Clinical Trials on Epithelial-Mesenchymal Transition in Spain

Total 1121 results

Biorek S.R.L.

Recruiting

Biomarkers of Renal Cancer (BRC)

Renal Cell Carcinoma | Angiomyolipoma | Tumor, Solid | Oncocytoma

Italy, Spain
Targovax Oy
Theradex

Unknown

A Randomised Phase II Open-label Study With a Phase Ib Safety lead-in Cohort of ONCOS-102, an Immune-priming GM-CSF Coding Oncolytic Adenovirus, and Pemetrexed/Cisplatin in Patients With Unresectable Malignant Pleural Mesothelioma

To Determine Safety, Tolerability and Efficacy of ONCOS-102 in Combination With Chemotherapy

Spain, France
Miquel Angel Pavon Ribas
Catalan Institute of Health; Hospital del Mar

Recruiting

A Study to Assess the Reduction of Human Papillomavirus (HPV) Viral Infectivity and Transmission in HPV-Positive Women After Vaccination With 9vHPV (RIFT-HPV) (RIFT-HPV)

Cervical Intraepithelial Neoplasia Grade I/ II/ III (CIN I/II/III) | Human Papillomavirus (HPV) Infections | High-risk HPV | HPV-16/ 18

Spain
Regeneron Pharmaceuticals

Recruiting

Study of REGN6569 and Cemiplimab in Adult Patients With Advanced Solid Tumor Malignancies

Squamous Cell Carcinoma of Head and Neck

United States, Spain
AstraZeneca

Completed

A Phase 2 Study of Tomudex & Iressa as Second Line Chemotherapy in Subjects With Colorectal Carcinoma

Colorectal Cancer

Spain
Asociación Española de Gastroenterología
Medtronic

Completed

Usefulness of GI-GENIUS in FIT-based Colorectal Cancer Screening Program. (CADILLAC)

Gastrointestinal Neoplasms | Colorectal Neoplasms | Intestinal Neoplasms | Colorectal Cancer | Colonic Polyp | Adenoma Colon | Serrated Polyp | Serrated Adenoma

Spain
Grupo Gallego de Investigaciones Oncologicas
Amgen; Trial Form Support S.L.

Unknown

Efficacy and Safety of Panitumumab Combined With Docetaxel and Cisplatin as a First-line Treatment of Advanced Gastric or Gastroesophageal Junction Adenocarcinoma (SPIGA)

Gastric Adenocarcinoma | Gastroesophageal Junction Adenocarcinoma

Spain
Institut Català d'Oncologia
Department of Health, Generalitat de Catalunya

Recruiting

Impact of Low Muscle Mass in HNC Treated With Immunotherapy (IMMUNONUTRI)

Sarcopenia | Head and Neck Small Cell Carcinoma

Spain
Grupo Espanol Multidisciplinario del Cancer Digestivo

Completed

Study of Oxaliplatin and Sorafenib Combination to Treat Gastric Cancer Relapsed After a Cisplatin Based Treatment

Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma (Relapsed After a Cisplatin Based Treatment)

Spain
Hospital del Río Hortega

Recruiting

Brain Tumor Intraoperative Ultrasound Database (BraTioUS-DB)

Glioma | Glioblastoma | Brain Neoplasms | Brain Cancer | Brain Tumor

Italy, Spain, India
Akamis Bio

Completed

Phase I / II Study of Enadenotucirev by Sub-acute Fractionated IV Dosing in Cancer Patients (EVOLVE)

Metastatic Colorectal Cancer | Metastatic Bladder Cancer | Solid Tumours of Epithelial Origin

Belgium, Spain
UNICANCER

Active, not recruiting

Hyperthermic Intra-Peritoneal Chemotherapy (HIPEC) in Relapse Ovarian Cancer Treatment (CHIPOR)

Ovarian Epithelial Cancer Recurrent

France, Belgium, Spain
Astellas Pharma Global Development, Inc.
Merck Sharp & Dohme LLC; Seagen Inc.

