Clinical Trials on Esophageal Diseases

Total 376940 results

European Organisation for Research and Treatment...

Terminated

Combination of Chemoradiation With Immunotherapy in Inoperable œsophageal Cancer (CRUCIAL)

Inoperable œsophageal Cancer

Spain, France
Grubnik Volodymyr

Completed

Influence of Wrap Fixation Technique on the Results of Fundoplication

Gastro Oesophageal Reflux Disease
Imperial College London

Completed

Physical Activity and Gastrointestinal Investigations

Gastro-oesophageal Reflux Disease

United Kingdom
AIO-Studien-gGmbH
Bristol-Myers Squibb

Completed

A Multicenter Open-label Phase II Trial to Evaluate Nivolumab and Ipilimumab for 2nd Line Therapy in Elderly Patients With Advanced Esophageal Squamous Cell Cancer (RAMONA)

Esophageal Cancer | Gastrooesophageal Cancer | Oesophageal Cancer | GastroEsophageal Cancer | Esophageal Cancers NOS | Oesophageal Cancer Metastatic | Esophageal Cancer Metastatic | Oesophageal Cancer Nos

Germany
Institute of Child Health

Completed

Laparoscopy in Children: Does it Decrease the Metabolic, Endocrine and Inflammatory Stress Response to Surgery

Gastro-Oesophageal Reflux

United Kingdom
Norgine

Completed

A Three-Period Study to Investigate the Relative Bioavailability and Pharmacodynamic Profiles of a Zegerid 20mg Capsule, Zegerid 20mg Powder for Oral Suspension and Losec 20mg Capsule in Healthy Adult Volunteers Under Fasting Conditions

Acid Reflux | Gastro Oesophageal Reflux Disease

United Kingdom
Imperial College London

Active, not recruiting

The Bacterial Composition of the Stomach in Reflux Disease

Gastric Cancer | Esophagitis | Gastro Esophageal Reflux | Barrett Esophagus | Oesophageal Cancer | GORD | Oesophageal Reflux | Oesophageal Carcinoma

United Kingdom
Cancer Trials Ireland

Completed

A Phase II Trial of Epirubicin, Oxaliplatin and Capecitabine (EOX) Versus Docetaxel and Oxaliplatin (ElTax) in the Treatment of Advanced Gastro-oesophageal Cancer (ELECT)

Gastro Oesophageal Cancer

Ireland
Imperial College London
Imperial College Healthcare NHS Trust

Recruiting

Volatile Organic Compounds as Breath Biomarkers in Squamous Oesophageal Neoplasms (ViSON)

Oesophageal Squamous Cell Carcinoma | Oesophageal Cancer

United Kingdom
Australasian Gastro-Intestinal Trials Group
National Health and Medical Research Council, Australia; Canadian Cancer Trials... and other collaborators

Active, not recruiting

A Study of Regorafenib in Refractory Advanced Gastro-Oesophageal Cancer (INTEGRATEIIa)

Gastro-Oesophageal Cancer

Korea, Republic of, Australia, Taiwan, New Zealand, United States, Canada, Japan
University of Liege

Not yet recruiting

Determination of the Left Paratrachéal Force Required to Occlude the Esophageal Entrance

Oesophageal Reflux
Radboud University Medical Center
Erasmus Medical Center

Terminated

Esophageal Multisegmented FCSEMS for Malignant Strictures (EATERS)

Oesophageal Cancer | Esophageal Stent Stenosis

Netherlands
UMC Utrecht
Karolinska University Hospital; Erasmus Medical Center; Great Ormond Street Hospital... and other collaborators

Not yet recruiting

Primary Posterior Tracheopexy Prevents Tracheal Collapse (PORTRAIT)

Oesophageal Atresia | Tracheomalacia | Oesophageal Atresia With Tracheo-Oesophageal Fistula
Showa Inan General Hospital

Withdrawn

Elemental Diets vs. Semi-solid Diets on Gastric Excretion and Gastroesophageal Regurgitation

Gastro-oesophageal Reflux

Japan
SOFAR S.p.A.

