diseases
Medical Research Agency, Poland

Not yet recruiting

Sacubitril/Valsartan in PriMAry preventIoN of the Cardiotoxicity of Systematic breaST canceR trEAtMent (MAINSTREAM)

Heart Failure | Breast Cancer | Breast Diseases | Cardiotoxicity | Molecular Mechanisms of Pharmacological Action | Angiotensin Receptor Antagonists | Neoplasm, Breast | Cardiac Toxicity | Angiotensin II Type 1 Receptor Blockers | Cancer, Therapy-Related | Antihypertensive Agents | Sacubitril/Valsartan | Cancer...

Poland
Ciusss de L'Est de l'Île de Montréal
Covid-19 Early Treatment Fund

Not yet recruiting

Cyproheptadine in Severe COVID-19 : A Unblinded Randomized Trial

Serotonin Syndrome | Platelet Dysfunction | Viral Pneumonia
Skane University Hospital
Lund University

Active, not recruiting

The Swedish BioFINDER Study

Mild Cognitive Impairment | Vascular Dementia | Alzheimer's Disease | Dementia With Lewy Bodies

Sweden
Children's Hospital Medical Center, Cincinnati

Completed

Eculizumab to Treat Thrombotic Microangiopathy/Atypical Hemolytic Uremic Syndrome -Associated Multiple Organ Dysfunction Syndrome in Hematopoietic Stem Cell Transplant Recipients

Thrombotic Microangiopathies | Atypical Hemolytic Uremic Syndrome | Multiple Organ Dysfunction Syndrome

United States
Cognito Therapeutics, Inc.

Active, not recruiting

Study of Tolerability, Safety and Efficacy of Sensory Stimulation at Multiple Dose Levels to Improve Brain Function (Etude Study)

Cognitive Impairment | Alzheimer Disease | Mild Cognitive Impairment | Cognitive Decline | Alzheimer Disease, Early Onset | Alzheimer Disease, Late Onset | Dementia, Alzheimer Type | Memory Disorders | Memory Impairment | Alzheimer Dementia | Memory Loss | Dementia, Mild | Memory Disorders, Age Related

United States
Skane University Hospital
Lund University

Recruiting

The Swedish BioFINDER - Primary Care Study (ADetect)

Alzheimer Disease | Frontotemporal Degeneration | Mild Cognitive Impairment | Lewy Body Disease | Vascular Dementia | SCD | Mild Dementia

Sweden
Target PharmaSolutions, Inc.

Not yet recruiting

An Observational Study of Patients Living With Chronic Neurological Diseases

Multiple Sclerosis | Parkinson Disease | Alzheimer Disease | Mild Cognitive Impairment | Dementia of Alzheimer Type | Neurological Diseases or Conditions
Daping Hospital and the Research Institute of Surgery...
Children's Hospital of Chongqing Medical University

Recruiting

Surfactant for Neonatal Respiratory Distress Syndrome(NRDS) and Neonatal Acute Respiratory Distress Syndrome(NARDS)

Preterm Birth | Acute Respiratory Distress Syndrome | Respiratory Distress Syndrome | Surfactant Dysfunction

China

Clinical Trials on Endothelial Dysfunction

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CROs in Turkmenistan

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