Active, not recruiting

A Study of Enfortumab Vedotin Alone or With Other Therapies for Treatment of Urothelial Cancer (EV-103)

Urologic Neoplasms | Urinary Bladder Neoplasms | Carcinoma, Transitional Cell | Ureteral Neoplasms | Urothelial Cancer | Urethral Neoplasms | Renal Pelvis Neoplasms

United States, Italy, Spain, Canada, France, Puerto Rico
Neovii Biotech

Completed

Phase II Study With Catumaxomab in Patients With Gastric Cancer After Neoadjuvant CTx and Curative Resection

Gastric Cancer | Gastric Adenocarcinoma

Austria, Spain, United Kingdom, Germany
Aprea Therapeutics

Completed

p53 Activation in Platinum-Resistant High Grade Serous Ovarian Cancer, a Study of PLD With APR-246

High-grade Serous Ovarian Cancer

Spain, United Kingdom, Belgium
NovoCure GmbH

Unknown

Effect of Tumor Treating Fields (TTFields, 150kHz) Concomitant With Sorafenib For Advanced Hepatocellular Carcinoma (HCC) (HEPANOVA)

Hepatocellular Carcinoma

Italy, Czechia, France, Germany, Poland, Spain
Hospital Universitari de Bellvitge
Institut d'Investigació Biomèdica de Bellvitge

Unknown

E6/E7 mRNA Performance to Detect HSIL and Cost-effectiveness Analysis of This Screening Strategy in HIV + MSM (ELAVI-67)

Hiv | Anal Cancer | HPV - Anogenital Human Papilloma Virus Infection | HSIL, High Grade Squamous Intraepithelial Lesions

Spain
Grupo Español de Investigación en Cáncer de Ovario
Clovis Oncology, Inc.

Completed

Analysis of the Clinical Experience With Rucaparib in the Rucaparib Access Program (RAP) in Spain - A GEICO Study

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Cancer

Spain
Boehringer Ingelheim

Recruiting

A Study to Determine How BI 907828 (Brigimadlin) is Taken up in the Tumor (Phase 0) and to Determine the Highest Dose of BI 907828 (Brigimadlin) That Could be Tolerated (Phase 1a) in Combination With Radiation Therapy in People With a Brain Tumor Called Glioblastoma

Glioblastoma

Belgium, Spain, United States
Pfizer
Celgene

Completed

Dose-Escalation Study Of Palbociclib + Nab-Paclitaxel In mPDAC

Metastatic Pancreatic Ductal Adenocarcinoma

United States, Spain
Hoffmann-La Roche

Completed

A Phase Ib Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Cibisatamab in Combination With Atezolizumab After Pretreatment With Obinutuzumab in Participants With Previously Treated Metastatic Colorectal Adenocarcinoma

Colorectal Cancer

United States, France, Denmark, Spain
Odin Medical
Meditrial Europe Ltd.

Recruiting

EAGLE Trial CADDIE Artificial Intelligence Endoscopy (EAGLE)

Colorectal Cancer | Polyp of Colon | Adenoma Colon

Germany, Georgia, Italy, Poland, Spain, United Kingdom
BioInvent International AB
Merck Sharp & Dohme LLC

Recruiting

BI-1910 as a Single Agent and in Combination With Pembrolizumab for the Treatment of Advanced Solid Tumors

Hepatocellular Carcinoma | Non Small Cell Lung Cancer | Solid Tumors

Spain, Denmark, Poland, Sweden
Novartis Pharmaceuticals

Completed

A Phase I Dose Escalation Study of BKM120 With Radiation Therapy and Temozolomide in Patients With Newly Diagnosed Glioblastoma

Glioblastoma

Australia, Spain, Canada, United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Everolimus and Gefitinib in Treating Patients With Progressive Glioblastoma Multiforme or Progressive Metastatic Prostate Cancer

Prostate Cancer | Brain and Central Nervous System Tumors

United States, Spain
Genentech, Inc.

Completed

Safety and Pharmacokinetics of Escalating Doses of DNIB0600A in Participants With Non-Small Cell Lung Cancer (NSCLC) and Platinum Resistant Ovarian Cancer

Non-Small Cell Lung Cancer, Ovarian Cancer

Spain, United States
Spanish Oncology Genito-Urinary Group

Completed

Clinical Trial of Dovitinib in First-line Metastatic or Locally Advanced Non-resectable Adrenocortical Carcinoma

Adrenocortical Carcinoma

Spain
AstraZeneca
KuDOS Pharmaceuticals Limited

Completed

Study to Assess the Efficacy and Safety of a PARP Inhibitor for the Treatment of BRCA-positive Advanced Ovarian Cancer (ICEBERG 2)

Ovarian Neoplasm

United States, Spain, Australia, Germany, Sweden
Alligator Bioscience AB
Theradex; 4Pharma Ltd.

Recruiting

Safety and Efficacy of Mitazalimab in Combination With Chemotherapy in Pancreatic Cancer Patients (OPTIMIZE-1)

Metastatic Pancreatic Ductal Adenocarcinoma

France, Belgium, Spain
zr Pharma & GmbH
Foundation Medicine

Terminated

Rucaparib in Patients With Locally Advanced or Metastatic Urothelial Carcinoma (ATLAS)

Bladder Cancer | Urothelial Carcinoma | Metastatic Urothelial Carcinoma | Muscle Invasive Bladder Cancer | Ureter Carcinoma | Renal Pelvis Carcinoma | Urinary Bladder Carcinoma | Urethra Carcinoma

United States, Spain, France, Italy, Germany, United Kingdom
Janssen Research & Development, LLC

Completed

A Pivotal Bioequivalence Study of DOXIL/CAELYX (Doxorubicin HCL) in Patients With Advanced or Refractory Solid Malignancies Including Patients With Ovarian Cancer

Neoplasms | Neoplasms, Breast | Neoplasms, Ovarian | Advanced or Refractory Solid Malignancies

United States, United Kingdom, Spain, Belgium
Boehringer Ingelheim

Recruiting

A Study to Test How Well Different Doses of BI 764532 Are Tolerated by People With a Tumour in the Brain That is Positive for DLL3

Glioma

Spain, United States, Germany, Netherlands, Austria, Switzerland
BioInvent International AB

Active, not recruiting

BI-1607 in Combination With Trastuzumab in Subjects With HER2-positive Advanced Solid Tumors (CONTRAST)

HER2-positive Breast Cancer | HER2-positive Gastric Cancer | Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction Adenocarcinoma | HER2-positive Metastatic Breast Cancer

Spain, United Kingdom, Germany
Eli Lilly and Company

Completed

A Study Combining LY2157299 With Temozolomide-based Radiochemotherapy in Patients With Newly Diagnosed Malignant Glioma

Glioma

United States, Germany, Spain
Tyra Biosciences, Inc

Recruiting

Safety and Preliminary Anti-Tumor Activity of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors With FGFR3 Gene Alterations (SURF301)

Solid Tumor | Bladder Cancer | Advanced Solid Tumor | Urothelial Carcinoma | Metastatic Urothelial Carcinoma | Solid Tumor, Adult | FGFR3 Gene Mutation | Urinary Tract Cancer | Locally Advanced Urothelial Carcinoma | Advanced Urothelial Carcinoma | Non-muscle-invasive Bladder Cancer | FGFR3 Gene Alteration | Urinary... and other conditions

Australia, United States, France, Spain
Celgene

Completed

A Phase 1 Study of CC-486 as a Single Agent and in Combination With Carboplatin or ABI-007 in Subjects With Relapsed or Refractory Solid Tumors

Carcinoma, Non-Small-Cell Lung | Urinary Bladder Neoplasms | Tumor Virus Infections | Ovarian Neoplasms | Fallopian Tube Neoplasms | Peritoneal Neoplasms | Carcinoma, Transitional Cell | Carcinoma, Pancreatic Ductal

Spain, United States, France, Netherlands
ImmunoGen, Inc.

Completed

Study of Mirvetuximab Soravtansine in Combination With Bevacizumab, Carboplatin, Pegylated Liposomal Doxorubicin, Pembrolizumab, or Bevacizumab + Carboplatin in Participants With Folate Receptor Alpha (FRα) Positive Advanced Epithelial Ovarian Cancer, Primary Peritoneal, or Fallopian Tube Cancer

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Cancer

United States, Spain, Belgium, Canada
Grupo Espanol de Tumores Neuroendocrinos

Completed

Radiological Response of Pancreatic Neuroendocrine Tumors: Comparison Between the Choi and the RECIST Criteria (CRIPNET)

Pancreatic Neuroendocrine Tumors

Spain
Grupo Espanol de Tumores Neuroendocrinos
Gilead Sciences; MFAR

Not yet recruiting

Sacituzumab govitEcan in THYroid Cancers (SETHY)

