Clinical Trials on Epileptic Seizures

Total 1132 results

Eisai Inc.

Completed

A Post-marketing Observational Study Of The Use Of Zonisamide (ZNS) in the Adjunctive Treatment Of Adult Patients With Partial Onset Seizures (Study E2090-E044-410) (ZOOM)

Partial Onset Seizures

Germany, Sweden, Norway, Austria, Denmark
University of Manitoba

Completed

Treating Non-epileptic Seizures Using Magnetic Brain Stimulation

Nonepileptic Seizures
UCB Pharma

Completed

A Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel Group Trial to Investigate the Efficacy and Safety of SPM 927 (200mg/Day and 400mg/Day) as Adjunctive Therapy in Subjects With Partial Seizures With or Without Secondary Generalization

Partial Seizures With or Without Secondary Generalization

Germany
Children's Hospital of Fudan University

Completed

The Prevalence and Risk Factors of Coagulopathy in Pediatric Epilepsy Surgery Patients

Epilepsy; Seizure | Epilepsy in Children | Coagulation and Hemorrhagic Disorders | Antiepileptic Adverse Reaction

China
Eisai Inc.

Terminated

Open-Label Extension Study of Rufinamide Given as Adjunctive Therapy in Patients With Refractory Partial Seizures

Refractory Partial Onset Seizures

United States
Eisai Limited

Terminated

Adjunctive Zonisamide in Primary Generalised Tonic Clonic Seizures

Epilepsy

Australia, Serbia, Germany, Czech Republic, Romania, Estonia, Lithuania, Croatia, Finland, Hungary, Poland, Russian Federation, Ukraine
Eisai Inc.

Completed

A Post-marketing Study Evaluating Eslicarbazepine Acetate (ESL) as Adjunctive Treatment in Partial-Onset Seizures (Study E2093-E044-404) (EPOS)

Partial Onset Seizures

France, United Kingdom, Germany, Denmark, Czech Republic, Norway, Sweden, Ireland
King Abdullah International Medical Research Center

Completed

Replacing Protein Via Enteral Nutrition in a Stepwise Approach in Critically Ill Patients (Replenish)

Critical Illness | Septic Shock | Hemorrhagic Shock | Multiple Trauma | ARDS | Seizure Disorder

Saudi Arabia
Assiut University

Not yet recruiting

Inflammatory Biomarkers in Seizure (seizure)

Biomarkers in Seizures
Epilepsy Foundation of America

Recruiting

Epilepsy Learning Healthcare System (ELHS) (ELHS)

Epilepsy | Neurologic Disorder | Rare Diseases | Seizure Disorder

United States
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Stress and Seizures - Can a Brief Self-help Book Help?

Epilepsy | Dissociative Seizures

United Kingdom
Eisai Inc.

Completed

A Study to Evaluate the Safety and Efficacy of Zonisamide an Antiepileptic Drug as Monotherapy or Adjunctive Therapy in Treatment of Adult Patients With Partial, Generalized or Combined Seizures.

Partial, Generalized and Combined Seizures

India
Neurocrine Biosciences

Completed

Efficacy, Safety, Tolerability, and Pharmacokinetics of NBI-827104 in Pediatric Subjects With Epileptic Encephalopathy With Continuous Spike-and-Wave During Sleep

Epileptic Encephalopathy | Continuous Spike and Wave During Sleep

United States, Denmark, Spain, Switzerland, United Kingdom, Canada
Jazz Pharmaceuticals

Terminated

Efficacy and Safety of GWP42003-P Oral Solution in Children With Epilepsy With Myoclonic-atonic Seizures

Seizures Associated With EMAS

United States, Italy
Tanta University

Completed

Comparison Between Melatonin and Diazepam for Prevention of Recurrent Simple Febrile Seizures

Febrile Seizures

Egypt
Longboard Pharmaceuticals

Completed

Study to Investigate LP352 in Subjects With Developmental and Epileptic Encephalopathies (PACIFIC)

Dravet Syndrome | Lennox Gastaut Syndrome | Developmental and Epileptic Encephalopathy

United States, Australia
Sara Varea

Completed

Perioperative Magnesium Sulphate as a Cerebral Protector in Neurosurgical Patients (MAGNA)

Brain Tumor | Seizures (Incl Subtypes)

Spain
Great Ormond Street Hospital for Children NHS Foundation...
Karolinska University Hospital; University College London Hospitals; Helsinki... and other collaborators

Completed

NEMO1:NEonatal Seizure Using Medication Off-patent (NEMO1)