Completed

Evaluation of GERDOFF Efficacy in Combination With Proton Pump Inhibitor

Gastro-oesophageal Reflux Disease

Italy
Sun Yat-sen University
Affiliated Cancer Hospital of Shantou University Medical College

Recruiting

PD-1 Inhibitor Combined With Neoadjuvant Chemoradiotherapy Plus Surgery for Locally Advanced ESCC (NEOCRTEC2101)

Esophageal Cancer | Oesophageal Cancer | Squamous Cell Esophageal Carcinoma

China
University Hospital, Lille

Recruiting

Study of the Effect of the Time of Diagnosis (Antenatal vs. Postnatal) on the Post-traumatic Reactions of Parents of Children Undergoing Oesophageal Atresia Surgery " (DANAO)

Atresia, Esophageal

France
Assistance Publique Hopitaux De Marseille

Unknown

Correlation Between Clinical Signs and High-resolution Manometry Data in Children

Oesophageal Motility Disorder

France
Manchester University NHS Foundation Trust

Completed

A Validation Study of the Dx-pH Probe in Children for the Detection of Extra-oesophageal Reflux

Gastro-oesophageal Reflux

United Kingdom
Ludwig Institute for Cancer Research
AstraZeneca

Completed

Study of Anti-PD-L1 in Combination With Chemo(Radio)Therapy for Oesophageal Cancer

Esophageal Cancer

United Kingdom
Studio Osteopatico Busto Arsizio

Recruiting

Osteopathic Manipulative Treatment for Gastro-oesophageal Reflux Disease

Gastro-oesophageal Reflux Disease

Italy
Reckitt Benckiser Healthcare (UK) Limited

Completed

Clinical Investigation to Assess the Acid Neutralisation Activity of a Calcite Chewing Gum

Esophagitis | Gastro Oesophageal Reflux Disease

Ireland
Lisette Nixon
Cancer Research UK

Recruiting

Study of Chemoradiotherapy in Oesophageal Cancer Including PET Response and Dose Escalation (SCOPE2)

Oesophageal Cancer

United Kingdom
Simon C Pacey, MD
AstraZeneca

Active, not recruiting

Do Changes in ctDNA Predict Response for Patients With Oesophageal Cancer Receiving Durvalumab (CALIBRATION)

Oesophageal Cancer

United Kingdom
Peter MacCallum Cancer Centre, Australia

Terminated

A Study of APR-246 in Oesophageal Cancer (APROC)

Oesophageal Carcinoma

Australia
Lisette Nixon
Cancer Research UK

Unknown

A Feasibility Study of Chemo-radiotherapy to Treat Operable Oesophageal Cancer (NeoSCOPE)

Oesophageal Cancer

United Kingdom
Australasian Gastro-Intestinal Trials Group

Recruiting

A Trial of Palliative Chemotherapy, Radiation and Immune Treatment for Oesophageal Cancer: PALEO Study (PALEO)

Oesophageal Cancer

Australia, New Zealand
University of Oxford
Cambridge University Hospitals NHS Foundation Trust; Centre for Statistics... and other collaborators

Completed

Cytosponge™ for Post-Chemoradiation Surveillance of Oesophageal Cancer (CYTOFLOC)

Oesophageal Cancer

United Kingdom
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Terminated

A Study of Donafenib Monotherapy in Advanced Oesophageal Cancer

Oesophageal Cancer

China
AstraZeneca

Completed

PPI Sequencing Study

Gastro-Oesophageal Reflux Disease

United Kingdom
University of Luebeck
Dr.Ahmad Keelani

Not yet recruiting

PrOgnosis Following Esophageal fisTula formaTion in Pts Undergoing cathetER Ablation for AF Study (POTTER)

Atrial Fibrillation | Catheter Ablation | PVI | Atrio-Oesophageal Fistula
Meyer Children's Hospital IRCCS

Recruiting

A Study of Patients Undergoing Surgical Treatment for Oesophageal Atresia

Atresia Esophagus

Italy
Sanofi
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of SAR444245 Combined With Other Anticancer Therapies for the Treatment of Participants With Gastrointestinal Cancer (Master Protocol) (Pegathor Gastrointestinal 203)

Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Oesophageal Adenocarcinoma | Oesophageal Squamous Cell Carcinoma

Korea, Republic of, Belgium, Italy, United States, Chile, China, France, Netherlands, Spain
Janssen-Cilag International NV

Completed

Observational Study (This Means That no Drug is Tested) in Patients Suffering of Gastroesophageal Reflux Disease. (PROFILE)

Gastroesophageal Reflux Disease | GERD | Gastro-oesophageal Reflux | Gastro-Esophageal Reflux | Esophageal Reflux
Mirai Medical
Nottingham University Hospitals NHS Trust