Differentiated Thyroid Cancer | Anaplastic Thyroid Cancer

Spain
Cytori Therapeutics

Completed

Study of Autologous Fat Enhanced w/ Regenerative Cells Transplanted to Reconstruct Breast Deformities After Lumpectomy (RESTORE-2)

Breast Neoplasms | Carcinoma, Ductal, Breast | Mammaplasty | Mastectomy, Segmental, Lumpectomy, Breast Reconstruction,

Spain, United Kingdom, Belgium, Italy
Glycotope GmbH

Completed

PankoMab-GEX™ Versus Placebo as Maintenance Therapy in Advanced Ovarian Cancer

Fallopian Tube Cancer | Primary Peritoneal Cancer | Ovarian Epithelial Cancer Recurrent

Germany, Hungary, Italy, Poland, Romania, Russian Federation, Spain, United Kingdom
GlaxoSmithKline

Completed

A Study Of Lapatinib Versus Placebo Followed By Chemoradiation In Patients With Locally Advanced Head And Neck Cancer

Squamous Cell Carcinoma of Head and Neck

Spain, France, Peru, India, Greece
Grupo Espanol de Investigacion en Sarcomas

Completed

Trial of Nab-paclitaxel in Patients With Desmoid Tumors and Multiply Relapsed/Refractory Desmoplastic Small Round Cell Tumors and Ewing Sarcoma (ABRADES)

Sarcoma | Sarcoma, Ewing | Desmoid | Tumor, Desmoplastic Small Round Cell, Adult | Tumor, Desmoplastic Small Round Cell, Childhood

Spain
Enterome
Covance

Active, not recruiting

First-in-Human, Phase 1b/2a Trial of a Multipeptide Therapeutic Vaccine in Patients With Progressive Glioblastoma (ROSALIE)

Glioblastoma, Adult

United States, Spain, France, Germany
Hospital Universitario Virgen de la Arrixaca

Not yet recruiting

Liver Transplantation for Unresectable GIST Liver Metastases (TRANSGIST)

Liver Diseases | Liver Transplantation | Liver Neoplasms | Gastrointestinal Stromal Tumors | Metastasis | Liver Metastases | Liver Transplant; Complications | Liver Cancer | Liver Transplant Disorder | Liver Carcinoma | GIST, Malignant | GIST | Metastases | Metastatic Liver Cancer | Gastrointestinal Stromal Tumor of... and other conditions

Spain
Novartis Pharmaceuticals

Terminated

Global Study Looking at the Combination of RAD001 and Sorafenib to Treat Patients With Advanced Hepatocellular Carcinoma

Hepatocellular Carcinoma

United States, Spain, Korea, Republic of, Netherlands, Taiwan
Grupo Español de Tratamiento de Tumores de Cabeza...

Active, not recruiting

Spanish Study for Molecular Characterization of Thyroid Carcinoma (MOLTHY)

Differentiated Thyroid Carcinoma | Medullary Thyroid Carcinoma

Spain
MedSIR
Merck Sharp & Dohme LLC

Active, not recruiting

Combination of Pembrolizumab and Lenvatinib, in Pre-treated Thymic CArcinoma paTIents (PECATI)

Metastatic Thymic Carcinoma | Thymoma Type B3

Spain, France, Italy
Salubris Biotherapeutics Inc

Recruiting

Study of JK08 in Patients With Unresectable Locally Advanced or Metastatic Cancer

Melanoma | Clear Cell Renal Cell Carcinoma | Cancer | Hepatocellular Carcinoma | Colorectal Cancer | Pancreatic Adenocarcinoma | Gastric Adenocarcinoma | Metastatic Cancer | Squamous Cell Carcinoma of Head and Neck | Triple Negative Breast Cancer | Advanced Solid Tumor | Epithelial Ovarian Cancer | Non-small Cell... and other conditions

Belgium, Spain
Hoffmann-La Roche

Completed

A Study of Pharmacodynamics of RO5083945 in Patients With Head and Neck Squamous Cell Carcinoma

Head and Neck Cancer

Spain, France, United Kingdom, Netherlands, Italy

Clinical Trials on Epithelial-Mesenchymal Transition in Spain

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