Neonatal Seizures

United Kingdom, Sweden, Ireland, Netherlands
Hospices Civils de Lyon

Recruiting

Evaluation of Tibial Nerve Selective Neurotomy Compared to Botulinum Toxin Injections for Spastic Foot Treatment in Post-stroke Patients According to a Goal-centered Approach (FOOTNEUROTOX)

Spastic Foot | Post Stroke Seizure

France
University of Florida

Completed

1 Week Versus 6 Weeks of Levetiracetam in Surgical Brain Tumor Patients

Brain Neoplasms | Brain Cancer | Brain Tumors | Seizure | Cancer of the Brain | Cancer of Brain

United States
University of Twente
Radboud University Medical Center; University Medical Center Groningen; Maastricht... and other collaborators

Completed

TELSTAR: Treatment of ELectroencephalographic STatus Epilepticus After Cardiopulmonary Resuscitation (TELSTAR)

Cardiac Arrest | Status Epilepticus | Anoxic Encephalopathy

Netherlands, Belgium
Longboard Pharmaceuticals

Recruiting

Open-label, Long-term Safety Study of LP352 in Subjects With Developmental and Epileptic Encephalopathy

Dravet Syndrome | Lennox-Gastaut Syndrome | Developmental and Epileptic Encephalopathy

United States, Australia
Longboard Pharmaceuticals

Available

Intermediate-Size Expanded Access Protocol (EAP) for LP352

Dravet Syndrome | Lennox Gastaut Syndrome | Developmental and Epileptic Encephalopathies

United States
Dartmouth-Hitchcock Medical Center

Withdrawn

Vaping-Related Seizures - A Prospective Study

Evaluate the Association of Vaping With Seizures

United States
University of North Carolina, Chapel Hill
Focused Ultrasound Foundation

Recruiting

A Pilot Study: Focused Ultrasound Thalamotomy for the Prevention of Secondary Generalization in Focal Onset Epilepsy

Partial Seizures With Secondary Generalization

United States
Mazandaran University of Medical Sciences

Completed

Levetiracetam Versus Valproate in Idiopathic Generalized Tonic-clonic Seizures

Epilepsy, Idiopathic Generalized

Iran, Islamic Republic of
Eisai Limited

Completed

A Study to Investigate Dosage, Effectiveness, and Safety of Perampanel When Used as First Add-on Therapy in Participants >=12 Years With Partial Onset Seizures With or Without Secondary Generalization or With Primary Generalized Tonic-Clonic Seizures Associated With Idiopathic Generalized Epilepsy

Idiopathic Generalized Epilepsy | Partial Onset Seizures | Generalised Tonic-Clonic Seizures

France, Spain, Italy, Denmark, Germany, Portugal, Russian Federation
Neurocrine Biosciences

Enrolling by invitation

Extension Study to Evaluate NBI-827104 in Pediatric Participants With Epileptic Encephalopathy With Continuous Spike-and-Wave During Sleep (Steamboat 2)

Epileptic Encephalopathy | Continuous Spike and Wave During Sleep

United States, Denmark, Spain, Switzerland, United Kingdom
Zogenix, Inc.
Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc.

Active, not recruiting

A Study to Investigate the Long-Term Safety of ZX008 (Fenfluramine Hydrochloride) Oral Solution in Children and Adults With Epileptic Encephalopathy Including Dravet Syndrome and Lennox-Gastaut Syndrome

Dravet Syndrome | Epileptic Encephalopathy | Lennox Gastaut Syndrome

United States, Australia, Belgium, Canada, Denmark, France, Germany, Italy, Mexico, Netherlands, Poland, Spain, Sweden, United Kingdom
University of Rochester
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

A Safety and Feasibility Study of Enteral LVT vs. Standard of Care for Seizure Control in Pediatric CM (LVT2)

Epilepsy | Seizure | Cerebral Malaria

Malawi
UCB Biopharma SRL

Enrolling by invitation

A Study to Test the Safety/ Efficacy of Brivaracetam (BRV) Used as Adjunctive Treatment in Subjects >=16 Years of Age With Partial Seizures With or Without Secondary Generalization

Epilepsy | Partial Seizures With or Without Secondary Generalization

China, Japan
University of Saskatchewan

Active, not recruiting

Cannabidiol in Children With Refractory Epileptic Encephalopathy (CARE-E)

Epileptic Encephalopathy

Canada
Eisai Inc.