Completed

EndoVE endosCopic Treatment for Oesophageal and Gastric canceR (VECTOR)

Gastric Cancer | Oesophageal Cancer | Oesophageal Disease

United Kingdom
University Hospital, Lille
University of Lille Nord de France

Active, not recruiting

Determinants of Patient Delay in Doctor Consultation in Oeso-gastric Cancers (DELOGAST)

Gastric Adenocarcinoma | Oesophageal Carcinoma

France
Royal Marsden NHS Foundation Trust

Unknown

Determination of the Role of Microarray for Prognosis and Prediction to Chemotherapy Sensitivity in Patients With Operable, Locally Advanced and Metastatic Oesophageal Cancer

Oesophageal Cancer

United Kingdom
Bas P. L. Wijnhoven

Recruiting

Surgery As Needed for Oesophageal Cancer - 2 (SANO-2)

Cancer of Esophagus

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...
Noordwest Ziekenhuisgroep

Active, not recruiting

Blood-borne Assessment of Stromal Activation in Esophageal Adenocarcinoma to Guide Tocilizumab Therapy (BASALT)

Oesophageal Adenocarcinoma | Esophageal Adenocarcinoma | Resectable Carcinoma

Netherlands
UNICANCER

Recruiting

Association of Radiochemotherapy and Immunotherapy for the Treatment of Unresectable Oesophageal caNcer (ARION)

Esophagus Cancer | Unresectable Malignant Neoplasm

France
Centre Hospitalier Departemental Vendee

Recruiting

Evaluation of Omentopexy on Gastro-oesophageal Reflux Following Sleeve Gastrectomy (Sleevepexie)

Obesity

France
Erasme University Hospital

Terminated

Endomina Diverticulum

Oesophageal Disease

Belgium
Sun Yat-sen University

Active, not recruiting

Study of Docetaxel or Vinorelbine Plus Cisplatin in Neoadjuvant Chemoradiotherapy for Esophageal Cancer (NEOCRTEC308)

Esophageal Cancer | Esophageal Squamous Cell Carcinoma | Oesophageal Cancer

China
Institut Paoli-Calmettes
Cook medical laboratory

Completed

Placing Trust in Endoscopic Ultrasonography: Impact on Planning Conformal Radiotherapy of Cancer of the Esophagus and Rectum (FIDUCOR)

Rectal Cancer | Oesophageal Cancer

France
Birmingham Women's and Children's NHS Foundation...

Not yet recruiting

Use of Indocyanine Green During Primary Repair of Oesophageal Atresia and Distal Tracheo-oesophageal Fistula (iTOF)

Tracheo-Esophageal Fistula With Atresia of Esophagus

United Kingdom
Academisch Medisch Centrum - Universiteit van Amsterdam...
University Medical Center Groningen; UMC Utrecht; Erasmus Medical Center; Catharina... and other collaborators

Recruiting

TGF-β And PDL-1 Inhibition in Esophageal Squamous Cell Carcinoma Combined With Chemoradiation TheRapY (TAPESTRY)

Carcinoma, Squamous Cell | Oesophageal Cancer

Netherlands
Hospital Authority, Hong Kong
The University of Hong Kong

Unknown

A Study of the Use of High-dose Proton Pump Inhibitor for the Treatment of Gastro-oesophageal Reflux Related Non-cardiac Chest Pain - a Randomized Double-blind Placebo-controlled Study

Chest Pain

China
Lisette Nixon

Completed

ROCS (Radiotherapy After Oesophageal Cancer Stenting) Study (ROCS)

Oesophageal Cancer

United Kingdom
Imperial College London
Barking, Havering and Redbridge University Hospitals NHS Trust; Imperial College... and other collaborators

Recruiting

Profiling Microbiome Associated Metabolic Pathways in Oesophageal Cancer Survivors (MAPLES)

Quality of Life | Oesophageal Cancer | Bacterial Overgrowth

United Kingdom
University Hospital, Bordeaux

Completed

Benefit of Pharyngeal and Oesophageal pH-impedance of Patients With High Suspicion of Laryngopharyngeal Reflux (PHARO)

Laryngopharyngeal Reflux | Oesophageal pH-impedance

France

Clinical Trials on Esophageal Diseases

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Russia

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Rare Diseases

Drug Interventions

Dietary Supplements

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