Completed

E2007 Given as Adjunctive Therapy in Patients With Refractory Partial Seizures

Epilepsy

United States
Biolert

Completed

Study of Algorithm for Epilepsy Alert Device

Motor Seizures
University of Rochester
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Enteral Levetiracetam For Seizure Control In Pediatric Cerebral Malaria (LVT1)

Epilepsy | Seizure | Cerebral Malaria

Malawi
UCB Biopharma SRL

Completed

A Study to Evaluate the Efficacy and Safety of Brivaracetam in Study Participants (>=16 to 80 Years of Age) With Epilepsy

Epilepsy | Partial Seizures With or Without Secondary Generalization

China, Japan, Malaysia, Philippines, Singapore, Taiwan, Thailand
UCB Biopharma S.P.R.L.

Completed

A Study to Evaluate the Safety and Tolerability of Intravenous Brivaracetam (BRV) as Replacement for Oral Brivaracetam in Japanese Subjects >=16 Years of Age With Partial Seizures With or Without Secondary Generalization

Epilepsy | Partial Seizures With or Without Secondary Generalization

Japan
Cambridge University Hospitals NHS Foundation Trust
Norfolk and Norwich University Hospitals NHS Foundation Trust; Luton and Dunstable... and other collaborators

Recruiting

EAGLET: EEG vs aEEG to Improve the Diagnosis of neonataL Seizures and Epilepsy (EAGLET)

Neonatal Seizures

United Kingdom
Whanin Pharmaceutical Company

Completed

Clinical Trial for Zebinix (Eslicarbazepine Acetate) in Healthy Korean and Caucasian Adult

Partial-onset Seizures With or Without Secondary Generalisation

Korea, Republic of
UCB Pharma SA

Completed

Open-label, Randomized, Active-controlled Study of LEV Used as Monotherapy in Patients With Partial-Onset Seizures

Epilepsy | Partial Seizures

China
Cairo University

Unknown

Efficacy of Levetiracetam in Control of Neonatal Seizures Guided by an EEG

Neonatal Seizures

Egypt
Eisai Inc.

Completed

Assessing The Long-Term Safety And To Explore The Long-Term Efficacy Of Zonisamide As Monotherapy In Newly Diagnosed Partial Seizures

Epilepsy

Greece, Italy, Spain, Sweden, Korea, Republic of, Germany, Australia, France, Switzerland, Slovakia, Poland, Taiwan, Hungary, Serbia, India, United Kingdom, Denmark, Russian Federation, South Africa, Montenegro
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Extension Study Of Long-Term Safety And Efficacy Of Pregabalin As Monotherapy (Lyrica) In Patients With Partial Seizures

Epilepsy

United States, Ukraine, Hong Kong, Czechia
Markus Schuelke, M.D.
University of Kiel; Ludwig-Maximilians - University of Munich; University of Ulm and other collaborators

Completed

Clinical-genetic Investigations in Children With Early Infantile Epilepsies

Epilepsy | Seizures, Infantile

Germany
Valexfarm

Completed

Remegal Different Doses in Patients With Refractory Partial Seizures

Self Efficacy | Drug Safety | Normal Drug Tolerance

Russian Federation
UCB Japan Co. Ltd.

Completed

An Open Label Study of Levetiracetam in Japanese Pediatric Patients With Partial Seizures

Epilepsy | Partial Seizures

Japan
University Hospital, Grenoble
Laboratoire de Psychologie et NeuroCognition

Completed

Cartography of Functional and Epileptic Cerebral Areas by Functional MRI and Electroencephalography in Epileptic Patients Before and After Surgery

Epilepsy
Maharashtra University of Health Sciences

Unknown

Efficacy Study of Folic Acid Supplementation in Adolescent Epileptics

Epilepsy

India
UCB Biopharma SRL

Recruiting

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Lacosamide in Neonates With Repeated Electroencephalographic Neonatal Seizures (LENS)

Epilepsy | Electroencephalographic Neonatal Seizures

United States, Australia, Canada
UCB BIOSCIENCES, Inc.

Completed

Safety and Efficacy of Lacosamide as Additional Therapy in Patients Suffering From Epileptic Tonic-Clonic Seizures (VALUE)

Epilepsy

United States, Australia, Brazil, Bulgaria, China, Czechia, France, Germany, Hungary, Israel, Italy, Japan, Korea, Republic of, Mexico, Poland, Portugal, Romania, Russian Federation, Slovakia, Spain, Taiwan

Clinical Trials on Epileptic Seizures

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Japan

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations